Page last updated: 2024-09-03

4-borono-2-fluorophenylalanine and phenylalanine

4-borono-2-fluorophenylalanine has been researched along with phenylalanine in 29 studies

Compound Research Comparison

Studies
(4-borono-2-fluorophenylalanine)
Trials
(4-borono-2-fluorophenylalanine)
Recent Studies (post-2010)
(4-borono-2-fluorophenylalanine)
Studies
(phenylalanine)
Trials
(phenylalanine)
Recent Studies (post-2010) (phenylalanine)
2911123,6957214,367

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (27.59)18.2507
2000's10 (34.48)29.6817
2010's10 (34.48)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Hatazawa, J; Honda, C; Ichihashi, M; Ido, T; Ishiwata, K; Kubota, K; Mishima, Y; Shiono, M; Yoshino, K1
Honda, C; Ichihashi, M; Ido, T; Ishiwata, K; Kawamura, M; Mishima, Y1
Ichihashi, M; Ido, T; Ishiwata, K; Kawamura, M; Kubota, K; Mishima, Y1
Ido, T; Ishiwata, K; Kubota, K; Kubota, R; Tada, M; Yamada, S1
Hiratsuka, J; Honda, C; Ido, T; Imahori, Y; Mishima, Y; Ueda, S1
Bailey, SF; Fuhr, JE; Kabalka, GW1
Fujii, R; Ido, T; Imahori, Y; Kusuki, T; Ohmori, Y; Ono, K; Ueda, S1
Fujii, R; Ido, T; Imahori, Y; Kobayashi, T; Kusuki, T; Ohmori, Y; Ono, K; Sakae, K; Takagaki, M; Ueda, S1
Imahori, Y; Mineura, K; Takahashi, Y1
Chang, PF; Chen, FD; Chen, JC; Deng, WP; Hwang, JJ; Lee, JS; Liao, AH; Liu, RS; Wang, HE1
Chang, SM; Chen, JC; Hsu, FY; Liu, RS; Wang, HE1
Imahori, Y; Mineura, K; Sasajima, H1
Chang, CW; Chen, FD; Chen, JC; Chen, YF; Hsieh, CH; Hwang, JJ; Kai, JJ; Liu, RS; Wang, HE1
Eskola, O; Havu-Aurén, K; Jääskeläinen, J; Kiiski, J; Kulvik, M; Lehtiö, K; Minn, H; Oikonen, V; Vähätalo, J; Vuorinen, V1
Campanella, R; Capuani, S; D'Amore, E; Fasano, F; La Bella, A; Lecce, M; Maraviglia, B; Migneco, LM; Pastore, FS; Porcari, P1
Inaji, M; Ishii, K; Ishiwata, K; Kimura, Y; Matsumura, A; Momose, T; Nariai, T; Ohno, K; Yamamoto, T1
Ariyoshi, Y; Kawabata, S; Kimura, Y; Maruhashi, A; Miyatake, S; Ono, K; Shimahara, M; Suzuki, M1
Altieri, S; Cionini, L; Menichetti, L; Minn, H; Salvadori, PA; Sauerwein, WA; Solin, O1
Chang, CW; Chou, FI; Hsiao, MC; Hwang, JJ; Lin, YC; Wang, SJ; Yang, BH1
Arai, Y; Fujii, H; Honda, N; Itami, J; Kawai, K; Kurihara, H; Ohe, K; Yoshimoto, M1
Arai, Y; Hiroi, K; Honda, N; Itami, J; Kono, Y; Kumita, S; Kurihara, H; Murakami, R; Tani, H; Yoshimoto, M1
Kuntner, C; Langer, O; Mairinger, S; Stanek, J; Wanek, T1
Yoshimoto, M1
Hatazawa, J; Horitsugi, G; Isohashi, K; Naka, S; Shimosegawa, E1
Blaickner, M; Filip, T; Grunewald, C; Kudejova, P; Kuntner, C; Langer, O; Mairinger, S; Rollet, S; Sauberer, M; Schütz, C; Stanek, J; Wanek, T1
Fujii, H; Hiroi, K; Honda, N; Itami, J; Ito, M; Kurihara, H; Nakamura, S; Shikano, N; Yoshimoto, M1
Ishiwata, K1
Aoki, M; Hatazawa, J; Horitsugi, G; Ikeda, H; Kanai, Y; Kongpracha, P; Nagamori, S; Naka, S; Shimosegawa, E; Watabe, T1
Chen, YL; Chen, YW; Hu, YS; Huang, WS; Lee, JC; Li, CY; Lin, CS; Lin, KH; Lo, YW1

Reviews

3 review(s) available for 4-borono-2-fluorophenylalanine and phenylalanine

ArticleYear
[Molecular imaging for brain tumor using positron emission tomography].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Amino Acids; Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Carbon Radioisotopes; Cell Proliferation; Diglycerides; Electrons; Fluorine Radioisotopes; Humans; Neoplasm Staging; Oligodeoxyribonucleotides, Antisense; Phenylalanine; Phospholipids; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; RNA, Messenger

2005
[Current Status and Prospects on PET Radiopharmaceuticals for Radiotherapy].
    Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics, 2015, Volume: 35, Issue:1

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Coordination Complexes; Fluorine Radioisotopes; Humans; Hypoxia; Misonidazole; Neoplasms; Nitroimidazoles; Organometallic Compounds; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Thiosemicarbazones

2015
4-Borono-2-
    Annals of nuclear medicine, 2019, Volume: 33, Issue:4

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Humans; Phenylalanine; Positron-Emission Tomography; Radiochemistry

2019

Trials

1 trial(s) available for 4-borono-2-fluorophenylalanine and phenylalanine

ArticleYear
Assessment of
    Annals of nuclear medicine, 2016, Volume: 30, Issue:10

    Topics: Adult; Boron; Boron Compounds; Boron Neutron Capture Therapy; Female; Healthy Volunteers; Humans; Isotopes; Male; Middle Aged; Phenylalanine; Positron-Emission Tomography; Radiotherapy Dosage; Radiotherapy, Image-Guided; Tissue Distribution; Young Adult

2016

Other Studies

25 other study(ies) available for 4-borono-2-fluorophenylalanine and phenylalanine

ArticleYear
A unique in vivo assessment of 4-[10B]borono-L-phenylalanine in tumour tissues for boron neutron capture therapy of malignant melanomas using positron emission tomography and 4-borono-2-[18F]fluoro-L-phenylalanine.
    Melanoma research, 1992, Volume: 2, Issue:3

    Topics: Animals; Boron Compounds; Cricetinae; Fluorine Radioisotopes; Melanoma, Experimental; Mesocricetus; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neutron Capture Therapy; Phenylalanine; Tissue Distribution; Tomography, Emission-Computed

1992
4-Borono-2-[18F]fluoro-D,L-phenylalanine: a possible tracer for melanoma diagnosis with PET.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1992, Volume: 19, Issue:3

    Topics: Animals; Autoradiography; Boron Compounds; Carbon Radioisotopes; Cricetinae; Deoxyglucose; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Melanoma, Experimental; Mesocricetus; Mice; Neoplasm Transplantation; Phenylalanine; Tissue Distribution; Tomography, Emission-Computed; Tumor Cells, Cultured; Whole-Body Counting

1992
4-Borono-2-[18F]fluoro-D,L-phenylalanine as a target compound for boron neutron capture therapy: tumor imaging potential with positron emission tomography.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1991, Volume: 18, Issue:7

    Topics: Animals; Autoradiography; Boron Compounds; Chromatography, High Pressure Liquid; Fluorine Radioisotopes; Male; Mammary Neoplasms, Experimental; Mice; Phenylalanine; Tomography, Emission-Computed

1991
Cellular accumulation of 18F-labelled boronophenylalanine depending on DNA synthesis and melanin incorporation: a double-tracer microautoradiographic study of B16 melanomas in vivo.
    British journal of cancer, 1993, Volume: 67, Issue:4

    Topics: Animals; Autoradiography; Boron Compounds; Boron Neutron Capture Therapy; Cell Division; Disease Models, Animal; DNA, Neoplasm; Fluorine Radioisotopes; Male; Melanins; Melanoma, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasm Transplantation; Phenylalanine; Pigmentation; Radionuclide Imaging

1993
In vivo diagnosis of human malignant melanoma with positron emission tomography using specific melanoma-seeking 18F-DOPA analogue.
    Journal of neuro-oncology, 1997, Volume: 33, Issue:1-2

    Topics: Boron; Boron Compounds; Brain; Brain Neoplasms; Fluorine Radioisotopes; Humans; Isotopes; Lymphatic Metastasis; Melanoma; Phenylalanine; Tomography, Emission-Computed

1997
In vitro effects of boron-containing compounds upon glioblastoma cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1997, Volume: 216, Issue:3

    Topics: Boron Compounds; Boron Neutron Capture Therapy; Bromodeoxyuridine; Cell Cycle; Cell Division; DNA Replication; Flow Cytometry; Fluorine Radioisotopes; Fructose; Glioblastoma; Humans; Phenylalanine; Tumor Cells, Cultured

1997
Fluorine-18-labeled fluoroboronophenylalanine PET in patients with glioma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:2

    Topics: Astrocytoma; Boron Compounds; Brain Neoplasms; Cerebrovascular Circulation; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Phenylalanine; Radiopharmaceuticals; Tomography, Emission-Computed

1998
Positron emission tomography-based boron neutron capture therapy using boronophenylalanine for high-grade gliomas: part II.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:8

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Fluorine Radioisotopes; Glioma; Humans; Isotopes; Mathematical Computing; Phenylalanine; Radiation-Sensitizing Agents; Tomography, Emission-Computed

1998
Prognostic and therapeutic indicator of fluoroboronophenylalanine positron emission tomography in patients with gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Dec-01, Volume: 9, Issue:16 Pt 1

    Topics: Adult; Aged; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fluorine Radioisotopes; Glioma; Humans; Male; Middle Aged; Phenylalanine; Prognosis; Survival Rate; Tomography, Emission-Computed; Treatment Outcome

2003
Evaluation of 4-borono-2-18F-fluoro-L-phenylalanine-fructose as a probe for boron neutron capture therapy in a glioma-bearing rat model.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:2

    Topics: Animals; Autoradiography; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Fluorine Radioisotopes; Fructose; Glioma; Male; Phenylalanine; Rats; Rats, Inbred F344; Tissue Distribution; Tomography, Emission-Computed

2004
MicroPET-based pharmacokinetic analysis of the radiolabeled boron compound [18F]FBPA-F in rats with F98 glioma.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2004, Volume: 61, Issue:5

    Topics: Animals; Boron Compounds; Brain Neoplasms; Fluorine Radioisotopes; Fructose; Glioma; Humans; Male; Phenylalanine; Positron-Emission Tomography; Rats; Rats, Inbred F344

2004
Evaluation of pharmacokinetics of 4-borono-2-(18)F-fluoro-L-phenylalanine for boron neutron capture therapy in a glioma-bearing rat model with hyperosmolar blood-brain barrier disruption.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:11

    Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Evaluation, Preclinical; Glioma; Injections, Intra-Arterial; Male; Mannitol; Metabolic Clearance Rate; Organ Specificity; Osmolar Concentration; Phenylalanine; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Inbred F344; Tissue Distribution

2005
Uptake of 4-borono-2-[18F]fluoro-L-phenylalanine in sporadic and neurofibromatosis 2-related schwannoma and meningioma studied with PET.
    European journal of nuclear medicine and molecular imaging, 2007, Volume: 34, Issue:1

    Topics: Adult; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neurilemmoma; Neurofibromatoses; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals

2007
In vivo 19F MR imaging and spectroscopy for the BNCT optimization.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Fluorine; Glioma; In Vitro Techniques; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Wistar; Tissue Distribution

2009
PET pharmacokinetic analysis to estimate boron concentration in tumor and brain as a guide to plan BNCT for malignant cerebral glioma.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Algorithms; Astrocytoma; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Carbon Radioisotopes; Glioblastoma; Glioma; Humans; Methionine; Phenylalanine; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted

2009
Boron neutron capture therapy for recurrent oral cancer and metastasis of cervical lymph node.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Boron Compounds; Boron Neutron Capture Therapy; Female; Fluorine Radioisotopes; Humans; Lymphatic Metastasis; Male; Middle Aged; Mouth Neoplasms; Neck; Neoplasm Recurrence, Local; Pain; Phenylalanine; Positron-Emission Tomography; Quality of Life; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tomography, X-Ray Computed

2009
Positron emission tomography and [18F]BPA: a perspective application to assess tumour extraction of boron in BNCT.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Fluorine Radioisotopes; Humans; Isotopes; Lymphatic Metastasis; Melanoma; Models, Biological; Neoplasms; Phenylalanine; Positron-Emission Tomography; Prognosis; Radiation-Sensitizing Agents; Tomography, X-Ray Computed

2009
Macro- and microdistributions of boron drug for boron neutron capture therapy in an animal model.
    Anticancer research, 2012, Volume: 32, Issue:7

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Fluorine Radioisotopes; Fructose; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Phenylalanine; Positron-Emission Tomography; Xenograft Model Antitumor Assays

2012
Predominant contribution of L-type amino acid transporter to 4-borono-2-(18)F-fluoro-phenylalanine uptake in human glioblastoma cells.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:5

    Topics: Amino Acid Transport Systems; Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Methionine; Phenylalanine; Positron-Emission Tomography

2013
Correlation of (18)F-BPA and (18)F-FDG uptake in head and neck cancers.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 113, Issue:2

    Topics: Adult; Aged; Boron Compounds; Boron Neutron Capture Therapy; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Male; Middle Aged; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals

2014
Automated electrophilic radiosynthesis of [¹⁸F]FBPA using a modified nucleophilic GE TRACERlab FXFDG.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2015, Volume: 104

    Topics: Boron Compounds; Electron Transport; Electrons; Equipment Design; Equipment Failure Analysis; Fluorine Radioisotopes; Isotope Labeling; Materials Testing; Phenylalanine; Radiopharmaceuticals; Robotics

2015
On the applicability of [
    Nuclear medicine and biology, 2017, Volume: 44

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Female; Humans; Liver Neoplasms; Mice; Phenylalanine; Positron-Emission Tomography

2017
Non-invasive estimation of
    Cancer science, 2018, Volume: 109, Issue:5

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Female; Humans; Infusions, Intravenous; Mice; Mice, Inbred BALB C; Phenylalanine; Positron-Emission Tomography; Tissue Distribution

2018
Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft models of C6 glioma and MIA PaCa-2.
    Annals of nuclear medicine, 2019, Volume: 33, Issue:6

    Topics: Animals; Blood Circulation; Boron Compounds; Cell Line, Tumor; Cell Transformation, Neoplastic; Glioma; Humans; Large Neutral Amino Acid-Transporter 1; Male; Pancreatic Neoplasms; Phenylalanine; Positron-Emission Tomography; Radioactive Tracers; Radiopharmaceuticals; Rats; Tissue Distribution; Tyrosine

2019
The importance of optimal ROIs delineation for FBPA-PET before BNCT.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 163

    Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Feasibility Studies; Humans; Phenylalanine; Positron-Emission Tomography

2020