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4-butyrolactone and malonyl coenzyme a

4-butyrolactone has been researched along with malonyl coenzyme a in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kuhajda, FP; Landree, LE; Ronnett, GV; Thupari, JN1
Hirsch, J1
Clegg, DJ; D'Alessio, D; Seeley, RJ; Woods, SC; Wortman, MD1
Cha, SH; Chohnan, S; Hu, Z; Lane, MD2
Burris, L; Hammond, C; Kays, JS; Seng, TW; Skillman, TR; Yang, N1
González, S; Haro, D; Llebaria, A; Marrero, PF; Napal, L; Nicot, C; Relat, J; Woldegiorgis, G1
Cheng, D; Rendina, AR1
Cha, SH; Chohnan, S; Lane, MD; Puigserver, P; Rodgers, JT1
Downs, SM; Klinger, J; Mosey, JL1

Other Studies

10 other study(ies) available for 4-butyrolactone and malonyl coenzyme a

ArticleYear
C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Jul-09, Volume: 99, Issue:14

    Topics: 3T3 Cells; 4-Butyrolactone; Adenosine Triphosphate; Adipocytes; Animals; Carnitine O-Palmitoyltransferase; Diet; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Fatty Acid Synthases; Fatty Acids; Humans; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Obesity; Oxidation-Reduction; Tumor Cells, Cultured; Weight Loss

2002
The search for new ways to treat obesity.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Jul-09, Volume: 99, Issue:14

    Topics: 4-Butyrolactone; Adipose Tissue; Animals; Carnitine O-Palmitoyltransferase; Cell Size; Cerulenin; Energy Intake; Fatty Acids; Ghrelin; Humans; Malonyl Coenzyme A; Obesity; Peptide Hormones; Peptides

2002
C75 inhibits food intake by increasing CNS glucose metabolism.
    Nature medicine, 2003, Volume: 9, Issue:5

    Topics: 4-Butyrolactone; Animals; Appetite Depressants; Brain; Eating; Fatty Acid Synthases; Glucose; Humans; Malonyl Coenzyme A

2003
Hypothalamic malonyl-CoA as a mediator of feeding behavior.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Oct-28, Volume: 100, Issue:22

    Topics: 4-Butyrolactone; Animals; Fasting; Fatty Acid Synthases; Feeding Behavior; Hypothalamus; Injections, Intraventricular; Male; Malonyl Coenzyme A; Mice; Mice, Inbred BALB C

2003
C75 [4-methylene-2-octyl-5-oxo-tetrahydro-furan-3-carboxylic acid] activates carnitine palmitoyltransferase-1 in isolated mitochondria and intact cells without displacement of bound malonyl CoA.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:1

    Topics: 4-Butyrolactone; Animals; Carnitine O-Palmitoyltransferase; Enzyme Activation; Humans; Malonyl Coenzyme A; Mitochondria, Heart; Rats; Recombinant Proteins; Tumor Cells, Cultured; Yeasts

2005
C75 activates malonyl-CoA sensitive and insensitive components of the CPT system.
    Biochemical and biophysical research communications, 2004, Dec-17, Volume: 325, Issue:3

    Topics: 4-Butyrolactone; Animals; Carnitine O-Palmitoyltransferase; Enzyme Activation; Humans; Malonyl Coenzyme A; Pichia; Rats; Recombinant Proteins

2004
Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates.
    The Biochemical journal, 2005, Jun-15, Volume: 388, Issue:Pt 3

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; 4-Butyrolactone; Acetyl Coenzyme A; Alcohol Oxidoreductases; Animals; Binding, Competitive; Dithiothreitol; Enzyme Activation; Fatty Acid Synthases; Kinetics; Liver; Malonyl Coenzyme A; NADP; Rats; Substrate Specificity; Temperature

2005
Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Oct-11, Volume: 102, Issue:41

    Topics: 4-Butyrolactone; Animals; Blotting, Western; Carnitine O-Palmitoyltransferase; Carrier Proteins; DNA Primers; Fatty Acid Synthases; Fatty Acids; Hypothalamus; Ion Channels; Malonyl Coenzyme A; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Muscle, Skeletal; Oxidation-Reduction; Polymerase Chain Reaction; PPAR alpha; Signal Transduction; Sympathetic Nervous System; Uncoupling Protein 3

2005
Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Oct-17, Volume: 103, Issue:42

    Topics: 4-Butyrolactone; Animals; Cells, Cultured; Energy Metabolism; Fatty Acid Synthases; Gene Expression Regulation; Hypothalamus; Male; Malonyl Coenzyme A; Mice; Mice, Inbred BALB C; Mitochondria; Muscle, Skeletal; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Signal Transduction; Trans-Activators; Transcription Factors

2006
Fatty acid oxidation and meiotic resumption in mouse oocytes.
    Molecular reproduction and development, 2009, Volume: 76, Issue:9

    Topics: 4-Butyrolactone; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cerulenin; Cumulus Cells; Epoxy Compounds; Fatty Acids; Female; Malonyl Coenzyme A; Meiosis; Mice; Mice, Inbred C57BL; Oocytes; Oxidation-Reduction; Palmitic Acid; Ribonucleotides

2009