Page last updated: 2024-08-25

4-aminopyrimidine and indazoles

4-aminopyrimidine has been researched along with indazoles in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Boehm, HJ; Boehringer, M; Bur, D; Gmuender, H; Huber, W; Klaus, W; Kostrewa, D; Kuehne, H; Luebbers, T; Meunier-Keller, N; Mueller, F	1
Aoki, Y; Fukami, TA; Hasegawa, K; Kim, SJ; Miura, T; Na, YJ; Ono, N; Shimma, N; Shindo, H; Shiratori, Y; Suda, A; Tsukuda, T; Yoon, DO	1

Other Studies

2 other study(ies) available for 4-aminopyrimidine and indazoles

Article	Year
Novel inhibitors of DNA gyrase: 3D structure based biased needle screening, hit validation by biophysical methods, and 3D guided optimization. A promising alternative to random screening. Journal of medicinal chemistry, 2000, Jul-13, Volume: 43, Issue:14 Topics: Anti-Infective Agents; Coumarins; Crystallography, X-Ray; DNA Topoisomerases, Type II; Enzyme Inhibitors; Indazoles; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Novobiocin; Protein Binding; Structure-Activity Relationship; Surface Plasmon Resonance; Topoisomerase II Inhibitors; Ultracentrifugation	2000
Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design. Bioorganic & medicinal chemistry letters, 2011, Oct-01, Volume: 21, Issue:19 Topics: Adenosine Triphosphatases; Administration, Oral; Animals; Antineoplastic Agents; Benzopyrans; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Drug Discovery; Escherichia coli; HSP90 Heat-Shock Proteins; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Neoplasms; Reproducibility of Results; Structure-Activity Relationship; Surface Plasmon Resonance; Triazines; Xenograft Model Antitumor Assays	2011

Article

Year

Novel inhibitors of DNA gyrase: 3D structure based biased needle screening, hit validation by biophysical methods, and 3D guided optimization. A promising alternative to random screening.

Journal of medicinal chemistry, 2000, Jul-13, Volume: 43, Issue:14

Topics: Anti-Infective Agents; Coumarins; Crystallography, X-Ray; DNA Topoisomerases, Type II; Enzyme Inhibitors; Indazoles; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Novobiocin; Protein Binding; Structure-Activity Relationship; Surface Plasmon Resonance; Topoisomerase II Inhibitors; Ultracentrifugation

2000

Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design.

Bioorganic & medicinal chemistry letters, 2011, Oct-01, Volume: 21, Issue:19

Topics: Adenosine Triphosphatases; Administration, Oral; Animals; Antineoplastic Agents; Benzopyrans; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Drug Discovery; Escherichia coli; HSP90 Heat-Shock Proteins; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Neoplasms; Reproducibility of Results; Structure-Activity Relationship; Surface Plasmon Resonance; Triazines; Xenograft Model Antitumor Assays

2011