4-butyrolactone has been researched along with cerulenin in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 10 (71.43) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ando, N; Beppu, T; Horinouchi, S; Matsumori, N; Sakuda, S | 1 |
| Bycroft, BW; Camara, M; Chhabra, SR; Hardie, KR; Jiang, Y; Lazdunski, A; Salmond, GP; Stewart, GS; Williams, P | 1 |
| Gabrielson, EW; Kuhajda, FP; Pinn, ML; Testa, JR | 1 |
| Makimura, H; Mobbs, CV | 1 |
| Hirsch, J | 1 |
| Colomer, R; Lupu, R; Mehmi, I; Menendez, JA; Oza, BP; Ropero, S; Vellon, L | 1 |
| Lupu, R; Mehmi, I; Menendez, JA; Teng, PK; Verma, VA | 1 |
| Hamilton, BS; Rippmann, JF; Schmid, B; Tadayyon, M | 1 |
| Kim, EK; Landree, LE; Ronnett, GV; Tu, Y | 1 |
| Henke, A; Jarasch, N; Lottspeich, F; Munder, T; Rassmann, A; Saluz, HP | 1 |
| Chi-Ming Chiu, L; Eng-Choon Ooi, V; Ho, TS; Ho, YP; Wong, WY; Wong, YS | 1 |
| Downs, SM; Klinger, J; Mosey, JL | 1 |
| Ali, SF; Binienda, ZK; Gough, B; Kim, CS; Riccio, T; Ross, IA | 1 |
| Dünisch, P; Ewald, C; Freitag, D; Grube, S; Kalff, R; Klausnitzer, M; Sakr, Y; Walter, J | 1 |
1 review(s) available for 4-butyrolactone and cerulenin
| Article | Year |
|---|---|
Fatty acid metabolism as a target for obesity treatment.
Topics: 4-Butyrolactone; Animals; Body Weight; Carnitine O-Palmitoyltransferase; Cerulenin; Eating; Energy Metabolism; Fatty Acid Synthases; Fatty Acids; Gene Expression; Humans; Models, Biological; Obesity | 2005 |
13 other study(ies) available for 4-butyrolactone and cerulenin
| Article | Year |
|---|---|
Involvement of afsA in A-factor biosynthesis as a key enzyme.
Topics: 4-Butyrolactone; Bacterial Proteins; Cerulenin; Chromatography, High Pressure Liquid; Escherichia coli; Fatty Acids; Growth Substances; Models, Biological; Mutation; Recombinant Proteins; Streptomyces griseus; Streptomycin | 1997 |
In vitro biosynthesis of the Pseudomonas aeruginosa quorum-sensing signal molecule N-butanoyl-L-homoserine lactone.
Topics: 4-Butyrolactone; Acetyl Coenzyme A; Bacterial Proteins; Cerulenin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Kinetics; Ligases; Mass Spectrometry; Pseudomonas aeruginosa; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity; Transcription Factors | 1998 |
Increased fatty acid synthase is a therapeutic target in mesothelioma.
Topics: 4-Butyrolactone; Animals; Antifungal Agents; Antineoplastic Agents; Cerulenin; Disease Models, Animal; Fatty Acid Synthases; Humans; Immunoenzyme Techniques; Mesothelioma; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Mesothelial; Paraffin Embedding; Prognosis; Tumor Cells, Cultured | 2001 |
Block the FAS, lose the fat.
Topics: 4-Butyrolactone; Animals; Anti-Obesity Agents; Cerulenin; Enzyme Inhibitors; Fatty Acid Synthases; Humans; Hypothalamus; Mice; Mice, Obese; Models, Biological; Obesity | 2002 |
The search for new ways to treat obesity.
Topics: 4-Butyrolactone; Adipose Tissue; Animals; Carnitine O-Palmitoyltransferase; Cell Size; Cerulenin; Energy Intake; Fatty Acids; Ghrelin; Humans; Malonyl Coenzyme A; Obesity; Peptide Hormones; Peptides | 2002 |
Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells.
Topics: 4-Butyrolactone; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Line; Cell Size; Cell Survival; Cerulenin; Fatty Acid Synthases; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Humans; Ovarian Neoplasms; Receptor, ErbB-2; RNA, Small Interfering; Signal Transduction; Transcription Factors; Trastuzumab | 2004 |
Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/neu (erbB-2) oncogene-induced malignant transformation.
Topics: 4-Butyrolactone; Animals; Antifungal Agents; Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; Cerulenin; Chemoprevention; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; fas Receptor; Fatty Acid Synthases; Fatty Acids; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Mice; Mitogen-Activated Protein Kinases; NIH 3T3 Cells; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Receptors, Tumor Necrosis Factor | 2004 |
Inhibition of fatty acid synthase prevents preadipocyte differentiation.
Topics: 3T3-L1 Cells; 4-Butyrolactone; Adipocytes; Animals; Cell Differentiation; Cerulenin; Fatty Acid Synthases; Gene Silencing; Mice; Triclosan | 2005 |
The human fatty acid synthase: a new therapeutic target for coxsackievirus B3-induced diseases?
Topics: 4-Butyrolactone; Amino Acid Sequence; Antiviral Agents; Cell Line; Cerulenin; Electrophoresis, Gel, Two-Dimensional; Enterovirus B, Human; Enzyme Inhibitors; Fatty Acid Synthases; Humans; Molecular Sequence Data; Up-Regulation; Virus Replication | 2007 |
Fatty acid synthase inhibitors cerulenin and C75 retard growth and induce caspase-dependent apoptosis in human melanoma A-375 cells.
Topics: 4-Butyrolactone; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspases; Cell Cycle; Cell Line, Tumor; Cerulenin; DNA, Neoplasm; Enzyme Inhibitors; fas Receptor; Fatty Acid Synthases; Flow Cytometry; Genes, bcl-2; Humans; Melanoma; Microscopy, Confocal; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles | 2007 |
Fatty acid oxidation and meiotic resumption in mouse oocytes.
Topics: 4-Butyrolactone; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cerulenin; Cumulus Cells; Epoxy Compounds; Fatty Acids; Female; Malonyl Coenzyme A; Meiosis; Mice; Mice, Inbred C57BL; Oocytes; Oxidation-Reduction; Palmitic Acid; Ribonucleotides | 2009 |
Striatal dopamine in the response of brain and liver unsaturated and saturated free fatty acids following administration of C75 in CD-1 mice.
Topics: 4-Butyrolactone; Animals; Anti-Obesity Agents; Biogenic Monoamines; Brain; Cerulenin; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Eating; Fatty Acids, Monounsaturated; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Liver; Male; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Serotonin; Time Factors | 2010 |
Overexpression of fatty acid synthase in human gliomas correlates with the WHO tumor grade and inhibition with Orlistat reduces cell viability and triggers apoptosis.
Topics: 4-Butyrolactone; Apoptosis; Autophagy; Brain; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Cerulenin; Dose-Response Relationship, Drug; Fatty Acid Synthase, Type I; Fatty Acid Synthesis Inhibitors; Glioblastoma; Glioma; Humans; Lactones; Neoplasm Grading; Orlistat; Tissue Culture Techniques | 2014 |