4-aminopyridine has been researched along with phenobarbital in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Sen, S; Sinha, N | 1 |
| Duburs, G; Germane, SK; Karpova, MN; Klusha, VE; Pankov, OIu | 1 |
| Brückner, C; Heinemann, U | 1 |
| Baraban, SC; Barbaro, NM; Smyth, MD | 1 |
| Errington, AC; Lees, G; Stöhr, T | 1 |
| Hill, AJ; Jones, NA; Stephens, GJ; Whalley, BJ; Williams, CM | 1 |
8 other study(ies) available for 4-aminopyridine and phenobarbital
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
[The antiepileptic effects of the combined action of the new 1,4-dihydropyridine derivative glutapyrone with sodium valproate and phenobarbital].
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Dihydropyridines; Drug Evaluation, Preclinical; Drug Therapy, Combination; Electroshock; Epilepsies, Partial; Epilepsy, Generalized; Glutamates; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Phenobarbital; Rats; Rats, Wistar; Valproic Acid | 1993 |
Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamazepine; Entorhinal Cortex; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Male; Pentobarbital; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Valproic Acid | 2000 |
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Disease Models, Animal; Electroencephalography; Epilepsy; Ethosuximide; Female; Hippocampus; In Vitro Techniques; Lamotrigine; Methylazoxymethanol Acetate; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazines; Valproic Acid | 2002 |
Stereoselective effects of the novel anticonvulsant lacosamide against 4-AP induced epileptiform activity in rat visual cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetamides; Animals; Anticonvulsants; Carbamazepine; Convulsants; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Space; Female; In Vitro Techniques; Lacosamide; Male; Membrane Potentials; Patch-Clamp Techniques; Phenobarbital; Picrotoxin; Potassium Channel Blockers; Prohibitins; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Visual Cortex | 2006 |
Development of multi-electrode array screening for anticonvulsants in acute rat brain slices.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Anticonvulsants; Disease Models, Animal; Drug Evaluation, Preclinical; Electrodes; Electrophysiology; Epilepsy; Felbamate; Female; Hippocampus; In Vitro Techniques; Magnesium Deficiency; Membrane Potentials; Phenobarbital; Phenylcarbamates; Propylene Glycols; Rats; Rats, Wistar; Time Factors | 2010 |