Compounds > 4-butyrolactone
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4-butyrolactone and kme 4

4-butyrolactone has been researched along with kme 4 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hidaka, T; Hosoe, K; Katsumi, I; Watanabe, K; Yamashita, T1
Fujimura, H; Hidaka, T; Hiramatsu, Y; Hosoe, K; Watanabe, K; Yamashita, T1
Hidaka, T; Hosoe, K; Katsumi, I; Kondo, H; Watanabe, K; Yamashita, K; Yamashita, T1
Hidaka, T; Hosoe, K; Watanabe, K; Yamashita, T1
Hidaka, T; Hosoe, K; Katsumi, I; Takeo, K; Watanabe, K; Yamashita, T1
Ariki, Y; Hidaka, T; Hosoe, K; Katsumi, I; Kondo, H; Takeo, K; Watanabe, K; Yamashita, K; Yamashita, T1

Other Studies

6 other study(ies) available for 4-butyrolactone and kme 4

ArticleYear
The effect of alpha-(3,5-di-t-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), a new anti-inflammatory drug, on leucocyte migration in rat carrageenan pleurisy.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:3

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Migration Inhibition; Furans; Leukocytes; Male; Pleurisy; Rats; Rats, Inbred Strains; Time Factors

1986
Analgesic and anti-inflammatory activities in rats of alpha-(3,5-di-t-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), and its intestinal damage.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:10

    Topics: 4-Butyrolactone; Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capillary Permeability; Edema; Furans; Ibuprofen; Indomethacin; Intestinal Diseases; Lethal Dose 50; Male; Naproxen; Rats; Rats, Inbred Strains

1986
Studies on styrene derivatives. I. Synthesis and antiinflammatory activities of alpha-benzylidene-gamma-butyrolactone derivatives.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:1

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Benzylidene Compounds; Chemical Phenomena; Chemistry; Furans; Rats

1986
Effect of alpha-(3,5-di-tert-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), a new anti-inflammatory drug, on the established adjuvant arthritis in rats.
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:2

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Blood Proteins; Blood Sedimentation; Body Weight; Bone and Bones; Furans; Indomethacin; Male; Organ Size; Radiography; Rats; Rats, Inbred Strains

1986
Inhibition of polymorphonuclear leukocyte 5-lipoxygenase and platelet cyclooxygenase by alpha-(3,5-di-tert-butyl-4-hydroxybenzylidene)-gamma-butyrolacto ne (KME-4), a new anti-inflammatory drug.
    Japanese journal of pharmacology, 1985, Volume: 38, Issue:3

    Topics: 4-Butyrolactone; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Arachidonate Lipoxygenases; Blood Platelets; Calcimycin; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Furans; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Neutrophils; Pyrazoles; Rabbits

1985
Pharmacological properties of a new anti-inflammatory compound, alpha-(3,5-di-tert-butyl-4-hydroxybenzylidene)-gamma-butyrolacto ne (KME-4), and its inhibitory effects on prostaglandin synthetase and 5-lipoxygenase.
    Japanese journal of pharmacology, 1984, Volume: 36, Issue:1

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Edema; Furans; Granuloma; Lipoxygenase Inhibitors; Male; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Stomach Ulcer

1984