4-aminopyridine has been researched along with diltiazem in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (34.78) | 18.7374 |
| 1990's | 10 (43.48) | 18.2507 |
| 2000's | 4 (17.39) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Aiyar, J; Auperin, DD; Chandy, KG; Grissmer, S; Gutman, GA; Hanson, DC; Karmilowicz, MJ; Mather, RJ; Nguyen, AN | 1 |
| Brandriff, B; Cahalan, M; Chandy, G; Chandy, KG; Copeland, NG; Dukes, ID; Gutman, GA; Hustad, CM; Jenkins, NA; Kalman, K; Mohrenweiser, H; Nguyen, A; Tseng-Crank, J | 1 |
| Al-Sabi, A; Daly, D; Dolly, JO; Herron, C; Hoefer, P; Kaza, SK; Kinsella, GK; Metais, C; Nolan, K; Pickering, M | 1 |
| Brent, LH; Bubien, JK; Butler, JL; Woods, WT | 1 |
| Chou, SM; Gean, PW | 1 |
| Dreyer, F; Penner, R | 1 |
| Matsumoto, M; Riker, WK; Takashima, K | 1 |
| Kato, H; Takata, Y | 1 |
| Mustafa, SJ; Nakazawa, M | 1 |
| Hotta, K; Oba, T | 1 |
| Cahalan, MD; Chandy, KG; DeCoursey, TE; Gupta, S; McLaughlin, C | 1 |
| Fujiwara, S; Kuriyama, H | 1 |
| Gross, GW; Rhoades, BK | 1 |
| Earm, YE; Ho, WK; So, I | 1 |
| Huizinga, JD; Molleman, A; Thuneberg, L | 1 |
| Gotow, T; Murakami, M; Nishi, T | 1 |
| Katusic, ZS; Onoue, H | 1 |
| Carvajal, A; Dueñas, A; Fernández de la Gándara, F; Maroto, M; Nieto, A; Velasco, A | 1 |
| Imai, T; Koike, K; Okamoto, T; Shigenobu, K; Tanaka, H; Tanaka, Y; Yamamoto, Y | 1 |
| Flameng, W; Macianskiene, R; Moccia, F; Mubagwa, K; Sipido, KR | 1 |
| Fiszer, M; Kołaciński, Z; Rechciński, T | 1 |
| Bonev, AD; Goecks, T; Gokina, NI; Osol, G; Telezhkin, V | 1 |
23 other study(ies) available for 4-aminopyridine and diltiazem
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
Topics: 3T3 Cells; Animals; Base Sequence; Benzopyrans; Capsaicin; Cell Line; Cells, Cultured; Charybdotoxin; Cloning, Molecular; Cromakalim; Diltiazem; Diterpenes; Elapid Venoms; Flecainide; Ion Channel Gating; Mice; Molecular Sequence Data; Nifedipine; Oligodeoxyribonucleotides; Peptides; Potassium Channels; Pyrroles; Scorpion Venoms; Sotalol | 1994 |
Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; Chromosomes; Cloning, Molecular; Electrophysiology; Humans; In Situ Hybridization; Ion Channel Gating; Islets of Langerhans; Mice; Mice, Inbred Strains; Molecular Sequence Data; Neurotoxins; Phylogeny; Potassium Channels; Sequence Analysis, DNA; Shaker Superfamily of Potassium Channels | 1998 |
A Rational Design of a Selective Inhibitor for Kv1.1 Channels Prevalent in Demyelinated Nerves That Improves Their Impaired Axonal Conduction.
Topics: Animals; Cell Line; Corpus Callosum; Demyelinating Diseases; Drug Design; Humans; Kv1.1 Potassium Channel; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Potassium Channel Blockers; Pyrroles | 2017 |
Transmembrane ion conductance in human B lymphocyte activation.
Topics: 4-Aminopyridine; B-Lymphocytes; Calcimycin; Calcium; Cell Cycle; Diltiazem; Electric Conductivity; Humans; Immunoglobulin mu-Chains; In Vitro Techniques; Ion Channels; Lymphocyte Activation; Membrane Potentials; Potassium Channels; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Tetraethylammonium Compounds; Verapamil | 1990 |
Suppression of 4-aminopyridine-induced paroxysmal depolarizing shift in rat amygdaloid neurons by diltiazem.
Topics: 4-Aminopyridine; Amygdala; Animals; Diltiazem; Electrophysiology; In Vitro Techniques; Male; Neurons; Perfusion; Rats; Rats, Inbred Strains | 1991 |
Two different presynaptic calcium currents in mouse motor nerve terminals.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Barium; Cadmium; Calcium; Diltiazem; In Vitro Techniques; Ion Channels; Kinetics; Manganese; Mice; Motor Neurons; Neuromuscular Junction; Potassium; Strontium; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil | 1986 |
Synaptic facilitation by 3-aminopyridine and its antagonism by verapamil and diltiazem.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Benzazepines; Calcium; Diltiazem; Dose-Response Relationship, Drug; Rana catesbeiana; Synapses; Synaptic Transmission; Verapamil | 1985 |
Differential effects of Ca antagonists on the noradrenaline release and contraction evoked by nerve stimulation in the presence of 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Norepinephrine; Salicylates; Salicylic Acid; Stereoisomerism; Tetracaine; Tetrodotoxin; Verapamil | 1987 |
Effects of adenosine and calcium entry blockers on 3,4-diaminopyridine-induced rhythmic contractions in dog coronary artery.
Topics: 4-Aminopyridine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amifampridine; Aminopyridines; Animals; Calcium Channel Blockers; Diltiazem; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Phenylisopropyladenosine | 1988 |
Effects of extracellular calcium and calcium channel blocker on silver-induced contractures in frog skeletal muscle fibers.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Drug Interactions; Morpholines; Muscle Contraction; Rana catesbeiana; Silver; Solutions; Tetrodotoxin | 1987 |
Voltage-gated potassium channels are required for human T lymphocyte activation.
Topics: 4-Aminopyridine; Aminopyridines; Cell Line; Diltiazem; Electrophoresis, Polyacrylamide Gel; Humans; Interleukin-2; Ion Channels; Kinetics; Leucine; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Phytohemagglutinins; Potassium; Protein Biosynthesis; T-Lymphocytes; Thymidine; Verapamil | 1984 |
Effects of agents that modulate potassium permeability on smooth muscle cells of the guinea-pig basilar artery.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Basilar Artery; Caffeine; Diltiazem; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Permeability; Potassium; Procaine; Tetraethylammonium; Tetraethylammonium Compounds | 1983 |
Potassium and calcium channel dependence of bursting in cultured neuronal networks.
Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Apamin; Barium Compounds; Bicuculline; Calcium Channels; Cesium; Charybdotoxin; Chlorides; Choline; Diltiazem; Electrophysiology; Fetus; Magnesium Chloride; Mice; Muscarine; N-Methylaspartate; Nerve Net; Neurons; Organ Culture Techniques; Ouabain; Potassium Channels; Potassium Chloride; Scorpion Venoms; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Veratridine | 1994 |
Effects of adriamycin on ionic currents in single cardiac myocytes of the rabbit.
Topics: 4-Aminopyridine; Animals; Calcium; Diltiazem; Doxorubicin; Heart; In Vitro Techniques; Ion Transport; Membrane Potentials; Myocardium; Ouabain; Rabbits; Sarcoplasmic Reticulum; Sodium | 1994 |
Characterization of the outward rectifying potassium channel in a novel mouse intestinal smooth muscle cell preparation.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Barium; Diltiazem; Electrophysiology; Female; In Vitro Techniques; Intestines; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Models, Biological; Muscle, Smooth; Neuromuscular Depolarizing Agents; Potassium Channels | 1993 |
4-aminopyridine and l-cis-diltiazem block the cGMP-activated K+ channels closed by light in the molluscan extra-ocular photoreceptors.
Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Cyclic GMP; Diltiazem; Ganglia, Invertebrate; Light; Membrane Potentials; Mollusca; Neurons; Photoreceptor Cells, Invertebrate; Potassium Channels | 1997 |
Role of potassium channels in relaxations of canine middle cerebral arteries induced by nitric oxide donors.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; 4-Aminopyridine; Animals; Barium Compounds; Cerebral Arteries; Charybdotoxin; Chlorides; Cyclic GMP; Diltiazem; Dogs; Glyburide; In Vitro Techniques; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Potassium Channels; Purinones; Vasodilation; Vasodilator Agents | 1997 |
Effect of 4-aminopyridine and 3,4-diaminopyridine on guinea-pig isolated ileum.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Animals; Atropine; Calcium Channel Blockers; Diazoxide; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Female; Flunarizine; Guinea Pigs; Ileum; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Parasympathetic Nervous System; Parasympatholytics; Potassium Channels; Vasodilator Agents; Verapamil | 1997 |
Effects of different types of K+ channel modulators on the spontaneous myogenic contraction of guinea-pig urinary bladder smooth muscle.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Apamin; Barium; Benzimidazoles; Calcium Channel Blockers; Cation Transport Proteins; Cromakalim; Diltiazem; Ether-A-Go-Go Potassium Channels; Female; Glyburide; Guinea Pigs; Large-Conductance Calcium-Activated Potassium Channels; Male; Muscle Contraction; Muscle, Smooth; Nisoldipine; Parasympatholytics; Peptides; Periodicity; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Pyridines; Small-Conductance Calcium-Activated Potassium Channels; Urinary Bladder | 2001 |
Channels involved in transient currents unmasked by removal of extracellular calcium in cardiac cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cesium; Chelating Agents; Diltiazem; Drug Resistance; Egtazic Acid; Electric Conductivity; Heart Ventricles; Isoproterenol; Kinetics; Magnesium; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Receptors, Adrenergic, beta; Swine; Verapamil | 2002 |
[The application of 4-aminopyridine in calcium channel inhibitors acute poisoning].
Topics: 4-Aminopyridine; Acute Disease; Adrenergic beta-Antagonists; Adult; Antidotes; Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Drug Overdose; Drug Therapy, Combination; Epinephrine; Female; Heart Rate; Humans; Hypotension; Myocardial Ischemia; Poisoning; Potassium Channel Blockers; Suicide, Attempted; Tachycardia, Supraventricular; Treatment Outcome; Vasoconstrictor Agents; Verapamil | 2007 |
Decreased function of voltage-gated potassium channels contributes to augmented myogenic tone of uterine arteries in late pregnancy.
Topics: 4-Aminopyridine; Animals; Arteries; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Delayed Rectifier Potassium Channels; Diltiazem; Female; Gestational Age; Ion Channel Gating; Membrane Potentials; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pregnancy; Pressure; Rats; Rats, Sprague-Dawley; Uterus; Vasoconstriction; Vasodilator Agents | 2008 |