Page last updated: 2024-08-18

4-butyrolactone and hinokinin

4-butyrolactone has been researched along with hinokinin in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	15 (40.54)	29.6817
2010's	17 (45.95)	24.3611
2020's	5 (13.51)	2.80

Authors

Authors	Studies
Chang, C; Chen, CC; Hsu, FL; Huang, RL; Huang, YL; Ou, JC	1
Bastos, JK; da Silva, GV; da Silva, R; de Albuquerque, S; Donate, PM; Heleno, VC; Lopes, JL; Pedersoli, S; Silva, ML	1
Fukuyama, T; Inouye, T; Morimoto, K; Nishitani, S; Ryu, I	1
Alfermann, AW; Bayindir, U; Fuss, E; Mehregan, I; Mohagheghzadeh, A; Schmidt, TJ	1
Aguilar-Guadarrama, AB; Gutiérrez, Mdel C; Rios, MY	1
Albuquerque, S; Andrade E Silva, ML; Bastos, JK; Cintra, VP; da Silva, R; de Andrade Royo, V; Medola, JF; Pesqueira E Silva, EP; Saraiva, J; Tavares, DC	1
Almeida, VA; Bastos, JK; Carvalho, TC; Coímbra, HS; Costa, ES; Cunha, WR; Filho, AA; Furtado, NA; Lima, TC; Martins, CH; Pereira, AC; Royo, VA; Silva, ML; Silva, R; Vinhólis, AH	1
Albuquerque, S; da Silva, R; Donate, PM; Ferreira, MM; Kiralj, R	1
Benedettelli, S; Bosi, S; Carrasco-Pancorbo, A; Cortacero-Ramírez, S; Dinelli, G; Fernández-Gutiérrez, A; Ghiselli, L; Marotti, I; Segura-Carretero, A	1
Nersesyan, AK	1
Gao, HY; Ikeda, R; Kawahara, N; Kuroyanagi, M; Muto, N; Nakane, T; Otaki, K; Sano, T	1
Alfermann, AW; Bayindir, U; Fuss, E	1
Dominguez, OP; Higuchi, Y; Horie, S; Ishikawa, T; Kumamoto, T; Matsumoto, K; Mochizuki, M; Nakanishi, W; Shimokawa, S; Tashima, K; Watanabe, T; Zhang, G	1
Chen, JF; Chen, JJ; Chung, CY; Hwang, TL	1
Duan, HQ; Tang, SA; Zhang, W	1
Bastos, JK; da Silva Ferreira, D; de Albuquerque, S; de Gaitani, CM; E Silva, ML; Esperandim, VR; Ferraudo, AS; Lira, AA; Marchetti, JM; Saraiva, J	1
Bastos, JK; Costa, ES; da Silva Ferreira, D; de Albuquerque, S; Esperandim, VR; Pereira, AC; Saraiva, J; Silva, ML	1
Andrade E Silva, ML; Barbosa, LC; Bastos, JK; Furtado, RA; Pereira, AC; Ponce, M; Resende, FA; Tavares, DC; Tomazella, IM	1
Ferreira, MJ; Mansoor, TA; Ramalho, RM; Rodrigues, CM	1
Andrade E Silva, ML; Bastos, JK; Cunha, WR; da Silva Ferreira, D; de Albuquerque, S; Esperandim, VR; Saraiva, J; Sousa Rezende, KC	1
Barbosa, LC; de Camargo, MS; de Souza Rezende, KC; E Silva, ML; Resende, FA; Tavares, DC; Varanda, EA	1
Bastos, JK; Cunha, WR; da Silva Ferreira, D; de Albuquerque, S; e Silva, ML; Esperandim, VR; Rezende, KC; Saraiva, J	1
Bai, G; Cao, XL; Liu, Y; Tang, YL; Xiang, JF; Xu, J; Zhang, H	1
Andrade e Silva, ML; Cunha, WR; Fontana, AC; Magalhães, LG; Mortensen, OV; Pereira, AC; Souza Rezende, KC; Timple, JM	1
Almeida, A; Desai, DC; Jacob, J; Kshirsagar, R; Manju, SL	1
Curini, M; Marcotullio, MC; Pelosi, A	1
Andrade e Silva, ML; Barbosa, LC; Bastos, JK; Bertanha, HC; Costa, ES; Furtado, RA; Tavares, DC; Tomazella, IM	1
Albert, A; Hunsche, M; Lankes, C; Müller, V; Noga, G; Winkler, JB; Zimmermann, BF	1
Adfa, M; Koketsu, M; Ninomiya, M; Rahmad, R; Tanaka, K; Yudha S, S	1
Cunha, NL; Dos Santos, RA; Gonçalves, Ndos S; Martins, TD; Oliveira, PF; Rezende, KC; Silva, ML; Símaro, GV; Souza, AR; Souza, DG; Tavares, DC; Teixeira, GM	1
Andriani, KF; Bastos, JK; Borges, A; Borges, CHG; Caramori, GF; Conforti, VA; Cunha, WR; da Silva Laurentiz, R; de Andrade, CQJ; E Silva, MLA; Januário, AH; Lima, TC; Lucarini, R; Parreira, RLT; Pauletti, PM; Símaro, GV; Souza, AMP; Volpe, AC	1
Borges, A; Casoti, R; da Cunha, NL; da Rocha Pissurno, AP; da Silva de Laurentiz, R; E Silva, MLA; Kawano, DF	1
Blé-González, EA; Córdova-de la Cruz, M; Gómez-Rivera, A; González-Cortázar, M; Lobato-García, CE; López-Rodríguez, R; Montiel-Ruiz, RM; Zamilpa, A	1
Bian, J; Du, J; Liu, Z; Lu, Q; Zheng, R; Zhu, P	1
Ambrósio, SR; Braun, GH; de Souza, JM; Dias, GM; Januário, AH; Pauletti, PM; Pedroso, RCN; Pietro, RCLR; Pimenta, LP; Ramos, HP; Santos, MFC; Silva, MLA; Siqueira, KA; Soares, MA; Veneziani, RCS	1
Borges, A; de Laurentiz, RDS; de Lima, RG; Dos Santos, FF; E Silva, MLA; Lisoni, FCR; Molina, EF; Orenha, RP; Parreira, RLT; Picão, TB; Santos, MFC	1
Bian, Y; Bobek, KB; Ezzat, NS; Jones, BS; Jurca, T; Li, H; Shaw, TE; Yuan, Y	1

Reviews

1 review(s) available for 4-butyrolactone and hinokinin

Article	Year
Hinokinin, an emerging bioactive lignan. Molecules (Basel, Switzerland), 2014, Sep-17, Volume: 19, Issue:9 Topics: 4-Butyrolactone; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Antiparasitic Agents; Benzodioxoles; Dioxoles; Humans; Lignans; Plant Extracts	2014

Other Studies

36 other study(ies) available for 4-butyrolactone and hinokinin

Article	Year
Screening of 25 compounds isolated from Phyllanthus species for anti-human hepatitis B virus in vitro. Phytotherapy research : PTR, 2003, Volume: 17, Issue:5 Topics: 4-Butyrolactone; Anisoles; Benzodioxoles; Culture Techniques; Dioxoles; Enzyme-Linked Immunosorbent Assay; Glucosides; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Hydrolyzable Tannins; Lignans; Molecular Structure; Phyllanthus; Phytotherapy; Plant Extracts; Tannins	2003
Detailed 1H and 13C NMR structural assignment of three biologically active lignan lactones. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2006, Volume: 63, Issue:1 Topics: 4-Butyrolactone; Benzodioxoles; Carbon Isotopes; Dioxoles; Lactones; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Protons	2006
Effective acceleration of atom transfer carbonylation of alkyl iodides by metal complexes. Application to the synthesis of the hinokinin precursor and dihydrocapsaicin. Organic letters, 2006, Mar-30, Volume: 8, Issue:7 Topics: 4-Butyrolactone; Alkynes; Benzodioxoles; Capsaicin; Dioxoles; Iodides; Lignans; Manganese Compounds; Molecular Structure; Palladium	2006
Diarylbutyrolactone lignans from Linum corymbulosum in vitro cultures. Planta medica, 2006, Volume: 72, Issue:12 Topics: 4-Butyrolactone; Benzodioxoles; Culture Techniques; Dioxoles; Flax; Lignans; Molecular Structure	2006
Analgesic activity of affinin, an alkamide from Heliopsis longipes (Compositae). Journal of ethnopharmacology, 2007, Mar-21, Volume: 110, Issue:2 Topics: 4-Butyrolactone; Alkenes; Amides; Analgesics; Animals; Asteraceae; Benzodioxoles; Brain; Dioxoles; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Lignans; Medicine, Traditional; Methylene Chloride; Mexico; Mice; Pain; Plant Extracts; Plants, Medicinal; Polyunsaturated Alkamides	2007
(-)-Hinokinin causes antigenotoxicity but not genotoxicity in peripheral blood of Wistar rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:4 Topics: 4-Butyrolactone; Animals; Antimutagenic Agents; Benzodioxoles; Chromosome Aberrations; Dioxoles; Doxorubicin; Female; Lignans; Male; Micronucleus Tests; Rats; Rats, Wistar	2007
Evaluation of piper cubeba extract, (-)-cubebin and its semi-synthetic derivatives against oral pathogens. Phytotherapy research : PTR, 2007, Volume: 21, Issue:5 Topics: 4-Butyrolactone; Anti-Infective Agents; Benzodioxoles; Candida albicans; Dioxoles; Enterococcus faecalis; Lignans; Microbial Sensitivity Tests; Piper; Plant Extracts; Streptococcus	2007
Conformational study of (8alpha,8'beta)-bis(substituted phenyl)-lignano-9,9'-lactones by means of combined computational, database mining, NMR, and chemometric approaches. The journal of physical chemistry. A, 2007, Jul-19, Volume: 111, Issue:28 Topics: 4-Butyrolactone; Benzodioxoles; Databases, Factual; Dioxoles; Lignans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Quantum Theory	2007
Lignan profile in seeds of modern and old Italian soft wheat (Triticum aestivum L.) cultivars as revealed by CE-MS analyses. Electrophoresis, 2007, Volume: 28, Issue:22 Topics: 4-Butyrolactone; Benzodioxoles; Butylene Glycols; Dioxoles; Electrophoresis, Capillary; Furans; Italy; Lignans; Seeds; Tandem Mass Spectrometry; Triticum	2007
Re: (-)-Hinokinin causes antigenotoxicity but not genotoxicity in peripheral blood of Wistar rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:3 Topics: 4-Butyrolactone; Animals; Antimutagenic Agents; Benzodioxoles; Chromosome Aberrations; Dioxoles; Lignans; Mutagens; Rats; Rats, Wistar	2008
Neurite outgrowth-promoting active constituents of the Japanese cypress (Chamaecyparis obtusa). Chemical & pharmaceutical bulletin, 2008, Volume: 56, Issue:1 Topics: 4-Butyrolactone; Animals; Benzodioxoles; Chamaecyparis; Dioxoles; Lignans; Molecular Structure; Nerve Growth Factor; Neurites; PC12 Cells; Plant Leaves; Plants, Medicinal; Rats	2008
Hinokinin biosynthesis in Linum corymbulosum Reichenb. The Plant journal : for cell and molecular biology, 2008, Volume: 55, Issue:5 Topics: 4-Butyrolactone; Amino Acid Sequence; Benzodioxoles; Butylene Glycols; Cells, Cultured; Cloning, Molecular; Dioxoles; DNA, Complementary; Flax; Furans; Gene Expression; Gene Library; Genes, Plant; Lignans; Molecular Sequence Data; Oxidoreductases; Phylogeny; Plant Proteins; RNA, Plant; Sequence Alignment; Sequence Homology, Amino Acid	2008
Chemical constituents of Aristolochia constricta: antispasmodic effects of its constituents in guinea-pig ileum and isolation of a diterpeno-lignan hybrid. Journal of natural products, 2008, Volume: 71, Issue:7 Topics: 4-Butyrolactone; Animals; Aristolochia; Benzodioxoles; Dioxoles; Diterpenes; Ecuador; Guinea Pigs; Ileum; Lignans; Medicine, Traditional; Parasympatholytics; Plants, Medicinal; Stereoisomerism	2008
Amides and benzenoids from Zanthoxylum ailanthoides with inhibitory activity on superoxide generation and elastase release by neutrophils. Journal of natural products, 2009, Volume: 72, Issue:1 Topics: 4-Butyrolactone; Amides; Benzamides; Benzene Derivatives; Benzodioxoles; Coumarins; Dioxoles; Humans; Inhibitory Concentration 50; Lignans; Molecular Structure; Neutrophils; Pancreatic Elastase; Plant Bark; Plants, Medicinal; Superoxides; Taiwan; Zanthoxylum	2009
[Studies on chemical constituents of rhizome of Buddleia davidii]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2009, Volume: 32, Issue:4 Topics: 4-Butyrolactone; Benzodioxoles; Buddleja; Chromatography, High Pressure Liquid; Dioxoles; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Roots; Plants, Medicinal; Sesquiterpenes; Steroids	2009
(-)-Hinokinin-loaded poly(D,-lactide-co-glycolide) microparticles for Chagas disease. Parasitology research, 2010, Volume: 106, Issue:3 Topics: 4-Butyrolactone; Animals; Antiprotozoal Agents; Benzodioxoles; Chagas Disease; Delayed-Action Preparations; Dioxanes; Dioxoles; Disease Models, Animal; Humans; Lactic Acid; Lignans; Mice; Microspheres; Parasitemia; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome; Trypanosoma cruzi	2010
Reduction of parasitism tissue by treatment of mice chronically infected with Trypanosoma cruzi with lignano lactones. Parasitology research, 2010, Volume: 107, Issue:3 Topics: 4-Butyrolactone; Animals; Benzodioxoles; beta-Galactosidase; Chagas Disease; Chronic Disease; Dioxoles; Heart; Karyometry; Lactones; Lignans; Liver; Mice; Mice, Inbred BALB C; Spleen; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi	2010
Effect of the dibenzylbutyrolactone lignan (-)-hinokinin on doxorubicin and methyl methanesulfonate clastogenicity in V79 Chinese hamster lung fibroblasts. Mutation research, 2010, Jul-19, Volume: 700, Issue:1-2 Topics: 4-Butyrolactone; Animals; Benzodioxoles; Cell Line; Cricetinae; Cricetulus; Dioxoles; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Fibroblasts; Lignans; Lung; Methyl Methanesulfonate; Micronucleus Tests; Mutagens	2010
Dibenzylbutane- and butyrolactone-type lignans as apoptosis inducers in human hepatoma HuH-7 cells. Phytotherapy research : PTR, 2012, Volume: 26, Issue:5 Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; Benzodioxoles; Caspase 3; Cell Line, Tumor; Cell Survival; Dioxoles; Humans; L-Lactate Dehydrogenase; Lactones; Lignans; Myristicaceae; Plant Extracts; Plants, Medicinal	2012
In vivo infection by Trypanosoma cruzi: a morphometric study of tissue changes in mice. Parasitology research, 2013, Volume: 112, Issue:1 Topics: 4-Butyrolactone; Animals; Antiprotozoal Agents; Benzodioxoles; Biometry; Cell Line; Chagas Disease; Dioxoles; Disease Models, Animal; Fibroblasts; Karyotyping; Lignans; Liver; Macaca mulatta; Male; Mice; Mice, Inbred BALB C; Spleen; Trypanosoma cruzi	2013
Mutagenicity and antimutagenicity of (-)-hinokinin a trypanosomicidal compound measured by Salmonella microsome and comet assays. BMC complementary and alternative medicine, 2012, Oct-31, Volume: 12 Topics: 4-Butyrolactone; Animals; Antimutagenic Agents; Benzodioxoles; Cell Line; Chagas Disease; Comet Assay; Cricetinae; Dioxoles; DNA Damage; Humans; Lignans; Mutagens; Piper; Plant Extracts; Salmonella; Seeds; Trypanocidal Agents	2012
Evaluation of the in vivo therapeutic properties of (-)-cubebin and (-)-hinokinin against Trypanosoma cruzi. Experimental parasitology, 2013, Volume: 133, Issue:4 Topics: 4-Butyrolactone; Animals; Benzodioxoles; Chagas Disease; Dioxoles; Lignans; Male; Mice; Mice, Inbred BALB C; Nitroimidazoles; Piper; Trypanocidal Agents; Trypanosoma cruzi	2013
Isolation of anti-tumor compounds from the stem bark of Zanthoxylum ailanthoides Sieb. & Zucc. by silica gel column and counter-current chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Jun-15, Volume: 929 Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Benzodioxoles; Cell Line, Tumor; Cell Survival; Coumarins; Countercurrent Distribution; Dioxoles; Humans; Lignans; Plant Bark; Silica Gel; Zanthoxylum	2013
The lignan (-)-hinokinin displays modulatory effects on human monoamine and GABA transporter activities. Journal of natural products, 2013, Oct-25, Volume: 76, Issue:10 Topics: 4-Butyrolactone; Attention Deficit Disorder with Hyperactivity; Benzodioxoles; Dioxoles; Dopamine; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; Humans; Lignans; Molecular Structure; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism	2013
Isolation, structural elucidation and anti-inflammatory activity of astragalin, (-)hinokinin, aristolactam I and aristolochic acids (I & II) from Aristolochia indica. Natural product research, 2014, Volume: 28, Issue:17 Topics: 4-Butyrolactone; Anti-Inflammatory Agents; Aristolochia; Aristolochic Acids; Benzodioxoles; Chromatography, High Pressure Liquid; Dioxoles; Interleukin-6; Kaempferols; Lignans	2014
Chemopreventive effects of (-)-hinokinin against 1,2-dimethylhydrazine-induced genotoxicity and preneoplastic lesions in rat colon. Journal of natural products, 2014, Oct-24, Volume: 77, Issue:10 Topics: 1,2-Dimethylhydrazine; 4-Butyrolactone; Animals; Anticarcinogenic Agents; Benzodioxoles; Carcinogens; Colon; Comet Assay; Dimethylhydrazines; Dioxoles; DNA Damage; Lignans; Male; Molecular Structure; Piper; Rats; Rats, Wistar; Stereoisomerism	2014
Concentration of hinokinin, phenolic acids and flavonols in leaves and stems of Hydrocotyle leucocephala is differently influenced by PAR and ecologically relevant UV-B level. Journal of plant physiology, 2015, Jan-15, Volume: 173 Topics: 4-Butyrolactone; Benzodioxoles; Centella; Chlorogenic Acid; Flavonols; Hydroxybenzoates; Kaempferols; Lignans; Oxidative Stress; Photosynthesis; Plant Leaves; Plant Stems; Propanols; Quercetin; Ultraviolet Rays	2015
Antileukemic activity of lignans and phenylpropanoids of Cinnamomum parthenoxylon. Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3 Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Benzodioxoles; Cell Proliferation; Cinnamomum; HL-60 Cells; Humans; Lignans; Plant Extracts; U937 Cells	2016
(-)-Hinokinin Induces G2/M Arrest and Contributes to the Antiproliferative Effects of Doxorubicin in Breast Cancer Cells. Planta medica, 2016, Volume: 82, Issue:6 Topics: 4-Butyrolactone; Antineoplastic Combined Chemotherapy Protocols; Benzodioxoles; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Lignans; M Phase Cell Cycle Checkpoints	2016
In vivo and in silico anti-inflammatory mechanism of action of the semisynthetic (-)-cubebin derivatives (-)-hinokinin and (-)-O-benzylcubebin. Bioorganic & medicinal chemistry letters, 2017, 01-15, Volume: 27, Issue:2 Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzodioxoles; Catalytic Domain; Computer Simulation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyproheptadine; Dextrans; Dinoprostone; Dioxoles; Edema; Furans; Indomethacin; Ligands; Lignans; Male; Mice; Molecular Docking Simulation; Polysorbates; Rats, Wistar; Rutaceae	2017
COX Inhibition Profiles and Molecular Docking Studies of the Lignan Hinokinin and Some Synthetic Derivatives. Molecular informatics, 2018, Volume: 37, Issue:12 Topics: 4-Butyrolactone; Benzodioxoles; Binding Sites; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Humans; Lactones; Lignans; Meloxicam; Molecular Docking Simulation; Protein Binding; Quantitative Structure-Activity Relationship; Substrate Specificity; Sulfones	2018
Antinociceptive Effect of Hinokinin and Kaurenoic Acid Isolated from Molecules (Basel, Switzerland), 2020, Mar-24, Volume: 25, Issue:6 Topics: 4-Butyrolactone; Analgesics; Animals; Aristolochia; Benzodioxoles; Chromatography, High Pressure Liquid; Diterpenes; Lignans; Magnetic Resonance Spectroscopy; Male; Mice; Pain; Pain Measurement; Plant Extracts	2020
Hinokinin alleviates high fat diet/streptozotocin-induced cardiac injury in mice through modulation in oxidative stress, inflammation and apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 137 Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Benzodioxoles; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Diet, High-Fat; Dyslipidemias; Hyperglycemia; Lignans; Mice; Oxidative Stress; Signal Transduction; Streptozocin	2021
Optimization of (-)-cubebin biotransformation to (-)-hinokinin by the marine fungus Absidia coerulea 3A9. Archives of microbiology, 2021, Volume: 203, Issue:7 Topics: 4-Butyrolactone; Absidia; Aquatic Organisms; Benzodioxoles; Biotransformation; Lignans; Seawater	2021
Natural product research, 2022, Volume: 36, Issue:18 Topics: 4-Butyrolactone; Antineoplastic Agents; Benzodioxoles; Lactic Acid; Lignans; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer	2022
Total Synthesis of Polysubstituted γ-Butyrolactone Lignans (-)-Hinokinin, (-)-Bicubebin B, and (-)-Isodeoxypodophyllotoxin via Oxime Carbonate Formation. Organic letters, 2023, 01-13, Volume: 25, Issue:1 Topics: 4-Butyrolactone; Biological Products; Lignans	2023