4-aminopyridine has been researched along with morphine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (40.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Fredholm, BB | 1 |
| Houston, T; Pleuvry, BJ | 1 |
| Mulder, AH; Schoffelmeer, AN | 2 |
| Casamenti, F; Corradetti, R; Löffelholz, K; Mantovani, P; Pepeu, G | 1 |
| Crain, B; Crain, SM; Peterson, ER | 1 |
| Stone, TW | 1 |
| Sia, RL; Zandstra, DF | 1 |
| Elliott, JM; Grahame-Smith, DG; Pei, Q; Zetterström, T | 1 |
| Bills, D; Ghosh, S; Grasing, K; Patel, AH; Schlussman, SD; Woodward, JJ | 1 |
| Cousins, M; Ghosh, S; Grasing, K; Patel, AH | 1 |
| Kankaanpää, A; Lillsunde, P; Meririnne, E; Seppälä, T; Vanakoski, J | 1 |
| Duarte, ID; Rodrigues, AR | 1 |
| Hata, F; Nishio, H; Nishiwaki, H; Saitoh, N; Takeuch, T | 1 |
| Enginar, N; Kara , I; Koyuncuoğlu, H; Nurten, A; Ozerman, B | 1 |
| Castañeda-Hernández, G; Granados-Soto, V; Ortiz, MI; Rosas, R; Torres-López, JE; Vidal-Cantú, GC | 1 |
| Argüelles, CF; Granados-Soto, V; Ortiz, MI | 1 |
| Hung, CF; Lee, YJ; Su, MJ; Wang, SJ; Yang, TT | 1 |
| Alloui, A; Boudes, M; Bourinet, E; Chemin, J; Eschalier, A; François, A; Kerckhove, N; Mallet, C; Voets, T | 1 |
20 other study(ies) available for 4-aminopyridine and morphine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Differential sensitivity to blockade by 4-aminopyridine of presynaptic receptors regulating [3H]acetylcholine release from rat hippocampus.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Cadmium; Cadmium Chloride; Calcium Channel Blockers; Carbachol; Hippocampus; Male; Mollusk Venoms; Morphine; omega-Conotoxin GVIA; Osmolar Concentration; Phenylisopropyladenosine; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Tritium | 1990 |
Comparison of some pharmacological properties of 4-aminopyridine and 3,4-diaminopyridine in vivo.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Central Nervous System Stimulants; Depression, Chemical; Drug Interactions; Mice; Morphine; Respiration | 1984 |
Presynaptic alpha-adrenoceptors and opiate receptors: inhibition of [3H]noradrenaline release from rat cerebral cortex slices by different mechanisms.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cerebral Cortex; Electric Stimulation; In Vitro Techniques; Male; Morphine; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid | 1982 |
Differential control of Ca2+-dependent [3H]noradrenaline release from rat brain slices through presynaptic opiate receptors and alpha-adrenoceptors.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Brain; Cadmium; Calcium; Cell Membrane Permeability; Electric Stimulation; Electrolytes; In Vitro Techniques; Male; Morphine; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid; Tritium | 1983 |
Effects of 4-aminopyridine on acetylcholine output from the cerebral cortex of the rat in vivo.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Anesthesia; Animals; Blood Pressure; Cerebral Cortex; Male; Morphine; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains | 1982 |
Development of cross-tolerance to 5-hydroxytryptamine in organotypic cultures of mouse spinal cord-ganglia during chronic exposure to morphine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Drug Tolerance; Ganglia, Spinal; Mice; Morphine; Naloxone; Organ Culture Techniques; Serotonin; Spinal Cord | 1982 |
The effects of 4-aminopyridine on the isolated vas deferens and its effects on the inhibitory properties of adenosine, morphine, noradrenaline and gamma-aminobutyric acid.
Topics: 4-Aminopyridine; Adenosine; Aminopyridines; Animals; Calcium; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Morphine; Muscle Contraction; Neuromuscular Depolarizing Agents; Norepinephrine; Potassium Chloride; Quinidine; Tetraethylammonium Compounds; Vas Deferens | 1981 |
Use of 4-aminopyridine to reverse morphine-induced respiratory depression in man.
Topics: 4-Aminopyridine; Adolescent; Adult; Aminopyridines; Anesthesia, Intravenous; Depression, Chemical; Female; Humans; Male; Middle Aged; Morphine; Respiration; Respiratory Insufficiency; Tidal Volume | 1981 |
Quinine and 4-aminopyridine inhibit the stimulatory output of dopamine in nucleus accumbens and the behavioural activity produced by morphine.
Topics: 4-Aminopyridine; Analgesics; Animals; Behavior, Animal; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Male; Microdialysis; Morphine; Nucleus Accumbens; Potassium Channels; Quinine; Rats; Rats, Sprague-Dawley | 1993 |
Opiate modulation of striatal dopamine and hippocampal norepinephrine release following morphine withdrawal.
Topics: 4-Aminopyridine; Analgesics, Opioid; Animals; Calcium; Corpus Striatum; Drug Evaluation, Preclinical; Hippocampus; In Vitro Techniques; Male; Morphine; Norepinephrine; Potassium; Rats; Rats, Wistar; Stimulation, Chemical; Substance Withdrawal Syndrome | 1997 |
Different effects of opiate withdrawal on dopamine turnover, uptake, and release in the striatum and nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Aminopyridine; Animals; Corpus Striatum; Dopamine; Male; Morphine; Narcotics; Nucleus Accumbens; Potassium; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Time Factors | 1998 |
The effects of quinine and 4-aminopyridine on conditioned place preference and changes in motor activity induced by morphine in rats.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Conditioning, Operant; Male; Morphine; Motor Activity; Potassium Channel Blockers; Quinine; Rats; Rats, Wistar | 1999 |
The peripheral antinociceptive effect induced by morphine is associated with ATP-sensitive K(+) channels.
Topics: 4-Aminopyridine; Analgesics, Opioid; Animals; Apamin; ATP-Binding Cassette Transporters; Cesium; Charybdotoxin; Drug Interactions; Hyperalgesia; Hypoglycemic Agents; KATP Channels; Large-Conductance Calcium-Activated Potassium Channels; Male; Morphine; Pain Measurement; Peripheral Nerves; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Tetraethylammonium | 2000 |
Possible role of potassium channels in mu-receptor-mediated inhibition and muscarinic autoinhibition in acetylcholine release from myenteric plexus of guinea pig ileum.
Topics: 4-Aminopyridine; Acetylcholine; Analgesics, Opioid; Animals; Apamin; Atropine; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Glyburide; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscarinic Antagonists; Myenteric Plexus; Naloxone; Narcotic Antagonists; Neuromuscular Junction; Peptides; Potassium Channel Blockers; Potassium Channels; Receptors, Muscarinic; Receptors, Opioid, mu; Tetraethylammonium | 2000 |
The effects of different 4-aminopyridine and morphine combinations on the intensity of morphine abstinence.
Topics: 4-Aminopyridine; Animals; Behavior, Animal; Calcium; Disease Models, Animal; Glutamic Acid; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2001 |
Pharmacological evidence for the activation of K(+) channels by diclofenac.
Topics: 4-Aminopyridine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship, Drug; Female; Formaldehyde; Glyburide; Hindlimb; Morphine; Pain; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Tetraethylammonium; Tolbutamide | 2002 |
The peripheral antinociceptive effect of resveratrol is associated with activation of potassium channels.
Topics: 4-Aminopyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; ATP-Binding Cassette Transporters; Charybdotoxin; Female; Glipizide; Glyburide; KATP Channels; Morphine; Narcotics; Peripheral Nervous System; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tetraethylammonium; Tolbutamide | 2002 |
Morphine inhibits glutamate exocytosis from rat cerebral cortex nerve terminals (synaptosomes) by reducing Ca2+ influx.
Topics: 4-Aminopyridine; Analgesics, Opioid; Animals; Benzothiazoles; Benzoxazines; Calcium; Calcium Channel Blockers; Carbocyanines; Cerebral Cortex; Dose-Response Relationship, Drug; Exocytosis; Fluorometry; Fura-2; Glutamic Acid; Ionomycin; Ionophores; Male; Membrane Potentials; Morphine; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Synaptosomes | 2004 |
Ca(v)3.2 calcium channels: the key protagonist in the supraspinal effect of paracetamol.
Topics: 4-Aminopyridine; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Arthritis; Calcium Channels, T-Type; Cells, Cultured; Drug Administration Routes; Drug Interactions; Ganglia, Spinal; Humans; Male; Membrane Potentials; Mice; Mice, Knockout; Morphine; Neurons; Pain Measurement; Potassium Channel Blockers; Spinal Cord; Tetraethylammonium; TRPV Cation Channels | 2014 |