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4-butyrolactone and cacospongionolide b

4-butyrolactone has been researched along with cacospongionolide b in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's4 (44.44)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crispino, A; De Giulio, A; De Rosa, S; Iodice, C; Pronzato, R; Zavodnik, N1
Alcaraz, MJ; De Rosa, M; Giordano, S; Pastor, PG; Payá, M; Scettri, A; Sodano, G; Soriente, A1
Alcaraz, MJ; De Giulio, A; De Rosa, S; García Pastor, P; Payá, M1
Amodeo, P; Crispino, A; De Giulio, A; De Rosa, S; Iodice, C; Tancredi, T1
Cheung, AK; Snapper, ML1
Alcaraz, MJ; De Rosa, S; Payá, M; Posadas, I; Terencio, MC1
Cheung, AK; Murelli, R; Snapper, ML1
Cheung, AK; Murelli, RP; Snapper, ML1
Carnuccio, R; De Rosa, S; De Stefano, D; Iodice, C; Maiuri, MC; Malik, SA; Tommonaro, G1

Other Studies

9 other study(ies) available for 4-butyrolactone and cacospongionolide b

ArticleYear
Cacospongionolide B, a new sesterterpene from the sponge Fasciospongia cavernosa.
    Journal of natural products, 1995, Volume: 58, Issue:11

    Topics: 4-Butyrolactone; Acetylation; Animals; Anti-Bacterial Agents; Artemia; Cyprinodontiformes; Gram-Negative Bacteria; Gram-Positive Bacteria; Lethal Dose 50; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Porifera; Pyrans

1995
Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues.
    Journal of medicinal chemistry, 1998, Aug-13, Volume: 41, Issue:17

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bee Venoms; Carrageenan; Cell Line; Cytosol; Drug Design; Edema; Elapid Venoms; Enzyme Inhibitors; Female; Humans; Kinetics; Mice; Molecular Structure; Pancreas; Phospholipases A; Phospholipases A2; Pyrans; Structure-Activity Relationship; Swine; Synovial Membrane; Terpenes

1998
Modulation of acute and chronic inflammatory processes by cacospongionolide B, a novel inhibitor of human synovial phospholipase A2.
    British journal of pharmacology, 1999, Volume: 126, Issue:1

    Topics: 4-Butyrolactone; Acute Disease; Animals; Anti-Infective Agents; Arthritis, Experimental; Chronic Disease; Dose-Response Relationship, Drug; Ear; Edema; Enzymes; Female; Humans; Inflammation; Leukocytes; Male; Mice; Phospholipases A; Phospholipases A2; Pyrans; Rats; Rats, Wistar; Synovial Fluid; U937 Cells

1999
A new cacospongionolide derivative from the sponge Fasciospongia cavernosa.
    Journal of natural products, 1999, Volume: 62, Issue:9

    Topics: 4-Butyrolactone; Animals; Anti-Infective Agents; Microbial Sensitivity Tests; Molecular Structure; Porifera; Pyrans; Spectrum Analysis

1999
Total syntheses of (+)- and (-)-cacospongionolide B: new insight into structural requirements for phospholipase A(2) inhibition.
    Journal of the American Chemical Society, 2002, Oct-02, Volume: 124, Issue:39

    Topics: 4-Butyrolactone; Enzyme Inhibitors; Phospholipases A; Pyrans; Stereoisomerism

2002
Cacospongionolide B suppresses the expression of inflammatory enzymes and tumour necrosis factor-alpha by inhibiting nuclear factor-kappa B activation.
    British journal of pharmacology, 2003, Volume: 138, Issue:8

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Female; Gene Expression Regulation, Enzymologic; Mice; NF-kappa B; Porifera; Pyrans; Tumor Necrosis Factor-alpha

2003
Total syntheses of (+)- and (-)-cacospongionolide B, cacospongionolide e, and related analogues. Preliminary study of structural features required for phospholipase a2 inhibition.
    The Journal of organic chemistry, 2004, Aug-20, Volume: 69, Issue:17

    Topics: 4-Butyrolactone; Animals; Enzyme Inhibitors; Molecular Structure; Phospholipases A; Phospholipases A2; Porifera; Pyrans; Stereoisomerism; Structure-Activity Relationship

2004
Conformationally restricted (+)-cacospongionolide B analogues. Influence on secretory phospholipase A2 inhibition.
    The Journal of organic chemistry, 2007, Mar-02, Volume: 72, Issue:5

    Topics: 4-Butyrolactone; Animals; Bee Venoms; Enzyme Inhibitors; Furaldehyde; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Phospholipases A; Phospholipases A2; Porifera; Pyrans; Recombinant Proteins

2007
Cacospongionolide and scalaradial, two marine sesterterpenoids as potent apoptosis-inducing factors in human carcinoma cell lines.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: 4-Butyrolactone; Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Aquatic Organisms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; DNA Fragmentation; Homosteroids; Humans; NF-kappa B p50 Subunit; Porifera; Pyrans; Sesterterpenes; Transcription Factor RelA

2012