4-aminopyridine has been researched along with oxadiazoles in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Massieu, L; Tapia, R | 1 |
| Cook, NS | 1 |
| Carvalho, AP; Carvalho, CM; Sequeira, SM | 1 |
| Faraci, FM; Sobey, CG | 1 |
| Bryan, RM; Johnson, TD; Marrelli, SP; Mombouli, JV; You, J | 1 |
| Gordon, JB; Halla, TR; Madden, JA | 1 |
| Cole, WC; Dong, H; Jiang, Y; Triggle, CR | 1 |
| Garland, CJ; Plane, F; Sampson, LJ; Smith, JJ | 1 |
| Ishikawa, T; Kaneko, Y; Nakayama, K; Sugino, F | 1 |
| Chu, V; Janssen, LJ; Tazzeo, T; Zhang, Y | 1 |
| Breschi, MC; Calderone, V; Martelli, A; Martinotti, E; Testai, L | 1 |
| Baggio, CH; Cipriani, TR; da Silva-Santos, JE; de Souza, LM; Freitas, CS; Graça, C; Marques, MC; Pontarolo, R; Rattmann, YD; Rieck, L; Sassaki, GL | 1 |
| Chen, J; Chen, X; Liu, J; Wang, T; Xiao, H; Yang, J; Ye, Z; Yin, C | 1 |
| Favaloro, JL; Kemp-Harper, BK | 1 |
| Aaronson, PI; Knock, GA; Kua, J; Smirnov, SV; Snetkov, VA; Ward, JP | 1 |
| Centurión, D; Cobos-Puc, LE; González-Hernández, A; Maassenvandenbrink, A; Muñoz-Islas, E; Ramírez-Rosas, MB; Sánchez-López, A; Villalón, CM | 1 |
| Dash, JR; Parija, SC | 1 |
| Bae, H; Bang, H; Kim, JH; Kim, K; Kim, T; Ko, JH; Lee, HJ; Lim, I | 1 |
18 other study(ies) available for 4-aminopyridine and oxadiazoles
| Article | Year |
|---|---|
Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aminopyridines; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; gamma-Aminobutyric Acid; Ion Channels; Isradipine; Lanthanum; Male; Mice; Neurotransmitter Agents; Nifedipine; Nitrendipine; Oxadiazoles; Potassium; Receptors, Nicotinic; Ruthenium Red; Synaptosomes | 1988 |
Effect of some potassium channel blockers on contractile responses of the rabbit aorta.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Aorta, Thoracic; Apamin; Calcium Channel Blockers; Endothelium, Vascular; Female; In Vitro Techniques; Isradipine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxadiazoles; Potassium Channels; Rabbits; Scorpion Venoms; Tetraethylammonium Compounds | 1989 |
Both protein kinase G dependent and independent mechanisms are involved in the modulation of glutamate release by nitric oxide in rat hippocampal nerve terminals.
Topics: 4-Aminopyridine; Animals; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Nitric Oxide; Nitroprusside; Oxadiazoles; Presynaptic Terminals; Protein Kinases; Quinoxalines; Rats; Sulfhydryl Reagents; Synaptosomes; Thionucleotides | 1999 |
Inhibitory effect of 4-aminopyridine on responses of the basilar artery to nitric oxide.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine Triphosphate; Animals; Basilar Artery; Cromakalim; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Male; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Papaverine; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 1999 |
P2u receptor-mediated release of endothelium-derived relaxing factor/nitric oxide and endothelium-derived hyperpolarizing factor from cerebrovascular endothelium in rats.
Topics: 4-Aminopyridine; Animals; Apamin; Barium Compounds; Cerebral Arteries; Cerebrovascular Circulation; Charybdotoxin; Chlorides; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Peptides; Potassium Channels; Potassium Chloride; Quinoxalines; Rats; Rats, Long-Evans; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Tetraethylammonium; Uridine Triphosphate; Vasodilation | 1999 |
Mediators of alkalosis-induced relaxation of piglet pulmonary veins.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Alkalosis; Animals; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Nitric Oxide; Nitroarginine; Oxadiazoles; Peptides; Potassium Channels; Pulmonary Veins; Quinoxalines; Swine; Vasoconstrictor Agents; Vasodilation | 2000 |
Comparison of the pharmacological properties of EDHF-mediated vasorelaxation in guinea-pig cerebral and mesenteric resistance vessels.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Arachidonic Acids; Biological Factors; Cerebral Arteries; Charybdotoxin; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Ouabain; Oxadiazoles; Potassium Channel Blockers; Potassium Channels; Quinoxalines; Vasodilation; Vasodilator Agents | 2000 |
Relaxation to authentic nitric oxide and SIN-1 in rat isolated mesenteric arteries: variable role for smooth muscle hyperpolarization.
Topics: 4-Aminopyridine; Animals; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Membrane Potentials; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Peptides; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Vasodilation | 2001 |
Two distinct effects of cGMP on cytosolic Ca2+ concentration of rat pancreatic beta-cells.
Topics: 4-Aminopyridine; Animals; Calcium; Cyclic GMP; Cytosol; Dimethyl Sulfoxide; Enzyme Inhibitors; Glucose; Hydrazines; Hypoglycemic Agents; Islets of Langerhans; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Potassium; Potassium Channel Blockers; Quinoxalines; Rats; Tolbutamide | 2003 |
Membrane potassium currents in human radial artery and their regulation by nitric oxide donor.
Topics: 4-Aminopyridine; Adult; Aged; Aged, 80 and over; Blotting, Western; Female; Glyburide; Guanylate Cyclase; Humans; In Vitro Techniques; Ion Channel Gating; Male; Membrane Potentials; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide Donors; Oxadiazoles; Patch-Clamp Techniques; Penicillamine; Peptides; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Quinoxalines; Radial Artery; Tetraethylammonium Compounds | 2006 |
Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels.
Topics: 4-Aminopyridine; Animals; Aorta, Thoracic; Benzimidazoles; Calcium Channel Blockers; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Peptides; Potassium Chloride; Quinoxalines; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2007 |
In vivo assessment of safety and mechanisms underlying in vitro relaxation induced by Mikania laevigata Schultz Bip. ex Baker in the rat trachea.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Brazil; Coumarins; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Glyburide; In Vitro Techniques; Male; Mice; Mikania; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Oxadiazoles; Plant Extracts; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Tetraethylammonium; Toxicity Tests, Acute; Toxicity Tests, Chronic; Trachea | 2007 |
The relaxation mechanisms of tetrandrine on the rabbit corpus cavernosum tissue in vitro.
Topics: 4-Aminopyridine; Animals; Benzylisoquinolines; Drugs, Chinese Herbal; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth; Nitroarginine; Oxadiazoles; Penis; Potassium Channel Blockers; Potassium Chloride; Quinoxalines; Rabbits; Stephania tetrandra; Tetraethylammonium | 2009 |
Redox variants of NO (NO{middle dot} and HNO) elicit vasorelaxation of resistance arteries via distinct mechanisms.
Topics: 4-Aminopyridine; Animals; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vascular Resistance; Vasodilation; Vasodilator Agents | 2009 |
Superoxide differentially controls pulmonary and systemic vascular tone through multiple signalling pathways.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Aminoquinolines; Animals; Calcium Signaling; Guanylate Cyclase; In Vitro Techniques; Male; Mesenteric Arteries; Myocytes, Smooth Muscle; Oxadiazoles; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pulmonary Artery; Quinoxalines; Rats; Rats, Wistar; rho-Associated Kinases; Superoxides; Vasoconstriction; Vasoconstrictor Agents | 2011 |
Pharmacological evidence that Ca²+ channels and, to a lesser extent, K+ channels mediate the relaxation of testosterone in the canine basilar artery.
Topics: 4-Aminopyridine; Adenine; Aminoglutethimide; Androgen Receptor Antagonists; Animals; Aromatase Inhibitors; Barium Compounds; Basilar Artery; Calcium Channel Blockers; Calcium Channels; Chlorides; Cycloheximide; Dactinomycin; Dogs; Enzyme Inhibitors; Flutamide; In Vitro Techniques; Male; Nifedipine; Nucleic Acid Synthesis Inhibitors; Oxadiazoles; Potassium Channel Blockers; Potassium Channels; Protein Synthesis Inhibitors; Quinoxalines; Testosterone; Vasodilation; Vasodilator Agents | 2011 |
Spasmolytic effect of curcumin on goat ruminal artery is endothelium independent and by activation of sGC.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Curcumin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Goats; Guanylate Cyclase; NG-Nitroarginine Methyl Ester; Nitroprusside; Oxadiazoles; Receptors, Cytoplasmic and Nuclear; Rumen; Serotonin; Soluble Guanylyl Cyclase; Tissue Culture Techniques; Vasoconstriction | 2013 |
The stimulating effects of nitric oxide on intermediate conductance Ca²⁺-activated K⁺ channels in human dermal fibroblasts through PKG pathways but not the PKA pathways.
Topics: 4-Aminopyridine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dermis; Enzyme Inhibitors; Fibroblasts; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Nitric Oxide; Oxadiazoles; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Quinoxalines; Signal Transduction; Toxins, Biological; Wound Healing | 2014 |