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4-butyrolactone and benzofurans

4-butyrolactone has been researched along with benzofurans in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (5.77)	18.7374
1990's	3 (5.77)	18.2507
2000's	15 (28.85)	29.6817
2010's	27 (51.92)	24.3611
2020's	4 (7.69)	2.80

Authors

Authors	Studies
Harada, M; Ozaki, Y; Sekita, S	1
Barbier, P; Benezra, C; Ducombs, G; Stampf, JL	1
Némoz, G; Pacheco, H; Picq, M; Prigent, AF	1
Chen, H; Guo, P; Li, ZL; Lin, YK; Zhang, TM	1
Kimura, I; Kimura, M; Kobayashi, S; Mimura, Y; Naitoh, T	1
Chung, GA; Gissurarson, SR; Ingólfsdóttir, K; Skúlason, VG; Vilhelmsdóttir, M	1
Müller, K	1
Liang, H; Lu, XH; Zhao, YY	1
Bucar, F; Ingólfsdóttir, K; Ogmundsdóttir, H; Schneider, I	1
Qin, HL; Su, DM; Yu, SS	1
Chen, BM; He, YK; Hu, QN; Li, BY; Liang, YZ; Wang, YL	1
Cao, J; Ding, M; Kou, H; Wang, Z; Yang, X	1
Li, P; Li, RY; Li, SL; Qi, LW; Sheng, LH; Zhang, LY	1
Karonen, M; Liimatainen, J; Pihlaja, K; Sinkkonen, J	1
Chen, JT; Yang, CR	1
Chan, SS; Cheng, TY; Lin, G	1
Argade, NP; Baag, MM; Puranik, VG	1
Liang, XM; Xiao, YS; Xu, Q; Xue, XY; Yang, F; Zhang, FF	1
Griffin, C; Larichev, V; McNulty, J; Pandey, S; Poloczek, J; Werstiuk, NH	1
Chen, DF; Chen, W; Shen, JG; Wang, CY; Wang, TT; Zeng, HP	1
Chen, C; Du, JR; Tang, J; Wang, CY; Yang, W; Yu, Y	1
Lau, AS; Law, AH; Li, JC; Or, TC; Yang, CL	1
Chen, X; Du, S; Lu, Y; Xu, B; Yao, Z	1
Avila, J; Cerda-García-Rojas, CM; García-Mauriño, S; Gómez-Hurtado, MA; Hernández-Hernández, JD; Joseph-Nathan, P; Manríquez-Torres, JJ; Motilva, V; Román-Marín, LU; Talero, E; Torres-Valencia, JM; Valdez-Calderón, A; Velázquez-Jiménez, R	1
Amicosante, G; Bozzi, A; Brisdelli, F; Celenza, G; Garbarino, JA; Nicoletti, M; Perilli, M; Piovano, M; Sellitri, D	1
Ding, W; Duan, J; Liu, P; Qian, D; Shang, E; Tang, Y; Wu, J	1
Huang, J; Li, GY; Lin, RC; Lu, J; Lu, XQ; Wang, JH; Zhang, C	1
Cheng, MC; Wang, L; Xiao, HB; Zhuo, RJ; Zuo, AH	1
De Petrocellis, L; Di Marzo, V; Morera, E; Nalli, M; Ortar, G; Schiano Moriello, A	1
Li, YB; Lou, JS; Su, LN; Wang, YM	1
Hu, Y; Huang, Y; Jiang, L; Jin, W; Liu, K; Sheikh, MS; Shen, X; Sun, Q	1
Ma, SC; Ren, J; Su, YL; Wang, AG; Wei, Q; Yang, JB	1
Fan, QJ; Kong, FL; Liu, JL; Tan, J; Yang, SM; Yuan, JC; Zheng, SL; Zhou, J	1
El-Naggar, AM; O'Neill, KL; Shrestha, G; St Clair, LL	1
Cheng, X; Su, S; Wink, M	1
Miyanowaki, T; Morinaga, O; Shoyama, Y; Taniyama, R; Tung, NH; Uto, T	1
Cai, H; Pei, K; Qiao, FX; Song, XQ; Tu, PF	1
Bizukojc, M; Boruta, T	1
Chen, Y; Huang, ZF; Liu, YH; Yang, Y; Yi, JH	1
Hu, PY; Liu, D; Tang, Y; Wu, Q; Yang, M; Zheng, Q	1
Guo, Y; Hu, PY; Liu, D; Tang, Y; Yang, M; Yue, P; Zhang, D; Zheng, Q	1
El-Metwally, MM; Frese, M; Hamed, A; Ismail, M; Sewald, N; Shaaban, M; Stammler, HG	1
Chen, K; Chen, L; Chen, Y; Dong, J; Duan, F; Jia, Z; Liu, J; Ma, K; Wang, M; Xiao, H; Xu, W	1
Fukumoto, K; Renzetti, A	1
Bai, G; Deng, YF; Hu, XY; Jiang, M; Lei, W; Ni, JN	1
Hu, N; Jiang, W; Liu, L; Shi, L; Wang, Q; Yan, T; Yang, P; Zhang, S; Zhang, W	1
Bai, DT; Cao, HH; Chen, J; Cheng, M; Gu, LY; Guo, S; Hu, W; Li, L; Lu, TL; Mao, CQ; Yan, WH	1
Banwell, MG; Gardiner, MG; Lan, P; Sheng, B; Sun, P; Vo, Y	1
An, C; Dong, Y; Li, M; Li, X; Wang, X; Xiang, F; Yao, Y	1
Chen, C; Du, JR; Duan, W; Gan, YM; Liu, DL; Yang, YX	1
Chen, J; Jin, L; Shi, T; Xu, X; Zhu, T	1
Hu, YJ; Li, X; Lin, YY; Liu, KL; Shen, XL; Tan, JY; Yang, RY	1

Reviews

2 review(s) available for 4-butyrolactone and benzofurans

Article	Year
Pharmaceutically relevant metabolites from lichens. Applied microbiology and biotechnology, 2001, Volume: 56, Issue:1-2 Topics: 4-Butyrolactone; Anthraquinones; Benzofurans; Depsides; Hydroxybenzoates; Lactones; Lichens; Naphthoquinones	2001
Synthesis of Phthalides and α,β-butenolides by Transition Metal-Catalyzed Activation of C-H Bonds. Molecules (Basel, Switzerland), 2019, Feb-25, Volume: 24, Issue:4 Topics: 4-Butyrolactone; Benzofurans; Catalysis; Coordination Complexes; Cycloaddition Reaction; Molecular Structure; Oxidation-Reduction; Transition Elements	2019

Other Studies

50 other study(ies) available for 4-butyrolactone and benzofurans

Article	Year
[Centrally acting muscle relaxant effect of phthalides (ligustilide, cnidilide and senkyunolide) obtained from Cnidium officinale Makino]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1989, Volume: 109, Issue:6 Topics: 4-Butyrolactone; Animals; Benzofurans; Drugs, Chinese Herbal; Furans; Male; Mephenesin; Muscle Relaxants, Central; Rats; Rats, Inbred Strains	1989
Enantiospecificity in allergic contact dermatitis. A review and new results in Frullania-sensitive patients. Contact dermatitis, 1985, Volume: 13, Issue:2 Topics: 4-Butyrolactone; Animals; Benzofurans; Benzoquinones; Dermatitis, Contact; Guinea Pigs; Humans; Plants; Quinones; Sesquiterpenes; Skin Tests; Stereoisomerism; Structure-Activity Relationship	1985
Selective inhibition of separated forms of cyclic nucleotide phosphodiesterase from rat heart by some cardio- or vaso-active butenolide derivatives. Biochemical pharmacology, 1982, Nov-01, Volume: 31, Issue:21 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 4-Butyrolactone; Animals; Benzofurans; Benzoin; Cytosol; Furans; Isoenzymes; Myocardium; Phosphodiesterase Inhibitors; Purinones; Rats; Vasodilator Agents	1982
[Studies on the chemical components of essential oil from the aerial parts of Ligusticum chuanxiong Hort]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1993, Volume: 18, Issue:9 Topics: 4-Butyrolactone; Benzofurans; Drugs, Chinese Herbal; Oils, Volatile; Sesquiterpenes, Eudesmane; Tetrahydronaphthalenes	1993
Chemical structure-activity of cnidium rhizome-derived phthalides for the competence inhibition of proliferation in primary cultures of mouse aorta smooth muscle cells. Japanese journal of pharmacology, 1993, Volume: 63, Issue:3 Topics: 4-Butyrolactone; Analysis of Variance; Animals; Aorta, Thoracic; Benzofurans; Cell Division; Cells, Cultured; Drugs, Chinese Herbal; Male; Mice; Muscle, Smooth, Vascular; Phthalic Anhydrides; Structure-Activity Relationship	1993
Antimycobacterial activity of lichen metabolites in vitro. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1998, Volume: 6, Issue:2 Topics: 4-Butyrolactone; Anti-Bacterial Agents; Benzofurans; Depsides; Hydroxybenzoates; Lactones; Lichens; Microbial Sensitivity Tests; Mycobacterium; Salicylates	1998
[Isolation and identification of the ligustilide compounds from the root of Angelica sinensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003, Volume: 28, Issue:5 Topics: 4-Butyrolactone; Angelica sinensis; Benzofurans; Molecular Structure; Plant Roots; Plants, Medicinal	2003
Anti-proliferative lichen compounds with inhibitory activity on 12(S)-HETE production in human platelets. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2004, Volume: 11, Issue:7-8 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4-Butyrolactone; Benzoates; Benzofurans; Blood Platelets; Depsides; Emodin; Humans; In Vitro Techniques; Lactones; Lichens; Lipoxygenase; Lipoxygenase Inhibitors; Molecular Structure; Resorcinols; Salicylates	2004
[New dimeric phthalide derivative from Angelica sinensis]. Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:2 Topics: 4-Butyrolactone; Angelica sinensis; Benzofurans; Molecular Conformation; Molecular Structure; Plant Roots; Plants, Medicinal; Stereoisomerism	2005
LC-DAD-APCI-MS-based screening and analysis of the absorption and metabolite components in plasma from a rabbit administered an oral solution of danggui. Analytical and bioanalytical chemistry, 2005, Volume: 383, Issue:2 Topics: 4-Butyrolactone; Absorption; Administration, Oral; Aldehydes; alpha-Linolenic Acid; Angelica sinensis; Animals; Benzofurans; Diynes; Drugs, Chinese Herbal; Fatty Alcohols; Linoleic Acid; Mass Spectrometry; Phthalic Anhydrides; Plant Extracts; Rabbits	2005
[Determination of lactone components in chuanxiong by reversed-phase high performance liquid chromatography]. Se pu = Chinese journal of chromatography, 2005, Volume: 23, Issue:5 Topics: 4-Butyrolactone; Benzofurans; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lactones; Ligusticum; Reproducibility of Results	2005
Live cell extraction and HPLC-MS analysis for predicting bioactive components of traditional Chinese medicines. Journal of pharmaceutical and biomedical analysis, 2006, May-03, Volume: 41, Issue:2 Topics: 4-Butyrolactone; Benzofurans; Cell Extracts; Cells, Cultured; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Endothelial Cells; Humans; Isoflavones; Mass Spectrometry	2006
Lignans from the bark extract of Pinus sylvestris L. Magnetic resonance in chemistry : MRC, 2006, Volume: 44, Issue:6 Topics: 4-Butyrolactone; Acetone; Benzofurans; Guaiacol; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Pinus sylvestris; Plant Extracts; Propylene Glycols; Spectrometry, Mass, Electrospray Ionization; Water	2006
[Studies on chemical constituents from Ligusticum glaucescens Franch]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2006, Volume: 29, Issue:9 Topics: 4-Butyrolactone; Benzofurans; Coumaric Acids; Ligusticum; Methanol; Molecular Structure; Plants, Medicinal; Rhizome	2006
Relaxation effects of ligustilide and senkyunolide A, two main constituents of Ligusticum chuanxiong, in rat isolated aorta. Journal of ethnopharmacology, 2007, May-22, Volume: 111, Issue:3 Topics: 4-Butyrolactone; Animals; Aorta, Thoracic; Benzofurans; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelium, Vascular; Ligusticum; Male; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents	2007
Facile chemo-, regio-, and diastereoselective approach to cis-3,5-disubstituted gamma-butyrolactones and fused gamma-butyrolactones. The Journal of organic chemistry, 2007, Feb-02, Volume: 72, Issue:3 Topics: 4-Butyrolactone; Benzofurans; Cyclohexanones; Esters; Ketones; Lithium Compounds; Molecular Conformation; Stereoisomerism	2007
[High performance liquid chromatography-mass spectrometry analysis of radix Angelica sciensis]. Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:11 Topics: 4-Butyrolactone; Angelica sinensis; Benzofurans; Chromatography, High Pressure Liquid; Coumaric Acids; Molecular Structure; Phthalic Anhydrides; Plant Roots; Plants, Medicinal; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization	2006
Discovery of the apoptosis-inducing activity and high accumulation of the butenolides, menisdaurilide and aquilegiolide in Dicentra spectabilis. Planta medica, 2007, Volume: 73, Issue:15 Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Apoptosis; Benzofurans; Cell Line, Tumor; Fumariaceae; HT29 Cells; Humans; Jurkat Cells; Phytotherapy; Plant Extracts; Plant Leaves; Plant Stems	2007
Characterization of chemical components in extracts from Si-wu decoction with proliferation-promoting effects on rat mesenchymal stem cells. Bioorganic & medicinal chemistry, 2008, May-01, Volume: 16, Issue:9 Topics: 4-Butyrolactone; Animals; Benzofurans; Cell Proliferation; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flow Cytometry; Gas Chromatography-Mass Spectrometry; Mesenchymal Stem Cells; Molecular Structure; Palmitates; Rats; Rats, Sprague-Dawley; Stearates; Structure-Activity Relationship	2008
[Pharmacological activities of Z-ligustilide and metabolites in rats]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2009, Volume: 40, Issue:5 Topics: 4-Butyrolactone; Animals; Benzofurans; Biotransformation; Hydrogen Peroxide; Male; Microsomes, Liver; Oxidative Stress; PC12 Cells; Protective Agents; Rats; Rats, Sprague-Dawley	2009
Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia. Neuropharmacology, 2011, Volume: 60, Issue:6 Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Biological Assay; Cell Line, Tumor; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Humans; Ligusticum; Lipopolysaccharides; Mice; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase Type II; Nitrites; Tumor Necrosis Factor-alpha	2011
[Simultaneous determination of five effective components in Rhizoma Chuanxiong by RP-HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:20 Topics: 4-Butyrolactone; Benzofurans; Calibration; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Pyrazines	2010
Absolute configuration of podophyllotoxin related lignans from Bursera fagaroides using vibrational circular dichroism. Phytochemistry, 2011, Volume: 72, Issue:17 Topics: 4-Butyrolactone; Adenocarcinoma; Antineoplastic Agents, Phytogenic; Benzofurans; Bursera; Cell Line, Tumor; Circular Dichroism; Colonic Neoplasms; Dioxoles; Drugs, Chinese Herbal; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Phytotherapy; Plant Extracts; Plant Exudates; Podophyllotoxin	2011
Cytotoxic activity and antioxidant capacity of purified lichen metabolites: an in vitro study. Phytotherapy research : PTR, 2013, Volume: 27, Issue:3 Topics: 4-Butyrolactone; Anisoles; Antioxidants; Apoptosis; Benzofurans; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Depsides; Free Radical Scavengers; Humans; Hydroxybenzoates; Lactones; Lichens; Oxidative Stress; Reactive Oxygen Species; Salicylates	2013
[Influence of different solutions on extracting of active components in Danggui Chishao drug pair]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:7 Topics: 4-Butyrolactone; Benzoates; Benzofurans; Bridged-Ring Compounds; Chromatography, Liquid; Drugs, Chinese Herbal; Gallic Acid; Glucosides; Hydroxybenzoates; Mass Spectrometry; Monoterpenes; Phthalic Acids; Solvents; Vanillic Acid	2012
Anti-inflammatory ligustilides from Ligusticum chuanxiong Hort. Fitoterapia, 2013, Volume: 91 Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Benzofurans; Drugs, Chinese Herbal; Inflammation; Ligusticum; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; Nitric Oxide; Phytotherapy; Plant Roots	2013
Structure elucidation of degradation products of Z-ligustilide by UPLC-QTOF-MS and NMR spectroscopy. Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:6 Topics: 4-Butyrolactone; Benzofurans; Chromatography, High Pressure Liquid; Hydrolysis; Ligusticum; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Oxidation-Reduction; Plant Roots; Plants, Medicinal; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2013
3-Ylidenephthalides as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators. Bioorganic & medicinal chemistry letters, 2013, Oct-15, Volume: 23, Issue:20 Topics: 4-Butyrolactone; Animals; Benzofurans; HEK293 Cells; Humans; Oxidation-Reduction; Protein Binding; Rats; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels	2013
[Study on the constituents of essential oil of Shunaoxin dropping pills by GC-MS]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2013, Volume: 36, Issue:3 Topics: 4-Butyrolactone; Angelica; Apiaceae; Benzofurans; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Lactones; Oils, Volatile; Phthalic Anhydrides	2013
Lappaol F, a novel anticancer agent isolated from plant arctium Lappa L. Molecular cancer therapeutics, 2014, Volume: 13, Issue:1 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Apoptosis; Arctium; Benzofurans; Cell Cycle Checkpoints; Cell Line, Tumor; Humans; Mice; Neoplasms; Plant Extracts; Xenograft Model Antitumor Assays	2014
New dimeric phthalides from Ligusticum sinense Oliv cv. Chaxiong. Journal of Asian natural products research, 2014, Volume: 16, Issue:7 Topics: 4-Butyrolactone; Benzofurans; Crystallography, X-Ray; Drugs, Chinese Herbal; Ligusticum; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Rhizome	2014
[Quantitative determination of 5 active ingredients in different harvest periods of Ligusticum chuanxiong by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:9 Topics: 4-Butyrolactone; Acetic Acid; Acetonitriles; Benzofurans; Chromatography, High Pressure Liquid; Coumaric Acids; Ligusticum; Methanol; Solvents; Time Factors	2014
Anticancer activities of selected species of North American lichen extracts. Phytotherapy research : PTR, 2015, Volume: 29, Issue:1 Topics: 4-Butyrolactone; Antineoplastic Agents; Apoptosis; Benzofurans; Cell Line, Tumor; Cell Survival; Humans; Inhibitory Concentration 50; Lactones; Lichens; Lymphocytes; Molecular Structure; Salicylates; Thymidine Kinase; Tumor Suppressor Protein p53; United States	2015
Natural lignans from Arctium lappa modulate P-glycoprotein efflux function in multidrug resistant cancer cells. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, Feb-15, Volume: 22, Issue:2 Topics: 4-Butyrolactone; Antineoplastic Agents; Arctium; ATP Binding Cassette Transporter, Subfamily B; Benzofurans; Caco-2 Cells; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Furans; Glucosides; Humans; Lignans; Molecular Structure; Rhodamine 123; Seeds	2015
Anti-inflammatory Activity of Constituents Isolated from Aerial Part of Angelica acutiloba Kitagawa. Phytotherapy research : PTR, 2015, Volume: 29, Issue:12 Topics: 4-Butyrolactone; Angelica; Animals; Anti-Inflammatory Agents; Benzofurans; Dinoprostone; Diynes; Fatty Alcohols; Furocoumarins; Heme Oxygenase-1; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; Nitric Oxide; Phytochemicals; Plant Components, Aerial; Plant Extracts; Plant Roots; Plants, Medicinal; RAW 264.7 Cells; Tumor Necrosis Factor-alpha	2015
[Establishment and application of HPLC-QAMS for quality evaluation of Chuanxiong Rhizoma]. Yao xue xue bao = Acta pharmaceutica Sinica, 2015, Volume: 50, Issue:6 Topics: 4-Butyrolactone; Acetonitriles; Benzofurans; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Hydroxybenzoates; Quality Control; Rhizome	2015
Induction of secondary metabolism of Aspergillus terreus ATCC 20542 in the batch bioreactor cultures. Applied microbiology and biotechnology, 2016, Volume: 100, Issue:7 Topics: 4-Butyrolactone; Anthraquinones; Aspergillus; Batch Cell Culture Techniques; Benzofurans; Biomass; Bioreactors; Chromatography, High Pressure Liquid; Cyclopentanes; Fatty Acids, Monounsaturated; Fermentation; Inulin; Lovastatin; Phenyl Ethers; Pyridones; Rapeseed Oil; Secondary Metabolism	2016
[Comparative Study on Volatile Oil Composition of Chuanxiong Rhizoma, Angelicae Sinensis Radix and Ligustici Rhizoma et Radix]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:6 Topics: 4-Butyrolactone; Angelica sinensis; Benzofurans; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ligusticum; Oils, Volatile; Phthalic Anhydrides; Plant Oils; Plant Roots; Rhizome	2015
Elucidation of Transport Mechanism of Paeoniflorin and the Influence of Ligustilide, Senkyunolide I and Senkyunolide A on Paeoniflorin Transport through Mdck-Mdr1 Cells as Blood-Brain Barrier in Vitro Model. Molecules (Basel, Switzerland), 2016, Mar-02, Volume: 21, Issue:3 Topics: 4-Butyrolactone; Animals; ATP Binding Cassette Transporter, Subfamily B; Benzofurans; Biological Transport; Blood-Brain Barrier; Dogs; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucosides; Humans; In Vitro Techniques; Madin Darby Canine Kidney Cells; Molecular Structure; Monoterpenes	2016
The influence and mechanism of ligustilide, senkyunolide I, and senkyunolide A on echinacoside transport through MDCK-MDR1 cells as blood-brain barrier in vitro model. Phytotherapy research : PTR, 2018, Volume: 32, Issue:3 Topics: 4-Butyrolactone; Animals; Benzofurans; Biological Transport; Blood-Brain Barrier; Dogs; Drugs, Chinese Herbal; Glycosides; Humans; Madin Darby Canine Kidney Cells	2018
X-ray, structural assignment and molecular docking study of dihydrogeodin from Aspergillus Terreus TM8. Natural product research, 2019, Volume: 33, Issue:1 Topics: 4-Butyrolactone; Antiviral Agents; Aspergillus; Benzofurans; Benzophenones; Crystallography, X-Ray; Cyclophilin A; Immunosuppressive Agents; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure	2019
Preparing the key metabolite of Z-ligustilide in vivo by a specific electrochemical reaction. Journal of separation science, 2018, Volume: 41, Issue:13 Topics: 4-Butyrolactone; Animals; Benzofurans; Drugs, Chinese Herbal; Electrochemistry; Leuconostoc mesenteroides; Mass Spectrometry; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Sprague-Dawley	2018
Phthalides, senkyunolide A and ligustilide, show immunomodulatory effect in improving atherosclerosis, through inhibiting AP-1 and NF-κB expression. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 117 Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Apolipoproteins E; Atherosclerosis; Benzofurans; HEK293 Cells; Humans; Immunologic Factors; Inflammation Mediators; Lipids; Male; Mice, Inbred C57BL; NF-kappa B; Proto-Oncogene Proteins c-akt; Transcription Factor AP-1; Tumor Necrosis Factor Receptor Superfamily, Member 9	2019
Simultaneous quantification of ligustilide, dl-3-n-butylphthalide and senkyunolide A in rat plasma by GC-MS and its application to comparative pharmacokinetic studies of Rhizoma Chuanxiong extract alone and Baizhi Chuanxiong Decoction. Biomedical chromatography : BMC, 2019, Volume: 33, Issue:10 Topics: 4-Butyrolactone; Administration, Oral; Animals; Benzofurans; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Limit of Detection; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results	2019
[UPLC fingerprint and multi-components content determination of different processed products of Angelica sinensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2019, Volume: 44, Issue:12 Topics: 4-Butyrolactone; Angelica sinensis; Benzofurans; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Hydroxybenzoates; Medicine, Chinese Traditional; Principal Component Analysis	2019
Direct and Metal-Catalyzed Photochemical Dimerization of the Phthalide ( Organic letters, 2019, 08-16, Volume: 21, Issue:16 Topics: 4-Butyrolactone; Benzofurans; Catalysis; Crystallography, X-Ray; Cycloaddition Reaction; Dimerization; Metals; Molecular Structure; Photochemistry	2019
Simultaneous determination of 20 bioactive components in Chuanxiong Rhizoma from different production origins in Sichuan province by ultra-high-performance liquid chromatography coupled with triple quadrupole mass spectrometry combined with multivariate s Electrophoresis, 2020, Volume: 41, Issue:18-19 Topics: 4-Butyrolactone; Benzofurans; China; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Geography; Limit of Detection; Linear Models; Multivariate Analysis; Reproducibility of Results; Tandem Mass Spectrometry	2020
Phthalide derivative CD21 alleviates cerebral ischemia-induced neuroinflammation: Involvement of microglial M2 polarization via AMPK activation. European journal of pharmacology, 2020, Nov-05, Volume: 886 Topics: 4-Butyrolactone; AMP-Activated Protein Kinases; Animals; Behavior, Animal; Benzofurans; Brain Ischemia; Cell Line; Cell Polarity; Cytokines; Dose-Response Relationship, Drug; Encephalitis; Enzyme Activation; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Phenotype; Psychomotor Performance	2020
Quality suitability regionalization analysis of Angelica sinensis in Gansu, China. PloS one, 2020, Volume: 15, Issue:12 Topics: 4-Butyrolactone; Angelica sinensis; Benzofurans; China; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Plant Extracts	2020
Lappaol F, an anticancer agent, inhibits YAP via transcriptional and post-translational regulation. Pharmaceutical biology, 2021, Volume: 59, Issue:1 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Benzofurans; Cell Cycle Proteins; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Protein Processing, Post-Translational; Transcription Factors; Transcription, Genetic; Xenograft Model Antitumor Assays	2021