Compounds > 4-butyrolactone
Page last updated: 2024-08-18

4-butyrolactone and glucose, (beta-d)-isomer

4-butyrolactone has been researched along with glucose, (beta-d)-isomer in 60 studies

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (10.00)18.2507
2000's22 (36.67)29.6817
2010's27 (45.00)24.3611
2020's5 (8.33)2.80

Authors

AuthorsStudies
Fujimoto, T; Nishibe, S; Nose, M; Ogihara, Y; Takeda, T1
He, H; Li, XL; Zhang, HZ; Zhang, P1
Fujimoto, T; Nishibe, S; Nose, M; Ogihara, Y1
Christensen, LP; Kristiansen, K1
McGovern, TW1
Kitts, DD; Thompson, LU; Wijewickreme, AN; Yuan, YV1
Hattori, M; Li, Y; Meselhy, MR; Qin, GW; Wang, LQ1
Chang, J; Xu, YM; Xuan, LJ; Zhang, JS1
Ren, YL; Yang, JS1
Chang, C; Chen, CC; Hsu, FL; Huang, RL; Huang, YL; Ou, JC1
Hirose, M; Imazawa, T; Iwata, T; Kasai, M; Kitamura, Y; Nishikawa, A; Okazaki, K; Son, HY; Tsutsumi, K; Yamagishi, M; Yamauchi, Y1
Ahn, KS; Jeong, GS; Joung, H; Lee, HK; Lee, SK; Li, G; Min, BS; Na, MK; Oh, SR1
Arts, IC; Hollman, PC; Kuijsten, A; Vree, TB1
Alpert, CA; Blaut, M; Clavel, T; Doré, J; Henderson, G; Philippe, C; Rigottier-Gois, L1
Bügel, S; Hallund, J; Ravn-Haren, G; Tetens, I; Tholstrup, T1
Blaut, M; Clavel, T; Doré, J; Engst, W; Henderson, G1
Boone, MJ; Coiner, HA; Krens, FA; Lunkenbein, S; Salentijn, EM; Schwab, W1
Ju, JH; Yang, JS; Zou, ZJ1
Kwon, SW; Park, JH; Yoo, HH1
Bae, KH; Jang, DS; Kim, JM; Kim, JS; Lee, GY; Lee, YM1
Blaut, M; Clavel, T; Doré, J; Gavini, F; Lippman, R1
Hu, C; Kitts, DD; Yuan, YV1
Akao, T; Hattori, M; Jin, JS; Kakiuchi, N; Min, BS; Nakamura, N; Zhao, YF1
Daimon, T; Fukui, T; Hayashi, T; Imai, Y; Itoh, S; Miyake, M; Oku, T; Sugaya, N; Toyoshima, S; Tsuji, T1
Aydoğmuş, Z; Güven, KC; Topcu, G1
Cao, R; Cui, S; Gagnon, N; Mir, PS; Petit, HV1
Schwab, W; Somoza, V; Stadler, NC1
Bull, JR; Caira, MR; Chibale, K; Stevens, AT1
Mitsuhashi, S; Shigetomi, K; Shoji, K; Ubukata, M1
Ekholm, FS; Eklund, P; Leino, R1
Boldizsár, I; Kraszni, M; Molnár-Perl, I; Noszál, B; Tóth, F1
Ayella, A; Iwamoto, T; Jiang, Y; Lim, S; Lin, D; Tomich, J; Wang, W1
Britten, M; Côrtes, C; Gagnon, N; Giroux, HJ; Matumoto-Pintro, PT; Petit, HV1
Guo, J; Li, L; Meng, F; Sun, L; Yu, N; Zhao, Y1
Amaretti, A; Leonardi, A; Raimondi, S; Roncaglia, L; Rossi, M1
Jaroszewski, JW; Johansen, KT; Nyberg, NT; Wubshet, SG1
Ding, W; Duan, J; Liu, P; Qian, D; Shang, E; Tang, Y; Wu, J1
Bi, CW; Chen, JP; Dong, TT; Du, CY; Lau, DT; Tsim, KW; Zhan, JY; Zhang, WL; Zhao, KJ; Zheng, KY; Zhu, KY1
Debouche, C; During, A; Larondelle, Y; Raas, T1
Dou, DQ; Han, XY; He, F; Kang, TG; Pan, Q; Tan, RQ; Wang, J; Wang, W1
Chen, WM; Shaw, LH; Tsai, TH1
Bastías, JM; Estévez, AM; Figuerola, F; Fuentealba, C; Muñoz, O1
Mitsuhashi, S; Olesen, SH; Schönbrunn, E; Shigetomi, K; Ubukata, M; Yang, Y1
Alcorn, J; Krol, ES; Michel, D; Muir, AD; Mukker, JK1
Ikegami, F; Namiki, T; Saito, Y; Sumino, M1
Hayashi, E; Kato, Y; Kawakami, S; Nomura, T; Ogita, S1
Jan, KC; Liu, TC; Yang, BB1
Alcorn, J; Krol, ES; Muir, AD; Mukker, JK; Singh, RS1
Cheng, X; Su, S; Wink, M1
Back, SY; Bae, MJ; Choi, SW; Do, JR; Jung, SY; Kim, YT; See, HJ; Shin, HS; Shon, DH1
Amaretti, A; García-Villalba, R; Leonardi, A; Quartieri, A; Raimondi, S; Rossi, M; Tomàs-Barberàn, F1
Hu, PY; Liu, D; Tang, Y; Wu, Q; Yang, M; Zheng, Q1
Chen, CY; Chen, LH; Chen, WG; Huang, Y; Qin, LQ; Ren, GY1
Kato, Y; Nomura, T; Ogita, S; Ueno, A1
Bowers, LW; Camp, KK; Fabian, CJ; Ford, NA; Hursting, SD; Kimler, BK; Lineberger, CG; Punjala, A; Rossi, EL1
Dhaini, J; Haykal, T; Hodroj, MH; Rizk, S; Tannous, S1
Feng, X; Liu, L; Ma, CM; Xu, HY; Zhang, G; Zhang, L; Zheng, Z; Zhuang, CC1
Alcorn, J; Guo, Y; Mustafa, R; Purdy, SK; Reaney, MJT; Shen, J; Tse, TJ; Yang, X1
An, H; Bai, X; Guo, S; Kang, X; Li, S; Liu, X; Shi, S1
Luo, J; Sun, L; Wang, P; Xu, Q; Yu, L; Zhang, L; Zheng, Z; Zhou, J; Zuo, D1

Trials

2 trial(s) available for 4-butyrolactone and glucose, (beta-d)-isomer

ArticleYear
A lignan complex isolated from flaxseed does not affect plasma lipid concentrations or antioxidant capacity in healthy postmenopausal women.
    The Journal of nutrition, 2006, Volume: 136, Issue:1

    Topics: 4-Butyrolactone; Butylene Glycols; Cross-Over Studies; Denmark; Double-Blind Method; Female; Flax; Glucosides; Humans; Lignans; Lipids; Middle Aged; Postmenopause

2006
Technical note: Quantification of lignans in the urine, milk, and plasma of flaxseed cake-fed dairy sheep.
    Journal of dairy science, 2021, Volume: 104, Issue:1

    Topics: 4-Butyrolactone; Animal Feed; Animals; Butylene Glycols; Flax; Glucosides; Lignans; Milk; Seeds; Sheep

2021

Other Studies

58 other study(ies) available for 4-butyrolactone and glucose, (beta-d)-isomer

ArticleYear
Structural transformation of lignan compounds in rat gastrointestinal tract.
    Planta medica, 1992, Volume: 58, Issue:6

    Topics: 4-Butyrolactone; Animals; Biotransformation; Furans; Glucosides; Lignans; Lignin; Male; Plants, Medicinal; Rats; Rats, Wistar

1992
[Chemical components of Trachelospelmun jasminoides (Lindl.) Lem. var. heterophyllum Tsiang].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1994, Volume: 19, Issue:4

    Topics: 4-Butyrolactone; Drugs, Chinese Herbal; Glucosides; Stereoisomerism

1994
Structural transformation of lignan compounds in rat gastrointestinal tract; II. Serum concentration of lignans and their metabolites.
    Planta medica, 1993, Volume: 59, Issue:2

    Topics: 4-Butyrolactone; Animals; Digestive System; Drugs, Chinese Herbal; Furans; Glucosides; Lignans; Lignin; Male; Molecular Structure; Rats; Rats, Wistar

1993
Isolation and quantification of tuliposides and tulipalins in tulips (Tulipa) by high-performance liquid chromatography.
    Contact dermatitis, 1999, Volume: 40, Issue:6

    Topics: 4-Butyrolactone; Allergens; Chromatography, High Pressure Liquid; Glucosides; Glycosides; Plants; Sodium Oxybate

1999
Alstroemeria L. (Peruvian lily).
    American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 1999, Volume: 10, Issue:3

    Topics: 4-Butyrolactone; Adult; Allergens; Dermatitis, Allergic Contact; Glucosides; Glycosides; Hand Dermatoses; Humans; Male; Occupational Diseases; Occupational Exposure; Patch Tests; Plant Extracts; Plants; Sodium Oxybate

1999
Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone.
    Molecular and cellular biochemistry, 1999, Volume: 202, Issue:1-2

    Topics: 4-Butyrolactone; Animals; Antioxidants; Butylene Glycols; Emulsions; Estrogens; Flax; Free Radical Scavengers; Glucosides; Hydroxides; Lignans; Linoleic Acid; Lipid Peroxidation; Mammals; Oxidation-Reduction; Seeds

1999
Human intestinal bacteria capable of transforming secoisolariciresinol diglucoside to mammalian lignans, enterodiol and enterolactone.
    Chemical & pharmaceutical bulletin, 2000, Volume: 48, Issue:11

    Topics: 4-Butyrolactone; Animals; Butylene Glycols; Culture Media; Estrogens; Eubacterium; Feces; Glucosides; Humans; Intestines; Lignans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Peptostreptococcus; Rats; Rats, Wistar

2000
Cytotoxic terpenoid and immunosuppressive phenolic glycosides from the root bark of Dictamnus dasycarpus.
    Planta medica, 2002, Volume: 68, Issue:5

    Topics: 4-Butyrolactone; Carbon Isotopes; Disaccharides; Furans; Glucosides; Glycosides; Humans; Immunosuppressive Agents; Lung Neoplasms; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Bark; Plant Roots; Rutaceae; Terpenes; Tumor Cells, Cultured

2002
[Study on chemical constituents of Hemistepta lyrata Bunge].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2001, Volume: 36, Issue:10

    Topics: 4-Butyrolactone; Apigenin; Asteraceae; Flavonoids; Glucosides; Kaempferols; Molecular Structure; Plants, Medicinal

2001
Screening of 25 compounds isolated from Phyllanthus species for anti-human hepatitis B virus in vitro.
    Phytotherapy research : PTR, 2003, Volume: 17, Issue:5

    Topics: 4-Butyrolactone; Anisoles; Benzodioxoles; Culture Techniques; Dioxoles; Enzyme-Linked Immunosorbent Assay; Glucosides; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Hydrolyzable Tannins; Lignans; Molecular Structure; Phyllanthus; Phytotherapy; Plant Extracts; Tannins

2003
Lack of significant inhibitory effects of a plant lignan tracheloside on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in female Sprague-Dawley rats.
    Cancer letters, 2003, Oct-28, Volume: 200, Issue:2

    Topics: 4-Butyrolactone; Animals; Anticarcinogenic Agents; Carcinogens; Female; Glucosides; Imidazoles; Lignans; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley

2003
New furofuran and butyrolactone lignans with antioxidant activity from the stem bark of Styrax japonica.
    Journal of natural products, 2004, Volume: 67, Issue:12

    Topics: 4-Butyrolactone; Antioxidants; Biphenyl Compounds; Furans; Glucosides; Glycosides; Korea; Lignans; Molecular Structure; Oleanolic Acid; Phenylpropionates; Picrates; Plant Bark; Plants, Medicinal; Stereoisomerism; Styrax

2004
Pharmacokinetics of enterolignans in healthy men and women consuming a single dose of secoisolariciresinol diglucoside.
    The Journal of nutrition, 2005, Volume: 135, Issue:4

    Topics: 4-Butyrolactone; Adult; Blood Specimen Collection; Butylene Glycols; Dietary Supplements; Female; Glucosides; Humans; Lignans; Male; Reference Values

2005
Intestinal bacterial communities that produce active estrogen-like compounds enterodiol and enterolactone in humans.
    Applied and environmental microbiology, 2005, Volume: 71, Issue:10

    Topics: 4-Butyrolactone; Actinobacteria; Adult; Bacteria, Anaerobic; Butylene Glycols; Colony Count, Microbial; Culture Media; Female; Flow Cytometry; Glucosides; Humans; In Situ Hybridization, Fluorescence; Intestines; Lignans; Male; Middle Aged; Peptostreptococcus; Phytoestrogens

2005
Phylogeny of human intestinal bacteria that activate the dietary lignan secoisolariciresinol diglucoside.
    FEMS microbiology ecology, 2006, Volume: 55, Issue:3

    Topics: 4-Butyrolactone; Bacteria, Anaerobic; Butylene Glycols; Culture Media; Glucosides; Humans; Intestines; Lignans; Phylogeny

2006
Up- and down-regulation of Fragaria x ananassa O-methyltransferase: impacts on furanone and phenylpropanoid metabolism.
    Journal of experimental botany, 2006, Volume: 57, Issue:10

    Topics: 4-Butyrolactone; Caffeic Acids; Fragaria; Fruit; Furans; Gene Expression; Glucosides; Odorants; Plants, Genetically Modified; Protein O-Methyltransferase; RNA, Messenger

2006
[Studies on the chemical constituents in herbs of Hemistepta lyrata].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:10

    Topics: 4-Butyrolactone; Asteraceae; Caffeic Acids; Glucosides; Plants, Medicinal; Uracil

2006
An anti-estrogenic lignan glycoside, tracheloside, from seeds of Carthamus tinctorius.
    Bioscience, biotechnology, and biochemistry, 2006, Volume: 70, Issue:11

    Topics: 4-Butyrolactone; Carthamus tinctorius; Cell Line; Enzyme Activation; Estrogens; Glucosides; Glycosides; Lignans; Molecular Structure; Plant Extracts; Seeds; Solubility

2006
Constituents of the roots of Pueraria lobata inhibit formation of advanced glycation end products (AGEs).
    Archives of pharmacal research, 2006, Volume: 29, Issue:10

    Topics: 4-Butyrolactone; Dose-Response Relationship, Drug; Glucosides; Glycation End Products, Advanced; Isoflavones; Molecular Structure; Phenols; Plant Extracts; Plant Roots; Pueraria; Spectrum Analysis

2006
Clostridium saccharogumia sp. nov. and Lactonifactor longoviformis gen. nov., sp. nov., two novel human faecal bacteria involved in the conversion of the dietary phytoestrogen secoisolariciresinol diglucoside.
    Systematic and applied microbiology, 2007, Volume: 30, Issue:1

    Topics: 4-Butyrolactone; Adult; Base Composition; Butylene Glycols; Clostridium; Colon; Culture Media; Dietary Carbohydrates; DNA; DNA, Ribosomal; Feces; Genotype; Glucosides; Gram-Positive Rods; Humans; Lignans; Male; Molecular Sequence Data; Nucleic Acid Hybridization; Phenotype; Phylogeny; Phytoestrogens; RNA, Ribosomal, 16S

2007
Antioxidant activities of the flaxseed lignan secoisolariciresinol diglucoside, its aglycone secoisolariciresinol and the mammalian lignans enterodiol and enterolactone in vitro.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:11

    Topics: 4-Butyrolactone; Animals; Biphenyl Compounds; Butylene Glycols; Flax; Free Radical Scavengers; Glucosides; Hydrazines; Lignans; Liposomes; Mammals; Molecular Structure; Picrates; Seeds

2007
Enantioselective dehydroxylation of enterodiol and enterolactone precursors by human intestinal bacteria.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:11

    Topics: 4-Butyrolactone; Bacteria, Anaerobic; Biotransformation; Butylene Glycols; Eubacterium; Feces; Glucosides; Humans; Hydroxylation; Intestines; Lignans; Molecular Structure; Phylogeny; RNA, Bacterial; RNA, Ribosomal, 16S; Stereoisomerism

2007
Exclusion of actin-binding protein p57/coronin-1 from bacteria-containing phagosomes in macrophages infected with Legionella.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:5

    Topics: 4-Butyrolactone; Actins; Bacteria; Carrier Proteins; Cell Line; Cytochalasins; Fluorescent Dyes; Humans; Legionella pneumophila; Legionnaires' Disease; Macrophages; Microfilament Proteins; Microscopy, Confocal; Phagosomes; Xanthenes; Zymosan

2008
Studies on chemical constituents of Gracilaria verrucosa.
    Natural product research, 2008, Volume: 22, Issue:18

    Topics: 4-Butyrolactone; Fatty Acids; Fatty Acids, Monounsaturated; Gas Chromatography-Mass Spectrometry; Glucosides; Gracilaria; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Stigmasterol

2008
Milk concentration of the mammalian lignan enterolactone, milk production, milk fatty acid profile, and digestibility in dairy cows fed diets containing whole flaxseed or flaxseed meal.
    The Journal of dairy research, 2009, Volume: 76, Issue:3

    Topics: 4-Butyrolactone; Animals; Butylene Glycols; Cattle; Diet; Digestion; Fatty Acids; Flax; Glucosides; Lactation; Lignans; Male; Milk; Seeds

2009
Absorption of 3(2H)-furanones by human intestinal epithelial Caco-2 cells.
    Journal of agricultural and food chemistry, 2009, May-13, Volume: 57, Issue:9

    Topics: 4-Butyrolactone; Biological Transport; Caco-2 Cells; Diffusion; Epithelium; Furans; Glucosides; Humans; Hydrolysis; Intestinal Absorption; Kinetics; Osmolar Concentration

2009
Cycloaddition and one-carbon homologation studies in the synthesis of advanced iridoid precursors.
    Organic & biomolecular chemistry, 2009, Sep-07, Volume: 7, Issue:17

    Topics: 4-Butyrolactone; Carbon; Crystallography, X-Ray; Glucosides; Iridoid Glucosides; Iridoids; Molecular Conformation; Organic Chemistry Phenomena

2009
The antibacterial properties of 6-tuliposide B. Synthesis of 6-tuliposide B analogues and structure-activity relationship.
    Phytochemistry, 2010, Volume: 71, Issue:2-3

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Bacteria; Flowers; Glucosides; Glycosides; Hydroxybutyrates; Microbial Sensitivity Tests; Molecular Structure; Plant Extracts; Structure-Activity Relationship; Tulipa

2010
A short semi-synthesis and complete NMR-spectroscopic characterization of the naturally occurring lignan glycoside matairesinol 4,4'-di-O-beta-D-diglucoside.
    Carbohydrate research, 2010, Sep-03, Volume: 345, Issue:13

    Topics: 4-Butyrolactone; Apocynaceae; Biological Products; Glucosides; Lignans; Magnetic Resonance Spectroscopy; Plant Stems; Stereoisomerism

2010
Complementary fragmentation pattern analysis by gas chromatography-mass spectrometry and liquid chromatography tandem mass spectrometry confirmed the precious lignan content of Cirsium weeds.
    Journal of chromatography. A, 2010, Oct-01, Volume: 1217, Issue:40

    Topics: 4-Butyrolactone; Chromatography, Liquid; Cirsium; Fruit; Gas Chromatography-Mass Spectrometry; Glucosides; Lignans; Nuclear Magnetic Resonance, Biomolecular; Oximes; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Trimethylsilyl Compounds

2010
Cytostatic inhibition of cancer cell growth by lignan secoisolariciresinol diglucoside.
    Nutrition research (New York, N.Y.), 2010, Volume: 30, Issue:11

    Topics: 4-Butyrolactone; Adenocarcinoma; Anticarcinogenic Agents; Butylene Glycols; Cell Cycle; Cell Line, Tumor; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cyclin A; Cytostatic Agents; Dietary Carbohydrates; Dose-Response Relationship, Drug; Glucosides; Glycosides; Humans; Lignans; Mass Spectrometry

2010
Effect of flaxseed lignans added to milk or fed to cows on oxidative degradation of dairy beverages enriched with polyunsaturated fatty acids.
    The Journal of dairy research, 2011, Volume: 78, Issue:1

    Topics: 4-Butyrolactone; Animals; Antioxidants; Butylene Glycols; Cattle; Diet; Fatty Acids, Unsaturated; Female; Flax; Food, Fortified; Glucosides; Hot Temperature; Lignans; Milk; Oxidation-Reduction; Oxidative Stress; Photochemical Processes

2011
Simultaneous quantification of tracheloside and trachelogenin in rat plasma using liquid chromatography/tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, May-01, Volume: 879, Issue:15-16

    Topics: 4-Butyrolactone; Analysis of Variance; Animals; Apocynaceae; Chromatography, Liquid; Female; Glucosides; Linear Models; Male; Plant Stems; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2011
Role of bifidobacteria in the activation of the lignan secoisolariciresinol diglucoside.
    Applied microbiology and biotechnology, 2011, Volume: 92, Issue:1

    Topics: 4-Butyrolactone; Bifidobacterium; Biotransformation; Butylene Glycols; Glucosides; Lignans

2011
From retrospective assessment to prospective decisions in natural product isolation: HPLC-SPE-NMR analysis of Carthamus oxyacantha.
    Journal of natural products, 2011, Nov-28, Volume: 74, Issue:11

    Topics: 4-Butyrolactone; Biological Products; Carthamus; Chromatography, High Pressure Liquid; Glucosides; Iran; Magnetic Resonance Spectroscopy; Molecular Structure; Plants, Medicinal; Spiro Compounds

2011
[Influence of different solutions on extracting of active components in Danggui Chishao drug pair].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:7

    Topics: 4-Butyrolactone; Benzoates; Benzofurans; Bridged-Ring Compounds; Chromatography, Liquid; Drugs, Chinese Herbal; Gallic Acid; Glucosides; Hydroxybenzoates; Mass Spectrometry; Monoterpenes; Phthalic Acids; Solvents; Vanillic Acid

2012
Chemical and biological assessment of Angelica herbal decoction: comparison of different preparations during historical applications.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Aug-15, Volume: 19, Issue:11

    Topics: 4-Butyrolactone; Angelica; Animals; Astragalus propinquus; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Coumaric Acids; Drugs, Chinese Herbal; Erythropoiesis; Female; Glucosides; Humans; Isoflavones; Medicine, Chinese Traditional; Osteogenesis; Plant Roots; Promoter Regions, Genetic; Receptors, Estrogen; Saponins; Triterpenes

2012
Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells.
    The Journal of nutrition, 2012, Volume: 142, Issue:10

    Topics: 4-Butyrolactone; Anti-Inflammatory Agents; Butylene Glycols; Caco-2 Cells; Cell Differentiation; Chemokine CCL2; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Furans; Glucosides; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; Intestines; Lignans; NF-kappa B; Plant Extracts; Signal Transduction

2012
Simultaneous determination of arctiin and its metabolites in rat urine and feces by HPLC.
    Fitoterapia, 2013, Volume: 86

    Topics: 4-Butyrolactone; Animals; Arctium; Chromatography, High Pressure Liquid; Feces; Fruit; Furans; Glucosides; Lignans; Male; Plant Extracts; Rats, Sprague-Dawley

2013
Identification of multiple ingredients for a Traditional Chinese Medicine preparation (bu-yang-huan-wu-tang) by liquid chromatography coupled with tandem mass spectrometry.
    Molecules (Basel, Switzerland), 2013, Sep-12, Volume: 18, Issue:9

    Topics: 4-Butyrolactone; Benzoates; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Digoxin; Drugs, Chinese Herbal; Glucosides; Humans; Isoflavones; Limit of Detection; Medicine, Chinese Traditional; Monoterpenes; Reproducibility of Results; Saponins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triterpenes

2013
Bioaccessibility of lignans from flaxseed (Linum usitatissimum L.) determined by single-batch in vitro simulation of the digestive process.
    Journal of the science of food and agriculture, 2014, Volume: 94, Issue:9

    Topics: 4-Butyrolactone; Bacteria, Anaerobic; Biological Availability; Butylene Glycols; Colon; Fatty Acids, Volatile; Fermentation; Flax; Glucosides; Humans; In Vitro Techniques; Lignans; Seeds

2014
MurA as a primary target of tulipalin B and 6-tuliposide B.
    Bioscience, biotechnology, and biochemistry, 2013, Volume: 77, Issue:12

    Topics: 4-Butyrolactone; Alkyl and Aryl Transferases; Enzyme Inhibitors; Escherichia coli; Glucosides; Hydroxybutyrates

2013
Permeability and conjugative metabolism of flaxseed lignans by Caco-2 human intestinal cells.
    Journal of natural products, 2014, Jan-24, Volume: 77, Issue:1

    Topics: 4-Butyrolactone; Algorithms; Butylene Glycols; Caco-2 Cells; Chromatography, High Pressure Liquid; Flax; Glucosides; Humans; Intestinal Mucosa; Lignans; Molecular Structure; Permeability

2014
A simultaneous determination of principal compounds in tokishakuyakusan by high-performance liquid chromatography with diode array detector.
    Journal of chromatographic science, 2015, Volume: 53, Issue:2

    Topics: 4-Butyrolactone; Cholestenones; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Glucosides; Lactones; Limit of Detection; Linear Models; Monoterpenes; Reproducibility of Results; Sesquiterpenes

2015
Environmentally benign process for the preparation of antimicrobial α-methylene-β-hydroxy-γ-butyrolactone (tulipalin B) from tulip biomass.
    Bioscience, biotechnology, and biochemistry, 2015, Volume: 79, Issue:1

    Topics: 4-Butyrolactone; Anti-Infective Agents; Biomass; Carboxylic Ester Hydrolases; Charcoal; Enzymes, Immobilized; Ethanol; Flowers; Glucosides; Green Chemistry Technology; Hydroxybutyrates; Plant Extracts; Plant Proteins; Tulipa

2015
Gene expression profiling of sesaminol triglucoside and its tetrahydrofuranoid metabolites in primary rat hepatocytes.
    International journal of food sciences and nutrition, 2014, Volume: 65, Issue:8

    Topics: 4-Butyrolactone; Animals; ATP-Binding Cassette Transporters; Cytochrome P-450 Enzyme System; Dioxoles; Furans; Gene Expression; Gene Expression Profiling; Glucosides; Hepatocytes; Inactivation, Metabolic; Lignans; Liver; Mammals; Plant Extracts; Rats, Sprague-Dawley; Seeds; Sesamum

2014
Comparative pharmacokinetics of purified flaxseed and associated mammalian lignans in male Wistar rats.
    The British journal of nutrition, 2015, Mar-14, Volume: 113, Issue:5

    Topics: 4-Butyrolactone; Administration, Oral; Animals; Biological Availability; Butylene Glycols; Dietary Supplements; Dose-Response Relationship, Drug; Estrogens; Flax; Glucosides; Half-Life; Injections, Intravenous; Intestinal Absorption; Kinetics; Lignans; Male; Metabolic Clearance Rate; Phytoestrogens; Random Allocation; Rats, Wistar; Seeds

2015
Natural lignans from Arctium lappa modulate P-glycoprotein efflux function in multidrug resistant cancer cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, Feb-15, Volume: 22, Issue:2

    Topics: 4-Butyrolactone; Antineoplastic Agents; Arctium; ATP Binding Cassette Transporter, Subfamily B; Benzofurans; Caco-2 Cells; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Furans; Glucosides; Humans; Lignans; Molecular Structure; Rhodamine 123; Seeds

2015
Enhancing Effect of Trachelogenin from Trachelospermi caulis Extract on Intestinal Barrier Function.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:11

    Topics: 4-Butyrolactone; Allergens; Apocynaceae; Caco-2 Cells; Colon; Food Hypersensitivity; Glucosides; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Occludin; Ovalbumin; Permeability; Phytotherapy; Plant Extracts; Tight Junctions

2015
Detection of novel metabolites of flaxseed lignans in vitro and in vivo.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:7

    Topics: 4-Butyrolactone; Adult; Bifidobacterium pseudocatenulatum; Butylene Glycols; Dietary Supplements; Feces; Female; Flax; Furans; Gastrointestinal Microbiome; Glucosides; Humans; Intestinal Mucosa; Intestines; Lignans; Male; Middle Aged; Prebiotics; Probiotics; Young Adult

2016
Elucidation of Transport Mechanism of Paeoniflorin and the Influence of Ligustilide, Senkyunolide I and Senkyunolide A on Paeoniflorin Transport through Mdck-Mdr1 Cells as Blood-Brain Barrier in Vitro Model.
    Molecules (Basel, Switzerland), 2016, Mar-02, Volume: 21, Issue:3

    Topics: 4-Butyrolactone; Animals; ATP Binding Cassette Transporter, Subfamily B; Benzofurans; Biological Transport; Blood-Brain Barrier; Dogs; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucosides; Humans; In Vitro Techniques; Madin Darby Canine Kidney Cells; Molecular Structure; Monoterpenes

2016
The treatment effects of flaxseed-derived secoisolariciresinol diglycoside and its metabolite enterolactone on benign prostatic hyperplasia involve the G protein-coupled estrogen receptor 1.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2016, Volume: 41, Issue:12

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Binding Sites; Butylene Glycols; Cell Line, Tumor; Cell Proliferation; Dietary Supplements; Flax; Gene Expression Regulation, Neoplastic; Glucosides; Glycosides; Humans; Lignans; Male; Models, Molecular; Molecular Docking Simulation; Neoplasm Proteins; Prostate; Prostatic Hyperplasia; Random Allocation; Rats; Rats, Wistar; Receptors, Estrogen; Receptors, G-Protein-Coupled; RNA Interference; Seeds

2016
Molecular diversity of tuliposide B-converting enzyme in tulip (Tulipa gesneriana): identification of the root-specific isozyme.
    Bioscience, biotechnology, and biochemistry, 2017, Volume: 81, Issue:6

    Topics: 4-Butyrolactone; Amino Acid Sequence; Anti-Infective Agents; Biotransformation; Carboxylic Ester Hydrolases; Cloning, Molecular; Escherichia coli; Gene Expression; Gene Expression Regulation, Plant; Glucosides; Hydroxybutyrates; Isoenzymes; Kinetics; Organ Specificity; Plant Proteins; Plant Roots; Pollen; Recombinant Proteins; Secondary Metabolism; Substrate Specificity; Transcription, Genetic; Tulipa

2017
The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth.
    Breast cancer research and treatment, 2019, Volume: 173, Issue:3

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Biomarkers; Butylene Glycols; Cell Line, Tumor; Cell Survival; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Flax; Gene Expression Profiling; Glucosides; Immunohistochemistry; Lignans; Mammary Neoplasms, Animal; Mice; NF-kappa B; Signal Transduction

2019
The anti-cancer effect of flaxseed lignan derivatives on different acute myeloid leukemia cancer cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 132

    Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Apoptosis; Butylene Glycols; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Child; Female; Flax; Glucosides; Humans; Leukemia, Myeloid, Acute; Lignans; Plant Extracts; Reactive Oxygen Species; Seeds

2020
Oral Pharmacokinetics of Enriched Secoisolariciresinol Diglucoside and Its Polymer in Rats.
    Journal of natural products, 2021, 06-25, Volume: 84, Issue:6

    Topics: 4-Butyrolactone; Animals; Biological Availability; Butylene Glycols; Female; Flax; Glucosides; Lignans; Molecular Structure; Polymers; Rats; Rats, Wistar; Seeds

2021
Multi-target tracheloside and doxorubicin combined treatment of lung adenocarcinoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: 4-Butyrolactone; Adenocarcinoma of Lung; Apoptosis; Cell Line, Tumor; Doxorubicin; Glucosides; Humans; Lung Neoplasms; Molecular Docking Simulation

2022
Secoisolariciresinol diglucoside-derived metabolite, enterolactone, attenuates atopic dermatitis by suppressing Th2 immune response.
    International immunopharmacology, 2022, Volume: 111

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Butylene Glycols; Child, Preschool; Dermatitis, Atopic; Dinitrochlorobenzene; Glucosides; Humans; Immunity; Lignans; Mice; Mice, Inbred BALB C; Skin

2022