4-aminopyridine has been researched along with riluzole in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Calò, S; Costi, MP; Ferrari, S; Gupta, S; Hannaert, V; Henrich, S; Lazzari, S; Luciani, R; Michels, PA; Morandi, F; Motiejunas, D; Nerini, E; Venturelli, A; Wade, RC | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Blanchard, JC; Böhme, GA; Gandolfo, G; Gottesmann, C; Laduron, PM; Lafforgue, J; Lazdunski, M; Stutzmann, JM | 1 |
| Bernardi, G; Mercuri, NB; Siniscalchi, A; Zona, C | 1 |
| Oja, SS; Saransaari, P | 1 |
| Cahill, CM; Coderre, TJ; Fisher, K; Lefebvre, C | 1 |
| Peña, F; Tapia, R | 1 |
| Angelo, K; Frøkjaer-Jensen, C; Grunnet, M; Jensen, BS; Jespersen, T; Klaerke, DA; Olesen, SP | 1 |
| Bae, YC; Hirai, T; Kang, Y; Maeda, Y; Saito, M; Sato, H; Toyoda, H | 1 |
| Hu, S; Liu, Y; Yang, J | 1 |
11 other study(ies) available for 4-aminopyridine and riluzole
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase.
Topics: Benzothiazoles; Central Nervous System Agents; Drug Design; Drug Synergism; Fibroblasts; Humans; Leishmania; Models, Molecular; Oxidoreductases; Parasitic Sensitivity Tests; Pyrimethamine; Quantitative Structure-Activity Relationship; Riluzole; Small Molecule Libraries; Tetrahydrofolate Dehydrogenase; Trypanocidal Agents | 2011 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Riluzole prevents hyperexcitability produced by the mast cell degranulating peptide and dendrotoxin I in the rat.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Elapid Venoms; Electroencephalography; Hippocampus; Injections, Intraventricular; Male; Peptides; Rats; Rats, Inbred Strains; Riluzole; Seizures; Thiazoles | 1991 |
Riluzole interacts with voltage-activated sodium and potassium currents in cultured rat cortical neurons.
Topics: 4-Aminopyridine; Animals; Cadmium; Cells, Cultured; Cerebral Cortex; Electric Stimulation; Ion Channel Gating; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Potassium; Potassium Channels; Rats; Rats, Wistar; Riluzole; Sodium; Sodium Channels; Tetraethylammonium | 1998 |
Taurine release is enhanced in cell-damaging conditions in cultured cerebral cortical astrocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Free Radicals; Oxidative Stress; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Riluzole; Taurine | 1999 |
Evidence that DHPG-induced nociception depends on glutamate release from primary afferent C-fibres.
Topics: 4-Aminopyridine; Animals; Behavior, Animal; Capsaicin; Excitatory Amino Acid Agonists; Glutamic Acid; Injections, Spinal; Lamotrigine; Male; Methoxyhydroxyphenylglycol; Nerve Fibers; Neurons, Afferent; Nociceptors; Proline; Propionates; Rats; Rats, Long-Evans; Riluzole; Triazines | 2000 |
Seizures and neurodegeneration induced by 4-aminopyridine in rat hippocampus in vivo: role of glutamate- and GABA-mediated neurotransmission and of ion channels.
Topics: 4-Aminopyridine; Animals; Epilepsy; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Ion Channels; Male; Nerve Degeneration; Neurons; Neurotoxins; omega-Conotoxin GVIA; Potassium Channels; Rats; Rats, Wistar; Receptors, Glutamate; Riluzole; Seizures; Sodium Channel Blockers; Sodium Channels; Synaptic Transmission | 2000 |
Pharmacological modulation of SK3 channels.
Topics: 4-Aminopyridine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Apamin; Bicuculline; Cell Line; Humans; Neuroprotective Agents; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Riluzole; Small-Conductance Calcium-Activated Potassium Channels | 2001 |
Involvement of persistent Na+ current in spike initiation in primary sensory neurons of the rat mesencephalic trigeminal nucleus.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Lidocaine; Neurons, Afferent; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Riluzole; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Trigeminal Nuclei | 2007 |
Transition between two excitabilities in mesencephalic V neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Biological Clocks; Cell Membrane; Computer Simulation; Excitatory Amino Acid Antagonists; Ion Channels; Isoquinolines; Neurons; Organ Culture Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Riluzole; Sodium Channels; Staining and Labeling; Synaptic Transmission; Trigeminal Nuclei | 2008 |