4-aminopyridine and naloxone

4-aminopyridine has been researched along with naloxone in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (63.16)	18.7374
1990's	1 (5.26)	18.2507
2000's	6 (31.58)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bondy, CA; Russell, JT	1
Hatch, RC; Jernigan, AD	1
Altes, U; Baur, AM; Jost, D; Racké, K; Schäfer, J	1
Altes, U; Baur, AM; Hobbach, HP; Jost, D; Racké, K; Schäfer, J; Wammack, R	1
Booth, NH; Brown, J; Clark, JD; Hatch, RC; Jernigan, AD; Lipham, IB; Wilson, RC	1
Baklavadzhian, OG; Darbinian, AG; Ipekchian, NM; Taturian, IKh	1
Booth, NH; Crawford, LM; Hatch, RC	1
Clark, JD; Hatch, RC; Kitzman, JV; Zahner, JM	1
Illes, P; Kromer, W; Scheiblhuber, E	1
Agoston, S; Langrehr, D; Schmutzler, S; Uges, D	1
Booth, NH; Clark, JD; Hatch, RC; Kitzman, JV	1
Crain, B; Crain, SM; Peterson, ER	1
Ducker, TB; Ellenbogen, RG; Ling, GS; Zeidman, SM	1
Hata, F; Nishio, H; Nishiwaki, H; Saitoh, N; Takeuch, T	1
Enginar, N; Kara , I; Koyuncuoğlu, H; Nurten, A; Ozerman, B	1
Hung, CF; Lee, YJ; Su, MJ; Wang, SJ; Yang, TT	1
Castañeda-Hernández, G; Castro-Olguín, J; Ortiz, MI; Peña-Samaniego, N	1
Granados-Soto, V; Medina-Tato, DA; Ortiz, MI; Palma-Martínez, J; Sarmiento-Heredia, D	1
Haji, A; Kato, F; Ohi, Y	1

Reviews

1 review(s) available for 4-aminopyridine and naloxone

Article	Year
Clinical applications of pharmacologic therapies for spinal cord injury. Journal of spinal disorders, 1996, Volume: 9, Issue:5 Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation, Preclinical; Free Radical Scavengers; G(M1) Ganglioside; Glucocorticoids; Humans; Methylprednisolone; Multicenter Studies as Topic; Naloxone; Neuroprotective Agents; Pregnatrienes; Randomized Controlled Trials as Topic; Spinal Cord Injuries; Treatment Outcome	1996

Article

Year

Clinical applications of pharmacologic therapies for spinal cord injury.

Journal of spinal disorders, 1996, Volume: 9, Issue:5

Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation, Preclinical; Free Radical Scavengers; G(M1) Ganglioside; Glucocorticoids; Humans; Methylprednisolone; Multicenter Studies as Topic; Naloxone; Neuroprotective Agents; Pregnatrienes; Randomized Controlled Trials as Topic; Spinal Cord Injuries; Treatment Outcome

1996

Other Studies

18 other study(ies) available for 4-aminopyridine and naloxone

Article	Year
Dendrotoxin and 4-aminopyridine potentiate neurohypophysial hormone secretion during low frequency electrical stimulation. Brain research, 1988, Jun-21, Volume: 453, Issue:1-2 Topics: 4-Aminopyridine; Aminopyridines; Animals; Elapid Venoms; Electric Stimulation; In Vitro Techniques; Ion Channels; Male; Naloxone; Oxytocin; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Vasopressins	1988
Effect of intravenously-administered putative and potential antagonists of ethanol on sleep time in ethanol-narcotized mice. Life sciences, 1988, Volume: 42, Issue:1 Topics: 4-Aminopyridine; Alcoholic Intoxication; Aminophylline; Aminopyridines; Amphetamine; Animals; Azides; Benzodiazepines; Dextroamphetamine; Doxapram; Ethanol; Male; Mice; Naloxone; Physostigmine; Propranolol; Sleep; Thyrotropin-Releasing Hormone; Yohimbine	1988
Tetraethylammonium ions and 4-aminopyridine prevent opioid inhibition of neurohypophysial oxytocin release. Brain research, 1987, Dec-15, Volume: 436, Issue:2 Topics: 4-Aminopyridine; Aminopyridines; Animals; Electric Stimulation; Etorphine; Female; Naloxone; Oxytocin; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds	1987
Differential effects of potassium channel blockers on neurohypophysial release of oxytocin and vasopressin. Evidence for frequency-dependent interaction with the endogenous opioid inhibition of oxytocin release. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:5 Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Benzopyrans; Cromakalim; Electric Stimulation; Endorphins; Female; Naloxone; Oxytocin; Pituitary Gland, Posterior; Potassium Channels; Pyrroles; Radioimmunoassay; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds; Vasopressins	1988
Prompt arousal from fentanyl-droperidol-pentobarbital anesthesia in dogs: a preliminary study. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1986, Volume: 50, Issue:2 Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Anesthetics; Animals; Arousal; Dogs; Doxapram; Droperidol; Drug Combinations; Fentanyl; Naloxone; Pentobarbital; Yohimbine	1986
[Neuronal and neurochemical mechanisms of hypothalamic inhibition of the pain reflex]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1987, Volume: 73, Issue:9 Topics: 4-Aminopyridine; Analgesics; Animals; Cats; Hypothalamus; Naloxone; Pain; Periaqueductal Gray; Reflex	1987
Reversal of the neuroleptanalgesic effect of droperidolfentanyl in the dog by 4-aminopyridine and naloxone. American journal of veterinary research, 1982, Volume: 43, Issue:7 Topics: 4-Aminopyridine; Aminopyridines; Animals; Blood Pressure; Cardiovascular Agents; Central Nervous System Stimulants; Dogs; Droperidol; Drug Combinations; Drug Therapy, Combination; Female; Fentanyl; Heart Rate; Male; Naloxone; Respiration; Yohimbine	1982
Comparison of five preanesthetic medicaments in thiopental-anesthetized cats: antagonism by selected compounds. American journal of veterinary research, 1984, Volume: 45, Issue:11 Topics: 4-Aminopyridine; Acepromazine; Aminopyridines; Anesthesia, General; Animals; Arousal; Benzodiazepinones; Cats; Central Nervous System Stimulants; Convulsants; Diazepam; Drug Antagonism; Female; Flumazenil; Ketamine; Male; Meperidine; Naloxone; Pentobarbital; Preanesthetic Medication; Sodium Chloride; Xylazine; Yohimbine	1984
Functional antagonism by calcium of an intrinsic opioid mechanism in the guinea-pig isolated ileum. Neuropharmacology, 1980, Volume: 19, Issue:9 Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Peristalsis; Receptors, Opioid	1980
[Rohypnol poisoning as a cause of postanesthetic coma and the success of 4-aminopyridine therapy]. Der Anaesthesist, 1984, Volume: 33, Issue:6 Topics: 4-Aminopyridine; Adult; Aminopyridines; Anesthesia; Coma; Female; Flunitrazepam; Humans; Naloxone; Physostigmine; Postoperative Complications	1984
Comparison of five preanesthetic medicaments in pentobarbital-anesthetized dogs: antagonism by 4-aminopyridine, yohimbine, and naloxone. American journal of veterinary research, 1983, Volume: 44, Issue:12 Topics: 4-Aminopyridine; Aminopyridines; Anesthesia, General; Animals; Dogs; Drug Combinations; Female; Heart Rate; Male; Naloxone; Neuromuscular Depolarizing Agents; Pentobarbital; Preanesthetic Medication; Respiration; Yohimbine	1983
Development of cross-tolerance to 5-hydroxytryptamine in organotypic cultures of mouse spinal cord-ganglia during chronic exposure to morphine. Life sciences, 1982, Jul-19, Volume: 31, Issue:3 Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Drug Tolerance; Ganglia, Spinal; Mice; Morphine; Naloxone; Organ Culture Techniques; Serotonin; Spinal Cord	1982
Possible role of potassium channels in mu-receptor-mediated inhibition and muscarinic autoinhibition in acetylcholine release from myenteric plexus of guinea pig ileum. Japanese journal of pharmacology, 2000, Volume: 82, Issue:4 Topics: 4-Aminopyridine; Acetylcholine; Analgesics, Opioid; Animals; Apamin; Atropine; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Glyburide; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscarinic Antagonists; Myenteric Plexus; Naloxone; Narcotic Antagonists; Neuromuscular Junction; Peptides; Potassium Channel Blockers; Potassium Channels; Receptors, Muscarinic; Receptors, Opioid, mu; Tetraethylammonium	2000
The effects of different 4-aminopyridine and morphine combinations on the intensity of morphine abstinence. Pharmacological research, 2001, Volume: 43, Issue:3 Topics: 4-Aminopyridine; Animals; Behavior, Animal; Calcium; Disease Models, Animal; Glutamic Acid; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	2001
Morphine inhibits glutamate exocytosis from rat cerebral cortex nerve terminals (synaptosomes) by reducing Ca2+ influx. Synapse (New York, N.Y.), 2004, Volume: 51, Issue:2 Topics: 4-Aminopyridine; Analgesics, Opioid; Animals; Benzothiazoles; Benzoxazines; Calcium; Calcium Channel Blockers; Carbocyanines; Cerebral Cortex; Dose-Response Relationship, Drug; Exocytosis; Fluorometry; Fura-2; Glutamic Acid; Ionomycin; Ionophores; Male; Membrane Potentials; Morphine; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Synaptosomes	2004
Probable activation of the opioid receptor-nitric oxide-cyclic GMP-K+ channels pathway by codeine. Pharmacology, biochemistry, and behavior, 2005, Volume: 82, Issue:4 Topics: 4-Aminopyridine; Analgesics, Opioid; Animals; Codeine; Cyclic GMP; Female; Glyburide; Methylene Blue; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rats; Rats, Wistar; Receptors, Opioid; Tetraethylammonium; Tolbutamide	2005
Possible activation of the NO-cyclic GMP-protein kinase G-K+ channels pathway by gabapentin on the formalin test. Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:3 Topics: 4-Aminopyridine; Amines; Analgesics; Animals; Apamin; Carbazoles; Charybdotoxin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Indoles; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Tolbutamide	2006
Codeine presynaptically inhibits the glutamatergic synaptic transmission in the nucleus tractus solitarius of the guinea pig. Neuroscience, 2007, May-25, Volume: 146, Issue:3 Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Codeine; Data Interpretation, Statistical; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Guinea Pigs; Male; Membrane Potentials; Naloxone; Narcotic Antagonists; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Receptors, AMPA; Receptors, Presynaptic; Solitary Nucleus; Synaptic Transmission	2007