4-butyrolactone has been researched along with baclofen in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (38.46) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Demarest, KT; Moore, KE | 1 |
| Costentin, J; Marcais, H; Protais, P | 1 |
| Gianutsos, G; Moore, KE | 1 |
| Fang, VS; Meltzer, HY | 1 |
| Gudelsky, GA; Moore, KE | 1 |
| Agnati, L; Fuxe, K; Hökfelt, T; Johansson, O; Ljungdahl, A; Perez de la Mora, M | 1 |
| Agnati, L; Everitt, BJ; Fuxe, K; Hökfelt, T; Ljungdahl, A; Perez de la Mora, M | 1 |
| Bernasconi, R; Bittiger, H; Lauber, J; Leonhardt, T; Marescaux, C; Martin, P; Reymann, N; Rubio, V; Vergnes, M | 1 |
| Baba, M; Iishi, H; Nakaizumi, A; Taniguchi, H; Tatsuta, M; Uehara, H | 1 |
| Waldmeier, PC | 1 |
| Chmielewska, B; Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, WA | 1 |
| Argiolas, A; Fadda, F; Gessa, GL; Marcou, M; Melis, MR; Porceddu, ML | 1 |
| Broxterman, HJ; Noach, EL; van Valkenburg, CF; Wijling, A | 1 |
| Aizawa, M; Fukuda, H; Ito, Y | 1 |
| Jeong, MJ; Keum, S; Kim, D; Kim, SS; Lee, T; McEnery, MW; Shin, HS; Song, I | 1 |
| Bettler, B; Bräuner-Osborne, H; Cryan, JF; Froestl, W; Kaupmann, K; Klebs, K; Mombereau, C; Mosbacher, J; Sansig, G; Schmutz, M; van der Putten, H; Waldmeier, P; Wellendorph, P | 1 |
| Carter, LP; Chen, W; Coop, A; France, CP; Koek, W; Lamb, RJ; Wu, H | 1 |
| Carter, LP; Coop, A; France, CP; Koek, W; Wu, H | 1 |
| Carter, LP; France, CP; Koek, W | 1 |
| Coop, A; Koek, W; Mercer, SL | 1 |
| Baker, LE; Poling, A; Pynnonen, DM; Searcy, GD | 1 |
| Crowe, SF; Hale, MW; Hazi, A; Milsome, SL; Sherry, JM | 1 |
| Aleem, IS; Ashraf, A; Cortez, MA; Kanawaty, A; Liu, CC; Sadeghnia, HR; Shen, L; Snead, OC; Stewart, L; Trepanier, CH; Wu, Y | 1 |
| Coop, A; France, CP; Koek, W; Mercer, SL | 1 |
| Bell, J; Collins, R | 1 |
| Brett, J; Ezard, N; Freeman, G; Lindsey, R; Roberts, DM; Rodgers, C; Siefried, KJ | 1 |
26 other study(ies) available for 4-butyrolactone and baclofen
| Article | Year |
|---|---|
Comparison of dopamine synthesis regulation in the terminals of nigrostriatal, mesolimbic, tuberoinfundibular and tuberohypophyseal neurons.
Topics: 4-Butyrolactone; Animals; Apomorphine; Baclofen; Benzyl Alcohols; Dihydroxyphenylalanine; Dopamine; Hydrazines; Hypothalamo-Hypophyseal System; Male; Median Eminence; Nialamide; Olfactory Bulb; Piribedil; Pituitary Gland, Posterior; Rats; Reserpine | 1979 |
Hypersensitivity of the climbing behaviour response to apomorphine induced by a short depression of dopaminergic neurone activity.
Topics: 4-Butyrolactone; Animals; Apomorphine; Baclofen; Cycloheximide; Dopamine; Hydroxybutyrates; Male; Mice; Motor Activity; Neurons; Sodium Oxybate | 1979 |
Tolerance to the effects of baclofen and gamma-butyrolactone on locomotor activity and dopaminergic neurons in the mouse.
Topics: 4-Butyrolactone; Aminobutyrates; Animals; Baclofen; Brain; Dopamine; Drug Tolerance; Furans; Male; Mice; Mice, Inbred ICR; Motor Activity; Neurons | 1978 |
Effect of gamma-butyrolactone and baclofen on plasma prolactin in male rats.
Topics: 4-Butyrolactone; Aminobutyrates; Animals; Baclofen; Dose-Response Relationship, Drug; Furans; Male; Methyltyrosines; Prolactin; Rats; Trifluoperazine | 1977 |
Drug actions on dopamine turnover in the median eminence.
Topics: 4-Butyrolactone; Animals; Baclofen; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Interactions; Female; Haloperidol; Hypothalamo-Hypophyseal System; Kinetics; Male; Median Eminence; Methyltyrosines; Prolactin; Rats | 1977 |
Regulation of the mesocortical dopamine neurons.
Topics: 4-Butyrolactone; Acetylcholine; Aminooxyacetic Acid; Baclofen; Cerebral Cortex; Dopamine; gamma-Aminobutyric Acid; Isoxazoles; Neurons; Pimozide; Pyrrolidinones; Sulpiride | 1977 |
Action of beta(4-chlorphenyl)GABA, gamma-hydroxybutyrolactone, and apomorphine on central dopamine neurons.
Topics: 4-Butyrolactone; Aminobutyrates; Animals; Apomorphine; Baclofen; Brain; Castration; Dopamine; Estrogens; Female; Furans; Neurons; Piribedil; Rats; Receptors, Dopamine; Sexual Behavior, Animal; Time Factors | 1977 |
Experimental absence seizures: potential role of gamma-hydroxybutyric acid and GABAB receptors.
Topics: 4-Butyrolactone; Animals; Baclofen; Brain; Cyclic GMP; Disease Models, Animal; Epilepsy, Absence; GABA-A Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values; Reproducibility of Results; Sodium Oxybate; Valproic Acid | 1992 |
Effect of gamma-butyrolactone on baclofen inhibition of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Topics: 4-Butyrolactone; Animals; Baclofen; DNA; Gastric Juice; Gastrins; Hydrogen-Ion Concentration; Male; Methylnitronitrosoguanidine; Rats; Rats, Inbred Strains; Secretory Rate; Stomach Neoplasms | 1992 |
The GABAB antagonist, CGP 35348, antagonizes the effects of baclofen, gamma-butyrolactone and HA 966 on rat striatal dopamine synthesis.
Topics: 4-Butyrolactone; Animals; Baclofen; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; GABA-A Receptor Antagonists; Haloperidol; Organophosphorus Compounds; Pyrrolidinones; Rats; Tetrabenazine | 1991 |
Modification of the anticonvulsant activity of 2-amino-5-phosphonovalerate by agents affecting different neurotransmitter systems.
Topics: 2-Amino-5-phosphonovalerate; 4-Butyrolactone; Animals; Anticonvulsants; Atropine; Baclofen; Brain; Drug Interactions; Male; Mice; Muscimol; Neurotransmitter Agents; Sodium Oxybate; Synaptic Transmission; Valine | 1985 |
Delayed inhibition of dopamine synthesis by gamma-butyrolactone and baclofen: dopamine autoreceptor supersensitivity?
Topics: 4-Butyrolactone; Animals; Apomorphine; Baclofen; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Furans; Haloperidol; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Time Factors | 1982 |
Cross-tolerance of dopamine metabolism to baclofen, gamma-butyrolactone and HA-966 in the striatum and olfactory tubercle of the rat.
Topics: 4-Butyrolactone; Animals; Apomorphine; Baclofen; Central Nervous System Depressants; Corpus Striatum; Dopamine; Drug Tolerance; Male; Olfactory Bulb; Pyrrolidinones; Rats | 1981 |
Roles of gamma-aminobutyric acidB (GABA B) and gamma-hydroxybutyric acid receptors in hippocampal long-term potentiation and pathogenesis of absence seizures.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Baclofen; Benzocycloheptenes; Electroencephalography; Epilepsy, Absence; Female; GABA Agonists; GABA Modulators; Hippocampus; Long-Term Potentiation; Male; Mice; Receptors, Cell Surface; Receptors, GABA-B | 1997 |
Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G) T-type Ca(2+) channels.
Topics: 4-Butyrolactone; Animals; Baclofen; Calcium Channels, T-Type; Cerebral Cortex; Electroencephalography; Epilepsy, Absence; Immunity, Innate; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Protein Subunits; Receptors, GABA-B; Seizures; Thalamic Nuclei; Thalamus | 2001 |
Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.
Topics: 4-Butyrolactone; Adjuvants, Anesthesia; Animals; Anticonvulsants; Autoradiography; Baclofen; Behavior, Animal; Benzocycloheptenes; Binding, Competitive; Body Weight; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Electroencephalography; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Organophosphorus Compounds; Phenols; Radioligand Assay; Receptors, GABA-B; Sodium Oxybate; Time Factors | 2003 |
Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) in rats discriminating GHB from baclofen and diazepam.
Topics: 4-Butyrolactone; Anesthetics, Intravenous; Animals; Baclofen; Benzocycloheptenes; Benzylamines; Butylene Glycols; Diazepam; Discrimination, Psychological; Dithiothreitol; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Organophosphorus Compounds; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Sodium Oxybate | 2005 |
Discriminative stimulus effects of flumazenil: perceptual masking by baclofen, and lack of substitution with gamma-hydroxybutyrate and its precursors 1,4-butanediol and gamma-butyrolactone.
Topics: 4-Butyrolactone; Animals; Baclofen; Benzocycloheptenes; Butylene Glycols; Columbidae; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Organophosphorus Compounds; Sodium Oxybate | 2006 |
Lack of effects of GHB precursors GBL and 1,4-BD following i.c.v. administration in rats.
Topics: 4-Butyrolactone; Anesthetics, Intravenous; Animals; Baclofen; Behavior, Animal; Blood-Brain Barrier; Brain; Butylene Glycols; GABA Agonists; Injections, Intraperitoneal; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Sodium Oxybate | 2006 |
Cataleptic effects of gamma-hydroxybutyrate (GHB), its precursor gamma-butyrolactone (GBL), and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348.
Topics: 4-Butyrolactone; Animals; Baclofen; Catalepsy; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; Male; Mice; Mice, Inbred C57BL; Narcolepsy; Organophosphorus Compounds; Receptors, GABA-B; Sodium Oxybate; Substance-Related Disorders | 2007 |
Differentiating the discriminative stimulus effects of gamma-hydroxybutyrate and ethanol in a three-choice drug discrimination procedure in rats.
Topics: 4-Butyrolactone; Animals; Baclofen; Benzocycloheptenes; Butylene Glycols; Discrimination, Psychological; Ethanol; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Ketamine; Male; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Sodium Oxybate | 2008 |
Gamma-butyrolactone (GBL) disruption of passive avoidance learning in the day-old chick appears to be due to its effect on GABAB not gamma-hydroxybutyric [corrected] acid (GHB) receptors.
Topics: 4-Butyrolactone; Animals; Avoidance Learning; Baclofen; Chickens; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; Injections, Subcutaneous; Male; Memory; Microinjections; Receptors, Cell Surface; Solvents; Time Factors | 2009 |
Infantile spasms and Down syndrome: a new animal model.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Baclofen; Brain; Disease Models, Animal; Down Syndrome; Electroencephalography; Ethosuximide; GABA Agonists; Genotype; Humans; Infant; Mice; Mice, Mutant Strains; Organophosphorus Compounds; Phenotype; Receptors, GABA-A; Receptors, GABA-B; Spasms, Infantile; Time Factors; Valproic Acid; Vigabatrin | 2009 |
Behavioral effects of gamma-hydroxybutyrate, its precursor gamma-butyrolactone, and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl(diethoxymethyl)phosphinic acid (CGP35348).
Topics: 4-Butyrolactone; Anesthetics, Intravenous; Animals; Baclofen; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Injections, Intramuscular; Kinetics; Organophosphorus Compounds; Sodium Oxybate | 2009 |
Gamma-butyrolactone (GBL) dependence and withdrawal.
Topics: 4-Butyrolactone; Adult; Ambulatory Care; Baclofen; Delirium; Diazepam; Dose-Response Relationship, Drug; Female; Hospitalization; Humans; Male; Muscle Relaxants, Central; Outpatient Clinics, Hospital; Recurrence; Solvents; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome; Young Adult | 2011 |
Inpatient GHB withdrawal management in an inner-city hospital in Sydney, Australia: a retrospective medical record review.
Topics: 4-Butyrolactone; Baclofen; Delirium; Diazepam; Female; Hospitals, Urban; Humans; Inpatients; Male; Medical Records; Prospective Studies; Retrospective Studies; Sodium Oxybate; Substance Withdrawal Syndrome | 2023 |