4-aminopyridine has been researched along with lamotrigine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (66.67) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Cahill, CM; Coderre, TJ; Fisher, K; Lefebvre, C | 1 |
| Gean, PW; Sihra, TS; Wang, SJ | 1 |
| Avoli, M; D'Arcangelo, G; Tancredi, V | 1 |
| Avoli, M; D'Antuono, M; D'Arcangelo, G; Longone, P; Manfredi, M; Tancredi, V; Zona, C | 1 |
| Baraban, SC; Barbaro, NM; Smyth, MD | 1 |
| Armijo, JA; Bravo, J; Cuadrado, A | 1 |
| Bernardi, G; Bonsi, P; Calabresi, P; Costa, C; De Persis, C; Martella, G; Pisani, A; Pisani, F | 1 |
| Huang, CC; Huang, CW; Liu, YC; Wu, SN | 1 |
| Bozdemir, H; Gunay, I; Guven, M; Kahraman, I; Koc, F; Sarica, Y | 2 |
| He, XH; Justice, JA; Peng, BW; Sanchez, RM; Zhang, K | 1 |
| Aldana, BI; Chiu, LM; Guarneros, A; Sanchez-Tafolla, BM; Sitges, M | 1 |
| Cao, Z; Cui, Y; Hulsizer, S; Lein, PJ; Pessah, IN; Wulff, H; Zou, X | 1 |
15 other study(ies) available for 4-aminopyridine and lamotrigine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Evidence that DHPG-induced nociception depends on glutamate release from primary afferent C-fibres.
Topics: 4-Aminopyridine; Animals; Behavior, Animal; Capsaicin; Excitatory Amino Acid Agonists; Glutamic Acid; Injections, Spinal; Lamotrigine; Male; Methoxyhydroxyphenylglycol; Nerve Fibers; Neurons, Afferent; Nociceptors; Proline; Propionates; Rats; Rats, Long-Evans; Riluzole; Triazines | 2000 |
Lamotrigine inhibition of glutamate release from isolated cerebrocortical nerve terminals (synaptosomes) by suppression of voltage-activated calcium channel activity.
Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Excitatory Amino Acid Antagonists; Glutamic Acid; Lamotrigine; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley; Synaptosomes; Triazines | 2001 |
Intrinsic optical signals and electrographic seizures in the rat limbic system.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Axotomy; Electric Stimulation; Electroencephalography; Electrophysiology; Entorhinal Cortex; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Fructose; GABA Antagonists; Hippocampus; Lamotrigine; Neurons; Optics and Photonics; Organ Culture Techniques; Perforant Pathway; Potassium Channel Blockers; Rats; Rats, Wistar; Reaction Time; Seizures; Signal Processing, Computer-Assisted; Synaptic Transmission; Topiramate; Triazines | 2001 |
Neocortical potassium currents are enhanced by the antiepileptic drug lamotrigine.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; In Vitro Techniques; Lamotrigine; Neocortex; Potassium Channels; Rats; Rats, Wistar; Triazines | 2002 |
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Disease Models, Animal; Electroencephalography; Epilepsy; Ethosuximide; Female; Hippocampus; In Vitro Techniques; Lamotrigine; Methylazoxymethanol Acetate; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazines; Valproic Acid | 2002 |
Synergistic interaction between felbamate and lamotrigine against seizures induced by 4-aminopyridine and pentylenetetrazole in mice.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Drug Synergism; Felbamate; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Lamotrigine; Mice; Pentylenetetrazole; Phenylcarbamates; Potassium Channel Blockers; Propylene Glycols; Rats; Seizures; Triazines | 2003 |
Intracellular calcium increase in epileptiform activity: modulation by levetiracetam and lamotrigine.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Epilepsy; Lamotrigine; Levetiracetam; Male; Membrane Potentials; Neocortex; Patch-Clamp Techniques; Piracetam; Pyramidal Cells; Rats; Rats, Wistar; Triazines | 2004 |
Inhibitory effect of lamotrigine on A-type potassium current in hippocampal neuron-derived H19-7 cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Capsaicin; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Hippocampus; Lamotrigine; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Rats; Rats, Sprague-Dawley; Triazines | 2004 |
The actions of lamotrigine and levetiracetam on the conduction properties of isolated rat sciatic nerve.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electrophysiology; Female; In Vitro Techniques; Lamotrigine; Levetiracetam; Neural Conduction; Patch-Clamp Techniques; Piracetam; Potassium Channel Blockers; Rats; Rats, Wistar; Sciatic Nerve; Triazines | 2006 |
Increased basal synaptic inhibition of hippocampal area CA1 pyramidal neurons by an antiepileptic drug that enhances I(H).
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Biophysics; CA1 Region, Hippocampal; Cadmium Chloride; Calcium Channel Blockers; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Lamotrigine; Lysine; Male; Neural Inhibition; Patch-Clamp Techniques; Potassium Channel Blockers; Pyramidal Cells; Quinoxalines; Rats; Rats, Long-Evans; Tetraethylammonium; Triazines; Valine | 2010 |
The conduction block produced by oxcarbazepine in the isolated rat sciatic nerve: a comparison with lamotrigine.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Electric Stimulation; Female; Lamotrigine; Neural Conduction; Oxcarbazepine; Rats; Rats, Wistar; Sciatic Nerve; Triazines | 2011 |
Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Calcium; Carbamazepine; Drug Interactions; Epilepsy; Fructose; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Lamotrigine; Male; Nerve Endings; Oxcarbazepine; Phenytoin; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetrodotoxin; Topiramate; Triazines; Tritium; Vinca Alkaloids | 2011 |
Rapid throughput analysis demonstrates that chemicals with distinct seizurogenic mechanisms differentially alter Ca2+ dynamics in networks formed by hippocampal neurons in culture.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Calcium; Cells, Cultured; High-Throughput Screening Assays; Hippocampus; Kainic Acid; Lamotrigine; Mice, Inbred C57BL; Muscarinic Agonists; Nerve Net; Neurons; Potassium Channel Blockers; Receptors, Kainic Acid; Seizures; Triazines | 2015 |