Page last updated: 2024-09-04

4-androstene-3,17-diol and methyltestosterone

4-androstene-3,17-diol has been researched along with methyltestosterone in 2 studies

Compound Research Comparison

Studies (4-androstene-3,17-diol)	Trials (4-androstene-3,17-diol)	Recent Studies (post-2010) (4-androstene-3,17-diol)	Studies (methyltestosterone)	Trials (methyltestosterone)	Recent Studies (post-2010) (methyltestosterone)
13	1	2	1,478	63	165

Protein Interaction Comparison

Protein	Taxonomy	methyltestosterone (IC50)
Glucocorticoid receptor	Homo sapiens (human)	1.843
Glycine receptor subunit alpha-1	Rattus norvegicus (Norway rat)	1.843
Androgen receptor	Rattus norvegicus (Norway rat)	0.0111
Glycine receptor subunit beta	Rattus norvegicus (Norway rat)	1.843
Glycine receptor subunit alpha-2	Rattus norvegicus (Norway rat)	1.843
Glycine receptor subunit alpha-3	Rattus norvegicus (Norway rat)	1.843

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ernst, B; Lill, MA; Vedani, A; Winiger, F	1
Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N	1

Other Studies

2 other study(ies) available for 4-androstene-3,17-diol and methyltestosterone

Article	Year
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18 Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics	2005
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7 Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids	2008

Article

Year

Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.

Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18

Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics

2005

An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.

Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids

2008