Compounds > 4-boronophenylalanine
Page last updated: 2024-08-23

4-boronophenylalanine and boron

4-boronophenylalanine has been researched along with boron in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.85)18.7374
1990's20 (37.04)18.2507
2000's22 (40.74)29.6817
2010's8 (14.81)24.3611
2020's3 (5.56)2.80

Authors

AuthorsStudies
Hori, Y; Ichihashi, M; Komura, A; Mishima, Y; Shiono, M; Yamamura, K; Yoshino, K1
Mishima, Y1
Coderre, J; Fairchild, R; Hansrote, J; Packer, S; Perry, H; Saraf, S1
Hatta, S; Honda, C; Ichihashi, M; Mishima, Y1
Coderre, JA; Glass, JD; Greenberg, D; Micca, P; Packer, S1
Barth, RF; Fairchild, RG; Soloway, AH1
Ichihashi, M; Mishima, Y; Tsuji, M1
Bywaters, A; Coderre, JA; Hopewell, JW; Liu, HB; Micca, PL; Morris, GM; Nawrocky, MM1
Allen, BJ; Halliday, GM; Harding, AJ; Moore, DE; Setiawan, Y1
Honda, C; Ichihashi, M; Mishima, Y; Wadabayashi, N1
Bennett, BD; Coderre, JA; Morrison, GH; Mumford-Zisk, J1
Coderre, JA; Hopewell, JW; Micca, PL; Morris, GM; Rezvani, M1
Feinendegen, LE; Müller-Gärtner, HW; Papaspyrou, M1
Allen, BJ; Jones, R; Mallesch, JL; McCarthy, WH; Moore, DE; Stening, WA1
Bailey, MQ; Barth, RF; Coderre, JA; Matalka, KZ; Moeschberger, ML; Rofstad, EK; Soloway, AH; Staubus, AE1
Capala, J; Coderre, JA; Makar, MS1
Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Gebbers, JO; Joel, DD; Micca, PL; Nawrocky, MM; Peress, NS; Shady, M; Slatkin, DN1
Akaboshi, M; Kinashi, Y; Kobayashi, T; Masunaga, S; Ono, K; Sakurai, Y; Suzuki, M; Takagaki, M1
Capala, J; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Iwai, J; Joel, DD; Liu, HB; Wielopolski, L1
Fujii, R; Ido, T; Imahori, Y; Kobayashi, T; Kusuki, T; Ohmori, Y; Ono, K; Sakae, K; Takagaki, M; Ueda, S2
Hiratsuka, J; Imajo, Y; Kondoh, H; Mishima, Y; Yoshino, K1
Coderre, JA; Hoch, DA; Kalef-Ezra, JA; Lombardo, DT; Ma, R; Micca, PL; Miura, M; Morris, GM; Slatkin, DN; Youngs, KM1
Busse, PM; Kiger, WS; Palmer, MR; Riley, KJ; Zamenhof, RG1
Cassapo, R; Castro, M; Chaveca, T; Fernandes, AP; Gonçalves, IC; Oliveira, NG; Rodrigues, AS; Rueff, J; Toscano-Rico, JM1
Barth, RF; Chandra, S; Coderre, JA; Joel, DD; Smith, DR; Yang, W1
Batistoni, D; Dagrosa, A; Farías, S; Garavaglia, R; Itoiz, ME; Kreimann, EL; Schwint, AE1
Ehara, K; Hiratsuka, J; Iwakura, M; Kondoh, H; Mishima, Y; Tamaki, N1
Agote, M; Cabrini, RL; Dadino, JL; Dagrosa, MA; Farías, S; Garavaglia, R; Juvenal, GJ; Kreimann, E; Pisarev, MA; Viaggi, M1
Chandra, S; Coderre, JA; Kabalka, GW; Lorey, DR; Smith, DR1
Braun, I; Braun, K; Corban-Wilhelm, H; Debus, J; Ehemann, V; Eisenmenger, A; Heckl, S; Jenne, J; Pipkorn, R; Rastert, R; Waldeck, W; Wolber, G1
Kato, I; Masunaga, S; Nagata, K; Obayashi, S; Ono, K; Sakurai, Y; Suzuki, M; Yura, Y1
Filippov, VI; Komissarova, LKh; Kuznetsov, AA; Kuznetsov, OA; Podoynitsyn, SN1
Basilico, F; Mauri, PL; Moss, R; Pozzi, F; Sauerwein, W; Wittig, A1
Batistoni, DA; Gautier, EA; Gettar, RT; Jiménez Rebagliati, R; Roberti, MJ1
Asano, T; Hattori, Y; Kirihata, M; Kondoh, H; Kurihara, K; Wakamiya, T; Yamaguchi, Y1
Barth, RF; Chandra, S; Lorey, DR; Tjarks, W1
Nakamura, H1
Albritton, JR; Auterinen, I; Binns, PJ; Harling, OK; Kiger, WS; Marek, M; Moss, RL; Nievaart, VA; Rezaei, A; Riley, KJ; Savolainen, S; Seppälä, T; Sköld, K; Viererbl, L1
Chi, CW; Chou, FI; Chung, HP; Liu, HM; Lui, WY1
Bumaschny, E; Cardoso, J; Heber, E; Itoiz, M; Liberman, S; Monti Hughes, A; Nievas, S; Pereira, M; Pozzi, E; Sanchez, P; Schwint, A; Trivillin, V1
Fujimoto, T; Fukumori, Y; Ichikawa, H; Taniguchi, E1
Bet, P; Hilken, G; Huiskamp, R; Kriegeskotte, C; Moss, RL; Sauerwein, WA; Scherag, A; Wittig, A1
García-Reiriz, A; Líberman, S; Magallanes, J; Zupan, J1
Hattori, T; Ishikawa, A; Ohki, H; Saito, K; Yabe, T; Yoshino, K1
Ahmad, T; Barth, RF; Chandra, S; Kabalka, GW1
Bernocchi, G; Coccini, T; Nion, S; Roda, E1
Canella, L; Kudejova, P; Röhrmoser, A; Schmid, E; Schmid, TE; Wagner, FM1
Hagiwara, K; Hamase, K; Kanai, Y; Kato, I; Miyoshi, Y; Nagamori, S; Ohgaki, R; Wei, L; Wiriyasermkul, P; Wongthai, P1
Hattori, Y; Ishimura, M; Kirihata, M; Ohta, Y; Ono, K; Takenaka, H; Tanaka, H; Watanabe, T1
Ai, HW; Borchardt, D; Chen, ZJ; Ji, A; Jiang, DE; Kallio, K; Oleson, AL; Remington, SJ; Tian, Z1
Date, H; Fukunaga, H; Matsuya, Y; Omura, M1
Fukuda, H; Hiratsuka, J1
Hayashi, T; Kashino, G; Kinashi, Y; Masunaga, SI; Ono, K; Suzuki, M; Tanaka, H; Uehara, K; Watanabe, T; Yoshikawa, T1

Reviews

3 review(s) available for 4-boronophenylalanine and boron

ArticleYear
A post melanosomal era: control of melanogenesis and melanoma growth.
    Pigment cell research, 1992, Volume: Suppl 2

    Topics: Adolescent; Animals; Boron; Boron Compounds; Cricetinae; Fatty Acids, Unsaturated; Gene Expression Regulation, Neoplastic; Hair Color; Humans; Infant, Newborn; Isotopes; Male; Melanins; Melanocytes; Melanoma; Melanoma, Experimental; Models, Biological; Monophenol Monooxygenase; Neoplasm Proteins; Neutrons; Phenylalanine; Pigmentation Disorders; Protein Processing, Post-Translational; Pyrones; Radiation-Sensitizing Agents; Skin Pigmentation; Subcellular Fractions; Swine

1992
[Boron delivery system for neutron capture therapy of cancer].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2008, Volume: 49, Issue:5

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Drug Delivery Systems; Humans; Liposomes; Neoplasms; Phenylalanine; Positron-Emission Tomography

2008
Pharmacokinetics of
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 166

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioblastoma; Humans; Isotopes; Melanoma; Neoplasms; Phenylalanine; Positron-Emission Tomography

2020

Trials

3 trial(s) available for 4-boronophenylalanine and boron

ArticleYear
Boron neutron-capture therapy (BNCT) for glioblastoma multiforme (GBM) using the epithermal neutron beam at the Brookhaven National Laboratory.
    International journal of radiation oncology, biology, physics, 1998, Mar-01, Volume: 40, Issue:4

    Topics: Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Dose-Response Relationship, Radiation; Feasibility Studies; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Treatment Outcome

1998
A pharmacokinetic model for the concentration of 10B in blood after boronophenylalanine-fructose administration in humans.
    Radiation research, 2001, Volume: 155, Issue:4

    Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fructose; Glioblastoma; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Models, Biological; Phenylalanine; Skin Neoplasms

2001
Boron biodistribution study in colorectal liver metastases patients in Argentina.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Adenocarcinoma; Aged; Argentina; Boron; Boron Compounds; Boron Neutron Capture Therapy; Colorectal Neoplasms; Female; Humans; In Vitro Techniques; Infusions, Intravenous; Isotopes; Liver; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Tissue Distribution; Transplantation, Autologous

2009

Other Studies

48 other study(ies) available for 4-boronophenylalanine and boron

ArticleYear
In vitro radiobiological analysis of 10B-L-BPA for BNCT of malignant melanoma: correlation of determined 10B-content and cell killing effect.
    Pigment cell research, 1992, Volume: Suppl 2

    Topics: Animals; Boron; Boron Compounds; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Isotopes; Mass Spectrometry; Melanoma, Experimental; Mice; Neutrons; Phenylalanine; Radiation-Sensitizing Agents; Tumor Cells, Cultured

1992
Boron neutron capture therapy of anterior chamber melanoma with p-boronophenylalanine.
    Investigative ophthalmology & visual science, 1992, Volume: 33, Issue:2

    Topics: Administration, Oral; Animals; Anterior Chamber; Autoradiography; Boron; Boron Compounds; Disease Models, Animal; Eye Neoplasms; Isotopes; Melanoma, Experimental; Neutrons; Phenylalanine; Rabbits; Radiation-Sensitizing Agents

1992
In situ detection of cutaneous melanoma by prompt gamma-ray spectrometry using melanoma-seeking 10B-dopa analogue.
    Journal of dermatological science, 1990, Volume: 1, Issue:1

    Topics: Aged; Animals; Boron; Boron Compounds; Cricetinae; Disease Models, Animal; Female; Humans; Isotopes; Male; Melanoma; Mesocricetus; Phenylalanine; Skin Neoplasms; Spectrometry, Gamma; Time Factors

1990
Experimental boron neutron capture therapy for melanoma: systemic delivery of boron to melanotic and amelanotic melanoma.
    Pigment cell research, 1990, Volume: 3, Issue:6

    Topics: Animals; Boron; Boron Compounds; Eye Neoplasms; Isotopes; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neutrons; Phenylalanine; Rabbits; Radiation-Sensitizing Agents; Transplantation, Heterologous

1990
Boron neutron capture therapy for cancer.
    Scientific American, 1990, Volume: 263, Issue:4

    Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Boron; Boron Compounds; Brain Neoplasms; Glioblastoma; Humans; Immunotoxins; Isotopes; Melanoma; Mice; Neoplasms; Neutrons; Phenylalanine; Radiation Dosage

1990
[Selective affinity of 10B1-paraboronophenylalanine-HCl to malignant melanoma: thermal neutron capture therapy].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1983, Volume: 93, Issue:7

    Topics: Animals; Boron; Boron Compounds; Cricetinae; Isotopes; Melanoma; Neoplasms, Experimental; Neutrons; Phenylalanine; Skin; Skin Neoplasms; Spectrometry, Gamma

1983
Response of the central nervous system to boron neutron capture irradiation: evaluation using rat spinal cord model.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1994, Volume: 32, Issue:3

    Topics: Absorption; Animals; Blood-Brain Barrier; Borohydrides; Boron; Boron Compounds; Boron Neutron Capture Therapy; Disease Models, Animal; Dose-Response Relationship, Radiation; Isotopes; Linear Energy Transfer; Male; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rats; Rats, Inbred F344; Relative Biological Effectiveness; Spinal Cord; Spinal Cord Diseases; Sulfhydryl Compounds

1994
Effect of L-10B-p-boronophenylalanine-fructose and the boron neutron capture reaction on mouse brain dopaminergic neurons.
    Cancer research, 1995, Feb-15, Volume: 55, Issue:4

    Topics: Animals; Blood-Brain Barrier; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain; Dopamine; Fructose; Immunohistochemistry; Isotopes; Male; Mice; Mice, Inbred BALB C; Nerve Fibers; Neurons; Phenylalanine; Radiation-Sensitizing Agents

1995
Selective boron accumulation in human ocular melanoma vs surrounding eye components after 10B1-p-boronophenylalanine administration. Prerequisite for clinical trial of neutron-capture therapy.
    Melanoma research, 1994, Volume: 4, Issue:3

    Topics: Boron; Boron Compounds; Clinical Trials as Topic; Eye Neoplasms; Humans; Isotopes; Mass Spectrometry; Melanoma; Neutron Capture Therapy; Phenylalanine; Radiation-Sensitizing Agents

1994
Subcellular localization of p-boronophenylalanine-delivered boron-10 in the rat 9L gliosarcoma: cryogenic preparation in vitro and in vivo.
    Radiation research, 1994, Volume: 140, Issue:1

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Gliosarcoma; Isotopes; Phenylalanine; Rats; Tumor Cells, Cultured

1994
Response of rat skin to boron neutron capture therapy with p-boronophenylalanine or borocaptate sodium.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1994, Volume: 32, Issue:2

    Topics: Administration, Oral; Animals; Borohydrides; Boron; Boron Compounds; Boron Neutron Capture Therapy; Dose-Response Relationship, Radiation; Endothelium, Vascular; Injections, Intravenous; Isotopes; Male; Phenylalanine; Radiation Dosage; Radiation Injuries, Experimental; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Relative Biological Effectiveness; Skin; Skin Diseases; Spectrometry, Gamma; Sulfhydryl Compounds; Wound Healing

1994
Preloading with L-tyrosine increases the uptake of boronophenylalanine in mouse melanoma cells.
    Cancer research, 1994, Dec-15, Volume: 54, Issue:24

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Melanoma; Mice; Phenylalanine; Radiation-Sensitizing Agents; Time Factors; Tumor Cells, Cultured; Tyrosine

1994
The pharmacokinetics of p-Boronophenylalanine.fructose in human patients with glioma and metastatic melanoma.
    International journal of radiation oncology, biology, physics, 1994, Mar-30, Volume: 28, Issue:5

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioma; Humans; Melanoma; Phenylalanine; Radiation-Sensitizing Agents

1994
Boron neutron capture therapy of intracerebral melanoma using boronophenylalanine as a capture agent.
    Cancer research, 1993, Jul-15, Volume: 53, Issue:14

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Cell Survival; Humans; Male; Melanoma; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rats; Rats, Nude; Tissue Distribution

1993
Accumulation of boron in malignant and normal cells incubated in vitro with boronophenylalanine, mercaptoborane or boric acid.
    Radiation research, 1996, Volume: 146, Issue:5

    Topics: Animals; Boric Acids; Boron; Boron Compounds; Boron Neutron Capture Therapy; Humans; Mice; Phenylalanine; Tumor Cells, Cultured

1996
Biodistribution of boronophenylalanine in patients with glioblastoma multiforme: boron concentration correlates with tumor cellularity.
    Radiation research, 1998, Volume: 149, Issue:2

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Glioblastoma; Humans; Phenylalanine; Tissue Distribution

1998
Responses of total and quiescent cell populations in solid tumors to boron and gadolinium neutron capture reaction using neutrons with two different energy spectra.
    Japanese journal of cancer research : Gann, 1998, Volume: 89, Issue:1

    Topics: Animals; Borohydrides; Boron; Boron Compounds; Boron Neutron Capture Therapy; Bromodeoxyuridine; Cadmium Radioisotopes; Carcinoma, Squamous Cell; Contrast Media; Cytochalasin B; Dose-Response Relationship, Radiation; Female; Fluorescent Antibody Technique, Indirect; Gadolinium; Gadolinium DTPA; Injections, Intraperitoneal; Isotopes; Mice; Mice, Inbred C3H; Micronucleus Tests; Neoplasm Transplantation; Phenylalanine; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Tumor Cells, Cultured

1998
Positron emission tomography-based boron neutron capture therapy using boronophenylalanine for high-grade gliomas: part I.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:8

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Fluorine Radioisotopes; Glioma; Humans; Isotopes; Phenylalanine; Radiation-Sensitizing Agents; Tomography, Emission-Computed

1998
Positron emission tomography-based boron neutron capture therapy using boronophenylalanine for high-grade gliomas: part II.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:8

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Fluorine Radioisotopes; Glioma; Humans; Isotopes; Mathematical Computing; Phenylalanine; Radiation-Sensitizing Agents; Tomography, Emission-Computed

1998
Biodistribution of boron concentration on melanoma-bearing hamsters after administration of p-, m-, o-boronophenylalanine.
    Japanese journal of cancer research : Gann, 2000, Volume: 91, Issue:4

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Cricetinae; Male; Melanins; Melanoma, Experimental; Mesocricetus; Mice; Phenylalanine; Radiation-Sensitizing Agents; Tissue Distribution

2000
Boron neutron capture therapy of a murine mammary carcinoma using a lipophilic carboranyltetraphenylporphyrin.
    Radiation research, 2001, Volume: 155, Issue:4

    Topics: Animals; Borohydrides; Boron; Boron Compounds; Boron Neutron Capture Therapy; Drug Carriers; Female; Hindlimb; Hydrophobic and Hydrophilic Interactions; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Phenylalanine; Sulfhydryl Compounds; Thorax; Tissue Distribution

2001
Evaluation of the genotoxic effects of the boron neutron capture reaction in human melanoma cells using the cytokinesis block micronucleus assay.
    Mutagenesis, 2001, Volume: 16, Issue:5

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Cell Division; Cell Line; Cells, Cultured; Cricetinae; Drug Carriers; Fast Neutrons; Humans; Isotopes; Melanoma; Micronucleus Tests; Phenylalanine; Radiation-Sensitizing Agents; Tumor Cells, Cultured

2001
Quantitative imaging and microlocalization of boron-10 in brain tumors and infiltrating tumor cells by SIMS ion microscopy: relevance to neutron capture therapy.
    Cancer research, 2001, Nov-15, Volume: 61, Issue:22

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Drug Administration Schedule; Gliosarcoma; Infusions, Intravenous; Isotopes; Male; Phenylalanine; Rats; Rats, Inbred F344; Spectrometry, Mass, Secondary Ion

2001
The hamster cheek pouch as a model of oral cancer for boron neutron capture therapy studies: selective delivery of boron by boronophenylalanine.
    Cancer research, 2001, Dec-15, Volume: 61, Issue:24

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Carcinogens; Cheek; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Mesocricetus; Mouth Neoplasms; Phenylalanine; Radiation-Sensitizing Agents; Tissue Distribution

2001
Effect of boron neutron capture therapy for melanotic and amelanotic melanoma transplanted into mouse brain.
    Pigment cell research, 2002, Volume: 15, Issue:1

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Isotopes; Melanins; Melanoma, Amelanotic; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Phenylalanine; Radiation-Sensitizing Agents; Tumor Cells, Cultured

2002
Selective uptake of p-borophenylalanine by undifferentiated thyroid carcinoma for boron neutron capture therapy.
    Thyroid : official journal of the American Thyroid Association, 2002, Volume: 12, Issue:1

    Topics: Adenoma; Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Cattle; Cell Division; Cells, Cultured; Humans; Isotopes; Kinetics; Mice; Mice, Nude; Neoplasm Transplantation; Phenylalanine; Radiation-Sensitizing Agents; Thyroid Gland; Thyroid Neoplasms; Tumor Cells, Cultured

2002
Imaging of fluorine and boron from fluorinated boronophenylalanine in the same cell at organelle resolution by correlative ion microscopy and confocal laser scanning microscopy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:8

    Topics: Boron; Boron Compounds; Brain Neoplasms; Fluorine; Glioblastoma; Humans; Image Processing, Computer-Assisted; Ions; Microscopy, Confocal; Mitochondria; Models, Chemical; Phenylalanine; Radiation-Sensitizing Agents; Time Factors; Tomography, Emission-Computed; Tumor Cells, Cultured

2002
The enhancement of neutron irradiation of HeLa-S cervix carcinoma cells by cell-nucleus-addressed deca-p-boronophenylalanine.
    European journal of medicinal chemistry, 2003, Volume: 38, Issue:6

    Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Boron; Boron Compounds; Boron Neutron Capture Therapy; Carcinoma; Cell Nucleus; Cell Survival; Female; Flow Cytometry; HeLa Cells; Humans; Mass Spectrometry; Microscopy, Confocal; Molecular Sequence Data; Phenylalanine; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

2003
Delivery of (10)boron to oral squamous cell carcinoma using boronophenylalanine and borocaptate sodium for boron neutron capture therapy.
    Oral oncology, 2004, Volume: 40, Issue:5

    Topics: Animals; Borohydrides; Boron; Boron Compounds; Boron Neutron Capture Therapy; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Female; Isotopes; Mice; Mice, Nude; Mouth Neoplasms; Phenylalanine; Relative Biological Effectiveness; Sulfhydryl Compounds

2004
Approach to magnetic neutron capture therapy.
    International journal of radiation oncology, biology, physics, 2005, Nov-01, Volume: 63, Issue:3

    Topics: Boron; Boron Compounds; Carbon; Drug Carriers; Iron; Magnetics; Nanotechnology; Neutron Capture Therapy; Phenylalanine

2005
Analysis of 10B antitumoral compounds by means of flow-injection into ESI-MS/MS.
    Journal of mass spectrometry : JMS, 2005, Volume: 40, Issue:12

    Topics: Adult; Borohydrides; Boron; Boron Compounds; Boron Neutron Capture Therapy; Clinical Trials, Phase I as Topic; Humans; Isotopes; Middle Aged; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds

2005
Assessment of chemical purity of 10B-enriched p-boronophenylalanine by high-performance liquid chromatography coupled on-line with inductively coupled plasma optical emission spectrometry.
    Analytical and bioanalytical chemistry, 2007, Volume: 388, Issue:2

    Topics: Boron; Boron Compounds; Buffers; Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Phenylalanine; Radiation-Sensitizing Agents; Spectrophotometry; Spectrophotometry, Ultraviolet; Tyrosine

2007
Biological evaluation of fluorinated p-boronophenylalanine derivatives as a boron carrier.
    Protein and peptide letters, 2007, Volume: 14, Issue:3

    Topics: Animals; Antineoplastic Agents; Boron; Boron Compounds; Cell Survival; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Glioma; Hydrocarbons, Fluorinated; Ion Transport; Models, Biological; Phenylalanine; Rats; Solubility; Tumor Cells, Cultured

2007
Quantitative subcellular imaging of boron compounds in individual mitotic and interphase human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS).
    Journal of microscopy, 2008, Volume: 229, Issue:Pt 1

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line; Glioblastoma; Humans; Interphase; Mitosis; Phenylalanine; Spectrometry, Mass, Secondary Ion

2008
An international dosimetry exchange for BNCT part II: computational dosimetry normalizations.
    Medical physics, 2008, Volume: 35, Issue:12

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Clinical Trials as Topic; Humans; Isotopes; Neoplasms; Phantoms, Imaging; Phenylalanine; Radiation-Sensitizing Agents; Radiometry; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Reproducibility of Results; Software; Treatment Outcome

2008
Suitability of boron carriers for BNCT: accumulation of boron in malignant and normal liver cells after treatment with BPA, BSH and BA.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Animals; Boric Acids; Borohydrides; Boron; Boron Compounds; Boron Neutron Capture Therapy; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Clone Cells; Hepatocytes; Humans; Liver Neoplasms; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Tissue Distribution

2009
Biodistribution of BPA and BSH after single, repeated and simultaneous administrations for neutron-capture therapy of cancer.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Animals; Borohydrides; Boron; Boron Compounds; Boron Neutron Capture Therapy; Cricetinae; Female; Isotopes; Melanoma, Experimental; Mesocricetus; Phenylalanine; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Tissue Distribution

2009
Biodistribution of (10)B for Boron Neutron Capture Therapy (BNCT) in a mouse model after injection of sodium mercaptoundecahydro-closo-dodecaborate and l-para-boronophenylalanine.
    Radiation research, 2009, Volume: 172, Issue:4

    Topics: Animals; Borohydrides; Boron; Boron Compounds; Boron Neutron Capture Therapy; Drug Therapy, Combination; Injections; Isotopes; Male; Mice; Organ Specificity; Phenylalanine; Sulfhydryl Compounds; Tissue Distribution

2009
Artificial neural networks to evaluate the boron concentration decreasing profile in blood-BPA samples of BNCT patients.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2011, Volume: 69, Issue:12

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Humans; Neural Networks, Computer; Phenylalanine

2011
(10)B-NMR determination of (10)B-BPA, (10)B-BPA-fructose complex and total (10)B in blood for BNCT.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

    Topics: Blood Chemical Analysis; Boron; Boron Compounds; Boron Neutron Capture Therapy; Fructose; Humans; Isotopes; Magnetic Resonance Spectroscopy; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity

2014
Quantitative evaluation of boron neutron capture therapy (BNCT) drugs for boron delivery and retention at subcellular-scale resolution in human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS).
    Journal of microscopy, 2014, Volume: 254, Issue:3

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Calcium; Cell Line, Tumor; Cell Tracking; Glioblastoma; Humans; Intracellular Space; Isotopes; Microscopy, Confocal; Phenylalanine; Potassium; Sodium; Spectrometry, Mass, Secondary Ion; Time Factors

2014
Blood-brain barrier (BBB) toxicity and permeability assessment after L-(4-¹⁰Boronophenyl)alanine, a conventional B-containing drug for boron neutron capture therapy, using an in vitro BBB model.
    Brain research, 2014, Oct-02, Volume: 1583

    Topics: Animals; Blood-Brain Barrier; Boron; Boron Compounds; Brain; Capillary Permeability; Cattle; Coculture Techniques; Cytoskeleton; Endothelial Cells; Neuroglia; Occludin; Phenylalanine; Pilot Projects; Rats; Tight Junctions; Vimentin; Zonula Occludens-1 Protein

2014
The effectiveness of the high-LET radiations from the boron neutron capture [10B(n,α) 7Li] reaction determined for induction of chromosome aberrations and apoptosis in lymphocytes of human blood samples.
    Radiation and environmental biophysics, 2015, Volume: 54, Issue:1

    Topics: Apoptosis; Borohydrides; Boron; Boron Compounds; Boron Neutron Capture Therapy; Chromosome Aberrations; Dose-Response Relationship, Radiation; Female; Humans; Isotopes; Linear Energy Transfer; Lithium; Lymphocytes; Male; Neutrons; Phenylalanine; Radiation-Sensitizing Agents; Sulfhydryl Compounds

2015
Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2.
    Cancer science, 2015, Volume: 106, Issue:3

    Topics: Amino Acid Transport System y+; Amino Acid Transport System y+L; Amino Acid Transport Systems; Animals; Biological Transport; Boron; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Fusion Regulatory Protein 1, Light Chains; HeLa Cells; Humans; MCF-7 Cells; Neurotransmitter Transport Proteins; Oocytes; Phenylalanine; RNA Interference; RNA, Small Interfering; Xenopus

2015
Detection of boronic acid derivatives in cells using a fluorescent sensor.
    Organic & biomolecular chemistry, 2015, Jul-07, Volume: 13, Issue:25

    Topics: Antineoplastic Agents; Boron; Boron Compounds; Boronic Acids; Bortezomib; Cell Line, Tumor; Chelating Agents; Fluorescent Dyes; Humans; Optical Imaging; Phenylalanine; Spectrometry, Fluorescence

2015
The N-B Interaction through a Water Bridge: Understanding the Chemoselectivity of a Fluorescent Protein Based Probe for Peroxynitrite.
    Journal of the American Chemical Society, 2016, Apr-13, Volume: 138, Issue:14

    Topics: Amino Acid Sequence; Boron; Boron Compounds; Crystallography, X-Ray; Fluorescent Dyes; Green Fluorescent Proteins; Hydrogen Peroxide; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Peroxynitrous Acid; Phenylalanine; Sequence Alignment; Spectrometry, Fluorescence; Water

2016
A Model for Estimating Dose-Rate Effects on Cell-Killing of Human Melanoma after Boron Neutron Capture Therapy.
    Cells, 2020, 04-30, Volume: 9, Issue:5

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Cell Death; Cell Line, Tumor; Cell Survival; Cobalt Radioisotopes; Computer Simulation; Dose-Response Relationship, Radiation; Gamma Rays; Humans; Isotopes; Melanoma; Models, Biological; Monte Carlo Method; Neutrons; Phenylalanine; Radiometry; Relative Biological Effectiveness; Time Factors

2020
Pharmacokinetic Study of
    European journal of drug metabolism and pharmacokinetics, 2023, Volume: 48, Issue:4

    Topics: Animals; Boron; Boron Neutron Capture Therapy; Fructose; Mice; Sorbitol; Treatment Outcome

2023