4-azidophenylalanine and propargyl-alcohol

4-azidophenylalanine has been researched along with propargyl-alcohol* in 1 studies

Other Studies

1 other study(ies) available for 4-azidophenylalanine and propargyl-alcohol

Article	Year
Enhancement of Binding Affinity of Folate to Its Receptor by Peptide Conjugation. International journal of molecular sciences, 2019, Apr-30, Volume: 20, Issue:9 (1) Background: The folate receptor (FR) is a target for cancer treatment and detection. Expression of the FR is restricted in normal cells but overexpressed in many types of tumors. Folate was conjugated with peptides for enhancing binding affinity to the FR. (2) Materials and Methods: For conjugation, folate was coupled with propargyl or dibenzocyclooctyne, and 4-azidophenylalanine was introduced in peptides for "click" reactions. We measured binding kinetics including the rate constants of association ( Topics: Alkynes; Azides; Click Chemistry; Cyclooctanes; Folate Receptors, GPI-Anchored; Folic Acid; Molecular Docking Simulation; Peptides; Phenylalanine; Propanols; Protein Binding	2019

Article

Year

Enhancement of Binding Affinity of Folate to Its Receptor by Peptide Conjugation.

International journal of molecular sciences, 2019, Apr-30, Volume: 20, Issue:9

(1) Background: The folate receptor (FR) is a target for cancer treatment and detection. Expression of the FR is restricted in normal cells but overexpressed in many types of tumors. Folate was conjugated with peptides for enhancing binding affinity to the FR. (2) Materials and Methods: For conjugation, folate was coupled with propargyl or dibenzocyclooctyne, and 4-azidophenylalanine was introduced in peptides for "click" reactions. We measured binding kinetics including the rate constants of association (

Topics: Alkynes; Azides; Click Chemistry; Cyclooctanes; Folate Receptors, GPI-Anchored; Folic Acid; Molecular Docking Simulation; Peptides; Phenylalanine; Propanols; Protein Binding

2019