Page last updated: 2024-09-04

4-androstene-3,17-diol and norethindrone

4-androstene-3,17-diol has been researched along with norethindrone in 2 studies

Compound Research Comparison

Studies (4-androstene-3,17-diol)	Trials (4-androstene-3,17-diol)	Recent Studies (post-2010) (4-androstene-3,17-diol)	Studies (norethindrone)	Trials (norethindrone)	Recent Studies (post-2010) (norethindrone)
13	1	2	4,295	884	303

Protein Interaction Comparison

Protein	Taxonomy	norethindrone (IC50)
Estrogen receptor	Homo sapiens (human)	0.808
Glucocorticoid receptor	Homo sapiens (human)	0.433
Progesterone receptor	Homo sapiens (human)	0.0032
Glycine receptor subunit alpha-1	Rattus norvegicus (Norway rat)	0.433
Androgen receptor	Rattus norvegicus (Norway rat)	0.0711
Glycine receptor subunit beta	Rattus norvegicus (Norway rat)	0.433
Glycine receptor subunit alpha-2	Rattus norvegicus (Norway rat)	0.433
Glycine receptor subunit alpha-3	Rattus norvegicus (Norway rat)	0.433
Sodium-dependent serotonin transporter	Homo sapiens (human)	4.537

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ernst, B; Lill, MA; Vedani, A; Winiger, F	1
Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N	1

Other Studies

2 other study(ies) available for 4-androstene-3,17-diol and norethindrone

Article	Year
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18 Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics	2005
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7 Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids	2008

Article

Year

Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.

Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18

Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics

2005

An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.

Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids

2008