4-aminopyridine has been researched along with n-methylaspartate in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.44) | 18.7374 |
| 1990's | 21 (46.67) | 18.2507 |
| 2000's | 15 (33.33) | 29.6817 |
| 2010's | 6 (13.33) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Fragoso-Veloz, J; Tapia, R | 1 |
| Fredholm, BB; Hu, PS; Jin, S | 1 |
| Fink, K; Göthert, M; Schlicker, E | 1 |
| Aniksztejn, L; Ben-Ari, Y | 1 |
| Haberly, LB; Hoffman, WH | 1 |
| de Carolis, AS; Frank, C; Sagratella, S | 1 |
| Jahr, CE; Tong, G | 1 |
| Burnett, JP; Desai, MA; Schoepp, DD | 1 |
| Gross, GW; Rhoades, BK | 1 |
| Boos, R; Schneider, H; Wässle, H | 1 |
| Barrionuevo, G; Fleck, MW; Henze, DA; Palmer, AM | 1 |
| Avoli, M; Köhling, R; Lücke, A; Nagao, T | 1 |
| Ghosh, P; Liljelund, P; van den Pol, AN | 1 |
| Chuang, DM; Ishitani, R; Sunaga, K | 1 |
| Avoli, M; Barbarosie, M; Köhling, R; Lopantsev, V; Lücke, A; Nagao, T | 1 |
| Avoli, M; Lopantsev, V | 1 |
| Hu, PS; Ross, SB | 1 |
| Andersen, PH; Burns, CM; Chang, H; Crider, AM; el-Assadi, AA; Hinko, CN; Ho, B; Kliem, MA; Klitgaard, H; Seo, TH; Steinmiller, CL; Tietz, EI; Venkatarangan, P | 1 |
| Tapia, R | 1 |
| Balestra, M; Borrelli, AR; Cramer, CL; Eismann, MS; Freedman, LR; Hudzik, TJ; Knowles, MK; Mahmood, N; McCarthy, DJ; Murray, RJ; Palmer, GC; Stagnitto, ML | 1 |
| Cazalets, JR; Magoul, R; Sqalli-Houssaini, Y | 1 |
| Boychuk, YA; Kopanitsa, MV; Krishtal, OA; Lozovaya, NA | 1 |
| Beato, M; Nistri, A | 1 |
| El Manira, A; Hess, D | 1 |
| Carvalho, AP; Carvalho, CM; Malva, JO; Sequeira, SM | 1 |
| Anderson, JW; Bains, JS; Ferguson, AV; Follwell, MJ; Latchford, KJ | 1 |
| Gray, R; Johnston, D; Liang, Y; Yuan, LL | 1 |
| Ge, SY; Gu, Y; Ruan, DY | 1 |
| Grebenyuk, S; Kirichok, Y; Krishtal, O; Lozovaya, N; Melnik, S; Tsintsadze, T | 1 |
| Domenici, MR; Frank, C; Grieco, R; Martire, A; Pepponi, R; Pintor, A; Popoli, P; Potenza, RL; Tebano, MT | 1 |
| Nistri, A; Taccola, G | 1 |
| Nagashima, R; Ogita, K; Okuda, H; Sugiyama, C; Watanabe, M; Yoneda, Y | 1 |
| Ferguson, AV; Leveck, DE; Yang, B | 1 |
| Fukuda, S; Hisatsune, T; Namba, T; Seki, T; Tozuka, Y | 1 |
| Hetman, M; Kalita, K; Kharebava, G; Zheng, JJ | 1 |
| Inoue, H; Okada, Y | 1 |
| Smith, AJ; Smith, RA; Stone, TW; Tauskela, JS | 1 |
| Cammarota, M; Carmignoto, G; Chiavegato, A; Gomez-Gonzalo, M; Losi, G | 1 |
| Brondi, M; Cammarota, M; Carmignoto, G; Chiavegato, A; de Curtis, M; Gómez-Gonzalo, M; Losi, G; Pozzan, T; Ratto, GM; Uva, L; Vetri, F; Zonta, M | 1 |
| Coquinco, A; Craig, AM; Cynader, M; Kaufman, AM; Lee, H; Milnerwood, AJ; Raymond, LA; Sepers, MD; She, K; Wang, L | 1 |
| Arizono, M; Bannai, H; Fukatsu, K; Mikoshiba, K; Niwa, F; Triller, A | 1 |
| Burat, I; Dalkilic, N; Tuncer, S | 1 |
| Franke, H; Illes, P; Khan, MT; Liu, J; Nerlich, J; Tang, Y | 1 |
| Chen, K; Fang, H; Gao, S; Hu, S; Sun, X; Wang, H | 1 |
1 review(s) available for 4-aminopyridine and n-methylaspartate
| Article | Year |
|---|---|
Release and uptake of glutamate as related to excitotoxicity.
Topics: 4-Aminopyridine; Cell Culture Techniques; Glutamic Acid; N-Methylaspartate; Nerve Degeneration | 1996 |
44 other study(ies) available for 4-aminopyridine and n-methylaspartate
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
NMDA receptor antagonists protect against seizures and wet-dog shakes induced by 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Amino Acids; Animals; Behavior, Animal; Male; N-Methylaspartate; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Seizures | 1992 |
Glycine and GABA potentiate 4-aminopyridine and/or N-methyl-D-aspartate induced [3H]-noradrenaline release from rat hippocampal slices.
Topics: 4-Aminopyridine; Animals; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Hippocampus; In Vitro Techniques; N-Methylaspartate; Norepinephrine; Rats | 1992 |
Veratridine and other depolarizing agents counteract the inhibitory effect of Mg2+ ions on N-methyl-D-aspartate (NMDA)-induced noradrenaline release in vitro.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Amifampridine; Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Stimulation; Hydrogen; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Veratridine; Veratrine | 1990 |
NMDA-independent form of long-term potentiation produced by tetraethylammonium in the hippocampal CA1 region.
Topics: 4-Aminopyridine; Animals; Aspartic Acid; Calcium Channels; Drug Synergism; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds | 1990 |
Bursting induces persistent all-or-none EPSPs by an NMDA-dependent process in piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cerebral Cortex; Chlorides; In Vitro Techniques; Ketamine; Magnesium; Membrane Potentials; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Time Factors; Valine | 1989 |
Effects of ketamine and (+)cyclazocine on 4-aminopyridine and "magnesium free" epileptogenic activity in hippocampal slices of rats.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cyclazocine; Epilepsy; Hippocampus; Ketamine; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine | 1987 |
Multivesicular release from excitatory synapses of cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Electric Stimulation; Evoked Potentials; Hippocampus; N-Methylaspartate; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Cyclothiazide selectively potentiates AMPA- and kainate-induced [3H]norepinephrine release from rat hippocampal slices.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Drug Synergism; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Tritium; Veratridine | 1994 |
Potassium and calcium channel dependence of bursting in cultured neuronal networks.
Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Apamin; Barium Compounds; Bicuculline; Calcium Channels; Cesium; Charybdotoxin; Chlorides; Choline; Diltiazem; Electrophysiology; Fetus; Magnesium Chloride; Mice; Muscarine; N-Methylaspartate; Nerve Net; Neurons; Organ Culture Techniques; Ouabain; Potassium Channels; Potassium Chloride; Scorpion Venoms; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Veratridine | 1994 |
Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cobalt; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium Channels; Quinoxalines; Rats; Receptors, Amino Acid; Retina; Retinal Ganglion Cells; Sodium Channels; Strychnine; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium; Evoked Potentials; Glucose; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Pipecolic Acids; Pyramidal Tracts; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Tritium | 1993 |
Synchronous potentials and elevations in [K+]o in the adult rat entorhinal cortex maintained in vitro.
Topics: 4-Aminopyridine; Animals; Entorhinal Cortex; Epilepsy; Membrane Potentials; N-Methylaspartate; Potassium; Rats; Rats, Sprague-Dawley | 1995 |
Expression of the neural axon adhesion molecule L1 in the developing and adult rat brain.
Topics: 4-Aminopyridine; Animals; Brain; Cell Adhesion Molecules, Neuronal; Cerebellum; Female; Gene Expression Regulation, Developmental; Glycosylation; Leukocyte L1 Antigen Complex; N-Methylaspartate; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1994 |
Tetrahydroaminoacridine is neurotrophic and promotes the expression of muscarinic receptor-coupled phosphoinositide turnover in differentiating cerebellar granule cells.
Topics: 4-Aminopyridine; Animals; Carbachol; Cell Survival; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Kinetics; N-Methylaspartate; Neurons; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Tacrine | 1993 |
Synchronous GABA-mediated potentials and epileptiform discharges in the rat limbic system in vitro.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Animals; Disease Models, Animal; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Limbic System; Male; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin Receptor Agonists | 1996 |
Reverberation of chloride-dependent synaptic potentials in the rat entorhinal cortex in vitro.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chloride Channels; Chlorides; Electrophysiology; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; N-Methylaspartate; Periodicity; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1996 |
NMDA receptor-mediated increase in cyclic GMP in the rat cerebellum in vivo is blocked by alaproclate and GEA-857.
Topics: 4-Aminopyridine; Alanine; Animals; Behavior, Animal; Cerebellum; Convulsants; Cyclic GMP; Drug Interactions; Harmaline; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Selective Serotonin Reuptake Inhibitors; Valine | 1997 |
Anticonvulsant activity of novel derivatives of 2- and 3-piperidinecarboxylic acid in mice and rats.
Topics: 4-Aminopyridine; Amygdala; Animals; Anticonvulsants; Brain; Convulsants; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Molecular Structure; N-Methylaspartate; Neurotoxins; Nipecotic Acids; Pentylenetetrazole; Pipecolic Acids; Proline; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Seizures; Structure-Activity Relationship; Valproic Acid | 1996 |
[S]-AR-R 15896AR-A novel anticonvulsant: acute safety, pharmacokinetic and pharmacodynamic properties.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Kainic Acid; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Sprague-Dawley; Seizures; Seizures, Febrile; Strychnine; Time Factors; Weaning | 1999 |
Differential effects of potassium channel blockers on the activity of the locomotor network in neonatal rat.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Apamin; Behavior, Animal; Cesium; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Locomotion; Motor Neurons; N-Methylaspartate; Periodicity; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Serotonin; Spinal Cord; Tetraethylammonium | 1999 |
Enhancement of glutamate release uncovers spillover-mediated transmission by N-methyl-D-aspartate receptors in the rat hippocampus.
Topics: 4-Aminopyridine; Animals; Calcium; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; N-Methylaspartate; Osmolar Concentration; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
Interaction between disinhibited bursting and fictive locomotor patterns in the rat isolated spinal cord.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Bicuculline; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Magnesium; Models, Neurological; Motor Activity; Motor Neurons; N-Methylaspartate; Neurons; Potassium; Rats; Rats, Wistar; Serotonin; Spinal Cord; Spinal Nerve Roots; Strychnine | 1999 |
Characterization of a high-voltage-activated IA current with a role in spike timing and locomotor pattern generation.
Topics: 4-Aminopyridine; Action Potentials; Animals; Catechols; Cells, Cultured; Electric Conductivity; Excitatory Amino Acid Agonists; In Vitro Techniques; Lampreys; Motor Activity; Motor Neurons; N-Methylaspartate; Nerve Net; Potassium Channel Blockers; Potassium Channels; Sodium Channels; Spinal Cord; Swimming; Tetraethylammonium; Tetrodotoxin | 2001 |
Presynaptic N-methyl-D-aspartate receptor activation inhibits neurotransmitter release through nitric oxide formation in rat hippocampal nerve terminals.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Radioisotopes; Excitatory Amino Acid Agonists; Exocytosis; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Nitric Oxide; Presynaptic Terminals; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptosomes; Tritium | 2001 |
Slowly inactivating potassium conductance (I(D)): a potential target for stroke therapy.
Topics: 4-Aminopyridine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Death; Cells, Cultured; Electric Conductivity; Excitatory Postsynaptic Potentials; Humans; Hypothalamus; Kinetics; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Stroke | 2001 |
Calcium signaling at single mossy fiber presynaptic terminals in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Calcium Signaling; Coloring Agents; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Indoles; Mossy Fibers, Hippocampal; N-Methylaspartate; Organ Culture Techniques; Potassium Channel Blockers; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Ruthenium Red; Ryanodine; Thapsigargin | 2002 |
Effect of 4-aminopyridine on synaptic transmission in rat hippocampal slices.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Synaptic Transmission; Time Factors | 2004 |
Protective cap over CA1 synapses: extrasynaptic glutamate does not reach the postsynaptic density.
Topics: 4-Aminopyridine; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Dizocilpine Maleate; Drug Interactions; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Models, Neurological; N-Methylaspartate; Neural Inhibition; Neurons; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Synapses | 2004 |
Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum.
Topics: 4-Aminopyridine; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Calcium; Corpus Striatum; Dose-Response Relationship, Drug; Glutamic Acid; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Models, Biological; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Phenethylamines; Pyrimidines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Synaptic Transmission; Triazines; Triazoles | 2004 |
Low micromolar concentrations of 4-aminopyridine facilitate fictive locomotion expressed by the rat spinal cord in vitro.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Locomotion; N-Methylaspartate; Nerve Net; Rats; Rats, Wistar; Spinal Cord | 2004 |
In vivo treatment with the K+ channel blocker 4-aminopyridine protects against kainate-induced neuronal cell death through activation of NMDA receptors in murine hippocampus.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Behavior, Animal; Blotting, Western; Cell Count; Cell Death; Dizocilpine Maleate; DNA, Single-Stranded; Drug Interactions; Endodeoxyribonucleases; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Kainic Acid; Mice; N-Methylaspartate; Neurons; Potassium Channel Blockers; Proto-Oncogene Proteins c-fos; Receptors, N-Methyl-D-Aspartate; Staining and Labeling; Time Factors | 2005 |
Transient potassium conductances protect nucleus tractus solitarius neurons from NMDA induced excitotoxic plateau depolarizations.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 2005 |
GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basic Helix-Loop-Helix Transcription Factors; Bicuculline; Bromodeoxyuridine; Calbindins; Calcium; Cell Count; Cell Differentiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Green Fluorescent Proteins; Hippocampus; History, Ancient; Immunohistochemistry; In Vitro Techniques; Intermediate Filament Proteins; Ki-67 Antigen; Membrane Potentials; Mice; Mice, Transgenic; Microscopy, Immunoelectron; N-Methylaspartate; Nerve Tissue Proteins; Nestin; Neural Cell Adhesion Molecule L1; Neurons; Nickel; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Potassium Channel Blockers; S100 Calcium Binding Protein G; Sialic Acids; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Stem Cells; Tetrodotoxin; Vesicular Inhibitory Amino Acid Transport Proteins | 2005 |
Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity.
Topics: 4-Aminopyridine; Amides; Animals; Animals, Newborn; Bicuculline; Brain-Derived Neurotrophic Factor; Butadienes; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Chromones; COS Cells; Cysteine-Rich Protein 61; Gene Expression Regulation; Genes, fos; Hippocampus; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; N-Methylaspartate; Neurons; Nitriles; Potassium Chloride; Prosencephalon; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; RNA Interference; Serum Response Factor; Signal Transduction; Synaptic Transmission; Transcription Factors; Transcription, Genetic; Transfection | 2006 |
Roles of volume-sensitive chloride channel in excitotoxic neuronal injury.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Apoptosis; Benzothiadiazines; Bicuculline; Bumetanide; Cell Size; Cells, Cultured; Cerebral Cortex; Chlorides; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glycolates; Ion Channels; Mice; Mice, Inbred C57BL; N-Methylaspartate; Necrosis; Neurons; Neurotoxins; Nitrobenzoates; Patch-Clamp Techniques; Phloretin; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Quinine; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Sodium Chloride Symporters; Somatosensory Cortex; Tetrodotoxin | 2007 |
Preconditioning with 4-aminopyridine protects cerebellar granule neurons against excitotoxicity.
Topics: 4-Aminopyridine; Animals; Bicuculline; Cell Death; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
A new experimental model of focal seizures in the entorhinal cortex.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Calcium; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Agonists; In Vitro Techniques; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar | 2010 |
An excitatory loop with astrocytes contributes to drive neurons to seizure threshold.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Chelating Agents; Egtazic Acid; Entorhinal Cortex; Excitatory Amino Acid Agonists; Glutamic Acid; Guinea Pigs; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Seizures | 2010 |
Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Bicuculline; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Corpus Striatum; CREB-Binding Protein; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agents; Female; GABA-A Receptor Antagonists; Glutamate Decarboxylase; Glycine Agents; Luminescent Proteins; Microfluidic Analytical Techniques; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nifedipine; Patch-Clamp Techniques; Potassium Channel Blockers; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium Channel Blockers; Strychnine; Synapses; Tetrodotoxin; Transfection; Vesicular Glutamate Transport Protein 1 | 2012 |
Gephyrin-independent GABA(A)R mobility and clustering during plasticity.
Topics: 4-Aminopyridine; Animals; Astrocytes; Carrier Proteins; Cells, Cultured; Cluster Analysis; HeLa Cells; Hippocampus; Humans; Immunohistochemistry; Membrane Proteins; N-Methylaspartate; Quantum Dots; Rats; Rats, Wistar; Receptors, GABA-A; Synapses | 2012 |
Electrophysiological alterations in diaphragm muscle caused by abdominal ischemia-reperfusion.
Topics: 4-Aminopyridine; Action Potentials; Analysis of Variance; Animals; Biophysics; Diaphragm; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agonists; Ischemia; Male; Muscle Contraction; N-Methylaspartate; Potassium Channel Blockers; Rats; Rats, Wistar; Reperfusion Injury; Ryanodine; Time Factors | 2017 |
Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dentate Gyrus; Female; Gabapentin; Male; Mice; Muscimol; N-Methylaspartate; Neural Stem Cells; Neurons; Phenytoin; Receptors, Purinergic P2X7; Tetrodotoxin; Valproic Acid | 2018 |
Long Noncoding RNA Expression Profiles of Rat Extrasynaptic and Synaptic Neurons Expressing the N-methyl-D-Aspartate Receptor Revealed by Microarray Analysis.
Topics: 4-Aminopyridine; Animals; Bicuculline; Cerebral Cortex; Down-Regulation; Excitatory Amino Acid Agonists; GABA-A Receptor Antagonists; Glycine; Glycine Agents; Microarray Analysis; N-Methylaspartate; Neurons; Polymerase Chain Reaction; Potassium Channel Blockers; Primary Cell Culture; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Long Noncoding; Synapses; Up-Regulation | 2021 |