4-bromomethyl-7-methoxycoumarin has been researched along with trimetrexate in 1 studies
| Studies (4-bromomethyl-7-methoxycoumarin) | Trials (4-bromomethyl-7-methoxycoumarin) | Recent Studies (post-2010) (4-bromomethyl-7-methoxycoumarin) | Studies (trimetrexate) | Trials (trimetrexate) | Recent Studies (post-2010) (trimetrexate) |
|---|---|---|---|---|---|
| 27 | 0 | 0 | 422 | 50 | 21 |
| Protein | Taxonomy | 4-bromomethyl-7-methoxycoumarin (IC50) | trimetrexate (IC50) |
|---|---|---|---|
| Dihydrofolate reductase | Mycobacterium avium | 0.3012 | |
| Dihydrofolate reductase | Homo sapiens (human) | 0.0207 | |
| Dihydrofolate reductase | Lacticaseibacillus casei | 0.1435 | |
| Dihydrofolate reductase | Saccharomyces cerevisiae S288C | 0.042 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 0.1798 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.026 | |
| Dihydrofolate reductase | Pneumocystis carinii | 0.0378 | |
| Dihydrofolate reductase | Candida albicans | 0.04 | |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | 0.01 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.008 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 0.5788 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Trypanosoma cruzi | 0.0202 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 0.0794 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Griffin, RJ; Lambert, PA; Robson, C; Twentyman, PR; Wright, KA | 1 |
1 other study(ies) available for 4-bromomethyl-7-methoxycoumarin and trimetrexate
| Article | Year |
|---|---|
Chemical synthesis and biological properties of novel fluorescent antifolates in Pgp- and MRP-overexpressing tumour cell lines.
Topics: 4-Chloro-7-nitrobenzofurazan; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Dansyl Compounds; Drug Screening Assays, Antitumor; Fluorescent Dyes; Folic Acid Antagonists; Growth Inhibitors; Humans; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Pyrimidines; Tetrahydrofolate Dehydrogenase; Trimetrexate; Tumor Cells, Cultured; Umbelliferones | 1998 |