4-aminopyridine has been researched along with flecainide in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (50.00) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aiyar, J; Auperin, DD; Chandy, KG; Grissmer, S; Gutman, GA; Hanson, DC; Karmilowicz, MJ; Mather, RJ; Nguyen, AN | 1 |
| Sen, S; Sinha, N | 1 |
| Al-Sabi, A; Daly, D; Dolly, JO; Herron, C; Hoefer, P; Kaza, SK; Kinsella, GK; Metais, C; Nolan, K; Pickering, M | 1 |
| Antzelevitch, C; Di Diego, JM; Gintant, GA; Krishnan, SC; Litovsky, SH; Liu, DW; Lukas, A; Sicouri, S | 1 |
| Guize, L; Hatem, S; Lavergne, T; Le Grand, B; Le Heuzey, JY; Perier, P; Peronneau, P | 1 |
| Hamada, E; Hazama, H; Kurachi, Y; Nakajima, T; Omata, M; Yamashita, T | 1 |
| Fermini, B; Nattel, S; Wang, Z | 1 |
| Antzelevitch, C; Krishnan, SC | 1 |
| Kubota, I; Tachibana, H; Tomoike, H; Watanabe, T; Yamaki, M; Yamauchi, S | 1 |
| Hancox, JC; Mitcheson, JS | 1 |
| Boyett, MR; Honjo, H; Kodama, I; Lei, M | 1 |
| Ikeda, M; Ito, M; Matsumoto, S; Nishikawa, T; Saiki, C; Takeda, M; Tanimoto, T; Yoshida, S | 1 |
| Sacco, T; Tempia, F | 1 |
| Amberg, GC; Baker, SA; Hatton, WJ; Horowitz, B; Koh, SD; Murray, KJ; Sanders, KM | 1 |
| Coutu, P; Dittrich, W; Ehrlich, JR; Gögelein, H; Hoche, C; Hohnloser, SH; Metz-Weidmann, C; Nattel, S | 1 |
| Walsh, KB; Zhang, J | 1 |
1 review(s) available for 4-aminopyridine and flecainide
| Article | Year |
|---|---|
Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells.
Topics: 4-Aminopyridine; Action Potentials; Age Factors; Amiloride; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Coronary Disease; Dogs; Electric Conductivity; Endocardium; Flecainide; Heart Ventricles; Hot Temperature; Humans; In Vitro Techniques; Parasympathomimetics; Sodium Channels; Sympathomimetics; Ventricular Function | 1991 |
15 other study(ies) available for 4-aminopyridine and flecainide
| Article | Year |
|---|---|
Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
Topics: 3T3 Cells; Animals; Base Sequence; Benzopyrans; Capsaicin; Cell Line; Cells, Cultured; Charybdotoxin; Cloning, Molecular; Cromakalim; Diltiazem; Diterpenes; Elapid Venoms; Flecainide; Ion Channel Gating; Mice; Molecular Sequence Data; Nifedipine; Oligodeoxyribonucleotides; Peptides; Potassium Channels; Pyrroles; Scorpion Venoms; Sotalol | 1994 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
A Rational Design of a Selective Inhibitor for Kv1.1 Channels Prevalent in Demyelinated Nerves That Improves Their Impaired Axonal Conduction.
Topics: Animals; Cell Line; Corpus Callosum; Demyelinating Diseases; Drug Design; Humans; Kv1.1 Potassium Channel; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Potassium Channel Blockers; Pyrroles | 2017 |
Cellular electrophysiological effects of flecainide on human atrial fibres.
Topics: 4-Aminopyridine; Action Potentials; Adolescent; Adult; Aged; Child; Child, Preschool; Dose-Response Relationship, Drug; Electric Stimulation; Flecainide; Heart; Heart Atria; Humans; In Vitro Techniques; Middle Aged; Time Factors | 1990 |
Flecainide inhibits the transient outward current in atrial myocytes isolated from the rabbit heart.
Topics: 4-Aminopyridine; Action Potentials; Animals; Atrial Function; Flecainide; Heart Atria; In Vitro Techniques; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Rabbits | 1995 |
Effects of flecainide, quinidine, and 4-aminopyridine on transient outward and ultrarapid delayed rectifier currents in human atrial myocytes.
Topics: 4-Aminopyridine; Dose-Response Relationship, Drug; Flecainide; Heart Atria; Humans; In Vitro Techniques; Ion Channel Gating; Middle Aged; Potassium; Potassium Channels; Quinidine | 1995 |
Flecainide-induced arrhythmia in canine ventricular epicardium. Phase 2 reentry?
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Dogs; Endocardium; Flecainide; Heart Ventricles; Male; Models, Cardiovascular; Osmolar Concentration; Pericardium; Reaction Time | 1993 |
Intracoronary flecainide induces ST alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyramide; Dogs; Electrocardiography; Flecainide; Injections; Lidocaine; Piperidines; Pyridines; Sodium Channels; Ventricular Fibrillation; Verapamil | 1999 |
Characteristics of a transient outward current (sensitive to 4-aminopyridine) in Ca2+-tolerant myocytes isolated from the rabbit atrioventricular node.
Topics: 4-Aminopyridine; Action Potentials; Algorithms; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Electrophysiology; Flecainide; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Quinidine; Rabbits | 1999 |
Characterisation of the transient outward K+ current in rabbit sinoatrial node cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Cell Size; Flecainide; Linear Models; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Quinidine; Rabbits; Sinoatrial Node | 2000 |
Excitatory mechanism of deflationary slowly adapting pulmonary stretch receptors in the rat lung.
Topics: 4-Aminopyridine; Anesthesia; Animals; Anti-Arrhythmia Agents; Flecainide; Injections, Intravenous; Lung; Myelin Sheath; Nerve Fibers, Myelinated; Potassium Channel Blockers; Potassium Channels; Pulmonary Stretch Receptors; Rats; Rats, Wistar; Respiration, Artificial; Sciatic Nerve; Tetraethylammonium; Vagotomy; Veratridine | 2002 |
A-type potassium currents active at subthreshold potentials in mouse cerebellar Purkinje cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Dendrites; Female; Flecainide; Male; Mice; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Purkinje Cells; Scorpion Venoms; Tetraethylammonium | 2002 |
Characterization of the A-type potassium current in murine gastric antrum.
Topics: 4-Aminopyridine; Animals; Electric Conductivity; Flecainide; Membrane Potentials; Mice; Mice, Inbred BALB C; Muscle, Smooth; Myocytes, Smooth Muscle; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Isoforms; Pyloric Antrum; Shal Potassium Channels; Tetraethylammonium | 2002 |
Properties of a time-dependent potassium current in pig atrium: evidence for a role of kv1.5 in repolarization.
Topics: 4-Aminopyridine; Action Potentials; Animals; Chlorides; Flecainide; Heart Atria; Kv1.5 Potassium Channel; Male; Neurotoxins; Perhexiline; Potassium; Reverse Transcriptase Polymerase Chain Reaction; Swine; Time Factors | 2006 |
Neonatal rat cardiac fibroblasts express three types of voltage-gated K+ channels: regulation of a transient outward current by protein kinase C.
Topics: 4-Aminopyridine; Angiotensin II; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Blotting, Western; Calcium; Calcium Signaling; Electrophysiology; Fibroblasts; Flecainide; Heart; Myocardium; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate | 2008 |