Compounds > 4-aminoquinoline
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4-aminoquinoline and heme

4-aminoquinoline has been researched along with heme in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's0 (0.00)29.6817
2010's8 (72.73)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Bray, PG; Hawley, SR; O'Neill, PM; Park, BK; Storr, RC; Ward, SA; Willock, DJ1
Bray, PG; Hawley, SR; O'Neill, PM; Park, BK; Ward, SA1
Haq, W; Katti, SB; Puri, SK; Smilkstein, M; Solomon, VR; Srivastava, K1
Balzarini, J; Bharatam, PV; Chibale, K; Kaur, H; Little, S; Singh, K1
Figueiras, M; Gomes, JR; Gomes, P; Gut, J; Pérez, BC; Rosenthal, PJ; Teixeira, C1
Khan, SI; Kumar, D; Ponnan, P; Rawat, DS; Tekwani, BL1
Bernardino, AMR; Borges, JC; Bourguignon, SC; Calvet, CM; de Araújo, HP; do Nascimento, SB; Lechuga, GC; Motta, MCM; Pereira, MCS; Zuma, AA1
Khan, SI; Ponnan, P; Rawat, DS; Reddy, PL; Tripathi, M1
Bahuguna, A; Khan, SI; Kumar, D; Maurya, SS; Rawat, DS1
Bahuguna, A; Khan, SI; Kholiya, R; Kumar, D; Maurya, SS; Rawat, DS1
Adeniyi, AA; Awolade, P; Kumar, S; Kumar, V; Legac, J; Rani, A; Rosenthal, PJ; Singh, P1

Reviews

1 review(s) available for 4-aminoquinoline and heme

ArticleYear
4-Aminoquinolines--past, present, and future: a chemical perspective.
    Pharmacology & therapeutics, 1998, Volume: 77, Issue:1

    Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; DNA; Drug Design; Heme; Humans; Models, Molecular; Structure-Activity Relationship

1998

Other Studies

10 other study(ies) available for 4-aminoquinoline and heme

ArticleYear
Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues.
    Journal of medicinal chemistry, 1997, Feb-14, Volume: 40, Issue:4

    Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Heme; Humans; Models, Molecular; Plasmodium falciparum

1997
4-Aminoquinoline derived antimalarials: synthesis, antiplasmodial activity and heme polymerization inhibition studies.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Aminoquinolines; Animals; Antimalarials; Dose-Response Relationship, Drug; Heme; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Polymers; Spectrometry, Mass, Fast Atom Bombardment

2010
2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.
    European journal of medicinal chemistry, 2012, Volume: 52

    Topics: Aminoquinolines; Animals; Antimalarials; Cell Line; DNA; Dogs; Heme; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Plasmodium falciparum; Protoporphyrins; Pyrimidines; Structure-Activity Relationship; Viruses

2012
Novel cinnamic acid/4-aminoquinoline conjugates bearing non-proteinogenic amino acids: towards the development of potential dual action antimalarials.
    European journal of medicinal chemistry, 2012, Volume: 54

    Topics: Amino Acids; Aminoquinolines; Antimalarials; Cinnamates; Cysteine Endopeptidases; Drug Design; Heme; Inhibitory Concentration 50; Molecular Docking Simulation; Molecular Dynamics Simulation; Plasmodium falciparum; Polymerization; Protease Inhibitors; Protein Conformation

2012
4-Aminoquinoline-pyrimidine hybrids: synthesis, antimalarial activity, heme binding and docking studies.
    European journal of medicinal chemistry, 2015, Jan-07, Volume: 89

    Topics: Aminoquinolines; Animals; Antimalarials; Binding Sites; Cell Line; Heme; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimidines

2015
Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi.
    International journal for parasitology. Drugs and drug resistance, 2016, Volume: 6, Issue:3

    Topics: Aminoquinolines; Cell Survival; Heme; Inhibitory Concentration 50; Microscopy, Electron, Transmission; Mitochondria; Trypanocidal Agents; Trypanosoma cruzi

2016
Design, synthesis and evaluation of 4-aminoquinoline-purine hybrids as potential antiplasmodial agents.
    European journal of medicinal chemistry, 2017, Jan-27, Volume: 126

    Topics: Aminoquinolines; Animals; Antimalarials; Binding Sites; Drug Resistance, Fungal; Heme; Humans; Hypoxanthine Phosphoribosyltransferase; Molecular Docking Simulation; Plasmodium falciparum; Purines

2017
Synthesis, antimalarial activity, heme binding and docking studies of N-substituted 4-aminoquinoline-pyrimidine molecular hybrids.
    European journal of medicinal chemistry, 2017, Mar-31, Volume: 129

    Topics: Aminoquinolines; Animals; Antimalarials; Binding Sites; Cell Line; Heme; Humans; Molecular Docking Simulation; Multienzyme Complexes; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase

2017
N-Substituted aminoquinoline-pyrimidine hybrids: Synthesis, in vitro antimalarial activity evaluation and docking studies.
    European journal of medicinal chemistry, 2019, Jan-15, Volume: 162

    Topics: Aminoquinolines; Animals; Antimalarials; Chlorocebus aethiops; Heme; Molecular Docking Simulation; Plasmodium falciparum; Pyrimidines; Vero Cells

2019
Design, synthesis, heme binding and density functional theory studies of isoindoline-dione-4-aminoquinolines as potential antiplasmodials.
    Future medicinal chemistry, 2020, Volume: 12, Issue:3

    Topics: Aminoquinolines; Antimalarials; Binding Sites; Density Functional Theory; Drug Design; Heme; Humans; Isoindoles; Malaria; Microwaves; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum

2020