4-aminopyridine has been researched along with tetrodotoxin in 357 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (23.25) | 18.7374 |
| 1990's | 153 (42.86) | 18.2507 |
| 2000's | 93 (26.05) | 29.6817 |
| 2010's | 26 (7.28) | 24.3611 |
| 2020's | 2 (0.56) | 2.80 |
| Authors | Studies |
|---|---|
| Kaneda, M; Kaneko, A; Ueda, Y | 1 |
| Alonso, A; Llinás, RR | 1 |
| Purali, N; Rydqvist, B | 2 |
| Hofmann, HD; Huba, R; Schneider, H | 1 |
| Sontheimer, H; Waxman, SG | 1 |
| Black, JA; Ransom, BR; Sontheimer, H; Waxman, SG | 1 |
| Coles, JA; Eilbeck, JC; Scott, AC; Vallet, AM | 1 |
| Fredholm, BB; Hu, PS | 1 |
| Golowasch, J; Marder, E | 1 |
| Hatt, H; Hildebrand, JG; Stengl, M; Zufall, F | 1 |
| Black, JA; Kocsis, JD; Utzschneider, D | 1 |
| Andreasen, M; Hablitz, JJ | 1 |
| Cowan, AI; Martin, RL | 1 |
| Carlen, PL; Spigelman, I; Zhang, L | 1 |
| Tack, JF; Wood, JD | 1 |
| Cooke, IM; Graf, RA; Meyers, DE | 1 |
| Strahlendorf, HK; Strahlendorf, JC; Wang, Y | 2 |
| Davidson, N; Hoger, JH; Lester, HA; Rudy, B | 1 |
| de Waele, C; Khateb, A; Mühlethaler, M; Serafin, M; Vidal, PP | 1 |
| Bao, JX; Msghina, M; Stjärne, E; Stjärne, L | 1 |
| Coulter, DA; Huguenard, JR; Prince, DA | 1 |
| Amédée, T; Dupouy, B; Ellie, E; Vincent, JD | 1 |
| Dye, J | 1 |
| Dourado, MM; Dryer, SE; Wisgirda, ME | 1 |
| Furukawa, T; Katsuragi, T; Ogawa, S; Shirakabe, K; Soejima, O | 1 |
| Blasquez, C; Bunel, DT; Delbende, C; Jégou, S; Vaudry, H | 1 |
| Mawe, GM | 1 |
| Aitken, PG; Jing, J; Somjen, GG; Young, J | 1 |
| Estacion, M | 1 |
| Saito, M; Wu, CF | 1 |
| Allgaier, C; Hertting, G; Huang, HY; Jackisch, R | 1 |
| Kiraly, M; Liao, GS; Maillard, M | 1 |
| Leung, LW; Yim, CY | 1 |
| Graubard, K; Hartline, DK | 1 |
| McCormick, DA | 1 |
| Bagetta, G; Constanti, A | 1 |
| Baxter, DA; Byrne, JH; Critz, SD | 1 |
| Akaike, N; Harata, N; Oyama, Y | 1 |
| Nasi, E | 1 |
| Dolezal, V; Wecker, L | 1 |
| Augustine, GJ | 1 |
| Hirose, T; Inagaki, C; Inoue, M | 1 |
| Fedida, D; Kilborn, MJ | 1 |
| Greene, RW; Haas, HL; Reiner, PB | 1 |
| Dankó, M; Lathrop, DA; Nánási, PP | 1 |
| Beam, KG; Best, PM; McCobb, DP | 1 |
| Bernath, S; Zigmond, MJ | 1 |
| Hsiung, GR; Puil, E | 1 |
| Buyukuysal, RL; Wurtman, RJ | 1 |
| Avoli, M; Palma, E; Pirrone, GC; Tancredi, V; Zona, C | 1 |
| Eng, DL; Gordon, TR; Kocsis, JD; Waxman, SG | 1 |
| Mitsoglou, GM; Padjen, AL | 1 |
| Yang, J; Zorumski, CF | 1 |
| Grace, AA | 1 |
| Duval, A; Léoty, C | 1 |
| Hartung, K | 1 |
| Kojima, H; Kuno, M; Yawo, H | 1 |
| Giles, WR; van Ginneken, AC | 1 |
| Angaut-Petit, D; Mallart, A | 1 |
| Bevan, S; Chiu, SY; Gray, PT; Ritchie, JM | 1 |
| Dreyer, F; Penner, R; Petersen, M; Pierau, FK | 1 |
| Cooke, IM; Tazaki, K | 1 |
| Ascher, P; Berwald-Netter, Y; Nowak, L | 1 |
| Ohba, M | 1 |
| Connor, JA; Hockberger, PE; Tseng, HY | 1 |
| Segal, M | 1 |
| Baker, M; Bostock, H; Grafe, P; Martius, P | 1 |
| Chiu, SY | 1 |
| Brown, AM; Marchetti, C; Premont, RT | 1 |
| Hounsgaard, J; Mintz, I | 1 |
| Alvarez de Toledo, G; López-Barneo, J | 1 |
| Hirsch, JA; Oertel, D | 1 |
| Palmer, JM; Tamura, K; Winkelmann, CK; Wood, JD | 1 |
| Kehl, SJ | 1 |
| Cynader, MS; Shaw, C; van Huizen, F; Wilkinson, M | 1 |
| Alkon, DL; Coulter, DA; Disterhoft, JF; Kubota, M; Lo Turco, JJ; Moore, JW | 1 |
| Magistretti, PJ; Martin, JL | 1 |
| Puil, E; Spigelman, I | 1 |
| Hiraoka, M; Kawano, S | 1 |
| Boldt, W; Schüttler, K | 1 |
| Gispen, WH; Heemskerk, FM; Schrama, LH | 1 |
| Aldrete, V; Drury, T; Giles, W; Refsum, H; Shibata, EF | 1 |
| Cheng, JT; Hsu, SY; Shen, CL | 1 |
| Gündel, J; Matthies, H; Tennigkeit, M; Wicher, C | 1 |
| Avoli, M; Perreault, P | 1 |
| Molgó, J; Pécot-Dechavassine, M; Thesleff, S | 1 |
| Llinás, RR; MacVicar, BA | 1 |
| Chinn, KS; Gillary, HL | 1 |
| Hirst, GD; Johnson, SM; van Helden, DF | 1 |
| Chaudhry, IA; Duncalf, D; Foldes, FF; Goldiner, PL; Nagashima, H; Somogyi, GT; Vizi, ES | 1 |
| Lew, MJ; White, TD | 1 |
| Biessels, PT; Damsma, G; De Vries, JB; Horn, AS; Westerink, BH | 1 |
| Konnerth, A; Orkand, PM; Orkand, RK | 1 |
| Krieger, C; Sears, TA | 1 |
| Chiba, S; Furukawa, Y; Saegusa, K | 1 |
| Morales, E; Sitges, M; Tapia, R | 1 |
| Atwood, HL; Parnas, H; Parnas, I; Wojtowicz, JM | 1 |
| Lang, B; Newsom-Davis, J; Wray, DW | 1 |
| Quastel, DM; Saint, DA | 1 |
| Ceña, V; García, AG; Gonzalez-Garcia, C; Kirpekar, SM | 1 |
| Guerrero, S; Zacharias, J | 1 |
| Gonzalez, DR; Morales-Aguilera, A | 1 |
| Boev, K; Bonev, A; Papasova, M | 1 |
| Kato, H; Takata, Y | 1 |
| Muller, D | 1 |
| Llinás, R; Yarom, Y | 1 |
| Sonoki, H; Sugimoto, T; Tomaru, T; Uchida, Y | 1 |
| Haydon, DA; Requena, J; Simon, AJ | 1 |
| Scholfield, CN | 1 |
| Hotta, K; Oba, T | 1 |
| Atwood, HL; Wojtowicz, JM | 1 |
| Guerrero, S; Lemeignan, M; Molgó, J | 1 |
| Anderson, PA; Schwab, WE | 1 |
| Gold, MR; Martin, AR | 1 |
| Patterson, BA; Volle, RL | 1 |
| Sowoidnich, T; Zetler, G | 1 |
| Ahnert-Hilger, G; Habermann, E | 1 |
| Mulder, AH; Schoffelmeer, AN; Wemer, J | 1 |
| Lymangrover, JR; Matthews, EK; Saffran, M | 1 |
| Buckle, PJ; Haas, HL | 1 |
| Molgó, J; Thesleff, S | 1 |
| Kecskeméti, V; Kelemen, K; Knoll, J; Marko, R | 1 |
| Edman, A; Gestrelius, S; Grampp, W | 1 |
| Mallart, A | 1 |
| Barker, JL; Segal, M | 1 |
| Douglas, WW; Taraskevich, PS; Tomiko, SA | 1 |
| Barker, JL; Rogawski, MA | 1 |
| Downing, OA; Louttit, JB; Wilson, KA | 1 |
| Illes, P; Meier, C; Starke, K | 1 |
| Miledi, R; Parker, I; Zhu, PH | 1 |
| Imaizumi, Y; Watanabe, M | 1 |
| Dolezal, V; Tucek, S | 1 |
| Anraku, M; Hashimura, S | 1 |
| Gallin, EK; Livengood, DR | 1 |
| Fujiwara, M; Ikushima, S; Muramatsu, I | 1 |
| Aceves, J; Cuello, AC | 1 |
| Terakawa, S | 1 |
| Safronov, BV; Vogel, W | 1 |
| Chang, JP; Goldberg, JI; Price, CJ | 1 |
| Bonev, AD; Mawe, GM; Nelson, MT; Zhang, L | 1 |
| Banks, MI; Pearce, RA; Smith, PH | 1 |
| Brouard, A; Lhiaubet, AM; Pelaprat, D; Rostène, W; Vial, M | 1 |
| Boeckxstaens, GE; De Man, JG; Herman, AG; Pelckmans, PA | 1 |
| Bittner, GD; Fishman, HM; Krause, TL | 1 |
| Chen, W; Hui, CS | 1 |
| Boom, HB; Wallinga, W; Wolters, H; Ypey, DL | 1 |
| French, AS; Torkkeli, PH | 1 |
| Horie, M; James, AF; Okada, T | 1 |
| Andreasen, M; Lambert, JD | 1 |
| Huang, HY; Zhou, CW | 1 |
| Fu, WM; Lin-Shiau, SY; Liu, SH | 1 |
| Boos, R; Schneider, H; Wässle, H | 1 |
| Dunlap, K; Turner, TJ | 1 |
| Kapetanovic, IM; Kupferberg, HJ; Yonekawa, WD | 3 |
| Nisenbaum, ES; Wilson, CJ | 1 |
| Huang, HY; Huang, YZ; Xie, PG | 1 |
| Carmeliet, E; Flameng, W; Mubagwa, K | 1 |
| Katina, IE; Lukyanenko, V; Nasledov, GA | 1 |
| Avoli, M; Mattia, D; Perreault, P; Siniscalchi, A; Tomaiuolo, F | 1 |
| Ekmehag, B; Persson, B; Rorsman, H; Rorsman, P | 1 |
| Donnelly, DF; Doyle, TP | 1 |
| Basavappa, S; Brammer, M; Campbell, I; Laro, D; Mangel, AW; Romano-Silva, MA | 1 |
| Cahill, AL; Perlman, RL | 1 |
| Logue, AR; Maciag, CM; Saydoff, JA; Tam, SW; Tinker, WJ; Zaczek, R | 1 |
| Allgaier, C; Schobert, A; Starke, K; von Kügelgen, I | 1 |
| Clark, BA; Mobbs, P | 1 |
| Miyamoto, MD; Provan, SD | 1 |
| Golard, A; Siegelbaum, SA | 1 |
| Osmanović, SS; Pan, WJ; Shefner, SA | 1 |
| Bouchard, RA; Clark, RB; Giles, WR | 1 |
| Nisenbaum, ES; Wilson, CJ; Xu, ZC | 1 |
| Fleischmann, BK; Kotlikoff, MI; Washabau, RJ | 1 |
| Fisher, ND; Nistri, A | 1 |
| Avoli, M; Brancati, A; Calissano, P; Ciotti, MT; Mercanti, D; Ragozzino, D; Zona, C | 1 |
| Paudice, P; Raiteri, M; Vallebuona, F | 1 |
| Clemens, A; Creutzfeldt, W; Katsoulis, S; Köhler, H; Schmidt, WE; Schwörer, H | 1 |
| Hoehn, K; MacVicar, BA; Watson, TW | 1 |
| Bardoni, R; Belluzzi, O | 1 |
| Grace, AA; O'Donnell, P | 1 |
| Foster, WR; Paton, JF; Schwaber, JS | 1 |
| Chandler, SH; Hsiao, CF | 1 |
| Hisashi, K; Kimitsuki, T; Komiyama, S; Komune, S; Nakagawa, T; Yasuda, T | 1 |
| Dolly, JO; Nicholls, DG; Tibbs, GR | 1 |
| Konishi, T | 1 |
| Bardoni, R; Belluzzi, O; Magherini, PC; Puopolo, M | 1 |
| Oka, Y | 1 |
| Bauer, RM; Benton, BJ; Capacio, BR; Chang, FC; Keller, SA | 1 |
| Hay, M; Lindsley, KA | 1 |
| Deisz, RA | 1 |
| Ağar, E; Green, GG; Sanders, DJ | 2 |
| Funabiki, K; Koyano, K; Ohmori, H | 1 |
| Klis, SF; Smoorenburg, GF; van Emst, MG | 1 |
| Mendelowitz, D; Mihalevich, M; Neff, RA | 1 |
| Antzelevitch, C; Goodrow, RJ; Zygmunt, AC | 1 |
| García-Segoviano, JA; Naranjo-Rodríguez, EB; Prieto-Gómez, B; Reyes-Vázquez, C; Trujillo-Santana, JT | 1 |
| Jánossy, A; Jurányi, Z; Orsó, E; Sperlágh, B; Szalay, KS; Vinson, GP; Vizi, ES; Windisch, K | 1 |
| Armstrong, WE; Stern, JE | 1 |
| Kapoor, R; Li, YG; Smith, KJ | 1 |
| Hirono, M; Kawahara, K; Suzuki, N; Yoshioka, T | 1 |
| Benton, BJ; Capacio, BR; Chang, FC; Keller, SA; Spriggs, DL | 1 |
| Cousin, MA; Hurst, H; Nicholls, DG | 1 |
| Emaduddin, M; Kurono, M; Takeuchi, H; Zhang, W | 1 |
| Binding, N; Madeja, M; Musshoff, U; Speckmann, EJ; Witting, U | 1 |
| Driesang, RB; Pape, HC | 1 |
| Puil, E; Schwarz, DW | 1 |
| Puil, E; Schwarz, DW; Tennigkeit, F | 1 |
| Bencsics, A; Nakai, T; Sato, T; Uchihashi, Y; Umeda, E; Vizi, ES | 1 |
| Myers, AC | 1 |
| Avoli, M; Kawasaki, H; Methot, M | 1 |
| Fieber, LA | 1 |
| Strata, F | 1 |
| Etzion, Y; Grossman, Y | 2 |
| Alexandre, A; Cavallini, L; Zoccarato, F | 1 |
| Ayala, GX; Bargas, J; Galarraga, E; Pineda, JC; Vilchis, C | 1 |
| Puil, E; Ries, CR | 1 |
| Albuquerque, EX; Braga, MF; Pereira, EF | 1 |
| de Groat, WC; Yoshimura, N | 1 |
| Bernardi, G; Bonci, A; Grillner, P; Mercuri, NB; Svensson, TH | 1 |
| Brotchie, JM; Hill, MP | 1 |
| Strowbridge, BW | 1 |
| Wang, JK | 1 |
| Fedulova, SA | 1 |
| Batini, C; Vigot, R | 1 |
| Martina, M; Paré, D; Royer, S | 1 |
| Carruth, M; Magee, JC | 1 |
| Laurier, LG; Preiksaitis, HG; Sims, SM; Wade, GR | 1 |
| Baraban, SC; Bikson, M; Durand, DM; Ghai, RS | 1 |
| Easaw, JC; Harris, KH; Jassar, BS; Jhamandas, JH | 1 |
| Delgado-García, JM; Magariños-Ascone, C; Núñez, A | 1 |
| Smith, GT; Zakon, HH | 1 |
| Kuprijanova, E; Seifert, G; Steinhäuser, C; Zhou, M | 1 |
| Di Pasquale, E; Hilaire, G; Konrad, M; Monteau, R; Ptak, K; Tell, F | 1 |
| Obrenovitch, TP | 1 |
| French, AS; Sekizawa, SI; Torkkeli, PH | 1 |
| Ahnert-Hilger, G; Draguhn, A; Grosse, G; Höhne, L; Tapp, R; Veh, RW | 1 |
| Jones, MB; Odblom, MP; Williamson, R | 1 |
| Hillsley, K; Smith, TK; Vogalis, F | 1 |
| Blandizzi, C; Colucci, R; Del Tacca, M; Tognetti, M | 1 |
| Bekkers, JM | 1 |
| Korngreen, A; Sakmann, B | 1 |
| Djamgoz, MB; Fraser, SP; Grimes, JA | 1 |
| Gotoh, M; Kawai, N; Konno, K; Miwa, A; Robinson, HP; Sahara, Y; Tsubokawa, H | 1 |
| Lucero, MT; Mujtaba, T; Piper, DR; Rao, MS | 1 |
| Araki, I; de Groat, WC; Kawatani, M; Miura, A | 1 |
| Bal, R; Oertel, D | 1 |
| Kelly, MJ; Reyes-Vazquez, C; Ronnekleiv, OK; Wagner, EJ | 1 |
| Adelsberger, H; Eckel, F; Grosskreutz, J; Lepier, A; Lersch, C; Quasthoff, S | 1 |
| Gritti, A; Lecchi, M; Rosati, B; Vescovi, AL; Wanke, E | 1 |
| Hu, HJ; Pan, ZH | 1 |
| Häusser, M; Stuart, GJ | 1 |
| Alger, BE; Morishita, W | 1 |
| Armano, S; D'Angelo, E; Fontana, A; Maffei, A; Naldi, G; Nieus, T; Rossi, P; Taglietti, V | 1 |
| Irnaten, M; Mendelowitz, D; Wang, J | 1 |
| Oliver, DL; Sivaramakrishnan, S | 1 |
| El Manira, A; Hess, D | 1 |
| Chung, JM; Chung, K; Liu, X; Zhou, JL | 1 |
| Kuba, K; Lu, FM | 1 |
| Chandler, SH; Hsiao, CF; Wu, N | 1 |
| Ashida, Y; Denda, M; Inoue, K; Kumazawa, N | 1 |
| DeFazio, RA; Geusz, ME; Herzog, ED; Moenter, SM; Nunemaker, CS; Pitts, GR | 1 |
| Adam, TJ; Finlayson, PG; Schwarz, DW | 1 |
| Häusser, M; Roth, A | 1 |
| Du, J; Feng, L; Johnson, SW; Lu, B; Shen, L; Wu, CP; Yang, F; Zheng, F | 1 |
| Barrionuevo, G; González-Burgos, G | 1 |
| Beekenkamp, H; Bossu, JL; Cavelier, P; Desplantez, T; Pouille, F | 1 |
| Agrawal, SK; Chung, I; Fehlings, MG; Nashmi, R; Velumian, AA; Zhang, L | 1 |
| Adams, DJ; Hogg, RC; Lewis, RJ | 1 |
| Persaud, N; Strichartz, GR | 1 |
| Alger, B; Brager, D; Lenz, RA; London, B; Morishita, W; Varma, N | 1 |
| Cornfield, DN; Hong, Z; Linden, BC; Olschewski, A; Porter, VA; Weir, EK | 1 |
| Birthelmer, A; Cassel, JC; Jackisch, R; Jeltsch, H; Schweizer, T | 1 |
| Bourque, CW; Buss, RR; Drapeau, P | 1 |
| Frick, A; Johnston, D; Koester, HJ; Magee, J; Migliore, M | 1 |
| Christie, JM; Westbrook, GL | 1 |
| Abarca, C; Gutiérrez, Mdel C; Possani, LD | 1 |
| Boerrigter, P; Gorji, A; Klitgaard, H; Madeja, M; Margineanu, DG; Siep, E; Speckmann, EJ | 1 |
| Namba, H; Nawa, H; Takei, N | 1 |
| Albrecht, D; Klueva, J; Munsch, T; Pape, HC | 1 |
| Galván, E; Sitges, M | 1 |
| Basille, M; Castel, H; Fournier, A; Gonzalez, BJ; Mei, YA; Vaudry, D; Vaudry, H | 1 |
| Blanks, AM; Lee, K; Spanswick, D; van den Top, M; Whyment, AD | 1 |
| Feuerstein, TJ; Freiman, TM; Surges, R | 1 |
| Chang, IY; Choi, S; Jun, JY; Kim, KW; Kim, MJ; Kim, MY; Kong, ID; Lee, KP; Park, CK; So, I; Yeum, CH; You, HJ | 1 |
| Balu, R; Larimer, P; Strowbridge, BW | 1 |
| Liu, X; Stan Leung, L | 1 |
| Barrionuevo, G; Grace, AA; Kröner, S; Rosenkranz, JA | 1 |
| Ceña, V; Fariñas, I; González-García, C; Martín, ED; Milán, M | 1 |
| Akaike, T; Murai, Y | 1 |
| Araque, A; Perea, G | 1 |
| Deng, X; Lau, CP; Li, GR; Sun, H | 1 |
| Campanucci, VA; Nurse, CA | 1 |
| Galván, E; Nekrassov, V; Sitges, M | 1 |
| Tang, SL; Tran, V; Wagner, EJ | 1 |
| Gruhn, M; Guckenheimer, J; Harris-Warrick, RM; Land, B | 1 |
| Albertí, E; Jiménez, M | 1 |
| Limón, A; Pérez, C; Soto, E; Vega, R | 1 |
| Liao, L; Liu, LY; Lu, BX; Mei, YA; Zhang, ZH | 1 |
| Fukuda, S; Hisatsune, T; Namba, T; Seki, T; Tozuka, Y | 1 |
| Kang, J; Kang, N; Nedergaard, M; Xu, J; Xu, Q | 1 |
| Hemmings, HC; Westphalen, RI | 1 |
| Liao, C; Nicholson, RA | 1 |
| Belugin, S; Mifflin, S | 1 |
| Laursen, M; Rekling, JC | 1 |
| Bae, YC; Hirai, T; Kang, Y; Maeda, Y; Saito, M; Sato, H; Toyoda, H | 1 |
| Inoue, H; Okada, Y | 1 |
| Bargas, J; Galarraga, E; Hernandez-Echeagaray, E; Perez-Garci, E; Perez-Rosello, T; Salgado, H; Surmeier, DJ; Tecuapetla, F; Tkatch, T; Vilchis, C | 1 |
| Fu, H; Hu, B; Liu, H; Liu, L; Xiang, J | 1 |
| Kadoi, J; Kitagawa, J; Matsumoto, S; Saiki, C; Takahashi, M; Takeda, M; Yoshida, S | 1 |
| Hammack, SE; Mania, I; Rainnie, DG | 1 |
| Kito, Y; Suzuki, H | 1 |
| Arimura, Y; Eto, K; Ishibashi, H; Nabekura, J; Noda, M | 1 |
| de Groat, WC; Sculptoreanu, A; Yamane, H | 1 |
| Cho, CH; Li, GR; Wang, JY; Wong, TM; Wu, WK; Yu, L | 1 |
| Hurwitz, I; Koester, J; Korngreen, A; Ophir, A; Susswein, AJ | 1 |
| Budelli, R; Curti, S; Gómez, L; Pereda, AE | 1 |
| Behzadi, G; Haghdoost-Yazdi, H; Janahmadi, M | 1 |
| Chapman, CA; Glasgow, SD | 1 |
| Acker, CD; Antic, SD | 1 |
| Bal, R; Baydas, G | 1 |
| Chen, H; Jiang, L; Leng, J; Zhang, X | 1 |
| Han, VZ; Hu, SJ; Kuang, F; Liu, YH; Wu, NP; Xing, JL; Yang, J; Zhang, CZ | 1 |
| Belardinelli, L; January, CT; Li, H; Rajamani, S; Shryock, JC; Wu, L | 1 |
| Adesnik, H; Hull, C; Scanziani, M | 1 |
| Li, GQ; Meredith, FL; Rennie, KJ | 1 |
| Engel, D; Seutin, V | 1 |
| Hemmings, HC; Jih, TY; Krivitski, M; Westphalen, RI; Yu, J | 1 |
| Haufler, D; Lacaille, JC; Morin, F; Skinner, FK | 1 |
| Aldana, BI; Chiu, LM; Guarneros, A; Sanchez-Tafolla, BM; Sitges, M | 1 |
| Chavis, P; Farrugia, F; Garenne, A; Le Masson, G; Manzoni, OJ; Marsicano, G; Piet, R | 1 |
| Ikegaya, Y; Matsuki, N; Sasaki, T | 1 |
| Coquinco, A; Craig, AM; Cynader, M; Kaufman, AM; Lee, H; Milnerwood, AJ; Raymond, LA; Sepers, MD; She, K; Wang, L | 1 |
| Daftary, S; Ehrlich, DE; Jasnow, AM; Madsen, TE; Rainnie, DG; Ryan, SJ | 1 |
| Nair, SS; Ransdell, JL; Schulz, DJ | 1 |
| Anderova, M; Honsa, P; Pivonkova, H | 1 |
| Cao, PX; Han, LM; Li, BY; Li, JN; Liu, DJ; Liu, Y; Lu, XL; Pan, XD; Qian, Z; Qiao, GF; Wang, HY; Wang, LJ; Xu, B; Yuan, M | 1 |
| Davis, RL; Lee, E; Liu, Q | 1 |
| Maccaferri, G; Quattrocolo, G | 1 |
| Hu, S; Li, F; Xing, J; Yang, J | 1 |
| Granger, AJ; Sabatini, BL; Saunders, A | 1 |
| Li, SS; Liu, CW; Sun, FY; Wu, KW; Yang, P | 1 |
| Chang, CY; Chou, SS; Huang, SK; Lin, TY; Lu, CW; Wang, SJ; Wang, YC | 1 |
| Fontanini, A; Haley, MS; Maffei, A | 1 |
| Chen, Z; Travers, JB; Travers, SP | 1 |
| Al Awabdh, S; Griffin, LD; Gupta-Agarwal, S; Kittler, JT; Muir, J; Norkett, R; Sheehan, DF; Twelvetrees, AE | 1 |
| Baird-Daniel, E; Daniel, AGS; Laffont, P; Li, D; Liou, JY; Ma, H; Schwartz, TH; Wenzel, M; Yuste, R; Zhao, M | 1 |
| Muthuchamy, M; Reddy, DS; Wu, X | 1 |
| Campeiro, JD; Duarte, T; Godinho, RO; Hayashi, MAF; Lima, ÁDC; Lima, SC; Meurer, Y; Oliveira, EB; Picolo, G; Porta, LC; Silva, RH; Teixeira, NB | 1 |
| Franke, H; Illes, P; Khan, MT; Liu, J; Nerlich, J; Tang, Y | 1 |
| Derbenev, AV; Gao, H; Heesch, CM; Korim, WS; Yao, ST | 1 |
| Ayata, C; Chung, DY; de Morais, AL; Endres, M; Loonen, ICM; Misra, A; Qin, T; Schiff, SJ; Schlunk, F; Tamim, I | 1 |
| Chakraborty, P; Holmuhamedov, EL; Jahangir, A; Liu, X; Oberlin, A; Shen, WK; Terzic, A; Yousufuddin, M | 1 |
1 review(s) available for 4-aminopyridine and tetrodotoxin
| Article | Year |
|---|---|
High extracellular glutamate and neuronal death in neurological disorders. Cause, contribution or consequence?
Topics: 4-Aminopyridine; Animals; Calcium; Cell Death; Cortical Spreading Depression; Excitatory Amino Acid Antagonists; Exocytosis; Glutamic Acid; Glutamine; Nervous System Diseases; Neurons; Potassium; Potassium Channel Blockers; Presynaptic Terminals; Rats; Sodium Channel Blockers; Tetrodotoxin | 1999 |
356 other study(ies) available for 4-aminopyridine and tetrodotoxin
| Article | Year |
|---|---|
Voltage-dependent ionic currents in solitary horizontal cells isolated from cat retina.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Action Potentials; Animals; Calcium Channels; Cats; Cells, Cultured; Cesium; Electric Conductivity; Membrane Potentials; Nifedipine; Potassium Channels; Retinal Ganglion Cells; Sodium; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1992 |
Electrophysiology of the mammillary complex in vitro. I. Tuberomammillary and lateral mammillary neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cadmium; Calcium; Electrophysiology; Guinea Pigs; In Vitro Techniques; Ion Channels; Mammillary Bodies; Neurons; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1992 |
Block of potassium outward currents in the crayfish stretch receptor neurons by 4-aminopyridine, tetraethylammonium chloride and some other chemical substances.
Topics: 4-Aminopyridine; Animals; Apamin; Astacoidea; Carbachol; Charybdotoxin; In Vitro Techniques; Kinetics; Mechanoreceptors; Muscles; Neurons; Potassium Channels; Reflex; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1992 |
Voltage-gated currents of putative GABAergic amacrine cells in primary cultures and in retinal slice preparations.
Topics: 4-Aminopyridine; Animals; Calcium Channels; Cells, Cultured; Chick Embryo; Cobalt; Electric Conductivity; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Neurons; Phenotype; Potassium Channels; Retina; Sodium Channels; Tetraethylammonium Compounds; Tetrodotoxin | 1992 |
Ion channels in spinal cord astrocytes in vitro. II. Biophysical and pharmacological analysis of two Na+ current types.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Kinetics; Membrane Potentials; Rats; Rats, Sprague-Dawley; Sodium Channels; Spinal Cord; Tetrodotoxin | 1992 |
Ion channels in spinal cord astrocytes in vitro. I. Transient expression of high levels of Na+ and K+ channels.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Membrane Potentials; Potassium Channels; Rats; Rats, Sprague-Dawley; Sodium Channels; Spinal Cord; Tetrodotoxin | 1992 |
Membrane conductances involved in amplification of small signals by sodium channels in photoreceptors of drone honey bee.
Topics: 4-Aminopyridine; Action Potentials; Animals; Bees; Light; Mathematics; Membrane Potentials; Models, Biological; Photometry; Photoreceptor Cells; Potassium Channels; Sodium Channels; Tetrodotoxin | 1992 |
4-Aminopyridine-induced increase in basal and stimulation-evoked [3H]-NA release in slices from rat hippocampus: Ca2+ sensitivity and presynaptic control.
Topics: 4-Aminopyridine; Animals; Calcium; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Tritium | 1991 |
Ionic currents of the lateral pyloric neuron of the stomatogastric ganglion of the crab.
Topics: 4-Aminopyridine; Animals; Barium; Brachyura; Calcium Channels; Electrophysiology; Ganglia; Ion Channels; Isoquinolines; Kinetics; Microelectrodes; Neural Conduction; Neurons; Pylorus; Sodium Channels; Tetraethylammonium Compounds; Tetrodotoxin; Virulence Factors, Bordetella | 1992 |
Olfactory receptor neurons from antennae of developing male Manduca sexta respond to components of the species-specific sex pheromone in vitro.
Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Calcium Channel Blockers; Cations; Cells, Cultured; Cyclic GMP; Electric Conductivity; Ion Channels; Membrane Potentials; Moths; Neurons; Pheromones; Potassium Chloride; Sensory Receptor Cells; Tetrodotoxin | 1992 |
Conduction properties of spinal cord axons in the myelin-deficient rat mutant.
Topics: 4-Aminopyridine; Animals; Axons; Electric Stimulation; Evoked Potentials; Female; gamma-Aminobutyric Acid; Male; Membrane Potentials; Microscopy, Electron; Myelin Sheath; Neural Conduction; Rats; Rats, Mutant Strains; Reference Values; Spinal Cord; Tetrodotoxin | 1992 |
Kinetic properties of a transient outward current in rat neocortical neurons.
Topics: 4-Aminopyridine; Animals; Cells, Cultured; Cerebral Cortex; Electric Conductivity; Embryo, Mammalian; Evoked Potentials; Kinetics; Mathematics; Membrane Potentials; Neurons; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1992 |
Ionic basis of membrane potential changes induced by anoxia in rat dorsal vagal motoneurones.
Topics: 4-Aminopyridine; Action Potentials; Animals; Apamin; Hypoxia; Ions; Male; Manganese; Membrane Potentials; Motor Neurons; Oxygen; Rats; Rats, Wistar; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Vagus Nerve | 1992 |
Patch-clamp study of postnatal development of CA1 neurons in rat hippocampal slices: membrane excitability and K+ currents.
Topics: 4-Aminopyridine; Action Potentials; Aging; Animals; Electrophysiology; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Potassium Channels; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds; Tetrodotoxin | 1992 |
Electrical behaviour of myenteric neurones in the gastric antrum of the guinea-pig.
Topics: 4-Aminopyridine; Action Potentials; Animals; Apamin; Colforsin; Electrophysiology; Guinea Pigs; Membrane Potentials; Myenteric Plexus; Neurons; Pyloric Antrum; Tetraethylammonium Compounds; Tetrodotoxin | 1992 |
Ionic currents of morphologically distinct peptidergic neurons in defined culture.
Topics: 4-Aminopyridine; Animals; Calcium; Cells, Cultured; Electrophysiology; Male; Neurons; Neuropeptides; Potassium; Sodium; Strontium; Tetrodotoxin | 1992 |
Serotonin reduces a voltage-dependent transient outward potassium current and enhances excitability of cerebellar Purkinje cells.
Topics: 4-Aminopyridine; Animals; Cerebellum; Cesium; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Nickel; Potassium Channels; Purkinje Cells; Rats; Serotonin; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1992 |
Characterization of maintained voltage-dependent K(+)-channels induced in Xenopus oocytes by rat brain mRNA.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Brain Chemistry; Calcium Channel Blockers; Electrophysiology; Ion Channel Gating; Membrane Potentials; Microinjections; Oocytes; Potassium Channels; Rats; RNA, Messenger; Synaptosomes; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Xenopus laevis | 1991 |
Medial vestibular nucleus in the guinea-pig. II. Ionic basis of the intrinsic membrane properties in brainstem slices.
Topics: 4-Aminopyridine; Action Potentials; Animals; Brain Stem; Cadmium; Calcium Channels; Cell Membrane; Cobalt; Electric Conductivity; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Neurons; Potassium Channels; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Vestibular Nuclei | 1991 |
K+ and Ca2+ channel blockers may enhance or depress sympathetic transmitter release via a Ca(2+)-dependent mechanism "upstream" of the release site.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Guinea Pigs; Ion Channel Gating; Male; Manganese; Mice; Microelectrodes; Models, Neurological; Norepinephrine; Potassium; Potassium Channels; Rats; Rats, Inbred Strains; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
A fast transient potassium current in thalamic relay neurons: kinetics of activation and inactivation.
Topics: 4-Aminopyridine; Animals; Biotransformation; Calcium Channels; Electrophysiology; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons; Potassium Channels; Rats; Rats, Inbred Strains; Temperature; Tetraethylammonium Compounds; Tetrodotoxin; Thalamus | 1991 |
Voltage-dependent calcium and potassium channels in Schwann cells cultured from dorsal root ganglia of the mouse.
Topics: 4-Aminopyridine; Animals; Barium; Calcium Channels; Cells, Cultured; Cobalt; Dose-Response Relationship, Drug; Ganglia, Spinal; Membrane Potentials; Mice; Nifedipine; Potassium Channels; Schwann Cells; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
Ionic and synaptic mechanisms underlying a brainstem oscillator: an in vitro study of the pacemaker nucleus of Apteronotus.
Topics: 4-Aminopyridine; Animals; Biological Clocks; Brain Stem; Calcium; Cold Temperature; Electric Fish; Fourier Analysis; Glutamates; Glutamic Acid; Humans; In Vitro Techniques; Potassium Channels; Sodium Channels; Synapses; Tetrodotoxin | 1991 |
Properties of Ca2+ currents in acutely dissociated neurons of the chick ciliary ganglion: inhibition by somatostatin-14 and somatostatin-28.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Animals; Calcium; Calcium Channels; Cells, Cultured; Chick Embryo; Ganglia, Parasympathetic; GTP-Binding Proteins; Ion Channel Gating; Neurons; Nifedipine; Pertussis Toxin; Potassium; Potassium Channels; Somatostatin; Somatostatin-28; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Virulence Factors, Bordetella | 1991 |
Involvement of dihydropyridine-sensitive Ca2+ channels in adenosine-evoked inhibition of acetylcholine release from guinea pig ileal preparation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Acetylcholine; Adenosine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Calcium Channels; Chromatography, High Pressure Liquid; Dihydropyridines; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle, Smooth; Nifedipine; Physostigmine; Tetrodotoxin; Theophylline | 1990 |
Effects of ions and ionic channel activators or blockers on release of alpha-MSH from perifused rat hypothalamic slices.
Topics: 4-Aminopyridine; alpha-MSH; Animals; Bicuculline; Calcium; Chlorides; Hypothalamus; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Muscimol; Ouabain; Potassium; Rats; Rats, Inbred Strains; Secretory Rate; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Veratridine | 1990 |
Intracellular recording from neurones of the guinea-pig gall-bladder.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Animals; Apamin; Bethanechol; Bethanechol Compounds; Calcium; Curare; Gallbladder; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Neurons; Serotonin; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1990 |
Ion channel involvement in hypoxia-induced spreading depression in hippocampal slices.
Topics: 4-Aminopyridine; Animals; Cortical Spreading Depression; Evoked Potentials; Female; Hippocampus; Hypoxia; In Vitro Techniques; Ion Channels; Rats; Rats, Inbred Strains; Reaction Time; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
Characterization of ion channels seen in subconfluent human dermal fibroblasts.
Topics: 4-Aminopyridine; Calcium; Cells, Cultured; Electric Conductivity; Fibroblasts; Humans; Ion Channel Gating; Ion Channels; Kinetics; Potassium Channels; Skin; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
Expression of ion channels and mutational effects in giant Drosophila neurons differentiated from cell division-arrested embryonic neuroblasts.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channels; Cell Differentiation; Cell Division; Drosophila melanogaster; Electric Conductivity; Ion Channels; Mutation; Neurons; Potassium Channels; Sodium; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
3,4-Diaminopyridine-evoked noradrenaline release in rat hippocampus: role of Na+ entry on Ca2+ pools and of protein kinase C.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Animals; Calcium; Cytosol; Hippocampus; In Vitro Techniques; Male; Neurotransmitter Agents; Norepinephrine; Phorbol 12,13-Dibutyrate; Polymyxin B; Protein Kinase C; Rats; Rats, Inbred Strains; Ruthenium Red; Sodium; Tetrodotoxin | 1991 |
Ion channels involved in the presynaptic hyperexcitability induced by herpes virus suis in rat superior cervical ganglion.
Topics: 4-Aminopyridine; Action Potentials; Animals; Atropine; Calcium Channel Blockers; Electric Stimulation; Evoked Potentials; Ganglia, Sympathetic; Herpesvirus 1, Suid; Hexamethonium; Hexamethonium Compounds; Ion Channels; Male; Neurons; Physostigmine; Pirenzepine; Pseudorabies; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin | 1991 |
Intrinsic membrane potential oscillations in hippocampal neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Barium; Cadmium; Calcium; Choline; Evoked Potentials; Hippocampus; In Vitro Techniques; Interneurons; Ion Channels; Kinetics; Lidocaine; Male; Membrane Potentials; Neurons; Neurotoxins; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
Voltage clamp analysis of intact stomatogastric neurons.
Topics: 4-Aminopyridine; Animals; Calcium Channels; Electrophysiology; Ion Channels; Nephropidae; Neurons; Pylorus; Stomach; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
Functional properties of a slowly inactivating potassium current in guinea pig dorsal lateral geniculate relay neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Cats; Cell Membrane; Cerebral Cortex; Female; Geniculate Bodies; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Neurons; Potassium Channels; Tetraethylammonium Compounds; Tetrodotoxin; Thalamus | 1991 |
Muscarinic receptor activation induces a prolonged post-stimulus afterdepolarization with a conductance decrease in guinea-pig olfactory cortex neurones in vitro.
Topics: 4-Aminopyridine; Animals; Barium; Cerebral Cortex; Cesium; Electric Conductivity; Guinea Pigs; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons; Oxotremorine; Quaternary Ammonium Compounds; Receptors, Muscarinic; Smell; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
Modulatory effects of serotonin, FMRFamide, and myomodulin on the duration of action potentials, excitability, and membrane currents in tail sensory neurons of Aplysia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Aplysia; Arachidonic Acid; Cell Membrane; FMRFamide; Ganglia; In Vitro Techniques; Kinetics; Neurons, Afferent; Neuropeptides; Serotonin; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1991 |
Delayed potassium current and non-specific outward current in pyramidal neurones acutely dissociated from rat hippocampus.
Topics: 4-Aminopyridine; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Kinetics; Lanthanum; Membrane Potentials; Neurons; Potassium Channels; Pyramidal Tracts; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
A transient voltage-dependent outward potassium current in mammalian cerebellar Purkinje cells.
Topics: 4-Aminopyridine; Animals; Cerebellum; Cesium; Evoked Potentials; In Vitro Techniques; Kinetics; Neurons; Potassium Channels; Purkinje Cells; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
Whole-cell clamp of dissociated photoreceptors from the eye of Lima scabra.
Topics: 4-Aminopyridine; Animals; Barium; Bivalvia; Cadmium; Calcium Channels; Electrophysiology; Kinetics; Ocular Physiological Phenomena; Photic Stimulation; Photoreceptor Cells; Sodium Channels; Tetraethylammonium Compounds; Tetrodotoxin | 1991 |
Modulation of acetylcholine release from rat striatal slices: interaction between 4-aminopyridine and atropine.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Atropine; Corpus Striatum; Drug Interactions; Hippocampus; Homeostasis; Male; Oxotremorine; Potassium Channels; Rats; Rats, Inbred Strains; Tetrodotoxin | 1991 |
Regulation of transmitter release at the squid giant synapse by presynaptic delayed rectifier potassium current.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Animals; Cell Membrane Permeability; Decapodiformes; Ganglia, Sympathetic; In Vitro Techniques; Kinetics; Manganese; Neurotransmitter Agents; Potassium; Potassium Channels; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1990 |
Ethacrynic acid-induced glutamate release from mouse brain synaptosomes.
Topics: 4-Aminopyridine; Animals; Brain; Calcium; Dicyclohexylcarbodiimide; Ethacrynic Acid; Glutamates; Kinetics; Male; Mice; Mice, Inbred Strains; Ouabain; Synaptosomes; Tetrodotoxin | 1991 |
A study of the developmental changes in outward currents of rat ventricular myocytes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Barium; Barium Compounds; Cadmium; Chlorides; Heart; In Vitro Techniques; Kinetics; Potassium; Potassium Channels; Rats; Rats, Inbred Strains; Tetrodotoxin; Time Factors; Ventricular Function | 1990 |
Two transient outward currents in histamine neurones of the rat hypothalamus in vitro.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Histamine; Magnesium; Mammillary Bodies; Membrane Potentials; Potassium Channels; Rats; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1990 |
Effect of antiarrhythmic drugs, TTX, and 4-aminopyridine on repetitive electrical activity in frog skeletal muscle.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Electrophysiology; In Vitro Techniques; Kinetics; Muscles; Rana esculenta; Sodium Channels; Tetrodotoxin; Veratrine | 1990 |
The differentiation of excitability in embryonic chick limb motoneurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Chick Embryo; Electric Conductivity; Extremities; Motor Neurons; Muscles; Potassium Channels; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1990 |
Calcium-independent GABA release from striatal slices: the role of calcium channels.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channels; Corpus Striatum; gamma-Aminobutyric Acid; Magnesium; Male; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin; Verapamil | 1990 |
Ionic dependencies of tetrodotoxin-resistant action potentials in trigeminal root ganglion neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Cisplatin; Doxorubicin; Electrodes; Guinea Pigs; In Vitro Techniques; Lidocaine; Neurons; Potassium Channels; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Trigeminal Ganglion | 1990 |
4-Aminopyridine increases acetylcholine release without diminishing membrane phosphatidylcholine.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Calcium; Carbon Radioisotopes; Corpus Striatum; Hemicholinium 3; In Vitro Techniques; Male; Membranes; Phosphatidylcholines; Phospholipids; Rats; Rats, Inbred Strains; Tetrodotoxin; Verapamil | 1990 |
Potassium currents in rat cortical neurons in culture are enhanced by the antiepileptic drug carbamazepine.
Topics: 4-Aminopyridine; Animals; Cadmium; Calcium; Carbamazepine; Cells, Cultured; Cerebral Cortex; Ethanol; Female; Neurons; Potassium Channels; Pregnancy; Rats; Rats, Inbred Strains; Sodium; Tetrodotoxin | 1990 |
Current-clamp analysis of a time-dependent rectification in rat optic nerve.
Topics: 4-Aminopyridine; Action Potentials; Animals; Axons; Barium; Calcium Channel Blockers; Cesium; In Vitro Techniques; Neural Conduction; Optic Nerve; Potassium; Rats; Rats, Inbred Strains; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1990 |
Some characteristics of baclofen-evoked responses of primary afferents in frog spinal cord.
Topics: 4-Aminopyridine; Action Potentials; Animals; Baclofen; Barium; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons, Afferent; Potassium; Rana pipiens; Spinal Cord; Tetrodotoxin | 1990 |
Elevated potassium shortens action potential duration by altering outward currents in chick dorsal root ganglia neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Cells, Cultured; Chick Embryo; Ganglia, Spinal; Potassium; Tetraethylammonium Compounds; Tetrodotoxin | 1990 |
Evidence for the functional compartmentalization of spike generating regions of rat midbrain dopamine neurons recorded in vitro.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cobalt; Dopamine; Electrophysiology; Male; Membrane Potentials; Mesencephalon; Neurons; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1990 |
Changes in the ionic currents sensitivity to inhibitors in twitch rat skeletal muscles following denervation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Drug Resistance; Ion Channels; Muscle Denervation; Muscles; Permeability; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1985 |
Potentiation of a transient outward current by Na+ influx in crayfish neurones.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Astacoidea; Egtazic Acid; Ion Channels; Motor Neurons; Ouabain; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1985 |
Low-threshold, slow-inactivating Na+ potentials in the cockroach giant axon.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Axons; Calcium; Ion Channels; Male; Membrane Potentials; Periplaneta; Potassium; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1985 |
A transient outward current in isolated cells from the crista terminalis of rabbit heart.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Heart; In Vitro Techniques; Ion Channels; Kinetics; Myocardium; Potassium; Rabbits; Tetrodotoxin | 1985 |
Electrical activity of mouse motor endings during muscle reinnervation.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Ion Channels; Membrane Potentials; Mice; Motor Neurons; Nerve Regeneration; Potassium; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1985 |
Ion channels in rabbit cultured fibroblasts.
Topics: 4-Aminopyridine; Aminopyridines; Amphibian Proteins; Animals; Calcium; Carrier Proteins; Cells, Cultured; Chlorides; Fibroblasts; Ion Channels; Membrane Potentials; Potassium; Rabbits; Rats; Rats, Inbred Strains; Saxitoxin; Tetraethylammonium Compounds; Tetrodotoxin | 1986 |
Dendrotoxin: a selective blocker of a non-inactivating potassium current in guinea-pig dorsal root ganglion neurones.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Elapid Venoms; Ganglia, Spinal; Guinea Pigs; In Vitro Techniques; Ion Channels; Membrane Potentials; Potassium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1986 |
Currents under voltage clamp of burst-forming neurons of the cardiac ganglion of the lobster (Homarus americanus).
Topics: 4-Aminopyridine; Aminopyridines; Animals; Axons; Calcium; Electric Stimulation; Ganglia; Ion Channels; Membrane Potentials; Nephropidae; Neural Inhibition; Neurons; Potassium; Synaptic Transmission; Tetrodotoxin | 1986 |
Ionic channels in mouse astrocytes in culture.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Astrocytes; Cells, Cultured; Chlorides; Ion Channels; Membrane Potentials; Mice; Potassium; Scorpion Venoms; Sodium; Tetrodotoxin; Veratridine | 1987 |
Effects of tonicity on the pacemaker activity of guinea-pig sino-atrial node.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Atropine; Calcium; Cesium; Chlorides; Female; Guinea Pigs; Heart Rate; Ion Channels; Magnesium; Male; Membrane Potentials; Phentolamine; Potassium; Propranolol; Sinoatrial Node; Sodium; Sucrose; Tetraethylammonium Compounds; Tetrodotoxin | 1986 |
Immunocytochemical and electrophysiological differentiation of rat cerebellar granule cells in explant cultures.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Differentiation; Cells, Cultured; Cerebellum; Electric Conductivity; Glial Fibrillary Acidic Protein; Immunoenzyme Techniques; Ion Channels; Membrane Potentials; Phosphopyruvate Hydratase; Potassium; Rats; Rats, Inbred Strains; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1987 |
Repetitive inhibitory postsynaptic potentials evoked by 4-aminopyridine in hippocampal neurons in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Aminopyridines; Animals; Calcium; Fenclonine; Hippocampus; In Vitro Techniques; Interneurons; Isoproterenol; Male; Membrane Potentials; Neural Inhibition; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin | 1987 |
Function and distribution of three types of rectifying channel in rat spinal root myelinated axons.
Topics: 4-Aminopyridine; Action Potentials; Adaptation, Physiological; Aminopyridines; Animals; Axons; Barium; Cesium; Female; Ion Channels; Membrane Potentials; Potassium; Rats; Rats, Inbred Strains; Spinal Nerve Roots; Tetraethylammonium Compounds; Tetrodotoxin | 1987 |
Sodium currents in axon-associated Schwann cells from adult rabbits.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; In Vitro Techniques; Ion Channels; Microscopy, Electron; Nerve Fibers; Rabbits; Schwann Cells; Sciatic Nerve; Sodium; Tetrodotoxin; Time Factors | 1987 |
A whole-cell and single-channel study of the voltage-dependent outward potassium current in avian hepatocytes.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cells, Cultured; Chickens; Electric Conductivity; Electrophysiology; Ion Channels; Kinetics; Liver; Male; Membrane Potentials; Potassium; Tetrodotoxin | 1988 |
Calcium conductance and firing properties of spinal motoneurones in the turtle.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Apamin; Calcium; In Vitro Techniques; Ion Channels; Motor Neurons; Neuromuscular Depolarizing Agents; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Turtles | 1988 |
Ionic basis of the differential neuronal activity of guinea-pig septal nucleus studied in vitro.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Calcium; Cobalt; Guinea Pigs; In Vitro Techniques; Ion Channels; Membrane Potentials; Neurons; Septal Nuclei; Tetrodotoxin; Time Factors | 1988 |
Intrinsic properties of neurones in the dorsal cochlear nucleus of mice, in vitro.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Brain; Calcium; Cochlear Nerve; In Vitro Techniques; Ion Channels; Mice; Muscarine; Neurons; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1988 |
Mechanism of action of galanin on myenteric neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electrophysiology; Galanin; Guinea Pigs; Membrane Potentials; Myenteric Plexus; Neurons; Peptides; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1988 |
Cultured melanotrophs of the adult rat pituitary possess a voltage-activated fast transient outward current.
Topics: 4-Aminopyridine; Action Potentials; Animals; Barium; Cadmium; Cells, Cultured; Ion Channels; Pituitary Gland; Potassium; Quinine; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1989 |
A role for potassium channels in the regulation of cortical muscarinic acetylcholine receptors in an in vitro slice preparation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Carbachol; Cerebral Cortex; Electric Conductivity; Homeostasis; In Vitro Techniques; Kinetics; Male; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Veratridine | 1989 |
Classical conditioning reduces amplitude and duration of calcium-dependent afterhyperpolarization in rabbit hippocampal pyramidal cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cadmium; Cadmium Chloride; Calcium; Carbachol; Cobalt; Conditioning, Classical; Egtazic Acid; Electroshock; Hippocampus; In Vitro Techniques; Male; Pyramidal Tracts; Rabbits; Reference Values; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1989 |
Release of vasoactive intestinal peptide in mouse cerebral cortex: evidence for a role of arachidonic acid metabolites.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; Lipoxygenase Inhibitors; Male; Melitten; Mice; Quinacrine; Tetrodotoxin; Vasoactive Intestinal Peptide | 1989 |
K+-channel blockade in trigeminal root ganglion neurons: effects on membrane outward currents.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Membrane; Cesium; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Membrane Potentials; Neurons; Parasympathomimetics; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Trigeminal Ganglion; Trigeminal Nerve | 1989 |
Calcium-sensitive and insensitive transient outward current in rabbit ventricular myocytes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Caffeine; Calcium; Egtazic Acid; Heart; In Vitro Techniques; Membrane Potentials; Potassium; Rabbits; Ryanodine; Tetrodotoxin | 1989 |
Ca-mediated action potentials in ventricular myocardium. Variation by various stimulation patterns and by K-channel blockers.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Cesium; Chlorides; Heart; Isoproterenol; Myocardial Contraction; Papillary Muscles; Potassium Channels; Rabbits; Tetrodotoxin; Verapamil | 1989 |
Activation of protein kinase C by 4-aminopyridine dependent on Na+ channel activity in rat hippocampal slices.
Topics: 4-Aminopyridine; Animals; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; Metalloendopeptidases; Phosphorylation; Protein Kinases; Rats; Rats, Inbred Strains; Sodium Channels; Tetrodotoxin | 1989 |
Contributions of a transient outward current to repolarization in human atrium.
Topics: 4-Aminopyridine; Action Potentials; Aged; Atrial Function; Cadmium; Cadmium Chloride; Electric Conductivity; Electrophysiology; Heart; Heart Atria; Humans; In Vitro Techniques; Kinetics; Membrane Potentials; Middle Aged; Tetrodotoxin; Time Factors | 1989 |
4-Aminopyridine induces the release of neuropeptide Y (NPY) to produce an atropine- and tetrodotoxin-resistant contraction in rabbit isolated jejunum.
Topics: 4-Aminopyridine; Animals; Atropine; Drug Resistance; Female; In Vitro Techniques; Jejunum; L-Lactate Dehydrogenase; Male; Muscle Contraction; Muscle, Smooth; Neuropeptide Y; Rabbits; Radioimmunoassay; Synaptosomes; Tetrodotoxin | 1989 |
Investigations of excitability of isolated and non-isolated neurons from the terminal ganglion of Periplaneta americana by current/voltage clamp and intracellular perfusion.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cockroaches; Cycloheximide; Ganglia; In Vitro Techniques; Male; Motor Neurons; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1989 |
Effects of low concentrations of 4-aminopyridine on CA1 pyramidal cells of the hippocampus.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Bicuculline; Central Nervous System Stimulants; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin | 1989 |
Effects of cadmium on quantal transmitter release and ultrastructure of frog motor nerve endings.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Cadmium; Diaphragm; In Vitro Techniques; Male; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Rana esculenta; Respiratory Muscles; Synaptic Transmission; Tetrodotoxin | 1989 |
Barium action potentials in regenerating axons of the lamprey spinal cord.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Barium; Dose-Response Relationship, Drug; Electric Conductivity; Ion Channels; Isoquinolines; Lampreys; Microelectrodes; Nerve Regeneration; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1985 |
Light-evoked depolarizations in the retina of Strombus: role of sodium and potassium ions.
Topics: 4-Aminopyridine; Adaptation, Physiological; Aminopyridines; Animals; Hydrogen-Ion Concentration; Ion Channels; Lithium; Membrane Potentials; Neurons; Photic Stimulation; Potassium; Retina; Snails; Sodium; Tetrodotoxin | 1985 |
The slow calcium-dependent potassium current in a myenteric neurone of the guinea-pig ileum.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Calcium; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Myenteric Plexus; Neurons; Potassium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1985 |
Modulation of stimulation-evoked release of newly formed acetylcholine from mouse hemidiaphragm preparation.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine; Aminopyridines; Animals; Atropine; Calcium; Diaphragm; Electric Stimulation; In Vitro Techniques; Male; Mice; Neuromuscular Junction; Oxotremorine; Tetrodotoxin; Theophylline; Xylazine | 1987 |
Release of endogenous ATP during sympathetic nerve stimulation.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Phenylephrine; Prazosin; Sympathetic Nervous System; Tetrodotoxin; Vas Deferens | 1987 |
Differential effects of 4-aminopyridine and 2,4-diaminopyridine on the in vivo release of acetylcholine and dopamine in freely moving rats measured by intrastriatal dialysis.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Brain; Corpus Striatum; Dialysis; Dopamine; Injections; Male; Rats; Rats, Inbred Strains; Tetrodotoxin | 1988 |
Optical recording of electrical activity from axons and glia of frog optic nerve: potentiometric dye responses and morphometrics.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Benzenesulfonates; Electric Stimulation; Fluorescent Dyes; Neuroglia; Optic Nerve; Oxazoles; Oxazolone; Photic Stimulation; Rana pipiens; Spectrometry, Fluorescence; Spectrophotometry, Atomic; Tetrodotoxin | 1988 |
The development of voltage-dependent ionic conductances in murine spinal cord neurones in culture.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Axons; Calcium Channels; Cells, Cultured; Electric Conductivity; Embryo, Mammalian; Membrane Potentials; Mice; Mice, Inbred Strains; Neurons; Potassium Channels; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1988 |
The mode of action of 4-aminopyridine on the chronotropic and inotropic responses in the isolated, blood-perfused dog heart.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Dogs; Heart; Heart Rate; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Myocardial Contraction; Perfusion; Sinoatrial Node; Tetrodotoxin | 1985 |
Mechanism of the calcium-dependent stimulation of transmitter release by 4-aminopyridine in synaptosomes.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Brain; Calcium; Choline; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Sodium; Synaptosomes; Tetrodotoxin; Tritium | 1985 |
Quantal currents evoked by graded intracellular depolarization of crayfish motor axon terminals.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Astacoidea; Axons; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Motor Neurons; Neuromuscular Junction; Neurotransmitter Agents; Tetrodotoxin | 1987 |
The effect of Lambert-Eaton myasthenic syndrome antibody on slow action potentials in mouse cardiac ventricle.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium Channels; Heart; Heart Ventricles; Humans; Immunoglobulin G; In Vitro Techniques; Mice; Neuromuscular Diseases; Reference Values; Syndrome; Tetrodotoxin; Ventricular Function; Verapamil | 1988 |
Transmitter release at mouse motor nerve terminals mediated by temporary accumulation of intracellular barium.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Egtazic Acid; In Vitro Techniques; Magnesium; Mice; Motor Endplate; Muscles; Neomycin; Neuromuscular Junction; Neurotransmitter Agents; Ranidae; Tetrodotoxin; Time Factors | 1988 |
Ion dependence of the release of noradrenaline by tetraethylammonium and 4-aminopyridine from cat splenic slices.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Bicarbonates; Cations, Divalent; Cats; Guanidine; Guanidines; In Vitro Techniques; Norepinephrine; Perfusion; Spleen; Tetraethylammonium Compounds; Tetrodotoxin | 1985 |
Effects of cholinergic drugs and 4-aminopyridine on cat ciliary muscle contractility.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Carbachol; Cats; Ciliary Body; Muscle Contraction; Parasympathomimetics; Physostigmine; Tetrodotoxin | 1985 |
Atropine- and tetrodotoxin-resistant motor activity, responsive to 4-aminopyridine, present in isolated rabbit jejunum.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Drug Resistance; In Vitro Techniques; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Synaptic Transmission; Tetrodotoxin | 1985 |
4-Aminopyridine-induced changes in the electrical and contractile activities of the gastric smooth muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Cats; Electric Conductivity; Female; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Phentolamine; Propranolol; Stomach; Tetrodotoxin | 1985 |
Differential effects of Ca antagonists on the noradrenaline release and contraction evoked by nerve stimulation in the presence of 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Norepinephrine; Salicylates; Salicylic Acid; Stereoisomerism; Tetracaine; Tetrodotoxin; Verapamil | 1987 |
Potentiation by 4-aminopyridine of quantal acetylcholine release at the Torpedo nerve-electroplaque junction.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Aminopyridines; Animals; Calcium; Electric Organ; In Vitro Techniques; Magnesium; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Torpedo | 1986 |
Long-term modifiability of anomalous and delayed rectification in guinea pig inferior olivary neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cations; Electric Conductivity; Guinea Pigs; Harmaline; In Vitro Techniques; Membrane Potentials; Neurons; Olivary Nucleus; Potassium; Tetrodotoxin | 1987 |
[Effects of 3,4-diaminopyridine on the contractions of guinea-pig tracheal smooth muscle induced by histamine and prostaglandin D2].
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Drug Synergism; Guinea Pigs; Histamine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nifedipine; Prostaglandin D2; Prostaglandins D; Tetrodotoxin; Trachea | 1988 |
The potassium conductance of the resting squid axon and its blockage by clinical concentrations of general anaesthetics.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Anesthetics; Animals; Axons; Decapodiformes; In Vitro Techniques; Membrane Potentials; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1988 |
Presynaptic Na/Ca action potentials in unmyelinated axons of olfactory cortex.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Amygdala; Animals; Axons; Calcium; Calcium Channel Blockers; Cations, Divalent; Cerebral Cortex; Female; Guinea Pigs; In Vitro Techniques; Male; Potassium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1988 |
Effects of extracellular calcium and calcium channel blocker on silver-induced contractures in frog skeletal muscle fibers.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Drug Interactions; Morpholines; Muscle Contraction; Rana catesbeiana; Silver; Solutions; Tetrodotoxin | 1987 |
Presynaptic membrane potential and transmitter release at the crayfish neuromuscular junction.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Astacoidea; Calcium; Membrane Potentials; Models, Neurological; Neuromuscular Junction; Synaptic Transmission; Tetrodotoxin | 1984 |
Facilitatory effects of 4-aminopyridine on strontium-mediated evoked and delayed transmitter release from motor nerve terminals.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Anura; Electric Stimulation; In Vitro Techniques; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Rana esculenta; Strontium; Tetrodotoxin | 1982 |
Action potential in neurons of motor nerve net of Cyanea (Coelenterata).
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Cations, Divalent; Cnidaria; Motor Neurons; Nerve Net; Nervous System Physiological Phenomena; Refractory Period, Electrophysiological; Scyphozoa; Tetraethylammonium Compounds; Tetrodotoxin | 1983 |
Characteristics of inhibitory post-synaptic currents in brain-stem neurones of the lamprey.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Brain Stem; Calcium; Fishes; Glycine; In Vitro Techniques; Lampreys; Membrane Potentials; Neurons; Neurotransmitter Agents; Potassium; Receptors, Neurotransmitter; Tetrodotoxin | 1983 |
Muscarinic receptors and [3H]inositol incorporation in a rat sympathetic ganglion.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Bethanechol; Bethanechol Compounds; Cyclic GMP; Ganglia, Sympathetic; Hexamethonium; Hexamethonium Compounds; Inositol; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tetrodotoxin; Tritium | 1984 |
Substance P, bethanechol, 4-aminopyridine, and potassium antagonize the depressing effects of low-frequency stimulation, tetrodotoxin, procaine, and of magnesium on the field-stimulated guinea-pig vas deferens.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bethanechol Compounds; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Magnesium; Male; Muscle Contraction; Muscle, Smooth; Potassium; Procaine; Substance P; Tetrodotoxin; Vas Deferens | 1980 |
Increase of cGMP and accumulation of 45Ca2+ evoked by drugs acting on sodium or potassium channels.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cerebellum; Cyclic GMP; In Vitro Techniques; Ion Channels; Mice; Potassium; Scorpion Venoms; Sodium; Tetrodotoxin | 1981 |
Studies on the role of Na+, K+ and Cl- ion permeabilities in K+-induced release of 3H-noradrenaline from rat brain slices and synaptosomes and in its presynaptic alpha-adrenergic modulation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Brain; Chlorides; Electrolytes; In Vitro Techniques; Male; Norepinephrine; Potassium; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sodium; Synaptosomes; Tetrodotoxin | 1981 |
Membrane potential changes of mouse adrenal zona fasciculata cells in response to adrenocorticotropin and adenosine 3',5'-monophosphate.
Topics: 4-Aminopyridine; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aminopyridines; Animals; Cobalt; Cyclic AMP; Ion Channels; Male; Membrane Potentials; Mice; Tetrodotoxin | 1982 |
Enhancement of synaptic transmission by 4-aminopyridine in hippocampal slices of the rat.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Dendrites; Hippocampus; In Vitro Techniques; Intracellular Fluid; Male; Membrane Potentials; Neuromuscular Depolarizing Agents; Neurons; Rats; Synapses; Synaptic Transmission; Tetrodotoxin | 1982 |
Electronic properties of motor nerve terminals.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Evoked Potentials; Membrane Potentials; Motor Endplate; Motor Neurons; Neuromuscular Junction; Rana temporaria; Synaptic Transmission; Tetraethylammonium Compounds; Tetrodotoxin | 1982 |
Drugs affecting the calcium-dependent slow depolarization mechanism of the cardiac cell membrane.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Catecholamines; Cats; Electrocardiography; Female; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Ion Channels; Male; Myocardial Contraction; Prostaglandins; Serotonin; Sodium; Tetrodotoxin; Tissue Extracts | 1982 |
Intracellular ion control in lobster stretch receptor neurone.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Membrane Permeability; gamma-Aminobutyric Acid; Intracellular Fluid; Ion Channels; Ion Exchange; Mechanoreceptors; Models, Biological; Nephropidae; Neurons; Potassium; Sodium; Tetraethylammonium Compounds; Tetrodotoxin | 1983 |
Presynaptic currents in frog motor endings.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Electric Conductivity; Ion Channels; Motor Neurons; Nerve Endings; Rana esculenta; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1984 |
Rat hippocampal neurons in culture: potassium conductances.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cells, Cultured; Electrophysiology; Hippocampus; Ion Channels; Neurons; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1984 |
Effects of veratridine, tetrodotoxin and other drugs that alter electrical behaviour on secretion of melanocyte-stimulating hormone from melanotrophs of the pituitary pars intermedia.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium Channel Blockers; Cells, Cultured; Drug Interactions; Female; Melanocyte-Stimulating Hormones; Mice; Mice, Inbred Strains; Pituitary Gland, Anterior; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Veratridine; Veratrine | 1984 |
Effects of 4-aminopyridine on calcium action potentials and calcium current under voltage clamp in spinal neurons.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Fetus; Mice; Neuromuscular Depolarizing Agents; Neurons; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1983 |
Differential effects of strychnine on two types of vascular muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Aorta, Thoracic; Cardiovascular Agents; Male; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Prazosin; Rats; Rats, Inbred Strains; Strychnine; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Verapamil | 1984 |
Tetrodotoxin-resistant release of 3H-noradrenaline from the mouse vas deferens by high intensity electrical stimulation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cations, Divalent; Drug Resistance; Electric Stimulation; Male; Mice; Mice, Inbred Strains; Narcotics; Norepinephrine; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Tritium; Vas Deferens | 1984 |
Extracellular ions and excitation-contraction coupling in frog twitch muscle fibres.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Arsenazo III; Calcium; Chlorides; In Vitro Techniques; Muscle Contraction; Muscles; Potassium; Sarcoplasmic Reticulum; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1984 |
Effect of 4-aminopyridine on potassium permeability of canine tracheal smooth muscle cell membrane.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Cell Membrane Permeability; Dogs; Gallopamil; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth; Potassium; Radioisotopes; Rubidium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Trachea | 1983 |
The effects of 4-aminopyridine and tetrodotoxin on the release of acetylcholine from rat striatal slices.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Calcium; Corpus Striatum; Female; Male; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin | 1983 |
Contraction of the frog muscle in 4-aminopyridine by rapid cooling.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Caffeine; Cold Temperature; Dose-Response Relationship, Drug; In Vitro Techniques; Manganese; Membrane Potentials; Muscle Contraction; Neuromuscular Depolarizing Agents; Rana catesbeiana; Tetrodotoxin; Tubocurarine | 1981 |
Inward rectification in mouse macrophages: evidence for a negative resistance region.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cells, Cultured; Macrophages; Membrane Potentials; Mice; Mice, Inbred Strains; Neuromuscular Depolarizing Agents; Rubidium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1981 |
Effects of 4-aminopyridine on the adrenergic nerve terminals of rabbit arteries.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Arteries; Electric Stimulation; In Vitro Techniques; Male; Nerve Endings; Nicotine; Norepinephrine; Rabbits; Sympathetic Nervous System; Tetrodotoxin; Vasoconstriction | 1981 |
Dopamine release induced by electrical stimulation of microdissected caudate-putamen and substantia nigra of the rat brain.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Caudate Nucleus; Dopamine; Electric Stimulation; Male; Methods; Microsurgery; Putamen; Rats; Rats, Inbred Strains; Substantia Nigra; Tetrodotoxin | 1981 |
Ca-K bi-ionic action potential in squid giant axons.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Calcium; Cobalt; Decapodiformes; Gallopamil; Manganese; Membrane Potentials; Neuromuscular Depolarizing Agents; Potassium; Tetrodotoxin | 1981 |
Single voltage-activated Na+ and K+ channels in the somata of rat motoneurones.
Topics: 4-Aminopyridine; Animals; Elapid Venoms; Electrophysiology; Motor Neurons; Neurotoxins; Potassium Channels; Rats; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1995 |
Voltage-activated ionic currents in goldfish pituitary cells.
Topics: 4-Aminopyridine; Animals; Barium; Calcium Channels; Cells, Cultured; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; Goldfish; Ion Channels; Male; Membrane Potentials; Pituitary Gland; Potassium Channels; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
Ionic basis of the action potential of guinea pig gallbladder smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Action Potentials; Animals; Calcium Channels; Cell Membrane; Charybdotoxin; Electrophysiology; Female; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth; Nifedipine; Potassium Channel Blockers; Potassium Channels; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1993 |
Hyperpolarization-activated cation current (Ih) in neurons of the medial nucleus of the trapezoid body: voltage-clamp analysis and enhancement by norepinephrine and cAMP suggest a modulatory mechanism in the auditory brain stem.
Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acoustic Stimulation; Animals; Brain Stem; Cesium; Electrophysiology; In Vitro Techniques; Ion Channels; Iontophoresis; Male; Microelectrodes; Neurons; Norepinephrine; Pons; Potassium Channels; Rats; Tetrodotoxin | 1993 |
Effects of ion channel blockers and phorbol ester treatments on [3H]dopamine release and neurotensin facilitation of [3H]dopamine release from rat mesencephalic cells in primary culture.
Topics: 4-Aminopyridine; Amiloride; Animals; Apamin; Cells, Cultured; Dopamine; Ion Channels; Mesencephalon; Neurotensin; Nifedipine; omega-Conotoxin GVIA; Peptides; Phorbol Esters; Potassium; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Tritium | 1994 |
Effect of potassium channel blockade and alpha 2-adrenoceptor activation on the release of nitric oxide from non-adrenergic non-cholinergic nerves.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Animals; Arginine; Autonomic Nervous System; Brimonidine Tartrate; Charybdotoxin; Dogs; Electric Stimulation; Female; Male; Nitric Oxide; Nitroarginine; Potassium Channels; Quinoxalines; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Tetraethylammonium Compounds; Tetrodotoxin; Yohimbine | 1994 |
Axolemmal and septal conduction in the impedance of the earthworm medial giant nerve fiber.
Topics: 4-Aminopyridine; Amifampridine; Animals; Axons; Electric Stimulation; In Vitro Techniques; Ion Channels; Membrane Potentials; Models, Neurological; Models, Theoretical; Nerve Fibers; Neural Conduction; Oligochaeta; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1994 |
Origin of delayed outward ionic current in charge movement traces from frog skeletal muscle.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Aminopyridine; Amifampridine; Animals; Anions; Calcium; Cesium; Chloride Channels; Egtazic Acid; Furosemide; Gluconates; Glutamic Acid; Ion Channels; Muscle, Skeletal; Rana temporaria; Rubidium; Tetradecanoylphorbol Acetate; Tetrodotoxin; Time Factors | 1994 |
Ionic currents during action potentials in mammalian skeletal muscle fibers analyzed with loose patch clamp.
Topics: 4-Aminopyridine; Action Potentials; Animals; Ion Channels; Membrane Potentials; Mice; Muscle, Skeletal; Patch-Clamp Techniques; Tetraethylammonium Compounds; Tetrodotoxin | 1994 |
Characterization of a transient outward current in a rapidly adapting insect mechanosensory neuron.
Topics: 4-Aminopyridine; Action Potentials; Animals; Electrophysiology; In Vitro Techniques; Ion Channels; Kinetics; Mechanoreceptors; Membrane Potentials; Microelectrodes; Neurons, Afferent; Patch-Clamp Techniques; Periplaneta; Tetrodotoxin | 1994 |
A fast transient outward current in cultured cells from human pulmonary artery smooth muscle.
Topics: 4-Aminopyridine; Algorithms; Calcium Chloride; Cells, Cultured; Chi-Square Distribution; Evoked Potentials; Humans; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Chloride; Pulmonary Artery; Sodium; Tetrodotoxin; Time Factors | 1995 |
Regenerative properties of pyramidal cell dendrites in area CA1 of the rat hippocampus.
Topics: 4-Aminopyridine; Animals; Calcium; Electrophysiology; Hippocampus; Kinetics; Male; Membrane Potentials; Potassium Channel Blockers; Potassium Channels; Pyramidal Cells; Rats; Rats, Wistar; Regeneration; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1995 |
3,4-Diaminopyridine facilitates norepinephrine release in chick sympathetic neurons.
Topics: 4-Aminopyridine; Amifampridine; Animals; Calcium Channel Blockers; Calcium Channels; Chick Embryo; Ganglia, Sympathetic; Neurons; Norepinephrine; omega-Conotoxin GVIA; Peptides; Tetrodotoxin | 1995 |
Studies on the inhibition by chlorpromazine of myotonia induced by ion channel modulators in mouse skeletal muscle.
Topics: 4-Aminopyridine; Action Potentials; Animals; Chlorpromazine; Elapid Venoms; Ion Channels; Isotonic Solutions; Membrane Potentials; Mice; Mice, Inbred ICR; Microelectrodes; Muscles; Myotonia; Phospholipases A; Phospholipases A2; Tetrodotoxin; Veratridine | 1993 |
Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cobalt; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium Channels; Quinoxalines; Rats; Receptors, Amino Acid; Retina; Retinal Ganglion Cells; Sodium Channels; Strychnine; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
Prolonged time course of glutamate release from nerve terminals: relationship between stimulus duration and the secretory event.
Topics: 4-Aminopyridine; Action Potentials; Animals; Batrachotoxins; Calcium; Frontal Lobe; Glutamic Acid; Kinetics; Nerve Endings; Potassium Chloride; Rats; Sodium; Sodium Channels; Synaptosomes; Tetrodotoxin; Tritium | 1995 |
The effects of anticonvulsant compounds on 4-aminopyridine-induced de novo synthesis of neurotransmitter amino acids in rat hippocampus in vitro.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Glucose; Hippocampus; In Vitro Techniques; Male; Nerve Tissue Proteins; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Tetrodotoxin | 1995 |
Potassium currents responsible for inward and outward rectification in rat neostriatal spiny projection neurons.
Topics: 4-Aminopyridine; Animals; Barium Compounds; Calcium Chloride; Cesium; Chlorides; In Vitro Techniques; Ion Channel Gating; Male; Membrane Potentials; Models, Neurological; Neostriatum; Neurons; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1995 |
[Lithium-induced norepinephrine release from hippocampal slices in the absence of extracellular Ca2+].
Topics: 4-Aminopyridine; Amifampridine; Animals; Calcium; Drug Synergism; Hippocampus; In Vitro Techniques; Lithium; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1994 |
Resting and action potentials of nonischemic and chronically ischemic human ventricular muscle.
Topics: 4-Aminopyridine; Action Potentials; Chronic Disease; Diacetyl; Epinephrine; Heart; Humans; In Vitro Techniques; Membrane Potentials; Middle Aged; Myocardial Ischemia; Potassium; Tetrodotoxin | 1994 |
Voltage dependent fast calcium current in cultured skeletal myocytes of the frog Rana temporaria.
Topics: 4-Aminopyridine; Animals; Calcium Channels; Cells, Cultured; Embryo, Nonmammalian; Kinetics; Membrane Potentials; Muscle, Skeletal; Nifedipine; Patch-Clamp Techniques; Rana temporaria; Tetrodotoxin | 1994 |
Pharmacology and electrophysiology of a synchronous GABA-mediated potential in the human neocortex.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Humans; Male; Piperazines; Tetrodotoxin | 1994 |
Demonstration of voltage-dependent and TTX-sensitive Na(+)-channels in human melanocytes.
Topics: 4-Aminopyridine; Electric Conductivity; Humans; Male; Melanocytes; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Sodium; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1994 |
Effect of Na+ and K+ channel blockade on baseline and anoxia-induced catecholamine release from rat carotid body.
Topics: 4-Aminopyridine; Animals; Carotid Body; Catecholamines; Cesium; Electrophysiology; Hypoxia; Potassium Channel Blockers; Rats; Reference Values; Sodium Channel Blockers; Tetrodotoxin | 1994 |
Inhibition of K+ channel activity by 4-AP stimulates N-type Ca2+ channels in CHP-100 cells.
Topics: 4-Aminopyridine; Brain Neoplasms; Calcium; Calcium Channel Agonists; Calcium Channels; Cell Membrane; Humans; Neuroblastoma; Nifedipine; omega-Conotoxin GVIA; Peptides; Potassium Channels; Rubidium Radioisotopes; Synaptosomes; Tetrodotoxin; Tumor Cells, Cultured | 1994 |
Tetraethylammonium selectively stimulates secretion from noradrenergic bovine chromaffin cells.
Topics: 4-Aminopyridine; Animals; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Drug Interactions; Drug Synergism; Epinephrine; Glyburide; Nifedipine; Norepinephrine; Ouabain; Phorbol 12,13-Dibutyrate; Potassium Channel Blockers; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Tolbutamide | 1994 |
Studies on the role of K+, Cl- and Na+ ion permeabilities in the acetylcholine release enhancing effects of linopirdine (DuP 996) in rat cortical slices.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Aminopyridine; Acetylcholine; Amifampridine; Animals; Cerebral Cortex; Chlorides; In Vitro Techniques; Indoles; Male; Permeability; Potassium; Pyridines; Rats; Rats, Wistar; Sodium; Tetraethylammonium Compounds; Tetrodotoxin | 1994 |
Co-release of noradrenaline and ATP from cultured sympathetic neurons.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Chick Embryo; Epinephrine; Exocytosis; Ganglia, Sympathetic; Neurons; omega-Conotoxin GVIA; Peptides; Sympathetic Fibers, Postganglionic; Tetrodotoxin; Time Factors | 1994 |
Voltage-gated currents in rabbit retinal astrocytes.
Topics: 4-Aminopyridine; Animals; Astrocytes; Choline; Electric Conductivity; Electrophysiology; In Vitro Techniques; Male; Membrane Potentials; Potassium Channel Blockers; Rabbits; Retina; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1994 |
Effect of the putative cognitive enhancer, linopirdine (DuP 996), on quantal parameters of acetylcholine release at the frog neuromuscular junction.
Topics: 4-Aminopyridine; Acetylcholine; Alzheimer Disease; Animals; Calcium; Dose-Response Relationship, Drug; In Vitro Techniques; Indoles; Neuromuscular Junction; omega-Conotoxin GVIA; Peptides; Pyridines; Rana pipiens; Tetrodotoxin | 1994 |
Time-related loss of glutamine from hippocampal slices and concomitant changes in neurotransmitter amino acids.
Topics: 4-Aminopyridine; Amino Acids; Animals; Glutamates; Glutamic Acid; Glutamine; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Osmolar Concentration; Tetrodotoxin; Time Factors | 1993 |
Kinetic basis for the voltage-dependent inhibition of N-type calcium current by somatostatin and norepinephrine in chick sympathetic neurons.
Topics: 4-Aminopyridine; Amifampridine; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cesium; Chick Embryo; Electric Stimulation; Ganglia, Sympathetic; GTP-Binding Proteins; Kinetics; Membrane Potentials; Neurons; Norepinephrine; omega-Conotoxins; Peptides; Pertussis Toxin; Second Messenger Systems; Somatostatin; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors; Virulence Factors, Bordetella | 1993 |
Adenosine decreases action potential duration by modulation of A-current in rat locus coeruleus neurons.
Topics: 4-Aminopyridine; Action Potentials; Adenosine; Animals; Barium; Cesium; Electric Conductivity; Locus Coeruleus; Male; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1994 |
Role of sodium-calcium exchange in activation of contraction in rat ventricle.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channels; Electric Impedance; In Vitro Techniques; Ion Transport; Male; Membrane Potentials; Myocardial Contraction; Myocardium; Potassium; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Sodium; Tetrodotoxin | 1993 |
Contribution of a slowly inactivating potassium current to the transition to firing of neostriatal spiny projection neurons.
Topics: 4-Aminopyridine; Animals; Corpus Striatum; Culture Techniques; Dendrites; Dose-Response Relationship, Drug; Elapid Venoms; Electric Stimulation; Evoked Potentials; Male; Membrane Potentials; Neurons; Neurotoxins; Potassium Channels; Rats; Rats, Sprague-Dawley; Reaction Time; Synaptic Transmission; Tetrodotoxin | 1994 |
Transducer properties of the rapidly adapting stretch receptor neurone in the crayfish (Pacifastacus leniusculus).
Topics: 4-Aminopyridine; Adaptation, Physiological; Animals; Astacoidea; Cations, Divalent; Electric Stimulation; Electrophysiology; In Vitro Techniques; Mechanoreceptors; Membrane Potentials; Microelectrodes; Neurons; Permeability; Signal Transduction; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
Control of resting membrane potential by delayed rectifier potassium currents in ferret airway smooth muscle cells.
Topics: 4-Aminopyridine; Animals; Atropine; Electrophysiology; Female; Ferrets; In Vitro Techniques; Indicators and Reagents; Kinetics; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Nystatin; Potassium Channels; Temperature; Tetrodotoxin; Trachea | 1993 |
A study of the barium-sensitive and -insensitive components of the action of thyrotropin-releasing hormone on lumbar motoneurons of the rat isolated spinal cord.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Apamin; Barium; Cations, Divalent; Cells, Cultured; Cesium; Electric Conductivity; Electric Stimulation; Evoked Potentials; Female; Male; Motor Neurons; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Thyrotropin-Releasing Hormone | 1993 |
Sodium, calcium and late potassium currents are reduced in cerebellar granule cells cultured in the presence of a protein complex conferring resistance to excitatory amino acids.
Topics: 4-Aminopyridine; Animals; Calcium Channels; Cells, Cultured; Cerebellum; Drug Resistance; Kinetics; Membrane Potentials; Nerve Growth Factors; Neurons; Neurotoxins; Potassium Channels; Rats; Rats, Wistar; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
Release of cholecystokinin-like immunoreactivity in the frontal cortex of conscious rats as assessed by transcerebral microdialysis: effects of different depolarizing stimuli.
Topics: 4-Aminopyridine; Animals; Calcium; Cholecystokinin; Dialysis; Electrophysiology; Frontal Lobe; Male; Potassium; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Veratrine | 1993 |
Pituitary adenylate cyclase-activating peptide is a potent modulator of human colonic motility.
Topics: 4-Aminopyridine; Apamin; Arginine; Carbachol; Colon, Sigmoid; Gastrointestinal Motility; Humans; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Neuropeptides; Nitric Oxide; Nitroarginine; Phosphodiesterase Inhibitors; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Vasoactive Intestinal Peptide | 1993 |
Multiple types of calcium channels in acutely isolated rat neostriatal neurons.
Topics: 4-Aminopyridine; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Chloride; Corpus Striatum; Electric Stimulation; Electrophysiology; Fura-2; In Vitro Techniques; Male; Membrane Potentials; Neurons; Nimodipine; omega-Conotoxins; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1993 |
Kinetic study and numerical reconstruction of A-type current in granule cells of rat cerebellar slices.
Topics: 4-Aminopyridine; Animals; Barium; Cerebellum; Cesium; Cytoplasmic Granules; Electrophysiology; In Vitro Techniques; Kinetics; Models, Neurological; Neurons; Potassium; Potassium Channels; Rats; Sodium Channels; Tetrodotoxin | 1993 |
Physiological and morphological properties of accumbens core and shell neurons recorded in vitro.
Topics: 4-Aminopyridine; Action Potentials; Afferent Pathways; Animals; Axons; Calcium; Cobalt; Dendrites; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Male; Nerve Fibers; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Time Factors | 1993 |
Characteristic firing behavior of cell types in the cardiorespiratory region of the nucleus tractus solitarii of the rat.
Topics: 4-Aminopyridine; Animals; Electric Stimulation; Electrophysiology; In Vitro Techniques; Male; Medulla Oblongata; Membrane Potentials; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1993 |
Characteristics of a fast transient outward current in guinea pig trigeminal motoneurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Electrophysiology; Guinea Pigs; In Vitro Techniques; Manganese; Membrane Potentials; Motor Neurons; Patch-Clamp Techniques; Tetraethylammonium Compounds; Tetrodotoxin; Trigeminal Nuclei | 1995 |
Voltage-dependent Ca2+ channels in the spiral ganglion cells of guinea pig cochlea.
Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Calcium Channels; Cesium; Choline; Cochlea; Guinea Pigs; Membrane Potentials; Metals; Patch-Clamp Techniques; Reference Standards; Spiral Ganglion; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1995 |
Evidence for the induction of repetitive action potentials in synaptosomes by K+-channel inhibitors: an analysis of plasma membrane ion fluxes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cell Membrane; Charybdotoxin; Elapid Venoms; Fura-2; Guinea Pigs; Ion Channels; Peptides; Potassium Channel Blockers; Rubidium Radioisotopes; Synaptosomes; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Veratridine | 1996 |
Developmental and activity-dependent changes in K+ currents in satellite glial cells in mouse superior cervical ganglion.
Topics: 4-Aminopyridine; Aging; Animals; Barium; Cells, Cultured; Ion Channel Gating; Membrane Potentials; Mice; Mice, Inbred BALB C; Neuroglia; Patch-Clamp Techniques; Potassium Channels; Quinine; Superior Cervical Ganglion; Tetrodotoxin | 1996 |
Potassium currents in periglomerular cells of frog olfactory bulb in vitro.
Topics: 4-Aminopyridine; Animals; Anura; Cadmium; Calcium; In Vitro Techniques; Interneurons; Membrane Potentials; Olfactory Bulb; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1996 |
Characterization of TTX-resistant persistent Na+ current underlying pacemaker potentials of fish gonadotropin-releasing hormone (GnRH) neurons.
Topics: 4-Aminopyridine; Animals; Biological Clocks; Electrophysiology; Female; Fishes; Gonadotropin-Releasing Hormone; In Vitro Techniques; Lithium; Male; Meninges; Neurons; Patch-Clamp Techniques; Sodium Channels; Tetrodotoxin | 1996 |
4-Aminopyridine antagonizes saxitoxin-and tetrodotoxin-induced cardiorespiratory depression.
Topics: 4-Aminopyridine; Animals; Blood Gas Analysis; Blood Pressure; Bradycardia; Carbon Dioxide; Diaphragm; Electrocardiography; Electromyography; Electrophysiology; Guinea Pigs; Hydrogen-Ion Concentration; Hypotension; Infusions, Intravenous; Male; Neurons; Oxygen Consumption; Saxitoxin; Synaptic Transmission; Tetrodotoxin | 1996 |
Membrane properties of area postrema neurons.
Topics: 4-Aminopyridine; Action Potentials; Angiotensin II; Animals; Arginine Vasopressin; Brain Stem; Cell Membrane; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channel Blockers; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Vasoconstrictor Agents | 1995 |
A tetrodotoxin-insensitive [corrected] sodium current initiates burst firing of neocortical neurons.
Topics: 4-Aminopyridine; Alpha Rhythm; Animals; Cerebral Cortex; Evoked Potentials; Guinea Pigs; Neurons; Sodium Channels; Tetrodotoxin | 1996 |
Membrane properties of complex spike firing neurons of the mouse dorsal cochlear nucleus in vitro.
Topics: 4-Aminopyridine; Action Potentials; Animals; Auditory Pathways; Calcium Channel Blockers; Cochlear Nucleus; In Vitro Techniques; Mice; Mice, Inbred BALB C; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Verapamil | 1996 |
Voltage-gated ionic currents and their roles in timing coding in auditory neurons of the nucleus magnocellularis of the chick.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium Channels; Chick Embryo; Cochlear Nucleus; Evoked Potentials, Auditory, Brain Stem; Ion Channel Gating; Ion Channels; Kinetics; Neurons, Afferent; Nickel; Potassium Channel Blockers; Potassium Channels; Sodium Channels; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors; Vestibulocochlear Nerve | 1996 |
Membrane properties of mouse anteroventral cochlear nucleus neurons in vitro.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium Channel Blockers; Cochlear Nucleus; Electrophysiology; In Vitro Techniques; Mice; Mice, Inbred BALB C; Patch-Clamp Techniques; Tetraethylammonium Compounds; Tetrodotoxin; Verapamil | 1996 |
4-Aminopyridine effects on summating potentials in the guinea pig.
Topics: 4-Aminopyridine; Acoustic Stimulation; Analysis of Variance; Animals; Basilar Membrane; Cochlear Microphonic Potentials; Electric Conductivity; Female; Guinea Pigs; Hair Cells, Auditory, Inner; Hair Cells, Auditory, Outer; Potassium Channel Blockers; Signal Transduction; Tetrodotoxin; Tympanic Membrane; Vestibule, Labyrinth | 1996 |
Voltage-gated currents in identified parasympathetic cardiac neurons in the nucleus ambiguus.
Topics: 4-Aminopyridine; Animals; Autonomic Fibers, Preganglionic; Evoked Potentials; Heart; Ion Channel Gating; Medulla Oblongata; Membrane Potentials; Neural Inhibition; Neurons; Parasympathetic Nervous System; Potassium Channels; Rats; Sodium Channels; Synaptic Transmission; Tetrodotoxin | 1996 |
The effects of D-23129, a new experimental anticonvulsant drug, on neurotransmitter amino acids in the rat hippocampus in vitro.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamates; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Nerve Tissue Proteins; Neurotransmitter Agents; Phenylenediamines; Rats; Rats, Inbred Strains; Tetrodotoxin | 1995 |
Sodium effects on 4-aminopyridine-sensitive transient outward current in canine ventricular cells.
Topics: 4-Aminopyridine; Animals; Dogs; Electric Conductivity; Female; Ion Channel Gating; Ion Channels; Kinetics; Male; Myocardium; Patch-Clamp Techniques; Potassium; Sodium; Tetrodotoxin; Ventricular Function | 1997 |
Apamin blocks the direct relaxant effect of melatonin on rat ileal smooth muscle.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Apamin; Calcium; Calcium Channel Blockers; Carbachol; Cholinergic Antagonists; Glyburide; Hexamethonium; Humans; Ileum; Male; Melatonin; Muscarinic Antagonists; Muscle Contraction; Neuromuscular Depolarizing Agents; Nitrendipine; Phentolamine; Rats; Rats, Wistar; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Verapamil | 1997 |
ATP and [3H]noradrenaline release and the presence of ecto-Ca(2+)-ATPases in the capsule-glomerulosa fraction of the rat adrenal gland.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Adrenal Glands; Adrenergic alpha-Antagonists; Animals; Berberine; Calcium-Transporting ATPases; Electric Stimulation; Glyburide; Histocytochemistry; Male; Microscopy, Electron; Norepinephrine; Organ Culture Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Tetrodotoxin; Tritium | 1997 |
Sustained outward rectification of oxytocinergic neurones in the rat supraoptic nucleus: ionic dependence and pharmacology.
Topics: 4-Aminopyridine; Action Potentials; Animals; Barium; Calcium; Electrophysiology; Female; Lactation; Muscarine; Muscarinic Agonists; Neurons; Oxytocin; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Supraoptic Nucleus; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1997 |
Slow sodium-dependent potential oscillations contribute to ectopic firing in mammalian demyelinated axons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Axons; Demyelinating Diseases; Electrophysiology; Male; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Sciatic Nerve; Sodium Channels; Spinal Cord; Tetrodotoxin | 1997 |
Sapecin B, a novel fly toxin, blocks macroscopic K+ currents in the GH3 rat pituitary cell line.
Topics: 4-Aminopyridine; Animals; Charybdotoxin; Diptera; Insect Proteins; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; Patch-Clamp Techniques; Pituitary Gland, Anterior; Pituitary Neoplasms; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Scorpion Venoms; Tetrodotoxin; Time Factors; Tumor Cells, Cultured | 1997 |
4-Aminopyridine reverses saxitoxin (STX)- and tetrodotoxin (TTX)-induced cardiorespiratory depression in chronically instrumented guinea pigs.
Topics: 4-Aminopyridine; Animals; Bradycardia; Diaphragm; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Electroencephalography; Electromyography; Electrophysiology; Guinea Pigs; Heart Rate; Male; Neck Muscles; Respiration; Saxitoxin; Tetrodotoxin | 1997 |
Presynaptic calcium channels and field-evoked transmitter exocytosis from cultured cerebellar granule cells.
Topics: 4-Aminopyridine; Animals; Anti-Bacterial Agents; Aspartic Acid; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebellum; Electric Stimulation; Enzyme Inhibitors; Evoked Potentials; Exocytosis; Ion Channel Gating; Macrolides; Neurons; Potassium Chloride; Presynaptic Terminals; Rats; Rats, Wistar; Tetanus Toxin; Tetrodotoxin; Tritium | 1997 |
Ouabain-sensitive K(+)-dependent outward current caused by threo-beta-hydroxy-L-glutamic acid on a snail neuron.
Topics: 4-Aminopyridine; Amiloride; Animals; Dopamine; Glutamates; In Vitro Techniques; Membrane Potentials; Neurons; Neuropeptides; Neurotransmitter Agents; Ouabain; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Snails; Synaptic Transmission; Tetraethylammonium; Tetrodotoxin | 1997 |
Effects of Pb2+ on delayed-rectifier potassium channels in acutely isolated hippocampal neurons.
Topics: 4-Aminopyridine; Animals; Delayed Rectifier Potassium Channels; Guinea Pigs; Hippocampus; In Vitro Techniques; Lead; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Pyramidal Cells; Tetraethylammonium; Tetrodotoxin | 1997 |
Ionic mechanisms of intrinsic oscillations in neurons of the basolateral amygdaloid complex.
Topics: 4-Aminopyridine; Amygdala; Animals; Apamin; Barium; Calcium; Cations, Divalent; Cesium; Charybdotoxin; Egtazic Acid; Evoked Potentials; Fourier Analysis; Guinea Pigs; In Vitro Techniques; Magnesium; Membrane Potentials; Neurons; Oscillometry; Peptides; Sodium; Tetraethylammonium; Tetrodotoxin | 1998 |
Firing properties of spherical bushy cells in the anteroventral cochlear nucleus of the gerbil.
Topics: 4-Aminopyridine; Action Potentials; Animals; Auditory Threshold; Barium; Calcium; Cell Size; Cochlear Nucleus; Gerbillinae; Ion Channels; Microscopy, Interference; Patch-Clamp Techniques; Potassium; Sodium; Tetraethylammonium; Tetrodotoxin | 1997 |
Modulation of bursts and high-threshold calcium spikes in neurons of rat auditory thalamus.
Topics: 4-Aminopyridine; Animals; Auditory Pathways; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Evoked Potentials; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Reaction Time; Tetraethylammonium; Tetrodotoxin; Thalamus | 1998 |
Na+ channel block prevents the ischemia-induced release of norepinephrine from spinal cord slices.
Topics: 4-Aminopyridine; Anesthetics, Local; Animals; Calcium; Calcium Channel Blockers; Cold Temperature; Hypoglycemia; Hypoxia; Ischemia; Lidocaine; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Spinal Cord; Tetrodotoxin | 1998 |
Ca2+ and K+ currents regulate accommodation and firing frequency in guinea pig bronchial ganglion neurons.
Topics: 4-Aminopyridine; Animals; Apamin; Barium Compounds; Bronchi; Calcium Channel Blockers; Calcium Channels; Chlorides; Electrophysiology; Ganglia, Parasympathetic; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Neurons; Nifedipine; omega-Conotoxin GVIA; Peptides; Potassium Channel Blockers; Potassium Channels; Tetrodotoxin; Verapamil | 1998 |
GABA-dependent generation of ectopic action potentials in the rat hippocampus.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Piperazines; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Time Factors | 1998 |
Ionic currents in normal and neurofibromatosis type 1-affected human Schwann cells: induction of tumor cell K current in normal Schwann cells by cyclic AMP.
Topics: 4-Aminopyridine; Adolescent; Bucladesine; Cauda Equina; Cells, Cultured; Child; Colforsin; Cyclic AMP; Humans; Ion Channels; Membrane Potentials; Neurofibromatosis 1; Patch-Clamp Techniques; Potassium; Potassium Channels; Schwann Cells; Sodium; Tetraethylammonium; Tetrodotoxin; Thionucleotides; Tumor Cells, Cultured | 1998 |
Intrinsic oscillations in CA3 hippocampal pyramids: physiological relevance to theta rhythm generation.
Topics: 4-Aminopyridine; Aging; Animals; Animals, Newborn; Calcium; Calcium Channels; Carbachol; Cesium; Hippocampus; In Vitro Techniques; Membrane Potentials; Nifedipine; Oscillometry; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Rats; Rats, Wistar; Tetraethylammonium; Tetrodotoxin; Theta Rhythm | 1998 |
Spontaneous Na+ and Ca2+ spike firing of cerebellar Purkinje neurons at high pressure.
Topics: 4-Aminopyridine; Animals; Atmospheric Pressure; Calcium Channel Blockers; Calcium Channels; Cerebellum; Electric Stimulation; Electrophysiology; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Purkinje Cells; Sodium Channels; Tetrodotoxin | 1999 |
The pH-sensitive dye acridine orange as a tool to monitor exocytosis/endocytosis in synaptosomes.
Topics: 4-Aminopyridine; Acids; Acridine Orange; Animals; Anti-Bacterial Agents; Biological Transport; Cadmium; Calcium; Cerebral Cortex; Chelating Agents; Dimerization; Egtazic Acid; Endocytosis; Exocytosis; Fluorescent Dyes; Glutamic Acid; Hydrogen-Ion Concentration; Macrolides; Neurons; Neurotransmitter Agents; Potassium Chloride; Rats; Synaptic Vesicles; Synaptosomes; Tetrodotoxin | 1999 |
Ca2+-activated outward currents in neostriatal neurons.
Topics: 4-Aminopyridine; Animals; Apamin; Barium; Cadmium; Calcium; Charybdotoxin; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Neostriatum; Neurons; Patch-Clamp Techniques; Peptides; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Tetraethylammonium; Tetrodotoxin | 1999 |
Ionic mechanism of isoflurane's actions on thalamocortical neurons.
Topics: 4-Aminopyridine; Action Potentials; Anesthetics, Inhalation; Animals; Baclofen; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Conductivity; Female; GABA Agonists; Glyburide; Hypoglycemic Agents; Isoflurane; Male; Neurons; Parasympathomimetics; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Synapses; Tacrine; Tetraethylammonium; Tetrodotoxin; Thalamus | 1999 |
Nanomolar concentrations of lead inhibit glutamatergic and GABAergic transmission in hippocampal neurons.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Edetic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kinetics; Lead; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Channels; Sodium Channels; Synaptic Transmission; Tetrodotoxin | 1999 |
Increased excitability of afferent neurons innervating rat urinary bladder after chronic bladder inflammation.
Topics: 4-Aminopyridine; Action Potentials; Animals; Chronic Disease; Cyclophosphamide; Cystitis; Female; Ganglia, Spinal; Membrane Potentials; Nerve Fibers; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Urinary Bladder | 1999 |
Presynaptic muscarinic (M3) receptors reduce excitatory transmission in dopamine neurons of the rat mesencephalon.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Atropine; Carbachol; Diamines; Dicyclomine; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Mesencephalon; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Parasympatholytics; Physostigmine; Piperidines; Pirenzepine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Receptor, Muscarinic M3; Receptors, Muscarinic; Synaptic Transmission; Tetrodotoxin | 1999 |
Control of glutamate release by calcium channels and kappa-opioid receptors in rodent and primate striatum.
Topics: 4-Aminopyridine; Animals; Benzofurans; Calcium Channel Blockers; Calcium Channels; Callithrix; Glutamic Acid; In Vitro Techniques; Male; Naltrexone; Narcotic Antagonists; Neostriatum; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Spider Venoms; Synaptosomes; Tetrodotoxin | 1999 |
Glutamate receptors mediate TTX-resistant synchronous activity in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Action Potentials; Animals; Axons; Drug Resistance; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Neurons; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sodium; Sodium Channels; Synapses; Synaptic Transmission; Tetraethylammonium; Tetrodotoxin | 1999 |
Cu2+ induces Ca2+-dependent neurotransmitter release from brain catecholaminergic nerve terminals.
Topics: 4-Aminopyridine; Animals; Brain; Calcium; Catecholamines; Cations, Divalent; Copper; Dopamine; Dose-Response Relationship, Drug; Male; Metals, Heavy; Nerve Endings; Neurotransmitter Agents; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley; Synaptosomes; Tetrodotoxin; Time Factors | 1999 |
[Variations in the ionic currents as dependent on the size of the sensory neurons in newborn rats].
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Cell Membrane; Ganglia, Spinal; Ion Channels; Neurons, Afferent; Neurotoxins; Rats; Tetraethylammonium; Tetrodotoxin | 1999 |
Purkinje cell inhibitory responses to 3-APPA (3-aminopropylphosphinic acid) in RAT cerebellar slices.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Cerebellum; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Purkinje Cells; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1999 |
Physiological properties of central medial and central lateral amygdala neurons.
Topics: 4-Aminopyridine; Amygdala; Animals; Evoked Potentials; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Tetrodotoxin; Time Factors | 1999 |
Dendritic voltage-gated ion channels regulate the action potential firing mode of hippocampal CA1 pyramidal neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cadmium Chloride; Calcium Channel Blockers; Calcium Channels; Dendrites; Hippocampus; In Vitro Techniques; Nickel; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1999 |
Delayed rectifier and Ca(2+)-dependent K(+) currents in human esophagus: roles in regulating muscle contraction.
Topics: 4-Aminopyridine; Calcium; Charybdotoxin; Delayed Rectifier Potassium Channels; Electric Conductivity; Esophagus; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Peptides; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Reverse Transcriptase Polymerase Chain Reaction; Tetraethylammonium; Tetrodotoxin | 1999 |
Modulation of burst frequency, duration, and amplitude in the zero-Ca(2+) model of epileptiform activity.
Topics: 4-Aminopyridine; Animals; Barium; Calcium; Calibration; Cesium; Electric Stimulation; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; Models, Neurological; Neurons; Potassium; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetrodotoxin | 1999 |
Zinc modulation of ionic currents in the horizontal limb of the diagonal band of Broca.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channel Blockers; Cations, Divalent; Diagonal Band of Broca; Evoked Potentials; In Vitro Techniques; Male; Neurons; Nimodipine; omega-Conotoxins; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Sodium; Tetrodotoxin; Zinc | 1999 |
Different discharge properties of rat facial nucleus motoneurons.
Topics: 4-Aminopyridine; Animals; Brain Stem; Calcium; Carbachol; Electric Stimulation; Evoked Potentials; Facial Nerve; In Vitro Techniques; Motor Neurons; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1999 |
Pharmacological characterization of ionic currents that regulate the pacemaker rhythm in a weakly electric fish.
Topics: 4-Aminopyridine; Action Potentials; Animals; Biological Clocks; Cadmium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Conotoxins; Dose-Response Relationship, Drug; Electric Fish; Electric Organ; In Vitro Techniques; Neurons; Nickel; Nifedipine; Potassium Channel Blockers; Potassium Channels; Sodium Channel Blockers; Sodium Channels; Tetraethylammonium; Tetrodotoxin | 2000 |
Developmental changes in the expression of Shaker- and Shab-related K(+) channels in neurons of the rat trigeminal ganglion.
Topics: 4-Aminopyridine; Animals; Cadmium Chloride; Delayed Rectifier Potassium Channels; Elapid Venoms; Embryo, Mammalian; Female; Gene Expression Regulation, Developmental; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Pregnancy; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Scorpion Venoms; Shab Potassium Channels; Shaker Superfamily of Potassium Channels; Tetraethylammonium; Tetrodotoxin; Trigeminal Ganglion | 1999 |
Cellular and synaptic effect of substance P on neonatal phrenic motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Brain Stem; Cesium; Cobalt; Decerebrate State; Membrane Potentials; Motor Neurons; Patch-Clamp Techniques; Phrenic Nerve; Potassium Channels; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Spinal Cord; Substance P; Synapses; Tetraethylammonium; Tetrodotoxin | 2000 |
Low-voltage-activated calcium current does not regulate the firing behavior in paired mechanosensory neurons with different adaptation properties.
Topics: 4-Aminopyridine; Action Potentials; Adaptation, Physiological; Animals; Barium; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Female; Kinetics; Male; Mechanoreceptors; Neurons, Afferent; Nickel; Nifedipine; omega-Conotoxin GVIA; Patch-Clamp Techniques; Spiders; Tetraethylammonium; Tetrodotoxin | 2000 |
Expression of Kv1 potassium channels in mouse hippocampal primary cultures: development and activity-dependent regulation.
Topics: 4-Aminopyridine; Animals; Axons; Botulinum Toxins, Type A; Cells, Cultured; Delayed Rectifier Potassium Channels; Dentate Gyrus; Fetus; gamma-Aminobutyric Acid; Kv1.1 Potassium Channel; Kv1.2 Potassium Channel; Kv1.3 Potassium Channel; Kv1.4 Potassium Channel; Membrane Potentials; Membrane Proteins; Mice; Mice, Inbred Strains; Microscopy, Electron; Nerve Tissue Proteins; Neuroglia; Neuromuscular Agents; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Pyramidal Cells; R-SNARE Proteins; Synaptosomal-Associated Protein 25; Tetanus Toxin; Tetrodotoxin | 2000 |
Ionic currents in cardiac myocytes of squid, Alloteuthis subulata.
Topics: 4-Aminopyridine; Animals; Apamin; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Separation; Cells, Cultured; Decapodiformes; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Sodium; Tetraethylammonium; Tetrodotoxin | 2000 |
Diverse ionic currents and electrical activity of cultured myenteric neurons from the guinea pig proximal colon.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cells, Cultured; Colon; Electrophysiology; Guinea Pigs; In Vitro Techniques; Ion Channels; Male; Myenteric Plexus; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Tetraethylammonium; Tetrodotoxin | 2000 |
Histamine H(3) receptors mediate inhibition of noradrenaline release from intestinal sympathetic nerves.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Calcium; Colforsin; Dose-Response Relationship, Drug; Ethylmaleimide; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Ileum; In Vitro Techniques; Intestinal Mucosa; Intestines; Male; Muscle, Smooth; Myenteric Plexus; Nifedipine; Norepinephrine; omega-Conotoxins; Pertussis Toxin; Phenols; Receptors, Histamine H3; Rolipram; Sympathetic Nervous System; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine | 2000 |
Properties of voltage-gated potassium currents in nucleated patches from large layer 5 cortical pyramidal neurons of the rat.
Topics: 4-Aminopyridine; Animals; Cadmium; Electric Stimulation; In Vitro Techniques; Ion Channel Gating; Kinetics; Membrane Potentials; Models, Chemical; Neocortex; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Rats; Rats, Wistar; Tetraethylammonium; Tetrodotoxin | 2000 |
Voltage-gated K+ channels in layer 5 neocortical pyramidal neurones from young rats: subtypes and gradients.
Topics: 4-Aminopyridine; Age Factors; Animals; Dendrites; Electric Stimulation; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channels; Pyramidal Cells; Rats; Rats, Wistar; Somatosensory Cortex; Tetraethylammonium; Tetrodotoxin | 2000 |
Effects of voltage-gated ion channel modulators on rat prostatic cancer cell proliferation: comparison of strongly and weakly metastatic cell lines.
Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Cell Division; Charybdotoxin; Dose-Response Relationship, Drug; Formazans; Ion Channel Gating; Male; Neurotoxins; Patch-Clamp Techniques; Potassium Channels; Prostatic Neoplasms; Rats; Scorpion Venoms; Sodium Channels; Tetrazolium Salts; Tetrodotoxin; Tumor Cells, Cultured; Verapamil; Veratridine | 2000 |
A new class of neurotoxin from wasp venom slows inactivation of sodium current.
Topics: 4-Aminopyridine; Action Potentials; Amino Acid Sequence; Animals; Animals, Newborn; Cells, Cultured; Cnidarian Venoms; Hippocampus; Insect Proteins; Ion Channel Gating; Nephropidae; Neurons; Neurotoxins; Presynaptic Terminals; Rats; Rats, Wistar; Scorpion Venoms; Sodium; Sodium Channels; Structure-Activity Relationship; Tetrodotoxin; Trigeminal Ganglion; Wasp Venoms | 2000 |
Immunocytochemical and physiological characterization of a population of cultured human neural precursors.
Topics: 4-Aminopyridine; Action Potentials; Antimetabolites; Biomarkers; Bromodeoxyuridine; Calcium; Cell Differentiation; Cell Division; Cell Lineage; Cells, Cultured; Fetus; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Intermediate Filament Proteins; Ion Channel Gating; Kinetics; Microtubule-Associated Proteins; Nerve Tissue Proteins; Nestin; Neural Cell Adhesion Molecules; Neurofilament Proteins; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Sodium Channels; Stem Cells; Tetrodotoxin; Tubulin | 2000 |
Electrophysiological properties of lumbosacral preganglionic neurons in the neonatal rat spinal cord.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Axonal Transport; Electric Stimulation; Fluorescent Dyes; Lumbosacral Region; Membrane Potentials; Neurons; Parasympathetic Nervous System; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reaction Time; Spinal Cord; Tetrodotoxin | 2000 |
Hyperpolarization-activated, mixed-cation current (I(h)) in octopus cells of the mammalian cochlear nucleus.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Barium; Bucladesine; Cadmium; Cardiotonic Agents; Cations; Cesium; Cochlear Nucleus; Guanosine Triphosphate; Kinetics; Membrane Potentials; Mice; Mice, Inbred ICR; Neurons; Patch-Clamp Techniques; Pyrimidines; Tetraethylammonium; Tetrodotoxin | 2000 |
The role of intrinsic and agonist-activated conductances in determining the firing patterns of preoptic area neurons in the guinea pig.
Topics: 4-Aminopyridine; Action Potentials; Animals; Baclofen; Barium Compounds; Cesium; Chlorides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; Female; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Neurons; Nickel; Ovariectomy; Patch-Clamp Techniques; Potassium Channels; Preoptic Area; Pyrimidines; Reaction Time; Tetrodotoxin | 2000 |
The chemotherapeutic oxaliplatin alters voltage-gated Na(+) channel kinetics on rat sensory neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Carbamazepine; Electric Stimulation; Ganglia, Spinal; Hippocampus; In Vitro Techniques; Kinetics; Membrane Potentials; Nerve Fibers; Neurons, Afferent; Organoplatinum Compounds; Oxaliplatin; Potassium Channels; Rats; Sodium Channels; Sural Nerve; Tetraethylammonium; Tetrodotoxin; Time Factors; Vagus Nerve | 2000 |
Excitable properties in astrocytes derived from human embryonic CNS stem cells.
Topics: 4-Aminopyridine; Action Potentials; Astrocytes; Cell Count; Cell Size; Cells, Cultured; Central Nervous System; Glial Fibrillary Acidic Protein; Humans; Ion Channels; Microtubule-Associated Proteins; Potassium Channels; Sodium Channels; Stem Cells; Tetrodotoxin | 2000 |
Voltage-dependent Na(+) currents in mammalian retinal cone bipolar cells.
Topics: 4-Aminopyridine; Animals; Bicuculline; Calcium; Cobalt; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Mammals; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Receptors, GABA; Retina; Retinal Cone Photoreceptor Cells; Sodium; Sodium Channels; Tetrodotoxin; Visual Pathways | 2000 |
Dendritic coincidence detection of EPSPs and action potentials.
Topics: 4-Aminopyridine; Action Potentials; Animals; Biological Clocks; Dendrites; Excitatory Postsynaptic Potentials; In Vitro Techniques; Models, Neurological; Neuronal Plasticity; Potassium Channel Blockers; Potassium Channels; Pyramidal Cells; Rats; Rats, Wistar; Reaction Time; Sodium Channel Blockers; Sodium Channels; Somatosensory Cortex; Tetrodotoxin | 2001 |
Direct depolarization and antidromic action potentials transiently suppress dendritic IPSPs in hippocampal CA1 pyramidal cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Carbachol; Cholinergic Agonists; Dendrites; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrodotoxin | 2001 |
Theta-frequency bursting and resonance in cerebellar granule cells: experimental evidence and modeling of a slow k+-dependent mechanism.
Topics: 4-Aminopyridine; Animals; Biological Clocks; Calcium; Cerebellum; Cytoplasmic Granules; Electric Stimulation; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; Models, Neurological; Neurons; Nickel; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Sodium; Tetraethylammonium; Tetrodotoxin; Theta Rhythm | 2001 |
Firing properties of identified superior laryngeal neurons in the nucleus ambiguus in the rat.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Excitatory Amino Acid Antagonists; Laryngeal Nerves; Rats; Synaptic Transmission; Tetrodotoxin | 2001 |
Distinct K currents result in physiologically distinct cell types in the inferior colliculus of the rat.
Topics: 4-Aminopyridine; Action Potentials; Adaptation, Physiological; Animals; Apamin; Calcium; Charybdotoxin; Electric Stimulation; In Vitro Techniques; Inferior Colliculi; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Long-Evans; Tetraethylammonium; Tetrodotoxin | 2001 |
Characterization of a high-voltage-activated IA current with a role in spike timing and locomotor pattern generation.
Topics: 4-Aminopyridine; Action Potentials; Animals; Catechols; Cells, Cultured; Electric Conductivity; Excitatory Amino Acid Agonists; In Vitro Techniques; Lampreys; Motor Activity; Motor Neurons; N-Methylaspartate; Nerve Net; Potassium Channel Blockers; Potassium Channels; Sodium Channels; Spinal Cord; Swimming; Tetraethylammonium; Tetrodotoxin | 2001 |
Ion channels associated with the ectopic discharges generated after segmental spinal nerve injury in the rat.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cadmium; Calcium Channel Blockers; Calcium Channels; Cobalt; Ion Channels; Ion Transport; Lidocaine; Ligation; Male; Nerve Fibers; Nerve Tissue Proteins; Neurons, Afferent; Neurotoxins; Potassium Channels; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channel Blockers; Spinal Nerves; Synaptic Transmission; Tetrodotoxin | 2001 |
Synchronized Ca2+ signals mediated by Ca2+ action potentials in the hippocampal neuron network in vitro.
Topics: 4-Aminopyridine; Action Potentials; Animals; Biological Clocks; Calcium; Calcium Channels; Calcium Signaling; Cells, Cultured; Cesium; Hippocampus; Nerve Net; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Synaptic Transmission; Tetrodotoxin | 2001 |
Membrane resonance and subthreshold membrane oscillations in mesencephalic V neurons: participants in burst generation.
Topics: 4-Aminopyridine; Aging; Animals; Biological Clocks; Cell Membrane; In Vitro Techniques; Membrane Potentials; Mesencephalon; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Signal Processing, Computer-Assisted; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin | 2001 |
Skin surface electric potential induced by ion-flux through epidermal cell layers.
Topics: 4-Aminopyridine; Adenosine Triphosphatases; Animals; Calcium Channel Blockers; Chelating Agents; Corticotropin-Releasing Hormone; Enzyme Inhibitors; Galvanic Skin Response; In Vitro Techniques; Ion Transport; Ionophores; Male; Membrane Potentials; Mice; Mice, Hairless; Mitochondria; Potassium Channel Blockers; Skin; Skin Physiological Phenomena; Sodium Azide; Sodium Channel Blockers; Substance P; Tetrodotoxin | 2001 |
Long-term recordings of networks of immortalized GnRH neurons reveal episodic patterns of electrical activity.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cell Line, Transformed; Electrophysiology; Gonadotropin-Releasing Hormone; Microelectrodes; Neurons; Periodicity; Potassium Channel Blockers; Potassium Channels; Sodium Channel Blockers; Sodium Channels; Software; Tetrodotoxin | 2001 |
Membrane properties of principal neurons of the lateral superior olive.
Topics: 4-Aminopyridine; Action Potentials; Animals; Barium; Cesium; Electric Conductivity; Neurons; Nickel; Olivary Nucleus; Patch-Clamp Techniques; Potassium; Rats; Rats, Long-Evans; Sodium; Tetrodotoxin | 2001 |
Compartmental models of rat cerebellar Purkinje cells based on simultaneous somatic and dendritic patch-clamp recordings.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cadmium Chloride; Cations; Cell Compartmentation; Cell Size; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Purkinje Cells; Pyridazines; Rats; Rats, Wistar; Tetraethylammonium; Tetrodotoxin | 2001 |
Highly 4-aminopyridine sensitive delayed rectifier current modulates the excitability of guinea pig cerebellar Purkinje cells.
Topics: 4-Aminopyridine; Animals; Calcium Channels; Cerebellum; Delayed Rectifier Potassium Channels; Dendrites; Guinea Pigs; In Vitro Techniques; Male; Potassium Channels; Potassium Channels, Voltage-Gated; Purkinje Cells; Sodium Channels; Tetrodotoxin | 2001 |
GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons.
Topics: 4-Aminopyridine; Anesthetics, Local; Animals; Cells, Cultured; Culture Media, Serum-Free; Dopamine; Dose-Response Relationship, Drug; Fluorescent Dyes; Glial Cell Line-Derived Neurotrophic Factor; In Vitro Techniques; Male; Membrane Potentials; Mesencephalon; Mitogen-Activated Protein Kinases; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetrodotoxin | 2001 |
Voltage-gated sodium channels shape subthreshold EPSPs in layer 5 pyramidal neurons from rat prefrontal cortex.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Cadmium; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Ion Channel Gating; Lidocaine; Male; Nickel; Organ Culture Techniques; Potassium Channel Blockers; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Channels; Synapses; Tetraethylammonium; Tetrodotoxin | 2001 |
Control of the propagation of dendritic low-threshold Ca(2+) spikes in Purkinje cells from rat cerebellar slice cultures.
Topics: 4-Aminopyridine; Action Potentials; Agatoxins; Anesthetics, Local; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cerebellum; Chelating Agents; Dendrites; Egtazic Acid; Evoked Potentials; Organ Culture Techniques; Potassium Channel Blockers; Purkinje Cells; Rats; Rats, Wistar; Spider Venoms; Tetraethylammonium; Tetrodotoxin | 2002 |
Patch-clamp recordings from white matter glia in thin longitudinal slices of adult rat spinal cord.
Topics: 4-Aminopyridine; Action Potentials; Animals; Astrocytes; Axons; Female; Oligodendroglia; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Spinal Cord; Tetraethylammonium; Tetrodotoxin | 2002 |
Ciguatoxin-induced oscillations in membrane potential and action potential firing in rat parasympathetic neurons.
Topics: 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Action Potentials; Animals; Animals, Newborn; Biological Clocks; Cell Membrane; Cells, Cultured; Ciguatoxins; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Parasympathetic; Marine Toxins; Metals; Neurons; Ouabain; Oxocins; Rats; Sodium Channels; Tetraethylammonium; Tetrodotoxin | 2002 |
Micromolar lidocaine selectively blocks propagating ectopic impulses at a distance from their site of origin.
Topics: 4-Aminopyridine; Action Potentials; Anesthetics, Local; Animals; Cnidarian Venoms; Electric Stimulation; Lidocaine; Potassium Channel Blockers; Rana catesbeiana; Rana pipiens; Sciatica; Tetrodotoxin | 2002 |
Presynaptic factors in the regulation of DSI expression in hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Male; Membrane Potentials; omega-Conotoxin GVIA; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Signal Transduction; Tetraethylammonium; Tetrodotoxin | 2002 |
Contribution of the K(Ca) channel to membrane potential and O2 sensitivity is decreased in an ovine PPHN model.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Disease Models, Animal; Female; Gestational Age; Hypertension, Pulmonary; Membrane Potentials; Muscle, Smooth, Vascular; Peptides; Potassium Channels, Calcium-Activated; Pregnancy; Pulmonary Artery; Pulmonary Circulation; Sheep; Tetrodotoxin; Vasodilation | 2002 |
Raphé grafts and 3,4-diaminopyridine-evoked overflow of serotonin in the rat hippocampus after 5,7-dihydroxytryptamine lesions: evidence for 5-HT1A autoreceptors.
Topics: 4-Aminopyridine; 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amifampridine; Animals; Autoreceptors; Brain Tissue Transplantation; Calcium; Calcium Signaling; Cells, Cultured; Denervation; Fetus; Hippocampus; Male; Neurons; Neurotoxins; Organ Culture Techniques; Potassium Channel Blockers; Raphe Nuclei; Rats; Rats, Long-Evans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Tetrodotoxin | 2002 |
Membrane properties related to the firing behavior of zebrafish motoneurons.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Anesthetics, Local; Animals; Calcium Channels; Cobalt; Motor Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Sodium Channels; Swimming; Tetraethylammonium; Tetrodotoxin; Zebrafish | 2003 |
Normalization of Ca2+ signals by small oblique dendrites of CA1 pyramidal neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Dendrites; Electric Stimulation; Fluorescent Dyes; Hippocampus; In Vitro Techniques; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin | 2003 |
Regulation of backpropagating action potentials in mitral cell lateral dendrites by A-type potassium currents.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Action Potentials; Animals; Axons; Calcium Signaling; Dendrites; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Olfactory Bulb; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 2003 |
A toxic fraction from scolopendra venom increases the basal release of neurotransmitters in the ventral ganglia of crustaceans.
Topics: 4-Aminopyridine; Animals; Arthropod Venoms; Calcium; Crustacea; Electrophoresis, Polyacrylamide Gel; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Neurotransmitter Agents; Tetrodotoxin | 2003 |
Reduction of voltage-operated potassium currents by levetiracetam: a novel antiepileptic mechanism of action?
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Levetiracetam; Neural Conduction; Neurons; Patch-Clamp Techniques; Piracetam; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2003 |
Transforming growth factor-alpha changes firing properties of developing neocortical GABAergic neurons by down-regulation of voltage-gated potassium currents.
Topics: 4-Aminopyridine; Action Potentials; Anesthetics, Local; Animals; Cadmium; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Embryo, Mammalian; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Neocortex; Neurons; Organ Culture Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyramidal Cells; Rats; Reaction Time; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Shab Potassium Channels; Tetrodotoxin; Transforming Growth Factor alpha | 2003 |
Synaptic and non-synaptic mechanisms of amygdala recruitment into temporolimbic epileptiform activities.
Topics: 4-Aminopyridine; Action Potentials; Amygdala; Anesthetics, Local; Animals; Anti-Ulcer Agents; Bicuculline; Carbenoxolone; Dissection; Electric Stimulation; Entorhinal Cortex; Epilepsy; Evoked Potentials; Extracellular Space; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Neurons; Phosphinic Acids; Potassium; Propanolamines; Rats; Rats, Wistar; Reaction Time; Synapses; Tetrodotoxin; Time Factors | 2003 |
Characterization of the participation of sodium channels on the rise in Na+ induced by 4-aminopyridine (4-AP) in synaptosomes.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channel Blockers; Corpus Striatum; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Male; Neurotransmitter Agents; Osmolar Concentration; Ouabain; Potassium; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Sodium Channels; Synaptosomes; Tetrodotoxin; Veratridine | 2004 |
PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Apoptosis; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Central Nervous System Depressants; Cerebellum; Cholera Toxin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Delayed Rectifier Potassium Channels; Drug Interactions; Electric Conductivity; Enzyme Inhibitors; Ethanol; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Isoquinolines; Membrane Potentials; Models, Neurological; Neural Inhibition; Neurons; Neuropeptides; Patch-Clamp Techniques; Peptide Fragments; Pertussis Toxin; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Signal Transduction; Sulfonamides; Tetraethylammonium; Tetrodotoxin; Thionucleotides; Time Factors; Vasoactive Intestinal Peptide | 2004 |
Orexigen-sensitive NPY/AgRP pacemaker neurons in the hypothalamic arcuate nucleus.
Topics: 4-Aminopyridine; Agouti-Related Protein; Anesthetics, Local; Animals; Arcuate Nucleus of Hypothalamus; Carrier Proteins; Drug Interactions; Ghrelin; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Leptin; Male; Membrane Potentials; Neurons; Neuropeptide Y; Neuropeptides; Nickel; Orexin Receptors; Orexins; Patch-Clamp Techniques; Peptide Hormones; Potassium Channel Blockers; Proteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leptin; Receptors, Neuropeptide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrodotoxin | 2004 |
Input resistance is voltage dependent due to activation of Ih channels in rat CA1 pyramidal cells.
Topics: 4-Aminopyridine; Acetates; Amines; Animals; Animals, Newborn; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Radiation; Electric Impedance; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channel Gating; Ion Channels; Membrane Potentials; Nickel; Patch-Clamp Techniques; Potassium Channel Blockers; Pyramidal Cells; Pyrimidines; Rats; Rats, Wistar; Tetrodotoxin | 2004 |
Substance P induces inward current and regulates pacemaker currents through tachykinin NK1 receptor in cultured interstitial cells of Cajal of murine small intestine.
Topics: 4-Aminopyridine; Action Potentials; Alkaloids; Animals; Benzophenanthridines; Calcium; Cations, Divalent; Cells, Cultured; Electrophysiology; Enteric Nervous System; Female; Glyburide; Intestine, Small; Ion Channels; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Nifedipine; Phenanthridines; Receptors, Neurokinin-1; Sinoatrial Node; Sodium; Substance P; Tachykinins; Tetraethylammonium; Tetrodotoxin | 2004 |
Phasic stimuli evoke precisely timed spikes in intermittently discharging mitral cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Differential Threshold; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; Neurons; Olfactory Bulb; Oscillometry; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Reaction Time; Reproducibility of Results; Sodium Channels; Tetrodotoxin | 2004 |
Sodium-activated potassium conductance participates in the depolarizing afterpotential following a single action potential in rat hippocampal CA1 pyramidal cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Extracellular Space; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Lithium; Male; Neural Conduction; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2004 |
Dopamine modulates excitability of basolateral amygdala neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amygdala; Anesthetics, Local; Animals; Animals, Newborn; Benzazepines; Dopamine; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; Elapid Venoms; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Neurons; Neurons, Afferent; Patch-Clamp Techniques; Potassium Channel Blockers; Quinpirole; Rats; Staining and Labeling; Sulpiride; Synaptic Transmission; Tetrodotoxin | 2005 |
Stressor-related impairment of synaptic transmission in hippocampal slices from alpha-synuclein knockout mice.
Topics: 4-Aminopyridine; Adenosine; alpha-Synuclein; Analgesics; Anesthetics, Local; Animals; Blotting, Western; Drug Interactions; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Potassium Channel Blockers; Synaptic Transmission; Synucleins; Tetrodotoxin; Theophylline; Time Factors | 2004 |
Orexins cause depolarization via nonselective cationic and K+ channels in isolated locus coeruleus neurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Intracellular Signaling Peptides and Proteins; Ion Channels; Locus Coeruleus; Membrane Potentials; Neurons; Neuropeptides; Orexins; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2005 |
Properties of synaptically evoked astrocyte calcium signal reveal synaptic information processing by astrocytes.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Aniline Compounds; Animals; Animals, Newborn; Astrocytes; Atropine; Calcium; Calcium Signaling; Cell Communication; Diagnostic Imaging; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glutamic Acid; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Muscarinic Antagonists; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Tetrodotoxin; Xanthenes | 2005 |
Characterization of ionic currents in human mesenchymal stem cells from bone marrow.
Topics: 4-Aminopyridine; Bone Marrow Cells; Calcium Channels, L-Type; Cell Differentiation; Cells, Cultured; Ether-A-Go-Go Potassium Channels; Gene Expression; Humans; Ion Channels; Kv1.4 Potassium Channel; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Mesenchymal Stem Cells; NAV1.7 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Nifedipine; Patch-Clamp Techniques; Peptides; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; RNA, Messenger; Shal Potassium Channels; Sodium Channels; Tetrodotoxin | 2005 |
Biophysical characterization of whole-cell currents in O2-sensitive neurons from the rat glossopharyngeal nerve.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Cadmium; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Glossopharyngeal Nerve; Hypoxia; Immunohistochemistry; Ion Channels; Membrane Potentials; Neurons; Nickel; Oxygen; Patch-Clamp Techniques; Potassium Channel Blockers; Pyridinium Compounds; Rats; Rats, Wistar; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2005 |
Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Calcium; Calcium Channels; Calcium Signaling; Dose-Response Relationship, Drug; Male; Neostriatum; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Sodium Channels; Synapses; Synaptic Membranes; Synaptic Transmission; Synaptosomes; Tetrodotoxin; Up-Regulation; Vinca Alkaloids | 2005 |
Sex differences in the cannabinoid modulation of an A-type K+ current in neurons of the mammalian hypothalamus.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Arcuate Nucleus of Hypothalamus; Benzoxazines; beta-Endorphin; Calcium Channel Blockers; Cannabinoids; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Immunohistochemistry; In Vitro Techniques; Male; Morpholines; Naphthalenes; Neurons; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyrazoles; Sex Characteristics; Tetrodotoxin | 2005 |
Dopamine modulation of two delayed rectifier potassium currents in a small neural network.
Topics: 4-Aminopyridine; Animals; Cadmium Chloride; Delayed Rectifier Potassium Channels; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Invertebrate; In Vitro Techniques; Membrane Potentials; Nerve Net; Neural Conduction; Neurons; Palinuridae; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Quinidine; Tetraethylammonium; Tetrodotoxin | 2005 |
Effect of 4-aminopyridine (4-AP) on the spontaneous activity and neuromuscular junction in the rat colon.
Topics: 4-Aminopyridine; Animals; Colon; Male; Neuromuscular Junction; Nitroarginine; Potassium Channels; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrodotoxin | 2005 |
Ca2+-activated K+-current density is correlated with soma size in rat vestibular-afferent neurons in culture.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Apamin; Calcium; Cell Size; Cells, Cultured; Charybdotoxin; Clotrimazole; Dose-Response Relationship, Radiation; Drug Interactions; Electric Capacitance; Electric Stimulation; Membrane Potentials; Neurons, Afferent; Neurotoxins; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Tetraethylammonium; Tetrodotoxin; Vestibule, Labyrinth | 2005 |
Inhibition of Na+ channel currents in rat myoblasts by 4-aminopyridine.
Topics: 4-Aminopyridine; Animals; Dose-Response Relationship, Drug; Kinetics; Membrane Potentials; Myoblasts; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin | 2005 |
GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basic Helix-Loop-Helix Transcription Factors; Bicuculline; Bromodeoxyuridine; Calbindins; Calcium; Cell Count; Cell Differentiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Green Fluorescent Proteins; Hippocampus; History, Ancient; Immunohistochemistry; In Vitro Techniques; Intermediate Filament Proteins; Ki-67 Antigen; Membrane Potentials; Mice; Mice, Transgenic; Microscopy, Immunoelectron; N-Methylaspartate; Nerve Tissue Proteins; Nestin; Neural Cell Adhesion Molecule L1; Neurons; Nickel; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Potassium Channel Blockers; S100 Calcium Binding Protein G; Sialic Acids; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Stem Cells; Tetrodotoxin; Vesicular Inhibitory Amino Acid Transport Proteins | 2005 |
Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Calcium; Diagnostic Imaging; Drug Interactions; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Microscopy, Confocal; Neurons; Neurotoxins; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetanus Toxin; Tetrodotoxin; Time Factors | 2005 |
Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release.
Topics: 4-Aminopyridine; Anesthetics, Inhalation; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Enflurane; gamma-Aminobutyric Acid; Glutamic Acid; Halothane; In Vitro Techniques; Isoflurane; Male; Nerve Endings; Neurotransmitter Agents; Potassium Channel Blockers; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 2006 |
Depolarization-induced release of ethanolamine from brain synaptic preparations in vitro.
Topics: 4-Aminopyridine; Anesthetics, Local; Animals; Brain; Ethanolamine; In Vitro Techniques; Male; Mice; Neuromuscular Depolarizing Agents; Neurons; Synaptosomes; Tetrodotoxin; Veratridine | 2005 |
Transient voltage-dependent potassium currents are reduced in NTS neurons isolated from renal wrap hypertensive rats.
Topics: 4-Aminopyridine; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Hypertension, Renal; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channels; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Reaction Time; Sodium Channel Blockers; Solitary Nucleus; Tetraethylammonium; Tetrodotoxin; Time Factors | 2005 |
The Edinger-Westphal nucleus of the juvenile rat contains transient- and repetitive-firing neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Brain Stem; Corticotropin-Releasing Hormone; Dose-Response Relationship, Radiation; Electric Stimulation; Female; Ganglia, Parasympathetic; Immunohistochemistry; In Vitro Techniques; Lysine; Male; Neurons; Nickel; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium Channel Blockers; Tetrodotoxin; Urocortins | 2006 |
Involvement of persistent Na+ current in spike initiation in primary sensory neurons of the rat mesencephalic trigeminal nucleus.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Lidocaine; Neurons, Afferent; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Riluzole; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Trigeminal Nuclei | 2007 |
Roles of volume-sensitive chloride channel in excitotoxic neuronal injury.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Apoptosis; Benzothiadiazines; Bicuculline; Bumetanide; Cell Size; Cells, Cultured; Cerebral Cortex; Chlorides; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glycolates; Ion Channels; Mice; Mice, Inbred C57BL; N-Methylaspartate; Necrosis; Neurons; Neurotoxins; Nitrobenzoates; Patch-Clamp Techniques; Phloretin; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Quinine; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Sodium Chloride Symporters; Somatosensory Cortex; Tetrodotoxin | 2007 |
Somatostatinergic modulation of firing pattern and calcium-activated potassium currents in medium spiny neostriatal neurons.
Topics: 4-Aminopyridine; Action Potentials; Anesthetics, Local; Animals; Apamin; Calcitonin; Corpus Striatum; Dendritic Spines; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Gene Expression; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Peptide Fragments; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Receptors, Somatostatin; Somatostatin; Tetrodotoxin | 2007 |
Effects of phorbol-12,13-dibuterate on sodium currents and potassium currents in rat trigeminal ganglion neurons.
Topics: 4-Aminopyridine; Animals; Cells, Cultured; Neurons; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Sodium Channel Agonists; Sodium Channel Blockers; Sodium Channels; Tetraethylammonium; Tetrodotoxin; Trigeminal Ganglion | 2007 |
The functional difference between transient and sustained K+ currents on the action potentials in tetrodotoxin-resistant adult rat trigeminal ganglion neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cells, Cultured; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Tetraethylammonium; Tetrodotoxin; Trigeminal Ganglion | 2007 |
Differential expression of intrinsic membrane currents in defined cell types of the anterolateral bed nucleus of the stria terminalis.
Topics: 4-Aminopyridine; Aging; Animals; Benzylamines; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agents; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channel Blockers; Quinoxalines; Rats; Septal Nuclei; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2007 |
Role of K(+) channels in the regulation of electrical spontaneous activity of the mouse small intestine.
Topics: 4-Aminopyridine; Animals; Apamin; Charybdotoxin; Electrophysiology; Female; Ileum; Male; Mice; Mice, Inbred BALB C; Nifedipine; Peptides; Phenylephrine; Potassium Channels; Potassium Channels, Calcium-Activated; Tetrodotoxin | 2007 |
The effect of zinc on glycinergic inhibitory postsynaptic currents in rat spinal dorsal horn neurons.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Drug Interactions; Glycine; Glycine Agents; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neural Inhibition; Platelet Aggregation Inhibitors; Posterior Horn Cells; Potassium Channel Blockers; Pyridoxal Phosphate; Rats; Rats, Wistar; Spinal Cord; Strychnine; Tetrodotoxin; Trace Elements; Zinc | 2007 |
Effects of ralfinamide, a Na+ channel blocker, on firing properties of nociceptive dorsal root ganglion neurons of adult rats.
Topics: 4-Aminopyridine; Action Potentials; Animals; Capsaicin; Drug Resistance; Electric Stimulation; Electrophysiology; Fluorobenzenes; Ganglia, Spinal; Male; Neurons; Nociceptors; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sodium Channel Blockers; Substance P; Tetrodotoxin | 2007 |
Involvement of voltage-gated K+ and Na+ channels in gastric epithelial cell migration.
Topics: 4-Aminopyridine; Animals; Barium; Cell Line; Cell Movement; Epidermal Growth Factor; Epithelial Cells; Gastric Mucosa; Gene Expression Regulation; Ion Channel Gating; Nifedipine; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Rats; RNA, Messenger; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin | 2008 |
Currents contributing to decision making in neurons B31/B32 of Aplysia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Aplysia; Behavior, Animal; Computer Simulation; Decision Making; Dose-Response Relationship, Radiation; Drug Interactions; Electric Conductivity; Electric Stimulation; Locomotion; Models, Neurological; Motor Neurons; Muscarinic Agonists; Oxotremorine; Patch-Clamp Techniques; Potassium Channel Blockers; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin; Time Factors | 2008 |
Subthreshold sodium current underlies essential functional specializations at primary auditory afferents.
Topics: 4-Aminopyridine; Acoustic Stimulation; Animals; Computer Simulation; Electric Stimulation; Electrophysiology; Goldfish; Hearing; Membrane Potentials; Neurons, Afferent; Potassium Channel Blockers; Potassium Channels; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Vestibulocochlear Nerve | 2008 |
Iberiotoxin-sensitive large conductance Ca2+ -dependent K+ (BK) channels regulate the spike configuration in the burst firing of cerebellar Purkinje neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Apamin; Cerebellum; Electric Stimulation; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Male; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Purkinje Cells; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2008 |
Conductances mediating intrinsic theta-frequency membrane potential oscillations in layer II parasubicular neurons.
Topics: 4-Aminopyridine; Animals; Bicuculline; Biological Clocks; Calcium Channel Blockers; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channel Blockers; Propanolamines; Pyrimidines; Rats; Rats, Long-Evans; Sodium Channel Blockers; Tetrodotoxin; Theta Rhythm | 2008 |
Quantitative assessment of the distributions of membrane conductances involved in action potential backpropagation along basal dendrites.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Biophysical Phenomena; Calcium; Dendrites; Electric Conductivity; Electric Stimulation; In Vitro Techniques; Ion Channel Gating; Models, Neurological; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Signal Processing, Computer-Assisted; Sodium Channel Blockers; Styrenes; Tetrodotoxin | 2009 |
Electrophysiological properties of octopus neurons of the cat cochlear nucleus: an in vitro study.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cardiovascular Agents; Cats; Cochlear Nucleus; Dendrites; Elapid Venoms; Evoked Potentials; Ion Channels; Mice; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Pyrimidines; Sodium Channel Blockers; Stellate Ganglion; Tetrodotoxin | 2009 |
Brain-derived neurotrophic factor and electrophysiological properties of voltage-gated ion channels during neuronal stem cell development.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Biophysical Phenomena; Biophysics; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cells, Cultured; Electric Stimulation; Embryo, Mammalian; Embryonic Stem Cells; Glial Fibrillary Acidic Protein; Hippocampus; Humans; Ion Channel Gating; Ion Channels; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin; Tubulin | 2009 |
Membrane current-based mechanisms for excitability transitions in neurons of the rat mesencephalic trigeminal nuclei.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Cadmium Compounds; Calcium Channels; Cell Membrane; Female; In Vitro Techniques; Male; Mesencephalon; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Tetraethylammonium; Tetrodotoxin; Trigeminal Nuclei | 2009 |
Reduction of repolarization reserve unmasks the proarrhythmic role of endogenous late Na(+) current in the heart.
Topics: 4-Aminopyridine; Acetanilides; Action Potentials; Animals; Anti-Arrhythmia Agents; Barium Compounds; Cell Line; Chlorides; Enzyme Inhibitors; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Heart Conduction System; Humans; Kidney; Patch-Clamp Techniques; Piperazines; Piperidines; Potassium Channel Blockers; Pyridines; Rabbits; Ranolazine; Sodium; Sodium Channel Blockers; Sodium Channels; Tachycardia, Ventricular; Tetrodotoxin; Torsades de Pointes | 2009 |
Neocortical disynaptic inhibition requires somatodendritic integration in interneurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Biophysics; Channelrhodopsins; Dendrites; Electric Stimulation; Electroporation; Embryo, Mammalian; gamma-Aminobutyric Acid; Glutamic Acid; Green Fluorescent Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Mice; Mice, Inbred ICR; Mice, Transgenic; Neocortex; Neural Inhibition; Parvalbumins; Patch-Clamp Techniques; Photic Stimulation; Potassium Channel Blockers; Rats; Rats, Wistar; Reaction Time; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2009 |
Development of K(+) and Na(+) conductances in rodent postnatal semicircular canal type I hair cells.
Topics: 4-Aminopyridine; Aging; Animals; Data Interpretation, Statistical; Electrophysiology; Gerbillinae; Hair Cells, Auditory, Inner; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Semicircular Canals; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Vestibule, Labyrinth | 2010 |
Differences in Na+ conductance density and Na+ channel functional properties between dopamine and GABA neurons of the rat substantia nigra.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Neural Conduction; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium Channel Blockers; Sodium Channels; Substantia Nigra; Tetraethylammonium; Tetrodotoxin | 2010 |
Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS.
Topics: 4-Aminopyridine; Aniline Compounds; Animals; Central Nervous System; Dose-Response Relationship, Drug; Drug Interactions; Furans; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Male; Potassium Channel Blockers; Presynaptic Terminals; Protein Subunits; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Veratridine | 2010 |
Characterization of voltage-gated K+ currents contributing to subthreshold membrane potential oscillations in hippocampal CA1 interneurons.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Bicuculline; Biological Clocks; Biophysical Phenomena; CA1 Region, Hippocampal; Elapid Venoms; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Interneurons; Ion Channel Gating; Male; Membrane Potentials; Models, Neurological; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2010 |
Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Calcium; Carbamazepine; Drug Interactions; Epilepsy; Fructose; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Lamotrigine; Male; Nerve Endings; Oxcarbazepine; Phenytoin; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetrodotoxin; Topiramate; Triazines; Tritium; Vinca Alkaloids | 2011 |
State-dependent, bidirectional modulation of neural network activity by endocannabinoids.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Benzothiadiazines; Brain; Cannabinoid Receptor Modulators; Cells, Cultured; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Mice; Mice, Transgenic; Nerve Net; Neural Inhibition; Neurons; Organophosphorus Compounds; Picrotoxin; Piperidines; Potassium Channel Blockers; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sodium Channel Blockers; Tetrodotoxin; Valine | 2011 |
Effects of axonal topology on the somatic modulation of synaptic outputs.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Axons; Biophysics; Calcium; Computer Simulation; Egtazic Acid; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Hippocampus; Male; Models, Neurological; Nerve Net; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Channel Blockers; Presynaptic Terminals; Rats; Rats, Wistar; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2012 |
Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Bicuculline; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Corpus Striatum; CREB-Binding Protein; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agents; Female; GABA-A Receptor Antagonists; Glutamate Decarboxylase; Glycine Agents; Luminescent Proteins; Microfluidic Analytical Techniques; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nifedipine; Patch-Clamp Techniques; Potassium Channel Blockers; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium Channel Blockers; Strychnine; Synapses; Tetrodotoxin; Transfection; Vesicular Glutamate Transport Protein 1 | 2012 |
Spike-timing precision and neuronal synchrony are enhanced by an interaction between synaptic inhibition and membrane oscillations in the amygdala.
Topics: 4-Aminopyridine; Action Potentials; Adenylyl Cyclases; Amygdala; Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dopamine; Inhibitory Postsynaptic Potentials; Macaca mulatta; Male; Membrane Potentials; Neurons; Nickel; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetraethylammonium; Tetrodotoxin | 2012 |
Rapid homeostatic plasticity of intrinsic excitability in a central pattern generator network stabilizes functional neural network output.
Topics: 4-Aminopyridine; Action Potentials; Analysis of Variance; Animals; Brachyura; Chelating Agents; Cyclosporine; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Female; Ganglia, Invertebrate; Homeostasis; Male; Motor Neurons; Nerve Net; Neuronal Plasticity; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; RNA, Messenger; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2012 |
Focal cerebral ischemia induces the neurogenic potential of mouse Dach1-expressing cells in the dorsal part of the lateral ventricles.
Topics: 4-Aminopyridine; Adult Stem Cells; Animals; Cell Count; Cell Differentiation; Disease Models, Animal; Eye Proteins; Green Fluorescent Proteins; In Vitro Techniques; Infarction, Middle Cerebral Artery; Lateral Ventricles; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Degeneration; Nerve Tissue Proteins; Neurogenesis; Neurons; Patch-Clamp Techniques; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2013 |
Increase in neuroexcitability of unmyelinated C-type vagal ganglion neurons during initial postnatal development of visceral afferent reflex functions.
Topics: 4-Aminopyridine; Action Potentials; Age Factors; Animals; Animals, Newborn; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neurons; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Reflex; Sodium Channel Blockers; Tetrodotoxin; Vagus Nerve; Visceral Afferents | 2013 |
Heterogeneous intrinsic excitability of murine spiral ganglion neurons is determined by Kv1 and HCN channels.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Biophysical Phenomena; Biophysics; Cadmium Chloride; Elapid Venoms; Electric Stimulation; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Neurotoxins; Patch-Clamp Techniques; Potassium Channel Blockers; Shaker Superfamily of Potassium Channels; Spiral Ganglion; Tetrodotoxin | 2014 |
Optogenetic activation of cajal-retzius cells reveals their glutamatergic output and a novel feedforward circuit in the developing mouse hippocampus.
Topics: 4-Aminopyridine; Animals; Chemokine CXCL12; Excitatory Postsynaptic Potentials; Feedback, Physiological; Female; GABA-A Receptor Antagonists; GABAergic Neurons; Glutamic Acid; Hippocampus; Interneurons; Male; Mice; Mice, Inbred Strains; Optogenetics; Potassium Channel Blockers; Pyramidal Cells; Pyridazines; Reaction Time; Reelin Protein; Sodium Channel Blockers; Tetrodotoxin | 2014 |
Resonance characteristic and its ionic basis of rat mesencephalic trigeminal neurons.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Animals, Newborn; Biophysical Phenomena; Electric Stimulation; Female; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Mesencephalon; Neurons; Potassium Channel Blockers; Pyrimidines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin | 2015 |
Corelease of acetylcholine and GABA from cholinergic forebrain neurons.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Choline O-Acetyltransferase; Cholinergic Neurons; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Membrane Potentials; Mice, Transgenic; Microscopy, Confocal; Microscopy, Fluorescence, Multiphoton; Patch-Clamp Techniques; Potassium Channel Blockers; Prosencephalon; Receptors, GABA-A; Receptors, Nicotinic; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Vesicular Inhibitory Amino Acid Transport Proteins | 2015 |
VEGF attenuated increase of outward delayed-rectifier potassium currents in hippocampal neurons induced by focal ischemia via PI3-K pathway.
Topics: 4-Aminopyridine; Animals; Cerebral Infarction; Disease Models, Animal; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Infarction, Middle Cerebral Artery; Kv1.2 Potassium Channel; Male; Membrane Potentials; Neurons; Phosphatidylinositol 3-Kinases; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Channel Blockers; Tetrodotoxin; Vascular Endothelial Growth Factor A | 2015 |
Hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats.
Topics: 4-Aminopyridine; Animals; Calcium; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hesperidin; Hippocampus; Kainic Acid; Male; Membrane Potentials; Neuroprotective Agents; Neurotoxicity Syndromes; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Synaptosomes; Tetrodotoxin | 2015 |
Laminar- and Target-Specific Amygdalar Inputs in Rat Primary Gustatory Cortex.
Topics: 4-Aminopyridine; Action Potentials; Afferent Pathways; Amygdala; Animals; Channelrhodopsins; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Male; Neural Inhibition; Parvalbumins; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Sensorimotor Cortex; Sodium Channel Blockers; Taste; Tetrodotoxin | 2016 |
Inhibitory modulation of optogenetically identified neuron subtypes in the rostral solitary nucleus.
Topics: 4-Aminopyridine; Action Potentials; Animals; Channelrhodopsins; Female; Glutamate Decarboxylase; In Vitro Techniques; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Neural Inhibition; Neurons; Optogenetics; Potassium Channel Blockers; Receptors, Purinergic P2X2; Sodium Channel Blockers; Solitary Nucleus; Tetrodotoxin; Vesicular Inhibitory Amino Acid Transport Proteins | 2016 |
Neuronal activity mediated regulation of glutamate transporter GLT-1 surface diffusion in rat astrocytes in dissociated and slice cultures.
Topics: 4-Aminopyridine; Anesthetics, Local; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Embryo, Mammalian; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Neurons; Organ Culture Techniques; Potassium Channel Blockers; Rats; Rats, Transgenic; Tetrodotoxin | 2016 |
Glial Calcium Waves are Triggered by Seizure Activity and Not Essential for Initiating Ictal Onset or Neurovascular Coupling.
Topics: 4-Aminopyridine; Animals; Brain Mapping; Calcium; Calcium Signaling; Carbenoxolone; Diagnostic Imaging; Disease Models, Animal; Epilepsy; Evoked Potentials, Somatosensory; Male; Neuroglia; Neurons; Neurovascular Coupling; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Somatosensory Cortex; Tetrodotoxin | 2017 |
Atomic force microscopy investigations of fibronectin and α5β1-integrin signaling in neuroplasticity and seizure susceptibility in experimental epilepsy.
Topics: 4-Aminopyridine; Action Potentials; Animals; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Antagonists; Fibronectins; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Integrin alpha6beta1; Kynurenic Acid; Male; Mice; Mice, Inbred C57BL; Microscopy, Atomic Force; Neuronal Plasticity; Neurons; Potassium Channel Blockers; Signal Transduction; Sodium Channel Blockers; Tetrodotoxin | 2017 |
Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles.
Topics: 4-Aminopyridine; Animals; Crotalid Venoms; Dose-Response Relationship, Drug; Hindlimb; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Pain Measurement; Paralysis; Potassium Channels, Voltage-Gated; Tetrodotoxin; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels | 2018 |
Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dentate Gyrus; Female; Gabapentin; Male; Mice; Muscimol; N-Methylaspartate; Neural Stem Cells; Neurons; Phenytoin; Receptors, Purinergic P2X7; Tetrodotoxin; Valproic Acid | 2018 |
Glycinergic neurotransmission in the rostral ventrolateral medulla controls the time course of baroreflex-mediated sympathoinhibition.
Topics: 4-Aminopyridine; Animals; Baroreflex; Bicuculline; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Inhibitory Postsynaptic Potentials; Male; Medulla Oblongata; Muscimol; Neural Inhibition; Neurons; Potassium Channel Blockers; Rats, Sprague-Dawley; Strychnine; Sympathetic Nervous System; Synaptic Transmission; Tetrodotoxin | 2019 |
Spreading depression as an innate antiseizure mechanism.
Topics: 4-Aminopyridine; Animals; Bicuculline; Brain Stem; Cortical Spreading Depression; Depression; Female; Gene Knock-In Techniques; Kainic Acid; Male; Mice; Nervous System; Optogenetics; Penicillins; Potassium Channel Blockers; Seizures; Tetrodotoxin | 2021 |
Aging-associated susceptibility to stress-induced ventricular arrhythmogenesis is attenuated by tetrodotoxin.
Topics: 4-Aminopyridine; Action Potentials; Aging; Animals; Arrhythmias, Cardiac; Isoproterenol; Male; Myocytes, Cardiac; Rats; Sodium; Tetrodotoxin; Ventricular Fibrillation | 2022 |