Page last updated: 2024-08-18

4-butyrolactone and 3-benzyl-5-((2-nitrophenoxy)methyl)dihydrofuran-2(3h)-one

4-butyrolactone has been researched along with 3-benzyl-5-((2-nitrophenoxy)methyl)dihydrofuran-2(3h)-one in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's8 (72.73)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Huang, B; Meng, N; Miao, J; Zhang, S; Zhang, Y; Zhao, B; Zhao, J1
Bi, J; Miao, J; Peng, N; Wang, P; Wang, S; Wei, L; Xie, Z; Yang, H; Yang, S; Zhao, B; Zhao, C1
Meng, N; Miao, J; Su, L; Zhang, S; Zhang, Y; Zhao, B; Zhao, J1
Bi, J; Miao, J; Wang, P; Wei, L; Xie, Z; Xu, S; Yang, H; Yang, S; Zhao, B; Zhao, C1
Ge, D; Han, L; Huang, S; Jiang, Z; Kung, H; Miao, J; Peng, N; Su, L; Wang, P; Zhang, S; Zhang, Y; Zhao, B; Zhao, J1
Meng, N; Miao, J; Peng, N; Su, L; Wang, S; Zhang, S; Zhang, Y; Zhao, B; Zhao, F; Zhao, J1
Huang, S; Meng, N; Miao, J; Peng, N; Su, L; Wang, SQ; Zhang, S; Zhang, Y; Zhao, B; Zhao, J1
Han, L; Lu, W; Miao, J; Su, L; Zhang, S; Zhang, Y; Zhao, B; Zhao, J1
Dai, J; Huang, J; Jiang, R; Tang, L; Tian, R; Yang, Y; Zhang, L1
Kim, YH; Lee, S; Park, S; Rakhmanova, V; Shin, J1
Chen, H; Chen, S; Guo, M; Huang, Y; Jia, D; Lao, J; Li, Q; Liang, J; Tong, J1

Other Studies

11 other study(ies) available for 4-butyrolactone and 3-benzyl-5-((2-nitrophenoxy)methyl)dihydrofuran-2(3h)-one

ArticleYear
Protective effects of a synthesized butyrolactone derivative against chloroquine-induced autophagic vesicle accumulation and the disturbance of mitochondrial membrane potential and Na+,K+-ATPase activity in vascular endothelial cells.
    Chemical research in toxicology, 2009, Mar-16, Volume: 22, Issue:3

    Topics: 4-Butyrolactone; Autophagy; Cells, Cultured; Chloroquine; Cytoplasmic Vesicles; Endothelial Cells; Humans; Membrane Potential, Mitochondrial; Sodium-Potassium-Exchanging ATPase

2009
Butyrolactone derivative 3-benzyl-5-((2-nitrophenoxy) methyl)-dihydrofuran-2(3H)-one protects against amyloid-β peptides-induced cytotoxicity in PC12 cells.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 28, Issue:2

    Topics: 4-Butyrolactone; Amyloid beta-Peptides; Animals; Autophagy; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Membrane Potential, Mitochondrial; Microtubule-Associated Proteins; PC12 Cells; Peptide Fragments; Rats; Reactive Oxygen Species; Sirolimus; Sodium-Potassium-Exchanging ATPase; Time Factors

2012
A butyrolactone derivative suppressed lipopolysaccharide-induced autophagic injury through inhibiting the autoregulatory loop of p8 and p53 in vascular endothelial cells.
    The international journal of biochemistry & cell biology, 2012, Volume: 44, Issue:2

    Topics: 4-Butyrolactone; Acetylcysteine; Apoptosis; Autophagy; Basic Helix-Loop-Helix Transcription Factors; Endothelial Cells; Endothelium, Vascular; Homeostasis; Humans; Lipopolysaccharides; Membrane Potential, Mitochondrial; Reactive Oxygen Species; Tumor Suppressor Protein p53

2012
A butyrolactone derivative 3BDO alleviates memory deficits and reduces amyloid-β deposition in an AβPP/PS1 transgenic mouse model.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 30, Issue:3

    Topics: 4-Butyrolactone; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autophagy; Brain; Disease Models, Animal; Insulysin; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Neprilysin; Presenilin-1; Signal Transduction

2012
Identification of a novel MTOR activator and discovery of a competing endogenous RNA regulating autophagy in vascular endothelial cells.
    Autophagy, 2014, Volume: 10, Issue:6

    Topics: 3' Untranslated Regions; 4-Butyrolactone; Adaptor Proteins, Signal Transducing; Autophagy; Autophagy-Related Proteins; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; MicroRNAs; Models, Molecular; Phosphorylation; Poly(A)-Binding Proteins; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Long Noncoding; Signal Transduction; Sirolimus; T-Cell Intracellular Antigen-1; Tacrolimus Binding Proteins; TOR Serine-Threonine Kinases; Transforming Growth Factor beta2

2014
An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E⁻/⁻ mice.
    Scientific reports, 2014, Jul-01, Volume: 4

    Topics: 4-Butyrolactone; Animals; Apolipoproteins E; Atherosclerosis; Autophagy; Dose-Response Relationship, Drug; Endothelial Cells; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; TOR Serine-Threonine Kinases; Treatment Outcome

2014
Heterogeneous nuclear ribonucleoprotein E1 regulates protein disulphide isomerase translation in oxidized low-density lipoprotein-activated endothelial cells.
    Acta physiologica (Oxford, England), 2015, Volume: 213, Issue:3

    Topics: 4-Butyrolactone; 5' Untranslated Regions; Animals; Apolipoproteins E; Atherosclerosis; Binding Sites; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; Heterogeneous-Nuclear Ribonucleoproteins; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, LDL; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phosphorylation; Protein Disulfide-Isomerases; Proteomics; Proto-Oncogene Proteins c-akt; RNA-Binding Proteins; Transfection

2015
A 3'UTR-associated RNA, FLJ11812 maintains stemness of human embryonic stem cells by targeting miR-4459.
    Stem cells and development, 2015, May-01, Volume: 24, Issue:9

    Topics: 3' Untranslated Regions; 4-Butyrolactone; Adaptor Proteins, Signal Transducing; Autophagy-Related Proteins; Cdc20 Proteins; Cell Differentiation; Embryonic Stem Cells; HEK293 Cells; Humans; MicroRNAs; RNA, Long Noncoding

2015
The SIRT1 inhibitor EX-527 suppresses mTOR activation and alleviates acute lung injury in mice with endotoxiemia.
    Innate immunity, 2017, Volume: 23, Issue:8

    Topics: 4-Butyrolactone; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Animals; Carbazoles; Carrier Proteins; Cell Cycle Proteins; Endotoxemia; Eukaryotic Initiation Factors; Interleukin-6; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Phosphoproteins; Phosphorylation; Plasminogen Activator Inhibitor 1; Sirtuin 1; Thromboplastin; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha

2017
3-Benzyl-5-((2-nitrophenoxy) methyl)-dihydrofuran-2(3H)-one suppresses FcεRI-mediated mast cell degranulation via the inhibition of mTORC2-Akt signaling.
    Biochemical and biophysical research communications, 2020, 01-01, Volume: 521, Issue:1

    Topics: 4-Butyrolactone; Animals; Cell Degranulation; Mast Cells; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt; Receptors, IgE; Signal Transduction

2020
3BDO Alleviates Seizures and Improves Cognitive Function by Regulating Autophagy in Pentylenetetrazol (PTZ)-Kindled Epileptic Mice Model.
    Neurochemical research, 2022, Volume: 47, Issue:12

    Topics: 4-Butyrolactone; Animals; Autophagy; Cognition; Disease Models, Animal; Epilepsy; Hippocampus; Kindling, Neurologic; Mice; Pentylenetetrazole; Ribosomal Protein S6 Kinases, 70-kDa; Seizures; TOR Serine-Threonine Kinases

2022