Page last updated: 2024-08-18

4-butyrolactone and butylidenephthalide

4-butyrolactone has been researched along with butylidenephthalide in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's3 (15.79)18.2507
2000's7 (36.84)29.6817
2010's8 (42.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, YZ; Pu, FD1
Kimura, I; Kimura, M; Kobayashi, S; Mimura, Y; Naitoh, T1
Kadota, S; Kohno, S; Matsumoto, K; Ojima, K; Tezuka, Y; Watanabe, H1
Chen, R; Wang, H; Xu, H1
Chen, BM; He, YK; Hu, QN; Li, BY; Liang, YZ; Wang, YL1
He, LC; Liang, MJ; Yang, GD1
Fu, CM; Kan, KK; Lao, SC; Li, P; Li, SP; Wang, YT1
He, LC; Liang, MJ1
Liang, XM; Xiao, YS; Xu, Q; Xue, XY; Yang, F; Zhang, FF1
Shin, S; Sim, Y1
Chen, SN; Jaki, BU; Lankin, DC; Main, M; Pauli, GF; Pro, SM; Schinkovitz, A1
Annie Bligh, SW; Cho, CW; Fan, TP; Fisher, D; Garrard, IJ; Lu, GH; Yeh, JC1
Pan, XB; Sa, RN; Sun, YJ; Wang, YL; Yang, YW; Zhu, SQ1
Huang, Y; Khor, TO; Kong, AN; Saw, CL; Su, ZY; Wang, H; Wu, Q; Xu, X; Yang, Y1
Li, YB; Lou, JS; Su, LN; Wang, YM1
Dind, JX; Gu, ZR; Sun, YJ; Wang, YL1
Chen, Y; Huang, ZF; Liu, YH; Yang, Y; Yi, JH1
Hwang, BY; Kim, GH; Kim, HK; Lee, SJ; Yoon, JU1
Choi, JG; Choi, YJ; Choo, M; Chung, SJ; Jeong, YS; Jin, X; Koo, HR; Lee, BH; Lee, W; Oh, MS; Park, S1

Other Studies

19 other study(ies) available for 4-butyrolactone and butylidenephthalide

ArticleYear
[Studies on the chemical components of the essential oil from the rhizome of Ligusticum sinense Oliv. cv. Chuanxiong hort].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:6

    Topics: 4-Butyrolactone; Bicyclic Monoterpenes; Drugs, Chinese Herbal; Monoterpenes; Oils, Volatile; Phthalic Anhydrides; Terpenes

1988
Chemical structure-activity of cnidium rhizome-derived phthalides for the competence inhibition of proliferation in primary cultures of mouse aorta smooth muscle cells.
    Japanese journal of pharmacology, 1993, Volume: 63, Issue:3

    Topics: 4-Butyrolactone; Analysis of Variance; Animals; Aorta, Thoracic; Benzofurans; Cell Division; Cells, Cultured; Drugs, Chinese Herbal; Male; Mice; Muscle, Smooth, Vascular; Phthalic Anhydrides; Structure-Activity Relationship

1993
Effects of methylenechloride-soluble fraction of Japanese angelica root extract, ligustilide and butylidenephthalide, on pentobarbital sleep in group-housed and socially isolated mice.
    Life sciences, 1998, Volume: 62, Issue:23

    Topics: 4-Butyrolactone; Animals; Brain; Carbolines; Diazepam; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Methoxamine; Methylene Chloride; Mice; Parasympatholytics; Pentobarbital; Phthalic Anhydrides; Plant Extracts; Plant Roots; Plants, Medicinal; Sleep; Social Isolation; Yohimbine

1998
[Chemical constituents of radix Angelicae Sinensis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1998, Volume: 23, Issue:3

    Topics: 4-Butyrolactone; Angelica sinensis; Apiaceae; Drugs, Chinese Herbal; Palmitic Acid; Phthalic Anhydrides; Plants, Medicinal

1998
LC-DAD-APCI-MS-based screening and analysis of the absorption and metabolite components in plasma from a rabbit administered an oral solution of danggui.
    Analytical and bioanalytical chemistry, 2005, Volume: 383, Issue:2

    Topics: 4-Butyrolactone; Absorption; Administration, Oral; Aldehydes; alpha-Linolenic Acid; Angelica sinensis; Animals; Benzofurans; Diynes; Drugs, Chinese Herbal; Fatty Alcohols; Linoleic Acid; Mass Spectrometry; Phthalic Anhydrides; Plant Extracts; Rabbits

2005
Screening, analysis and in vitro vasodilatation of effective components from Ligusticum Chuanxiong.
    Life sciences, 2005, Nov-26, Volume: 78, Issue:2

    Topics: 4-Butyrolactone; Animals; Aorta, Abdominal; Calcium Chloride; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Ligusticum; Muscle, Smooth, Vascular; Norepinephrine; Parasympatholytics; Phthalic Anhydrides; Plant Extracts; Plant Oils; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation

2005
Optimization of pressurized liquid extraction for Z-ligustilide, Z-butylidenephthalide and ferulic acid in Angelica sinensis.
    Journal of pharmaceutical and biomedical analysis, 2006, Mar-18, Volume: 40, Issue:5

    Topics: 4-Butyrolactone; Algorithms; Angelica sinensis; Chromatography, High Pressure Liquid; Coumaric Acids; Particle Size; Phthalic Anhydrides; Pressure; Solvents; Temperature; Ultrasonics

2006
Inhibitory effects of ligustilide and butylidenephthalide on bFGF-stimulated proliferation of rat smooth muscle cells.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:2

    Topics: 4-Butyrolactone; Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Female; Fibroblast Growth Factor 2; Ligusticum; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phthalic Anhydrides; Plants, Medicinal; Rats; Rats, Sprague-Dawley

2006
[High performance liquid chromatography-mass spectrometry analysis of radix Angelica sciensis].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:11

    Topics: 4-Butyrolactone; Angelica sinensis; Benzofurans; Chromatography, High Pressure Liquid; Coumaric Acids; Molecular Structure; Phthalic Anhydrides; Plant Roots; Plants, Medicinal; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2006
Combinatorial anti-Trichophyton effects of Ligusticum chuanxiong essential oil components with antibiotics.
    Archives of pharmacal research, 2008, Volume: 31, Issue:4

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Antifungal Agents; Drug Synergism; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Itraconazole; Ketoconazole; Ligusticum; Microbial Sensitivity Tests; Oils, Volatile; Phthalic Anhydrides; Plant Oils; Plant Roots; Trichophyton

2008
Dynamic nature of the ligustilide complex.
    Journal of natural products, 2008, Volume: 71, Issue:9

    Topics: 4-Butyrolactone; Angelica sinensis; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phthalic Anhydrides; Plant Roots; Plants, Medicinal; Stereoisomerism

2008
Bioactivity-guided fractionation of the volatile oil of Angelica sinensis radix designed to preserve the synergistic effects of the mixture followed by identification of the active principles.
    Journal of chromatography. A, 2012, May-04, Volume: 1236

    Topics: 4-Butyrolactone; Angelica sinensis; Cell Growth Processes; Cell Survival; Countercurrent Distribution; Drug Synergism; Human Umbilical Vein Endothelial Cells; Humans; Oils, Volatile; Phthalic Anhydrides; Plant Extracts; Plant Roots; Robotics

2012
[Study on the dynamic variations of Z-ligustilide and n-butylidenephthalide content in essential oil of radix angelicae sinensis from different growth period].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:11

    Topics: 4-Butyrolactone; Angelica sinensis; Biomass; Gas Chromatography-Mass Spectrometry; Oils, Volatile; Phthalic Anhydrides; Plant Roots; Plants, Medicinal; Seasons

2012
Effects of natural phytochemicals in Angelica sinensis (Danggui) on Nrf2-mediated gene expression of phase II drug metabolizing enzymes and anti-inflammation.
    Biopharmaceutics & drug disposition, 2013, Volume: 34, Issue:6

    Topics: 4-Butyrolactone; Angelica sinensis; Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Gene Expression; Hep G2 Cells; Humans; Interleukin-1beta; Mice; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Nitric Oxide; Phthalic Anhydrides; Phytochemicals; Plant Extracts; RNA, Messenger; Superoxide Dismutase; Superoxide Dismutase-1; Tumor Necrosis Factor-alpha

2013
[Study on the constituents of essential oil of Shunaoxin dropping pills by GC-MS].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2013, Volume: 36, Issue:3

    Topics: 4-Butyrolactone; Angelica; Apiaceae; Benzofurans; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Lactones; Oils, Volatile; Phthalic Anhydrides

2013
[Application of entropy-weight TOPSIS model in synthetical quality evaluation of Angelica sinensis growing in Gansu Province].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:9

    Topics: 4-Butyrolactone; Angelica sinensis; Coumaric Acids; Drugs, Chinese Herbal; Entropy; Medicine, Chinese Traditional; Oils, Volatile; Phthalic Anhydrides

2014
[Comparative Study on Volatile Oil Composition of Chuanxiong Rhizoma, Angelicae Sinensis Radix and Ligustici Rhizoma et Radix].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:6

    Topics: 4-Butyrolactone; Angelica sinensis; Benzofurans; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ligusticum; Oils, Volatile; Phthalic Anhydrides; Plant Oils; Plant Roots; Rhizome

2015
Acaricidal and repellent effects of Cnidium officinale-derived material against Dermanyssus gallinae (Acari: Dermanyssidae).
    Experimental & applied acarology, 2018, Volume: 74, Issue:4

    Topics: 4-Butyrolactone; Acaricides; Animals; Cnidium; Female; Male; Mites; Phthalic Anhydrides; Plant Extracts; Rhizome

2018
Z-ligustilide and n-Butylidenephthalide Isolated from the Aerial Parts of Angelica tenuissima Inhibit Lipid Accumulation In Vitro and In Vivo.
    Planta medica, 2019, Volume: 85, Issue:9-10

    Topics: 4-Butyrolactone; Angelica; Animals; Diet, High-Fat; Drug Evaluation, Preclinical; Gene Expression Regulation; Hep G2 Cells; Humans; Lipid Metabolism; Lipogenesis; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oleic Acid; Phthalic Anhydrides; Plant Components, Aerial; Plant Extracts; Sterol Regulatory Element Binding Protein 1

2019