4-aminopyridine has been researched along with physostigmine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (57.14) | 18.7374 |
| 1990's | 11 (39.29) | 18.2507 |
| 2000's | 1 (3.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Artusio, JF; Okamoto, M; Riker, WF; Walewski, JL | 1 |
| Ikeda, T; Iwasaki, H; Kishi, R; Mimura, M; Miyake, H; Namiki, A | 1 |
| Furukawa, T; Katsuragi, T; Ogawa, S; Shirakabe, K; Soejima, O | 1 |
| Kiraly, M; Liao, GS; Maillard, M | 1 |
| Töröcsik, A; Vizi, ES | 1 |
| Cook, L; DeNoble, KF; DeNoble, VJ; Johnson, LC; Myers, MJ; Scribner, RM; Spencer, KR | 1 |
| Cumming, P; Reiner, PB; Vincent, SR | 1 |
| Hatch, RC; Jernigan, AD | 1 |
| Aceves, J; Góngora, JL; Mariscal, S; Sierra, A | 1 |
| Genovese, N; Klawans, HL | 1 |
| Campbell, GA; Davis, KL; Haroutunian, V; Kanof, PD; Tsuboyama, GK | 1 |
| Guerrero, S; Zacharias, J | 1 |
| Barnes, E; Davis, KL; Haroutunian, V | 1 |
| Araujo, DM; Collier, B; Rícný, J; Welner, SA | 1 |
| Davis, KL; Hollander, E; Mohs, RC | 1 |
| Frossard, N; Muller, F | 1 |
| Gibson, GE; Pelmas, CJ; Peterson, C | 1 |
| Xu, JH; Yang, BZ; Zhou, HJ | 1 |
| Saith, S; Schofield, JG | 1 |
| Agoston, S; Langrehr, D; Schmutzler, S; Uges, D | 1 |
| Dzoljic, MR; Rupreht, J | 1 |
| Martinez-Aguirre, E | 1 |
| Beninger, RJ; Boegman, RJ; Jhamandas, K; Mallet, PE; Wirsching, BA | 1 |
| Nordberg, A; Xiao, WB; Zhang, X | 1 |
| Farlow, MR; Greig, NH; Lahiri, DK; Nurnberger, JI | 1 |
| Bernardi, G; Bonci, A; Grillner, P; Mercuri, NB; Svensson, TH | 1 |
2 review(s) available for 4-aminopyridine and physostigmine
| Article | Year |
|---|---|
Pharmacology of dementia.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine Triphosphate; Aged; Aminopyridines; Central Nervous System Stimulants; Cerebrovascular Circulation; Clinical Trials as Topic; Dementia; Double-Blind Method; Humans; Levodopa; Nafronyl; Narcotic Antagonists; Nerve Tissue Proteins; Parasympathomimetics; Pentylenetetrazole; Physostigmine; Piracetam; Procainamide; Vasodilator Agents; Vasopressins | 1986 |
Cholinergic approaches to the treatment of Alzheimer's disease.
Topics: 4-Aminopyridine; Alanine; Alzheimer Disease; Aminopyridines; Arecoline; Clinical Trials as Topic; Humans; Parasympathomimetics; Physostigmine; Piracetam; Pyrrolidines; Research Design; Succinimides; Synapses | 1986 |
2 trial(s) available for 4-aminopyridine and physostigmine
| Article | Year |
|---|---|
Pharmacology of dementia.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine Triphosphate; Aged; Aminopyridines; Central Nervous System Stimulants; Cerebrovascular Circulation; Clinical Trials as Topic; Dementia; Double-Blind Method; Humans; Levodopa; Nafronyl; Narcotic Antagonists; Nerve Tissue Proteins; Parasympathomimetics; Pentylenetetrazole; Physostigmine; Piracetam; Procainamide; Vasodilator Agents; Vasopressins | 1986 |
Cholinergic approaches to the treatment of Alzheimer's disease.
Topics: 4-Aminopyridine; Alanine; Alzheimer Disease; Aminopyridines; Arecoline; Clinical Trials as Topic; Humans; Parasympathomimetics; Physostigmine; Piracetam; Pyrrolidines; Research Design; Succinimides; Synapses | 1986 |
26 other study(ies) available for 4-aminopyridine and physostigmine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Neuromuscular pharmacology in rat neonates: development of responsiveness to prototypic blocking and reversal drugs.
Topics: 4-Aminopyridine; Aging; Animals; Animals, Newborn; Cholinesterase Inhibitors; Curare; Dose-Response Relationship, Drug; Drug Synergism; Edrophonium; Fasciculation; Female; Male; Muscle Contraction; Neostigmine; Nerve Endings; Neuromuscular Blocking Agents; Neuromuscular Junction; Physostigmine; Rats; Rats, Inbred Strains; Succinylcholine; Synaptic Transmission; Tubocurarine | 1992 |
Central cholinergic action produces antagonism to ketamine anesthesia.
Topics: 4-Aminopyridine; Anesthesia, General; Animals; Atropine; Ketamine; Male; Oxotremorine; Parasympathomimetics; Physostigmine; Rats; Rats, Inbred Strains | 1992 |
Involvement of dihydropyridine-sensitive Ca2+ channels in adenosine-evoked inhibition of acetylcholine release from guinea pig ileal preparation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Acetylcholine; Adenosine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Calcium Channels; Chromatography, High Pressure Liquid; Dihydropyridines; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle, Smooth; Nifedipine; Physostigmine; Tetrodotoxin; Theophylline | 1990 |
Ion channels involved in the presynaptic hyperexcitability induced by herpes virus suis in rat superior cervical ganglion.
Topics: 4-Aminopyridine; Action Potentials; Animals; Atropine; Calcium Channel Blockers; Electric Stimulation; Evoked Potentials; Ganglia, Sympathetic; Herpesvirus 1, Suid; Hexamethonium; Hexamethonium Compounds; Ion Channels; Male; Neurons; Physostigmine; Pirenzepine; Pseudorabies; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin | 1991 |
4-Aminopyridine interrupts the modulation of acetylcholine release mediated by muscarinic and opiate receptors.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Atropine; Brain; Electric Stimulation; Enkephalin, Methionine; In Vitro Techniques; Male; Oxotremorine; Physostigmine; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Opioid | 1990 |
Comparison of DuP 996, with physostigmine, THA and 3,4-DAP on hypoxia-induced amnesia in rats.
Topics: 4-Aminopyridine; Amnesia; Animals; Avoidance Learning; Hypoxia; Indoles; Male; Oxygen Consumption; Parasympathetic Nervous System; Physostigmine; Pyridines; Rats; Rats, Inbred Strains; Tacrine | 1990 |
Inhibition of rat brain histamine-N-methyltransferase by 9-amino-1,2,3,4-tetrahydroacridine (THA).
Topics: 4-Aminopyridine; Aminoacridines; Animals; Antineoplastic Agents; Brain; Histamine; Histamine N-Methyltransferase; Injections, Intraperitoneal; Male; Methyltransferases; Physostigmine; Pyrimethamine; Rats; Tacrine | 1990 |
Effect of intravenously-administered putative and potential antagonists of ethanol on sleep time in ethanol-narcotized mice.
Topics: 4-Aminopyridine; Alcoholic Intoxication; Aminophylline; Aminopyridines; Amphetamine; Animals; Azides; Benzodiazepines; Dextroamphetamine; Doxapram; Ethanol; Male; Mice; Naloxone; Physostigmine; Propranolol; Sleep; Thyrotropin-Releasing Hormone; Yohimbine | 1988 |
Physostigmine stimulates phosphoinositide breakdown in the rat neostriatum.
Topics: 4-Aminopyridine; Acetylcholinesterase; Aminopyridines; Animals; Cholinesterase Inhibitors; Corpus Striatum; Male; Parasympathomimetics; Phosphatidylinositols; Physostigmine; Rats; Rats, Inbred Strains | 1988 |
Animal models of Alzheimer's disease: behavior, pharmacology, transplants.
Topics: 4-Aminopyridine; Alzheimer Disease; Aminopyridines; Animals; Behavior, Animal; Brain; Disease Models, Animal; Fetus; Growth Substances; Humans; Nerve Growth Factors; Nerve Tissue; Nerve Tissue Proteins; Nervous System Diseases; Norepinephrine; Parasympathetic Nervous System; Physostigmine; Somatostatin | 1986 |
Effects of cholinergic drugs and 4-aminopyridine on cat ciliary muscle contractility.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Carbachol; Cats; Ciliary Body; Muscle Contraction; Parasympathomimetics; Physostigmine; Tetrodotoxin | 1985 |
Cholinergic modulation of memory in rats.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Arecoline; Brain; Cholinergic Fibers; Male; Memory; Nicotine; Oxotremorine; Physostigmine; Rats; Rats, Inbred Strains; Retention, Psychology | 1985 |
Acetylcholine synthesis and release by a sympathetic ganglion in the presence of 2-(4-phenylpiperidino) cyclohexanol (AH5183).
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Calcium; Cats; Electric Stimulation; Female; Ganglia, Sympathetic; Kinetics; Male; Phencyclidine; Physostigmine; Piperidines | 1986 |
Epithelial modulation of tracheal smooth muscle response to antigenic stimulation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Antigens; Atropine; Capsaicin; Epithelium; Male; Microscopy, Electron, Scanning; Muscle Contraction; Muscle, Smooth; Ovalbumin; Physostigmine; Rats; Rats, Inbred Strains; Trachea | 1986 |
Cholinergic drugs and 4-aminopyridine alter hypoxic-induced behavioral deficits.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Arecoline; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Drug Interactions; Hexamethonium; Hexamethonium Compounds; Hypoxia; Male; Mecamylamine; Mice; Motor Activity; Nicotine; Parasympathomimetics; Physostigmine; Structure-Activity Relationship | 1983 |
[Antagonism of 4-aminopyridine on the central nervous system depressant effects of scopolamine in rabbits].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Central Nervous System Depressants; Central Nervous System Stimulants; Electroencephalography; Female; Male; Physostigmine; Rabbits; Scopolamine | 1984 |
Potentiation of bovine growth hormone release by an inhibitor of potassium channels.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Cattle; Drug Synergism; Growth Hormone; In Vitro Techniques; Ion Channels; Physostigmine; Pituitary Gland; Potassium | 1981 |
[Rohypnol poisoning as a cause of postanesthetic coma and the success of 4-aminopyridine therapy].
Topics: 4-Aminopyridine; Adult; Aminopyridines; Anesthesia; Coma; Female; Flunitrazepam; Humans; Naloxone; Physostigmine; Postoperative Complications | 1984 |
The role of a noradrenergic system in the antinociceptive effects of 4-aminopyridine in the rat.
Topics: 4-Aminopyridine; Aminopyridines; Analgesics; Animals; Cholinesterase Inhibitors; Male; Norepinephrine; Physostigmine; Rats; Rats, Inbred Strains | 1983 |
Antagonism of ketamine by 4-aminopyridine and physostigmine.
Topics: 4-Aminopyridine; Aminopyridines; Humans; Ketamine; Physostigmine | 1982 |
Antagonism of ketamine by 4-aminopyridine and physostigmine.
Topics: 4-Aminopyridine; Aminopyridines; Drug Interactions; Humans; Ketamine; Physostigmine | 1981 |
Physostigmine, but not 3,4-diaminopyridine, improves radial maze performance in memory-impaired rats.
Topics: 4-Aminopyridine; Amifampridine; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Physostigmine; Potassium Channels; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Scopolamine | 1995 |
Effect of in vivo microdialysis of 1,2,3,4-tetrahydro-9-aminoacridine (THA) on the extracellular concentration of acetylcholine in the striatum of anesthetized rats.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Cholinesterase Inhibitors; Corpus Striatum; Dialysis; Male; Physostigmine; Potassium; Rats; Rats, Sprague-Dawley; Tacrine | 1993 |
Effects of cholinesterase inhibitors on the secretion of beta-amyloid precursor protein in cell cultures.
Topics: 4-Aminopyridine; Amifampridine; Amyloid beta-Protein Precursor; Animals; Cholinesterase Inhibitors; HeLa Cells; Humans; PC12 Cells; Physostigmine; Rats; Tacrine; Trichlorfon; Tumor Cells, Cultured | 1997 |
Presynaptic muscarinic (M3) receptors reduce excitatory transmission in dopamine neurons of the rat mesencephalon.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Atropine; Carbachol; Diamines; Dicyclomine; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Mesencephalon; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Parasympatholytics; Physostigmine; Piperidines; Pirenzepine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Receptor, Muscarinic M3; Receptors, Muscarinic; Synaptic Transmission; Tetrodotoxin | 1999 |