4-butyrolactone has been researched along with isochaihulactone in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, JY; Chang, WL; Chen, SP; Chen, YL; Cheng, YL; Harn, HJ; Lin, SZ; Tsai, NM | 1 |
| Chang, WL; Chen, SP; Chen, YL; Cheng, YL; Harn, HJ; Lin, CC; Lin, PC; Lin, SZ; Tsai, NM | 1 |
| Alizadeh, BH; Ardestani, SK; Emami, S; Foroumadi, A; Khoobi, M; Panah, F; Shafiee, A | 1 |
| CHAN, DC; CHEN, YL; CHIEN, MH; HARN, HJ; LIN, CC; LIN, CJ; LIN, SB; SU, KJ; WAY, TD; YIANG, GT; YU, SL; YU, YL | 1 |
| Chen, CJ; Chen, YL; Harn, HJ; Lin, CJ; Lin, SZ; Su, KJ; Wei, CW; Yiang, GT; Yu, YL | 1 |
| Chen, SP; Chen, YL; Chiu, SC; Harn, HJ; Huang, SY; Lin, SZ; Pang, CY; Wang, MJ; Yang, HH | 1 |
| Chiou, TW; Chou, YW; Harn, HJ; Huang, MH; Lin, CT; Lin, PC; Lin, SZ; Liu, PY; Sheu, JJ | 1 |
| Chiou, TW; Harn, HJ; Ho, LI; Lin, SZ; Su, HL; Tao, M; Tsai, SF | 1 |
| Chang, CM; Chen, YS; Chen, YT; Chern, J; Fang, Z; Hua, KF; Lam, Y; Lu, CP; Ng, CY; Wu, SH | 1 |
9 other study(ies) available for 4-butyrolactone and isochaihulactone
| Article | Year |
|---|---|
In vitro and in vivo studies of a novel potential anticancer agent of isochaihulactone on human lung cancer A549 cells.
Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzodioxoles; Bupleurum; Cell Line, Tumor; Cell Proliferation; Cell Shape; Dose-Response Relationship, Drug; G2 Phase; Humans; Inhibitory Concentration 50; Lignans; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Microtubules; Phosphorylation; Plant Extracts; Plant Roots; Tubulin; Weight Gain; Xenograft Model Antitumor Assays | 2006 |
Activation of nonsteroidal anti-inflammatory drug-activated gene-1 via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase revealed a isochaihulactone-triggered apoptotic pathway in human lung cancer A549 cells.
Topics: 4-Butyrolactone; Antineoplastic Agents; Apoptosis; Benzodioxoles; Cell Line, Tumor; Cytokines; Early Growth Response Protein 1; Gene Expression Regulation; Growth Differentiation Factor 15; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligonucleotide Array Sequence Analysis; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic | 2007 |
Isochaihulactone analogues: synthesis and anti-proliferative activity of novel dibenzylbutyrolactones.
Topics: 4-Butyrolactone; Antitubercular Agents; Benzodioxoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2010 |
Isochaihulactone protects PC12 cell against H(2)O(2) induced oxidative stress and exerts the potent anti-aging effects in D-galactose aging mouse model.
Topics: 4-Butyrolactone; Adenosine Diphosphate Ribose; Aging, Premature; Animals; Antioxidants; Apoptosis; Benzodioxoles; Bupleurum; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Galactose; Glutathione Peroxidase; Hydrogen Peroxide; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2010 |
Synergistic anti-tumor activity of isochaihulactone and paclitaxel on human lung cancer cells.
Topics: 4-Butyrolactone; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzodioxoles; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Growth Differentiation Factor 15; Humans; Immunohistochemistry; Lung Neoplasms; MAP Kinase Signaling System; Paclitaxel | 2012 |
Activation of NAG-1 via JNK signaling revealed an isochaihulactone-triggered cell death in human LNCaP prostate cancer cells.
Topics: 4-Butyrolactone; Anthracenes; Benzodioxoles; Blotting, Western; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Growth Differentiation Factor 15; Humans; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Signal Transduction; Tumor Suppressor Protein p53 | 2011 |
Regulation of androgen receptor expression by Z-isochaihulactone mediated by the JNK signaling pathway and might be related to cytotoxicity in prostate cancer.
Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Apoptosis; Benzodioxoles; Cell Line, Tumor; Cytotoxins; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Prostatic Neoplasms; Receptors, Androgen; Transcription, Genetic; Xenograft Model Antitumor Assays | 2013 |
Isochaihulactone-induced DDIT3 causes ER stress-PERK independent apoptosis in glioblastoma multiforme cells.
Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Benzodioxoles; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Glioblastoma; Growth Differentiation Factor 15; Humans; Mice; Transcription Factor CHOP; Treatment Outcome; Xenograft Model Antitumor Assays | 2017 |
Affinity-Driven Covalent Modulator of the Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Cascade.
Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Apoptosis; Benzodioxoles; Cell Line, Tumor; Drug Resistance, Neoplasm; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Mice; Models, Molecular; Neoplasms; Signal Transduction; Tandem Mass Spectrometry | 2018 |