Compounds > 4-butyrolactone
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4-butyrolactone and phenobarbital

4-butyrolactone has been researched along with phenobarbital in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baker, K; Clifford, DB; Covey, DF; Yang, J; Zorumski, CF1
Czarnecki, R; Sobański, H1
Bolos-Sy, AM; Covey, DF; Ferrendelli, JA; Mathews, GC; Rothman, SM1
Covey, DF; Ferrendelli, JA; Krause, JE; Rothman, SM; Tucker, JB; Weiss, DS; White, G; Williams, KL1
Ball, HW; Manson, MM; McLellan, LI; Shepherd, AG1
Clark, RF; Ly, BT; Schneir, AB1
Amore, M; Belvederi Murri, M; Cervetti, A; Ghio, L; Respino, M1

Reviews

1 review(s) available for 4-butyrolactone and phenobarbital

ArticleYear
Management and treatment of gamma butyrolactone withdrawal syndrome: a case report and review.
    Journal of psychiatric practice, 2014, Volume: 20, Issue:4

    Topics: 4-Butyrolactone; Adult; Barbiturates; Humans; Male; Phenobarbital; Solvents; Substance Withdrawal Syndrome; Treatment Outcome

2014

Other Studies

6 other study(ies) available for 4-butyrolactone and phenobarbital

ArticleYear
Alpha-substituted thiobutyrolactones potentiate GABA currents in voltage-clamped chick spinal cord neurons.
    Neuroscience letters, 1988, Apr-22, Volume: 87, Issue:1-2

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Cells, Cultured; Chick Embryo; Diazepam; Furans; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Phenobarbital; Picrotoxin; Spinal Cord

1988
Anticonvulsive properties of 5-allyl-(beta-hydroxy)propyl-N-phenylbarbituric acid and the corresponding lactone.
    Il Farmaco; edizione scientifica, 1980, Volume: 35, Issue:11

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Barbiturates; Convulsants; Electroshock; Furans; Lethal Dose 50; Male; Mice; Phenobarbital; Seizures

1980
Physiological comparison of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone with benzodiazepine and barbiturate modulators of GABAA receptors.
    Neuropharmacology, 1996, Volume: 35, Issue:2

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Binding Sites; Cells, Cultured; Chlordiazepoxide; Chlorine; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Patch-Clamp Techniques; Phenobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Transfection

1996
Lactone modulation of the gamma-aminobutyric acid A receptor: evidence for a positive modulatory site.
    Molecular pharmacology, 1997, Volume: 52, Issue:1

    Topics: 4-Butyrolactone; Animals; Chlordiazepoxide; Female; Flumazenil; gamma-Aminobutyric Acid; Lactones; Phenobarbital; Picrotoxin; Receptors, GABA-A; Xenopus laevis

1997
Regulation of rat glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) subunits by chemopreventive agents and in aflatoxin B(1)-induced preneoplasia.
    Carcinogenesis, 2000, Volume: 21, Issue:10

    Topics: 4-Butyrolactone; Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catalytic Domain; Coumarins; Diet; Ellagic Acid; Enzyme Induction; Ethoxyquin; Glutamate-Cysteine Ligase; Glutathione; Inactivation, Metabolic; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Wistar

2000
A case of withdrawal from the GHB precursors gamma-butyrolactone and 1,4-butanediol.
    The Journal of emergency medicine, 2001, Volume: 21, Issue:1

    Topics: 4-Butyrolactone; Adult; Anticonvulsants; Diazepam; Drug Therapy, Combination; Emergencies; Humans; Lorazepam; Male; Phenobarbital; Substance Withdrawal Syndrome; United States

2001