4-aminopyrimidine has been researched along with 2-aminopyrimidine in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boehm, HJ; Boehringer, M; Bur, D; Gmuender, H; Huber, W; Klaus, W; Kostrewa, D; Kuehne, H; Luebbers, T; Meunier-Keller, N; Mueller, F | 1 |
| Aoki, Y; Fukami, TA; Hasegawa, K; Kim, SJ; Miura, T; Na, YJ; Ono, N; Shimma, N; Shindo, H; Shiratori, Y; Suda, A; Tsukuda, T; Yoon, DO | 1 |
| GRAUL, EH; PATZSCHKE, K | 1 |
| Liang, L; Lü, P; Niu, Y; Wang, C; Wang, J; Xu, F; Xu, P; Xu, X | 1 |
| Bhandare, RR; Bloukh, SH; Edis, Z; Jadhav, M; Khan, TA; Sankhe, K | 1 |
1 review(s) available for 4-aminopyrimidine and 2-aminopyrimidine
| Article | Year |
|---|---|
Synthetic Strategies of Pyrimidine-Based Scaffolds as Aurora Kinase and Polo-like Kinase Inhibitors.
Topics: Animals; Antineoplastic Agents; Aurora Kinases; Cell Cycle; Cell Cycle Proteins; Drug Discovery; Humans; Neoplasms; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pyrimidines | 2021 |
4 other study(ies) available for 4-aminopyrimidine and 2-aminopyrimidine
| Article | Year |
|---|---|
Novel inhibitors of DNA gyrase: 3D structure based biased needle screening, hit validation by biophysical methods, and 3D guided optimization. A promising alternative to random screening.
Topics: Anti-Infective Agents; Coumarins; Crystallography, X-Ray; DNA Topoisomerases, Type II; Enzyme Inhibitors; Indazoles; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Novobiocin; Protein Binding; Structure-Activity Relationship; Surface Plasmon Resonance; Topoisomerase II Inhibitors; Ultracentrifugation | 2000 |
Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design.
Topics: Adenosine Triphosphatases; Administration, Oral; Animals; Antineoplastic Agents; Benzopyrans; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Drug Discovery; Escherichia coli; HSP90 Heat-Shock Proteins; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Neoplasms; Reproducibility of Results; Structure-Activity Relationship; Surface Plasmon Resonance; Triazines; Xenograft Model Antitumor Assays | 2011 |
[The effect of 2-hydroxy-4-aminopyrimidine (cytosine) on antibody formation in rabbit].
Topics: Animals; Antibodies; Antibody Formation; Antigens; Cytosine; Pyrimidines; Rabbits | 1953 |
Design, synthesis, and biological evaluation of 4-aminopyrimidine or 4,6-diaminopyrimidine derivatives as beta amyloid cleaving enzyme-1 inhibitors.
Topics: Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Binding Sites; Blood-Brain Barrier; Drug Design; Humans; Molecular Docking Simulation; Permeability; Protease Inhibitors; Protein Structure, Tertiary; Pyrimidines; Structure-Activity Relationship | 2019 |