4-aminopyridine has been researched along with charybdotoxin in 139 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (4.32) | 18.7374 |
| 1990's | 77 (55.40) | 18.2507 |
| 2000's | 51 (36.69) | 29.6817 |
| 2010's | 5 (3.60) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Purali, N; Rydqvist, B | 1 |
| Escobar, L; Martin, BM; Possani, LD; Valdivia, HH | 1 |
| Cahalan, MD; Grissmer, S; Lewis, RS | 1 |
| Cannon, SD; Walsh, KB; Wuthier, RE | 1 |
| Gelband, CH; Hume, JR | 1 |
| Honda, H; Ishida, Y; Watanabe, TX | 1 |
| Barrett, EF; Morita, K | 1 |
| Ferrus, A; Müller, R; Pongs, O; Stocker, M; Stühmer, W; Wang, X; Wittka, R | 1 |
| Lazdunski, M; Schaeffer, P | 1 |
| Haj-Dahmane, S; Hamon, M; Lanfumey, L | 1 |
| Storm, JF | 1 |
| Aldrich, RW; Hoshi, T | 1 |
| Baskin, EP; Garcia, ML; Heaney, LA; Kaczorowski, GJ; Stein, RB; Wallace, AA; Winquist, RJ | 1 |
| Anderson, AJ; Harvey, AL; Rowan, EG; Strong, PN | 1 |
| Davidson, N; Jayashree-Aiyar, S; Karschin, A; Leonard, RJ; Lester, HA; Tanouye, MA; Thomas, G; Thomas, L | 1 |
| Deutsch, C; Lee, SC; Price, M | 1 |
| Lang, RJ; Zhang, Y | 1 |
| Hume, JR; Ishikawa, T; Keef, KD | 1 |
| Bonev, AD; Mawe, GM; Nelson, MT; Zhang, L | 1 |
| Kanwal, S; Trachte, GJ | 1 |
| Boeckxstaens, GE; De Man, JG; Herman, AG; Pelckmans, PA | 1 |
| Gross, GW; Rhoades, BK | 1 |
| Husted, RF; Pruchno, CJ; Stokes, JB; Volk, KA | 1 |
| Barrett, JE; Hu, W; Sokol, PT; Toral, J; Yi, L; Ziai, MR | 1 |
| Andresen, MC; Reynolds, PJ; Yang, M | 1 |
| Boucher, A; Eng, JW; Hanrahan, JW; Harris, RA; Tabcharani, JA | 1 |
| Lou, YP; Lundberg, JM | 1 |
| Gelband, CH; Hume, JR; Ishikawa, T; Keef, KD; Post, JM | 1 |
| Cognard, C; Constantin, B; Raymond, G; Rivet-Bastide, M | 1 |
| Devor, DC; Frizzell, RA | 1 |
| Brayden, JE; McCarron, JG; Nelson, MT; Quayle, JM | 1 |
| Kunze, DL; Moak, JP | 1 |
| Eder, C; Fischer, HG; Hadding, U; Heinemann, U | 1 |
| Ficker, E; Heinemann, U; Klee, R | 1 |
| Dolly, JO; Nicholls, DG; Tibbs, GR | 1 |
| Foster, RW; Isaac, L; McArdle, S; Miller, NM; Small, RC | 1 |
| Carl, A; Koh, SD; Sanders, KM | 1 |
| Durell, SR; Guy, HR | 1 |
| Brady, G; Docherty, JR | 1 |
| Buckler, KJ | 1 |
| Katusic, ZS; Kinoshita, H | 1 |
| Horimoto, N; Nabekura, J; Ogawa, T | 1 |
| Bobbin, RP; Nenov, AP; Norris, C | 1 |
| Rubin, LJ; Wang, J; Yuan, XJ; Zhao, YJ | 1 |
| DeCoursey, TE; Kim, SY; Silver, MR | 1 |
| Edwards, G; Högestätt, ED; Larsson, B; Weston, AH; Zygmunt, PM | 1 |
| Romero, E; Sullivan, R | 1 |
| Katusic, ZS; Onoue, H | 3 |
| Maggi, CA; Santicioli, P | 1 |
| Alper, SL; Brugnara, C; Morgan, KG; Parker, C; Rittenhouse, AR | 1 |
| Hirono, M; Kawahara, K; Suzuki, N; Yoshioka, T | 1 |
| Buus, C; Mulvany, MJ; Nilsson, H; Prieto, D | 1 |
| Ito, T; Mokuno, S; Murase, K; Okumura, K; Shinoda, M; Toki, Y | 1 |
| Ashford, ML; Khan, RN; Morrison, JJ; Smith, SK | 1 |
| Akaike, N; Kakehata, S; Saito, H; Saito, T; Yamada, T; Yamamoto, T | 1 |
| Hiley, CR; White, R | 1 |
| Driesang, RB; Pape, HC | 1 |
| Hancox, JC; Levi, AJ; Skerry, TM; Yellowley, CE | 1 |
| Bojić, M; Djukanović, B; Gojkoviíc Bukarica, L; Kazić, T; Panić, G; Perić, M; Sajić, Z | 1 |
| Butcher, JW; Paton, JF | 1 |
| Paul, RJ; Shimizu, S | 1 |
| Sham, JS; Shimoda, LA; Sylvester, JT | 1 |
| Li, L; Paakkari, I; Vaali, K; Vapaatalo, H | 1 |
| Beech, DJ; Prior, HM; Yates, MS | 1 |
| Farrukh, IS; Hoidal, JR; Karwande, SV; Michael, JR; Peng, W | 1 |
| Sankaranarayanan, S; Simasko, SM | 1 |
| Kao, CY; Kao, PN; Sui, JL; Wakui, M; Wang, SY; Yoshino, M | 1 |
| Fukami, Y; Hibino, M; Ito, T; Nakashima, Y; Okumura, K; Toki, Y | 1 |
| Chen, CF; Chen, J; Chiou, WF | 1 |
| Abman, SH; Cornfield, DN; Kinsella, JP; Parker, TA; Rairigh, RL; Storme, L | 1 |
| Fukuta, H; Hashitani, H; Suzuki, H; Yamamoto, Y | 1 |
| Beirão, PS; Cordeiro, MN; Cruz, JS; Diniz, CR; Gomez, MV; Kalapothakis, E; Kushmerick, C; Penaforte, CL; Prado, MA; Prado, VF; Romano-Silva, MA | 1 |
| Farrukh, IS; Hoidal, JR; Peng, W | 1 |
| Ayala, GX; Bargas, J; Galarraga, E; Pineda, JC; Vilchis, C | 1 |
| Bryan, RM; Johnson, TD; Marrelli, SP; Mombouli, JV; You, J | 1 |
| Mills, JD; Pitman, RM | 1 |
| Adams, DJ; Catacuzzeno, L; Franciolini, F; Hogg, RC; Petris, A; Trequattrini, C | 1 |
| Narins, PM; Smotherman, MS | 1 |
| Lischka, FW; Restrepo, D; Teeter, JH | 1 |
| Kwan, HY; Yao, X | 1 |
| Laurier, LG; Preiksaitis, HG; Sims, SM; Wade, GR | 1 |
| Robertson, B; Southan, AP | 1 |
| Huguenard, JR; Kang, J; Prince, DA | 1 |
| Duarte, ID; Rodrigues, AR | 1 |
| Cox, G; Janssen, LJ; Keshavjee, S; Lu-Chao, H; Premji, M | 1 |
| Djamgoz, MB; Fraser, SP; Grimes, JA | 1 |
| Cole, WC; Dong, H; Jiang, Y; Triggle, CR | 1 |
| Archer, S; Bateson, J; Michelakis, E; Olley, P; Puttagunta, L; Rebeyka, I | 1 |
| Cobbett, P; Hlubek, MD | 1 |
| Bresson-Bepoldin, L; Czarnecki, A; Dufy, B; Dufy-Barbe, L; Vaur, S | 1 |
| Ghisdal, P; Gomez, JP; Morel, N | 1 |
| Bardou, M; Dumas, J; Dumas, M; Goirand, F; Rochette, L | 1 |
| Oliver, DL; Sivaramakrishnan, S | 1 |
| Lu, Y; Tang, G; Wang, R; Zhang, J | 1 |
| Gosche, JR | 1 |
| Garland, CJ; Plane, F; Sampson, LJ; Smith, JJ | 1 |
| Corriu, C; Côrtes, SF; Lemos, VS; Lopes, MJ; Medeiros, IA; Rezende, BA; Teixeira, MM | 1 |
| Duarte, ID; Soares, AC | 1 |
| Booth, GM; Meeker, S; Sham, JS; Shimoda, LA; Shimoda, TH; Sylvester, JT; Undem, BJ | 1 |
| Ghisdal, P; Morel, N | 1 |
| Chen, TT; Clément-Chomienne, O; Cole, WC; Ishii, K; Kerr, PM; Sontag, DP; Thorneloe, KS; Walsh, MP | 1 |
| Loutzenhiser, R; Wang, X | 1 |
| Li, L; Li, Y; Piao, L; Xu, WX | 1 |
| Chen, X; Namiki, A; Yamakage, M | 1 |
| Castañeda-Hernández, G; Granados-Soto, V; Ortiz, MI; Rosas, R; Torres-López, JE; Vidal-Cantú, GC | 1 |
| Breit, SN; Campbell, TJ; Qiu, MR | 1 |
| Abe, I; Fujii, K; Goto, K; Ohtsubo, T; Ohya, Y; Sadanaga, T | 1 |
| Argüelles, CF; Granados-Soto, V; Ortiz, MI | 1 |
| Castañeda-Hernández, G; Granados-Soto, V; Ortiz, MI | 2 |
| Gao, PJ; Jiao, S; Mei, YA; Wu, MM; Zang, ZH; Zhu, DL | 1 |
| El-Mahmoudy, A; Matsuyama, H; Shimizu, Y; Takewaki, T; Thapaliya, S | 1 |
| Hinton, JM; Langton, PD | 1 |
| Harhun, MI; Jurkiewicz, A; Jurkiewicz, NH; Kryshtal, DO; Shuba, MF; Vladimirova, IA | 1 |
| Burleigh, DE | 1 |
| Diss, JK; Djamgoz, MB; Dolly, JO; Fraser, SP; Grimes, JA; Stewart, D | 1 |
| Alves, DP; Amarante, LH; Duarte, ID | 1 |
| Anapolski, M; Barfield, JP; Cooper, TG; Yeung, CH | 1 |
| Dorange, G; Droguet, M; Gioux, M; Giroux-Metgès, MA; Pennec, JP; Talarmin, H | 1 |
| Bisseling, TM; Borggreven, JM; Copius Peereboom-Stegeman, JJ; Russel, FG; Smits, P; Steegers, EA; van der Laak, JA; van der Wal, S; Versteegen, MG | 1 |
| Annunziato, L; Calì, G; Pannaccione, A; Scorziello, A; Secondo, A; Taglialatela, M | 1 |
| Limón, A; Pérez, C; Soto, E; Vega, R | 1 |
| Fujimoto, S; Kunimatsu, M; Mori, M; Tsushima, H | 1 |
| Granados-Soto, V; Medina-Tato, DA; Ortiz, MI; Palma-Martínez, J; Sarmiento-Heredia, D | 1 |
| Djukanovic, B; Gojkovic-Bukarica, L; Heinle, H; Markovic-Lipkovski, J; Nezic, D; Novakovic, A; Peric, M | 1 |
| Bukarica, LG; Heinle, H; Kanjuh, V; Novakovic, A | 1 |
| Burg, ED; Firth, AL; Ko, EA; Msefya, J; Platoshyn, O; Yuan, JX | 1 |
| Kito, Y; Suzuki, H | 1 |
| Akar, F; Katircioglu, SF; Manavbasi, Y; Parlar, AI; Ulus, AT | 1 |
| Buxton, BF; Hare, DL; Wookey, PJ; Ye, B; Zulli, A | 1 |
| Adaramoye, OA; Medeiros, IA | 1 |
| Draheim, HJ; Lamodière, E; Moussaud, S; Savage, C | 1 |
| CHEN, YH; HSIEH, CL; HSU, HY; HUANG, SS; LIN, JG; LIN, PL; LU, DY; WU, YT; YANG, HY | 1 |
| Aiba, A; Inokuchi, K; Inoue, N; Kato, N; Ueta, Y; Wang, L; Yamamoto, K; Yamamoto, R; Yonekura, H | 1 |
| Nakamura, K; Shimizu, T; Tanaka, K; Taniuchi, K; Yokotani, K | 1 |
| Bayram, Z; Nacitarhan, C; Ozdem, SS | 1 |
| Dias, FM; Fernandes, AA; Fiorim, J; Ribeiro, RF; Stefanon, I; Travaglia, TC; Vassallo, DV | 1 |
1 review(s) available for 4-aminopyridine and charybdotoxin
| Article | Year |
|---|---|
Action potential repolarization and a fast after-hyperpolarization in rat hippocampal pyramidal cells.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Charybdotoxin; Hippocampus; In Vitro Techniques; Ion Channels; Neurons; Norepinephrine; Potassium; Rats; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1987 |
138 other study(ies) available for 4-aminopyridine and charybdotoxin
| Article | Year |
|---|---|
Block of potassium outward currents in the crayfish stretch receptor neurons by 4-aminopyridine, tetraethylammonium chloride and some other chemical substances.
Topics: 4-Aminopyridine; Animals; Apamin; Astacoidea; Carbachol; Charybdotoxin; In Vitro Techniques; Kinetics; Mechanoreceptors; Muscles; Neurons; Potassium Channels; Reflex; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1992 |
Noxiustoxin and leiurutoxin III, two homologous peptide toxins with binding properties to synaptosomal membrane K+ channels.
Topics: 4-Aminopyridine; Amino Acid Sequence; Animals; Binding Sites; Charybdotoxin; Intercellular Signaling Peptides and Proteins; Kinetics; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neurotoxins; Peptides; Potassium Channels; Scorpion Venoms; Sequence Homology, Amino Acid; Synaptic Membranes; Synaptosomes; Tetraethylammonium; Tetraethylammonium Compounds | 1992 |
Ca(2+)-activated K+ channels in human leukemic T cells.
Topics: 4-Aminopyridine; Apamin; Calcium; Charybdotoxin; Humans; Ionomycin; Leukemia, T-Cell; Phytohemagglutinins; Potassium; Potassium Channels; Scorpion Venoms; Tumor Cells, Cultured | 1992 |
Characterization of a delayed rectifier potassium current in chicken growth plate chondrocytes.
Topics: 4-Aminopyridine; Animals; Cartilage; Cells, Cultured; Charybdotoxin; Chickens; Chlorides; Electric Conductivity; Growth Plate; Potassium; Scorpion Venoms; Zinc; Zinc Compounds | 1992 |
Ionic currents in single smooth muscle cells of the canine renal artery.
Topics: 4-Aminopyridine; Angiotensin II; Animals; Calcium Channels; Charybdotoxin; Dogs; Electrophysiology; Female; In Vitro Techniques; Male; Membrane Potentials; Models, Biological; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Channels; Renal Artery; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1992 |
Ca2+ release from isolated sarcoplasmic reticulum of guinea-pig psoas muscle induced by K(+)-channel blockers.
Topics: 4-Aminopyridine; Animals; Apamin; Calcium; Charybdotoxin; Glyburide; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Potassium Channels; Psoas Muscles; Sarcoplasmic Reticulum; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1992 |
Evidence for two calcium-dependent potassium conductances in lizard motor nerve terminals.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Action Potentials; Animals; Apamin; Caffeine; Calcium; Charybdotoxin; Egtazic Acid; Electric Conductivity; Lizards; Motor Neurons; Muscle Contraction; Nerve Endings; Potassium; Procaine; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1990 |
Alternative Shaker transcripts express either rapidly inactivating or noninactivating K+ channels.
Topics: 4-Aminopyridine; Animals; Charybdotoxin; Drosophila melanogaster; Elapid Venoms; Electric Conductivity; In Vitro Techniques; Membrane Potentials; Oocytes; Peptides; Potassium Channels; RNA Splicing; RNA, Messenger; Scorpion Venoms; Structure-Activity Relationship; Tetraethylammonium; Tetraethylammonium Compounds; Xenopus laevis | 1990 |
K+ efflux pathways and neurotransmitter release associated to hippocampal ischemia: effects of glucose and of K+ channel blockers.
Topics: 4-Aminopyridine; Animals; Apamin; Aspartic Acid; Barium; Barium Compounds; Brain Ischemia; Calcium Chloride; Charybdotoxin; Chlorides; Elapid Venoms; gamma-Aminobutyric Acid; Glipizide; Glucose; Glyburide; Hippocampus; In Vitro Techniques; Kinetics; Potassium; Potassium Channels; Rats; Rats, Inbred Strains; Rubidium; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
K+ channel and 5-hydroxytryptamine1A autoreceptor interactions in the rat dorsal raphe nucleus: an in vitro electrophysiological study.
Topics: 4-Aminopyridine; Animals; Anti-Anxiety Agents; Apamin; Barium; Charybdotoxin; Electrophysiology; Evoked Potentials; Male; Neurons; Phenylephrine; Potassium Channels; Propranolol; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Scorpion Venoms; Spiperone | 1991 |
Voltage-dependent K+ currents and underlying single K+ channels in pheochromocytoma cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Charybdotoxin; Ion Channels; Membrane Potentials; Pheochromocytoma; Potassium; Quinidine; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1988 |
Glyburide blocks the relaxation response to BRL 34915 (cromakalim), minoxidil sulfate and diazoxide in vascular smooth muscle.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Antihypertensive Agents; Benzopyrans; Charybdotoxin; Cromakalim; Diazoxide; Glyburide; Male; Minoxidil; Muscle, Smooth, Vascular; Potassium Channels; Pyrroles; Rats; Rats, Inbred Strains; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Vasodilation | 1989 |
Effects of charybdotoxin, a blocker of Ca2+-activated K+ channels, on motor nerve terminals.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Animals; Apamin; Calcium; Charybdotoxin; In Vitro Techniques; Membrane Potentials; Mice; Motor Endplate; Neuromuscular Junction; Potassium Channels; Scorpion Venoms | 1988 |
Expression of Drosophila Shaker potassium channels in mammalian cells infected with recombinant vaccinia virus.
Topics: 4-Aminopyridine; Animals; Cell Line; Cell Transformation, Viral; Cells, Cultured; Charybdotoxin; Cloning, Molecular; DNA, Recombinant; Drosophila; Gene Expression; Membrane Potentials; Membrane Proteins; Plasmids; Potassium Channels; Scorpion Venoms; Vaccinia virus | 1989 |
Charybdotoxin inhibits proliferation and interleukin 2 production in human peripheral blood lymphocytes.
Topics: 4-Aminopyridine; Cells, Cultured; Charybdotoxin; Humans; Interleukin-2; Kinetics; Lymphocyte Activation; Lymphocytes; Quinine; Scorpion Venoms; T-Lymphocytes; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
The effects of K+ channel blockers on the spontaneous electrical and contractile activity in the proximal renal pelvis of the guinea pig.
Topics: 4-Aminopyridine; Action Potentials; Animals; Apamin; Charybdotoxin; Female; Glyburide; Guinea Pigs; Kidney Pelvis; Male; Muscle Contraction; Muscle, Smooth; Potassium Channel Blockers; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds | 1996 |
Modulation of K+ and Ca2+ channels by histamine H1-receptor stimulation in rabbit coronary artery cells.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channels; Charybdotoxin; Coronary Vessels; Histamine Agonists; In Vitro Techniques; Male; Potassium Channels; Pyridines; Rabbits; Receptors, Histamine H1; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Vasoconstriction | 1993 |
Ionic basis of the action potential of guinea pig gallbladder smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Action Potentials; Animals; Calcium Channels; Cell Membrane; Charybdotoxin; Electrophysiology; Female; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth; Nifedipine; Potassium Channel Blockers; Potassium Channels; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1993 |
Potassium channel inhibitors attenuate neuromodulatory effects of atrial natriuretic factor in the rabbit isolated vas deferens.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Benzopyrans; Charybdotoxin; Cromakalim; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Potassium Channel Blockers; Potassium Channels; Prazosin; Pyrroles; Rabbits; Receptors, Adrenergic; Scorpion Venoms; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds; Vas Deferens | 1994 |
Effect of potassium channel blockade and alpha 2-adrenoceptor activation on the release of nitric oxide from non-adrenergic non-cholinergic nerves.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Animals; Arginine; Autonomic Nervous System; Brimonidine Tartrate; Charybdotoxin; Dogs; Electric Stimulation; Female; Male; Nitric Oxide; Nitroarginine; Potassium Channels; Quinoxalines; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Tetraethylammonium Compounds; Tetrodotoxin; Yohimbine | 1994 |
Potassium and calcium channel dependence of bursting in cultured neuronal networks.
Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Apamin; Barium Compounds; Bicuculline; Calcium Channels; Cesium; Charybdotoxin; Chlorides; Choline; Diltiazem; Electrophysiology; Fetus; Magnesium Chloride; Mice; Muscarine; N-Methylaspartate; Nerve Net; Neurons; Organ Culture Techniques; Ouabain; Potassium Channels; Potassium Chloride; Scorpion Venoms; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Veratridine | 1994 |
Functional and molecular evidence for Shaker-like K+ channels in rabbit renal papillary epithelial cell line.
Topics: 4-Aminopyridine; Amiloride; Animals; Base Sequence; Calcium; Cell Line; Charybdotoxin; DNA Primers; Drosophila; Egtazic Acid; Elapid Venoms; Epithelium; Kidney Medulla; Kidney Tubules, Collecting; Membrane Potentials; Models, Biological; Molecular Sequence Data; Nephrons; Pancreatitis-Associated Proteins; Polymerase Chain Reaction; Potassium; Potassium Channel Blockers; Potassium Channels; Rabbits; RNA, Messenger; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1994 |
Use of cultured human neuroblastoma cells in rapid discovery of the voltage-gated potassium-channel blockers.
Topics: 4-Aminopyridine; Barium; Charybdotoxin; Humans; Membrane Potentials; Neuroblastoma; Neurons; Potassium; Potassium Channel Blockers; Rubidium Radioisotopes; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1994 |
Contribution of potassium channels to the discharge properties of rat aortic baroreceptor sensory endings.
Topics: 4-Aminopyridine; Animals; Aorta; Charybdotoxin; Male; Nerve Endings; Potassium Channel Blockers; Potassium Channels; Prazosin; Pressoreceptors; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1994 |
Basolateral K channel activated by carbachol in the epithelial cell line T84.
Topics: 4-Aminopyridine; Calcimycin; Carbachol; Cell Membrane; Charybdotoxin; Colonic Neoplasms; Cyclic AMP; Epithelium; Fluorescence; Humans; Ionomycin; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Quinidine; Scorpion Venoms; Temperature; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Tumor Cells, Cultured | 1994 |
Different effects of the K+ channel blockers 4-aminopyridine and charybdotoxin on sensory nerves in guinea-pig lung.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Animals; Atropine; Bronchi; Calcitonin Gene-Related Peptide; Charybdotoxin; Electric Stimulation; Female; Guanethidine; Guinea Pigs; Imidazoles; In Vitro Techniques; Lung; Male; Neurons, Afferent; Potassium Channels; Scorpion Venoms | 1993 |
Intracellular divalent cations block smooth muscle K+ channels.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channels; Charybdotoxin; Dogs; Egtazic Acid; Electrophysiology; Magnesium; Membrane Potentials; Muscle, Smooth, Vascular; Potassium Channels; Pyridines; Rabbits; Ryanodine; Scorpion Venoms | 1993 |
Activation of a slow outward current by the calcium released during contraction of cultured rat skeletal muscle cells.
Topics: 4-Aminopyridine; Animals; Apamin; Caffeine; Calcium; Cells, Cultured; Cesium; Charybdotoxin; Egtazic Acid; Electric Conductivity; Electric Stimulation; Membrane Potentials; Muscle Contraction; Muscles; Nifedipine; Potassium; Rats; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1993 |
Calcium-mediated agonists activate an inwardly rectified K+ channel in colonic secretory cells.
Topics: 4-Aminopyridine; Animals; Apamin; Barium; Calcium; Cell Line; Charybdotoxin; Colon; Cytosol; Glyburide; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Potassium Channels; Quinine; Scorpion Venoms; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1993 |
Inward rectifier K+ currents in smooth muscle cells from rat resistance-sized cerebral arteries.
Topics: 4-Aminopyridine; Animals; Barium; Cerebral Arteries; Charybdotoxin; Female; Glyburide; Kinetics; Membrane Potentials; Muscle, Smooth, Vascular; Potassium; Potassium Channels; Rats; Rats, Inbred WKY; Scorpion Venoms | 1993 |
Potassium currents of neurons isolated from medical nucleus tractus solitarius.
Topics: 4-Aminopyridine; Animals; Apamin; Calcium; Charybdotoxin; Egtazic Acid; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Neurons; Potassium Channels; Scorpion Venoms; Solitary Nucleus; Tetraethylammonium; Tetraethylammonium Compounds; Tubocurarine | 1993 |
Properties of voltage-gated potassium currents of microglia differentiated with granulocyte/macrophage colony-stimulating factor.
Topics: 4-Aminopyridine; Animals; Cations, Divalent; Cell Differentiation; Cells, Cultured; Charybdotoxin; Granulocyte-Macrophage Colony-Stimulating Factor; Ion Channel Gating; Ion Transport; Kinetics; Membrane Potentials; Mice; Microglia; Potassium; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Comparison of voltage-dependent potassium currents in rat pyramidal neurons acutely isolated from hippocampal regions CA1 and CA3.
Topics: 4-Aminopyridine; Animals; Calcium; Charybdotoxin; Elapid Venoms; Embryonic and Fetal Development; In Vitro Techniques; Kinetics; Membrane Potentials; Neurotoxins; Patch-Clamp Techniques; Peptides; Potassium Channels; Pyramidal Cells; Rats; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Evidence for the induction of repetitive action potentials in synaptosomes by K+-channel inhibitors: an analysis of plasma membrane ion fluxes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cell Membrane; Charybdotoxin; Elapid Venoms; Fura-2; Guinea Pigs; Ion Channels; Peptides; Potassium Channel Blockers; Rubidium Radioisotopes; Synaptosomes; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Veratridine | 1996 |
Effects of some K(+)-channel inhibitors on the electrical behaviour of guinea-pig isolated trachealis and on its responses to spasmogenic drugs.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Charybdotoxin; Electrophysiology; Female; Glyburide; Guinea Pigs; Histamine; Hypoglycemic Agents; Male; Muscle, Smooth; Parasympatholytics; Peptides; Phenethylamines; Potassium Channel Blockers; Scorpion Venoms; Sulfonamides; Trachea | 1996 |
Regulation of smooth muscle delayed rectifier K+ channels by protein kinase A.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Calcium; Charybdotoxin; Colon; Cyclic AMP-Dependent Protein Kinases; Dogs; Female; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth; Patch-Clamp Techniques; Potassium Channels; Tetraethylammonium Compounds | 1996 |
Structural model of the outer vestibule and selectivity filter of the Shaker voltage-gated K+ channel.
Topics: 4-Aminopyridine; Charybdotoxin; Ion Channel Gating; Models, Molecular; Mutation; Potassium Channels; Protein Structure, Secondary; Scorpion Venoms; Shaker Superfamily of Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Toxins, Biological | 1996 |
Prejunctional actions of K+ channel blockers in rat vas deferens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Adenosine Triphosphate; Anesthetics; Animals; Apamin; Calcium; Charybdotoxin; Electric Stimulation; Enzyme Activation; Isometric Contraction; Male; Neuromuscular Junction; Norepinephrine; Phorbol 12,13-Dibutyrate; Potassium Channel Blockers; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Tetraethylammonium; Tetraethylammonium Compounds; Vas Deferens; Xylazine | 1995 |
Role of potassium channels in hypoxic chemoreception in rat carotid body type-I cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Carotid Body; Charybdotoxin; Hypoxia; Ion Channel Gating; Ion Transport; Membrane Potentials; Nerve Tissue Proteins; Oxygen; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetraethylammonium Compounds | 1996 |
Role of potassium channels in relaxations of isolated canine basilar arteries to acidosis.
Topics: 4-Aminopyridine; Acidosis; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Barium Compounds; Basilar Artery; Calcium Channel Blockers; Charybdotoxin; Chlorides; Dogs; Endothelium, Vascular; Female; Glyburide; Hydrogen-Ion Concentration; Ion Channel Gating; KATP Channels; Male; Molsidomine; Muscle, Smooth, Vascular; Potassium Channels; Potassium Channels, Inwardly Rectifying; Uridine Triphosphate; Vasodilation | 1997 |
Arachidonic acid activation of potassium channels in rat visual cortex neurons.
Topics: 4-Aminopyridine; Animals; Apamin; Arachidonic Acid; Barium; Charybdotoxin; Docosahexaenoic Acids; Egtazic Acid; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Glyburide; In Vitro Techniques; Indomethacin; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Quinidine; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetraethylammonium Compounds; Visual Cortex | 1997 |
Outwardly rectifying currents in guinea pig outer hair cells.
Topics: 4-Aminopyridine; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Separation; Charybdotoxin; Guinea Pigs; Hair Cells, Auditory, Outer; Ion Transport; Patch-Clamp Techniques; Potassium; Potassium Channels | 1997 |
Inhibition of K(V) and K(Ca) channels antagonizes NO-induced relaxation in pulmonary artery.
Topics: 4-Aminopyridine; Aminoquinolines; Animals; Calcium; Charybdotoxin; Electrophysiology; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Nitric Oxide; Nitroprusside; Potassium; Potassium Channel Blockers; Potassium Channels; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 1997 |
Ion channels in human THP-1 monocytes.
Topics: 4-Aminopyridine; Apamin; Calcium; Cations, Divalent; Charybdotoxin; Chloride Channels; Humans; Ion Channel Gating; Ion Channels; Leukemia, Monocytic, Acute; Monocytes; Neoplasm Proteins; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Tetraethylammonium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1996 |
Involvement of voltage-dependent potassium channels in the EDHF-mediated relaxation of rat hepatic artery.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Anti-Arrhythmia Agents; Apamin; Binding, Competitive; Biological Factors; Cerebral Cortex; Charybdotoxin; Chromans; Cyclooxygenase Inhibitors; Drug Interactions; Female; Hepatic Artery; Indoles; Indomethacin; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Patch-Clamp Techniques; Phenethylamines; Piperidines; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sulfonamides | 1997 |
Complexity of the outward K+ current of the rat megakaryocyte.
Topics: 4-Aminopyridine; Animals; Charybdotoxin; Electric Conductivity; Electrophysiology; Kinetics; Megakaryocytes; Potassium Channels; Quaternary Ammonium Compounds; Rats; Rats, Wistar | 1997 |
Role of potassium channels in relaxations of canine middle cerebral arteries induced by nitric oxide donors.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; 4-Aminopyridine; Animals; Barium Compounds; Cerebral Arteries; Charybdotoxin; Chlorides; Cyclic GMP; Diltiazem; Dogs; Glyburide; In Vitro Techniques; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Potassium Channels; Purinones; Vasodilation; Vasodilator Agents | 1997 |
Pharmacological modulation of electromechanical coupling in the proximal and distal regions of the guinea-pig renal pelvis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Action Potentials; Animals; Calcium Channel Blockers; Calcium-Transporting ATPases; Charybdotoxin; Electrophysiology; Enzyme Inhibitors; Guinea Pigs; Indoles; Kidney Pelvis; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Channels; Sarcoplasmic Reticulum; Tetraethylammonium; Tetraethylammonium Compounds | 1997 |
Inhibition of maxi-K currents in ferret portal vein smooth muscle cells by the antifungal clotrimazole.
Topics: 4-Aminopyridine; Animals; Antifungal Agents; Cells, Cultured; Charybdotoxin; Clotrimazole; Cytochrome P-450 Enzyme System; Electric Conductivity; Ferrets; Glyburide; Ion Channel Gating; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Peptides; Portal Vein; Potassium Channel Blockers; Tetraethylammonium; Tetraethylammonium Compounds; Toxins, Biological | 1997 |
Sapecin B, a novel fly toxin, blocks macroscopic K+ currents in the GH3 rat pituitary cell line.
Topics: 4-Aminopyridine; Animals; Charybdotoxin; Diptera; Insect Proteins; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; Patch-Clamp Techniques; Pituitary Gland, Anterior; Pituitary Neoplasms; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Scorpion Venoms; Tetrodotoxin; Time Factors; Tumor Cells, Cultured | 1997 |
Interactions between neuropeptide Y and the adenylate cyclase pathway in rat mesenteric small arteries: role of membrane potential.
Topics: 4-Aminopyridine; Acetylcholine; Adenylyl Cyclases; Animals; Charybdotoxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dichlororibofuranosylbenzimidazole; Gadolinium; Glyburide; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Neuropeptide Y; Nifedipine; Potassium Channels; Rats; Rats, Wistar; Thionucleotides | 1997 |
Types of potassium channels involved in coronary reactive hyperemia depend on duration of preceding ischemia in rat hearts.
Topics: 4-Aminopyridine; Adenosine Diphosphate; Animals; Apamin; Charybdotoxin; Glyburide; Hyperemia; In Vitro Techniques; Indomethacin; Male; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels; Rats; Rats, Wistar; Regional Blood Flow; Tetraethylammonium; Tetraethylammonium Compounds | 1997 |
Ca2+ dependence and pharmacology of large-conductance K+ channels in nonlabor and labor human uterine myocytes.
Topics: 4-Aminopyridine; Barium; Calcium; Cells, Cultured; Charybdotoxin; Female; Humans; Ion Channel Gating; Labor, Obstetric; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Muscle, Smooth; Myometrium; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Calcium-Activated; Pregnancy; Reference Values; Tetraethylammonium | 1997 |
Effects of potassium channel blockers on the acetylcholine-induced currents in dissociated outer hair cells of guinea pig cochlea.
Topics: 4-Aminopyridine; Acetylcholine; Analgesics, Non-Narcotic; Animals; Apamin; Charybdotoxin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hair Cells, Auditory, Outer; Male; Nicotinic Antagonists; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Potassium Channels; Quinidine; Quinine; Scorpion Venoms; Tetraethylammonium; Tubocurarine | 1997 |
A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery.
Topics: 4-Aminopyridine; Animals; Apamin; Arachidonic Acids; Barium; Biological Factors; Calcium Channel Blockers; Charybdotoxin; Endocannabinoids; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Indoles; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Peptides; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Potassium; Potassium Channel Blockers; Protease Inhibitors; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tosyl Compounds; Vasodilation; Virulence Factors, Bordetella | 1997 |
Ionic mechanisms of intrinsic oscillations in neurons of the basolateral amygdaloid complex.
Topics: 4-Aminopyridine; Amygdala; Animals; Apamin; Barium; Calcium; Cations, Divalent; Cesium; Charybdotoxin; Egtazic Acid; Evoked Potentials; Fourier Analysis; Guinea Pigs; In Vitro Techniques; Magnesium; Membrane Potentials; Neurons; Oscillometry; Peptides; Sodium; Tetraethylammonium; Tetrodotoxin | 1998 |
Whole-cell membrane currents from human osteoblast-like cells.
Topics: 4-Aminopyridine; Barium; Cell Membrane; Charybdotoxin; Ethylamines; Humans; Ion Channels; Membrane Potentials; Models, Biological; Osteoblasts; Osteosarcoma; Patch-Clamp Techniques; Potassium; Tumor Cells, Cultured | 1998 |
The effects of levcromakalim and pinacidil on the human internal mammary artery.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Apamin; Charybdotoxin; Coronary Artery Bypass; Coronary Disease; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Guanidines; Humans; In Vitro Techniques; Male; Mammary Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Pinacidil; Potassium Channels; Tetraethylammonium; Vasodilation; Vasodilator Agents | 1997 |
Subarachnoid hemorrhage and the role of potassium channels in relaxations of canine basilar artery to nitrovasodilators.
Topics: 4-Aminopyridine; Animals; Basilar Artery; Charybdotoxin; Cyclic GMP; Dogs; Female; Humans; Male; Molsidomine; Nitroprusside; Potassium Channels; Subarachnoid Hemorrhage; Uridine Triphosphate; Vasodilation; Vasodilator Agents | 1998 |
K+ channel blockade in the NTS alters efficacy of two cardiorespiratory reflexes in vivo.
Topics: 4-Aminopyridine; Animals; Baroreflex; Biguanides; Blood Pressure; Calcium; Charybdotoxin; Elapid Venoms; Heart Rate; Male; Microinjections; Phenylephrine; Potassium; Potassium Channel Blockers; Pressoreceptors; Rats; Rats, Sprague-Dawley; Reflex; Respiration; Solitary Nucleus | 1998 |
The endothelium-dependent, substance P relaxation of porcine coronary arteries resistant to nitric oxide synthesis inhibition is partially mediated by 4-aminopyridine-sensitive voltage-dependent K+ channels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Animals; Apamin; Calcium; Charybdotoxin; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Ion Transport; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Potassium Channels; Quaternary Ammonium Compounds; Substance P; Swine | 1997 |
Inhibition of voltage-gated K+ current in rat intrapulmonary arterial myocytes by endothelin-1.
Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Charybdotoxin; Electrophysiology; Endothelin-1; Enzyme Inhibitors; Ion Channel Gating; Male; Membrane Potentials; Muscle, Smooth, Vascular; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Pulmonary Artery; Rats; Rats, Wistar; Type C Phospholipases; Vasoconstriction | 1998 |
The effect of subarachnoid hemorrhage on mechanisms of vasodilation mediated by cyclic adenosine monophosphate.
Topics: 4-Aminopyridine; Adenylyl Cyclases; Animals; Basilar Artery; Charybdotoxin; Colforsin; Cyclic AMP; Disease Models, Animal; Dogs; Endothelium, Vascular; Enzyme Activation; Female; Glyburide; Ischemic Attack, Transient; Male; Potassium Channel Blockers; Potassium Channels; Subarachnoid Hemorrhage; Vasodilation; Vasodilator Agents | 1998 |
Relaxing effects of NO donors on guinea pig trachea in vitro are mediated by calcium-sensitive potassium channels.
Topics: 4-Aminopyridine; Animals; Calcium; Charybdotoxin; Female; Glyburide; Guinea Pigs; Male; Molsidomine; Nitric Oxide; Peptides; Potassium Channels; Trachea; Triazoles | 1998 |
Functions of large conductance Ca2+-activated (BKCa), delayed rectifier (KV) and background K+ channels in the control of membrane potential in rabbit renal arcuate artery.
Topics: 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amifampridine; Animals; Apamin; Arteries; Barium; Charybdotoxin; Glyburide; In Vitro Techniques; Kidney; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Muscle, Smooth, Vascular; Ouabain; Peptides; Potassium Channels; Potassium Channels, Calcium-Activated; Rabbits; Scorpion Venoms; Vasoconstriction | 1998 |
ET-1 modulates KCa-channel activity and arterial tension in normoxic and hypoxic human pulmonary vasculature.
Topics: 4-Aminopyridine; Analysis of Variance; Cell Hypoxia; Cells, Cultured; Charybdotoxin; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Humans; In Vitro Techniques; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; Lung Diseases, Obstructive; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Peptides, Cyclic; Potassium Channels; Potassium Channels, Calcium-Activated; Pulmonary Artery; Receptor, Endothelin A; Thapsigargin | 1998 |
Potassium channel blockers have minimal effect on repolarization of spontaneous action potentials in rat pituitary lactotropes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Apamin; Calcium; Charybdotoxin; Chelating Agents; Clone Cells; Female; Patch-Clamp Techniques; Pituitary Gland, Anterior; Potassium Channel Blockers; Rats; Tetraethylammonium | 1998 |
Potassium currents in freshly dissociated uterine myocytes from nonpregnant and late-pregnant rats.
Topics: 4-Aminopyridine; Animals; Apamin; Calcium; Charybdotoxin; Elapid Venoms; Female; In Vitro Techniques; Kinetics; Membrane Potentials; Myometrium; Peptides; Photolysis; Potassium Channels; Pregnancy; Pregnancy, Animal; Rats; Tetraethylammonium | 1998 |
Role of K+ channels in EDHF-dependent relaxation induced by acetylcholine in canine coronary artery.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Apamin; Biological Factors; Charybdotoxin; Coronary Vessels; Dogs; Enzyme Inhibitors; Female; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Quaternary Ammonium Compounds; Toxins, Biological; Vasodilation; Vasodilator Agents | 1997 |
Relaxation of corpus cavernosum and raised intracavernous pressure by berberine in rabbit.
Topics: 4-Aminopyridine; Animals; Apamin; Berberine; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Male; Muscle Relaxation; Penis; Potassium; Potassium Channel Blockers; Pressure; Rabbits | 1998 |
K+-channel blockade inhibits shear stress-induced pulmonary vasodilation in the ovine fetus.
Topics: 4-Aminopyridine; Animals; Charybdotoxin; Fetus; Hemodynamics; Potassium Channel Blockers; Pulmonary Circulation; Sheep; Stress, Mechanical; Tetraethylammonium; Vascular Resistance; Vasodilation | 1999 |
Calcium responses induced by acetylcholine in submucosal arterioles of the guinea-pig small intestine.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Arachidonic Acid; Arterioles; Calcium; Charybdotoxin; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Guinea Pigs; Intestinal Mucosa; Intestine, Small; Male; Muscarinic Antagonists; Nitric Oxide; Potassium Channel Blockers | 1999 |
Phoneutria nigriventer toxin Tx3-1 blocks A-type K+ currents controlling Ca2+ oscillation frequency in GH3 cells.
Topics: 4-Aminopyridine; Amino Acid Sequence; Base Sequence; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Charybdotoxin; Chelating Agents; DNA, Complementary; Egtazic Acid; Ion Channel Gating; Membrane Potentials; Molecular Sequence Data; Neuropeptides; Nifedipine; Patch-Clamp Techniques; Periodicity; Pituitary Gland; Potassium Channel Blockers; Potassium Channels; Spider Venoms | 1999 |
Role of a novel KCa opener in regulating K+ channels of hypoxic human pulmonary vascular cells.
Topics: 4-Aminopyridine; Cell Hypoxia; Cells, Cultured; Charybdotoxin; Cyclic AMP; Cyclic GMP; Dehydroepiandrosterone; Egtazic Acid; Enzyme Inhibitors; Humans; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Potassium Channels, Voltage-Gated; Protein Kinase Inhibitors; Pulmonary Circulation; Thionucleotides | 1999 |
Ca2+-activated outward currents in neostriatal neurons.
Topics: 4-Aminopyridine; Animals; Apamin; Barium; Cadmium; Calcium; Charybdotoxin; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Neostriatum; Neurons; Patch-Clamp Techniques; Peptides; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Tetraethylammonium; Tetrodotoxin | 1999 |
P2u receptor-mediated release of endothelium-derived relaxing factor/nitric oxide and endothelium-derived hyperpolarizing factor from cerebrovascular endothelium in rats.
Topics: 4-Aminopyridine; Animals; Apamin; Barium Compounds; Cerebral Arteries; Cerebrovascular Circulation; Charybdotoxin; Chlorides; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Peptides; Potassium Channels; Potassium Chloride; Quinoxalines; Rats; Rats, Long-Evans; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Tetraethylammonium; Uridine Triphosphate; Vasodilation | 1999 |
Contribution of potassium conductances to a time-dependent transition in electrical properties of a cockroach motoneuron soma.
Topics: 4-Aminopyridine; Action Potentials; Animals; Apamin; Charybdotoxin; Cockroaches; Electric Conductivity; Electrophysiology; Homeostasis; Male; Motor Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Time Factors | 1999 |
Mechanisms of verapamil inhibition of action potential firing in rat intracardiac ganglion neurons.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Animals; Animals, Newborn; Apamin; Cells, Cultured; Charybdotoxin; Electric Stimulation; Ganglia, Parasympathetic; Heart; Membrane Potentials; Muscarine; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Tetraethylammonium; Verapamil | 1999 |
The electrical properties of auditory hair cells in the frog amphibian papilla.
Topics: 4-Aminopyridine; Animals; Barium Compounds; Cadmium Chloride; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Size; Charybdotoxin; Chlorides; Electric Conductivity; Hair Cells, Auditory; Hearing; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Patch-Clamp Techniques; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Rana pipiens; Tetraethylammonium | 1999 |
Odorants suppress a voltage-activated K+ conductance in rat olfactory neurons.
Topics: 4-Aminopyridine; Animals; Apamin; Charybdotoxin; Cobalt; Cyclic AMP; Electric Stimulation; In Vitro Techniques; Ion Channel Gating; Male; Membrane Potentials; Nitriles; Odorants; Olfactory Receptor Neurons; Potassium Channels; Rats; Rats, Sprague-Dawley; Reaction Time; Signal Transduction; Tetraethylammonium | 1999 |
Activity of voltage-gated K+ channels is associated with cell proliferation and Ca2+ influx in carcinoma cells of colon cancer.
Topics: 4-Aminopyridine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carbamates; Cell Division; Charybdotoxin; Colonic Neoplasms; Glyburide; Humans; Ion Channel Gating; Nickel; Peptides; Phenylcarbamates; Potassium; Potassium Channel Blockers; Potassium Channels; Quaternary Ammonium Compounds; RNA, Messenger; Tetraethylammonium; Tumor Cells, Cultured | 1999 |
Delayed rectifier and Ca(2+)-dependent K(+) currents in human esophagus: roles in regulating muscle contraction.
Topics: 4-Aminopyridine; Calcium; Charybdotoxin; Delayed Rectifier Potassium Channels; Electric Conductivity; Esophagus; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Peptides; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Reverse Transcriptase Polymerase Chain Reaction; Tetraethylammonium; Tetrodotoxin | 1999 |
Electrophysiological characterization of voltage-gated K(+) currents in cerebellar basket and purkinje cells: Kv1 and Kv3 channel subfamilies are present in basket cell nerve terminals.
Topics: 4-Aminopyridine; Animals; Apamin; Brain Chemistry; Charybdotoxin; Dose-Response Relationship, Drug; Elapid Venoms; Ion Channel Gating; Kv1.1 Potassium Channel; Kv1.2 Potassium Channel; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Neurotoxins; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Presynaptic Terminals; Purkinje Cells; Scorpion Venoms; Shaw Potassium Channels; Tetraethylammonium | 2000 |
Voltage-gated potassium channels activated during action potentials in layer V neocortical pyramidal neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Charybdotoxin; Electric Stimulation; Female; In Vitro Techniques; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Male; Neocortex; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Calcium-Activated; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Tetraethylammonium | 2000 |
The peripheral antinociceptive effect induced by morphine is associated with ATP-sensitive K(+) channels.
Topics: 4-Aminopyridine; Analgesics, Opioid; Animals; Apamin; ATP-Binding Cassette Transporters; Cesium; Charybdotoxin; Drug Interactions; Hyperalgesia; Hypoglycemic Agents; KATP Channels; Large-Conductance Calcium-Activated Potassium Channels; Male; Morphine; Pain Measurement; Peripheral Nerves; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Tetraethylammonium | 2000 |
NO(+) but not NO radical relaxes airway smooth muscle via cGMP-independent release of internal Ca(2+).
Topics: 4-Aminopyridine; Animals; Bronchi; Calcium; Calcium-Transporting ATPases; Charybdotoxin; Cyclic GMP; Dithiothreitol; Dogs; Enzyme Activation; Free Radicals; Guanylate Cyclase; Humans; In Vitro Techniques; Molsidomine; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Oxidation-Reduction; Penicillamine; Potassium Channels; Potassium Chloride; Tetraethylammonium; Trachea | 2000 |
Effects of voltage-gated ion channel modulators on rat prostatic cancer cell proliferation: comparison of strongly and weakly metastatic cell lines.
Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Cell Division; Charybdotoxin; Dose-Response Relationship, Drug; Formazans; Ion Channel Gating; Male; Neurotoxins; Patch-Clamp Techniques; Potassium Channels; Prostatic Neoplasms; Rats; Scorpion Venoms; Sodium Channels; Tetrazolium Salts; Tetrodotoxin; Tumor Cells, Cultured; Verapamil; Veratridine | 2000 |
Comparison of the pharmacological properties of EDHF-mediated vasorelaxation in guinea-pig cerebral and mesenteric resistance vessels.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Arachidonic Acids; Biological Factors; Cerebral Arteries; Charybdotoxin; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Ouabain; Oxadiazoles; Potassium Channel Blockers; Potassium Channels; Quinoxalines; Vasodilation; Vasodilator Agents | 2000 |
Voltage-gated potassium channels in human ductus arteriosus.
Topics: 4-Aminopyridine; Charybdotoxin; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, Patent; Endothelin-1; Glyburide; Humans; Hypoxia; Ion Channel Gating; Membrane Potentials; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Oxygen Consumption; Potassium Channels | 2000 |
Differential effects of K(+) channel blockers on frequency-dependent action potential broadening in supraoptic neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cadmium Chloride; Cells, Cultured; Charybdotoxin; Guinea Pigs; Male; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Supraoptic Nucleus; Tetraethylammonium | 2000 |
Cell cycle-related changes in transient K(+) current density in the GH3 pituitary cell line.
Topics: 4-Aminopyridine; Antimetabolites; Bromodeoxyuridine; Cell Division; Cell Line; Charybdotoxin; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Pituitary Gland; Potassium; Potassium Channels; S Phase; Tetraethylammonium; Thymidine; Tritium | 2000 |
Changes of the potassium currents in rat aortic smooth muscle cells during postnatal development.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aging; Animals; Aorta, Thoracic; Calcium; Calcium Channel Agonists; Charybdotoxin; Electric Conductivity; Male; Membrane Potentials; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; Norepinephrine; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Rats; Rats, Wistar; Tetraethylammonium; Vasoconstriction | 2000 |
Effects of phosphodiesterase inhibitors on hypoxic pulmonary vasoconstriction. Influence of K(+) channels and nitric oxide.
Topics: 4-Aminopyridine; Animals; Apamin; Charybdotoxin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Hypoxia; In Vitro Techniques; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Potassium Channels; Purinones; Rats; Rats, Wistar; Rolipram; Theophylline; Vasoconstriction | 2001 |
Distinct K currents result in physiologically distinct cell types in the inferior colliculus of the rat.
Topics: 4-Aminopyridine; Action Potentials; Adaptation, Physiological; Animals; Apamin; Calcium; Charybdotoxin; Electric Stimulation; In Vitro Techniques; Inferior Colliculi; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Long-Evans; Tetraethylammonium; Tetrodotoxin | 2001 |
Modulation of voltage-dependent K+ channel current in vascular smooth muscle cells from rat mesenteric arteries.
Topics: 4-Aminopyridine; Animals; Brain; Cells, Cultured; Charybdotoxin; Immunoblotting; Kinetics; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Peptides; Potassium Channels; Rats; Rats, Sprague-Dawley; Tetraethylammonium | 2001 |
Oxygen dilation in fetal pulmonary arterioles: role of K(+) channels.
Topics: 4-Aminopyridine; Animals; Arterioles; Charybdotoxin; Female; Fetus; Glyburide; Hypoglycemic Agents; Lung; Oxygen; Potassium Channel Blockers; Potassium Channels; Pregnancy; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Vasodilation | 2001 |
Relaxation to authentic nitric oxide and SIN-1 in rat isolated mesenteric arteries: variable role for smooth muscle hyperpolarization.
Topics: 4-Aminopyridine; Animals; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Membrane Potentials; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Peptides; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Vasodilation | 2001 |
Pharmacological evidence for the activation of potassium channels as the mechanism involved in the hypotensive and vasorelaxant effect of dioclein in rat small resistance arteries.
Topics: 4-Aminopyridine; Analgesics; Animals; Apamin; Barium Compounds; Charybdotoxin; Chlorides; Consciousness; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Flavanones; Flavonoids; Glyburide; Hemodynamics; Hypotension; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Rats; Rats, Wistar; Tetraethylammonium; Time Factors; Vascular Resistance; Vasodilation | 2001 |
Dibutyryl-cyclic GMP induces peripheral antinociception via activation of ATP-sensitive K(+) channels in the rat PGE2-induced hyperalgesic paw.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Analgesics; Animals; Apamin; Cesium; Charybdotoxin; Dibutyryl Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Glyburide; Hindlimb; Hyperalgesia; Male; Pain; Pain Measurement; Pain Threshold; Potassium Channels; Rats; Rats, Wistar; Tetraethylammonium; Tolbutamide | 2001 |
Inhibition of voltage-gated K(+) currents by endothelin-1 in human pulmonary arterial myocytes.
Topics: 4-Aminopyridine; Adolescent; Adult; Animals; Cells, Cultured; Charybdotoxin; Child; Endothelin-1; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Indoles; Male; Maleimides; Middle Aged; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pulmonary Artery; Staurosporine; Vasoconstriction | 2001 |
Cellular target of voltage and calcium-dependent K(+) channel blockers involved in EDHF-mediated responses in rat superior mesenteric artery.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Apamin; Biological Factors; Calcium; Calcium Signaling; Charybdotoxin; Cytosol; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Potassium; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Rats, Inbred WKY; Vasodilation; Vasodilator Agents | 2001 |
Heteromultimeric Kv1.2-Kv1.5 channels underlie 4-aminopyridine-sensitive delayed rectifier K(+) current of rabbit vascular myocytes.
Topics: 4-Aminopyridine; Animals; Cells, Cultured; Charybdotoxin; Delayed Rectifier Potassium Channels; Electric Conductivity; Kinetics; Kv1.2 Potassium Channel; Kv1.5 Potassium Channel; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Portal Vein; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Subunits; Rabbits; Transfection | 2001 |
Determinants of renal microvascular response to ACh: afferent and efferent arteriolar actions of EDHF.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Apamin; Arterioles; Barium; Biological Factors; Charybdotoxin; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Ibuprofen; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Potassium Channels, Voltage-Gated; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Renal Circulation; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2002 |
Increment of calcium-activated and delayed rectifier potassium current by hyposmotic swelling in gastric antral circular myocytes of guinea pig.
Topics: 4-Aminopyridine; Animals; Cell Separation; Charybdotoxin; Delayed Rectifier Potassium Channels; Female; Guinea Pigs; Hypotonic Solutions; Male; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Pyloric Antrum | 2001 |
Inhibitory effects of volatile anesthetics on K+ and Cl- channel currents in porcine tracheal and bronchial smooth muscle.
Topics: 4-Aminopyridine; Anesthetics, Inhalation; Animals; Bronchi; Charybdotoxin; Chloride Channels; Electrophysiology; Female; In Vitro Techniques; Isoflurane; Male; Methyl Ethers; Muscle, Smooth; Patch-Clamp Techniques; Potassium Channels; Sevoflurane; Swine; Trachea | 2002 |
Pharmacological evidence for the activation of K(+) channels by diclofenac.
Topics: 4-Aminopyridine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship, Drug; Female; Formaldehyde; Glyburide; Hindlimb; Morphine; Pain; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Tetraethylammonium; Tolbutamide | 2002 |
A potassium ion channel is involved in cytokine production by activated human macrophages.
Topics: 4-Aminopyridine; Calcium; Cells, Cultured; Charybdotoxin; Gene Expression Regulation; Humans; Interleukin-8; Ion Channel Gating; Ion Transport; Lipopolysaccharides; Macrophage Activation; Macrophages; Osmolar Concentration; Potassium; Potassium Channels; Protein Biosynthesis; Protein Processing, Post-Translational; RNA, Messenger; Sodium Selenite; Sotalol; Stress, Mechanical; Sucrose; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tumor Necrosis Factor-alpha | 2002 |
Decreased 4-aminopyridine sensitive K+ currents in endothelial cells from hypertensive rats.
Topics: 4-Aminopyridine; Animals; Aorta; Apamin; Charybdotoxin; Drug Combinations; Endothelium, Vascular; Genetic Predisposition to Disease; Hypertension; Kv1.5 Potassium Channel; Male; Membrane Potentials; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke | 2002 |
The peripheral antinociceptive effect of resveratrol is associated with activation of potassium channels.
Topics: 4-Aminopyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; ATP-Binding Cassette Transporters; Charybdotoxin; Female; Glipizide; Glyburide; KATP Channels; Morphine; Narcotics; Peripheral Nervous System; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tetraethylammonium; Tolbutamide | 2002 |
Possible involvement of potassium channels in peripheral antinociception induced by metamizol: lack of participation of ATP-sensitive K+ channels.
Topics: 4-Aminopyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Area Under Curve; ATP-Binding Cassette Transporters; Charybdotoxin; Dipyrone; Drug Interactions; Female; Formaldehyde; Glyburide; KATP Channels; Pain Measurement; Peripheral Nerves; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Tetraethylammonium; Tolbutamide | 2003 |
TGF-beta1 induces the expression of fast inactivating K+ (I(A)) channels in rat vascular myofibroblasts.
Topics: 4-Aminopyridine; Animals; Aorta, Thoracic; Cells, Cultured; Charybdotoxin; Fibroblasts; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Inbred WKY; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
An endothelium-derived factor modulates purinergic neurotransmission to mesenteric arterial smooth muscle of hamster.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Apamin; Biological Factors; Charybdotoxin; Cricetinae; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Fatty Acids, Unsaturated; Glyburide; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Mesocricetus; Muscle, Smooth, Vascular; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ouabain; Pinacidil; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Synaptic Transmission; Tetraethylammonium; Time Factors; Triazines; Uridine Triphosphate; Vasodilator Agents | 2003 |
Inhibition of EDHF by two new combinations of K+-channel inhibitors in rat isolated mesenteric arteries.
Topics: 4-Aminopyridine; Acetonitriles; Animals; Apamin; Benzimidazoles; Biological Factors; Charybdotoxin; Dose-Response Relationship, Drug; Male; Mesenteric Arteries; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Scorpion Venoms; Scorpions; Trityl Compounds | 2003 |
Voltage-gated potassium currents in rat vas deferens smooth muscle cells.
Topics: 4-Aminopyridine; Animals; Biophysical Phenomena; Biophysics; Charybdotoxin; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Drug; Electric Conductivity; Large-Conductance Calcium-Activated Potassium Channels; Male; Models, Biological; Myocytes, Smooth Muscle; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Tetraethylammonium; Vas Deferens | 2003 |
Involvement of inwardly rectifying K+ channels in secretory responses of human ileal mucosa.
Topics: 4-Aminopyridine; Apamin; Bacterial Toxins; Barium Compounds; Charybdotoxin; Chlorides; Glyburide; Humans; Ileum; Intestinal Mucosa; Potassium Channel Blockers; Potassium Channels; Vasoactive Intestinal Peptide | 2003 |
Predominant expression of Kv1.3 voltage-gated K+ channel subunit in rat prostate cancer cell lines: electrophysiological, pharmacological and molecular characterisation.
Topics: 4-Aminopyridine; Animals; Blotting, Western; Calcium Channel Blockers; Cell Line, Tumor; Charybdotoxin; Gene Expression Regulation, Neoplastic; Kv1.3 Potassium Channel; Male; Membrane Potentials; Molecular Sequence Data; Neurotoxins; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Prostatic Neoplasms; Rats; Reverse Transcriptase Polymerase Chain Reaction; Scorpion Venoms; Tetraethylammonium; Verapamil | 2003 |
Study of the involvement of K+ channels in the peripheral antinociception of the kappa-opioid receptor agonist bremazocine.
Topics: 4-Aminopyridine; Analgesics; Animals; ATP-Binding Cassette Transporters; Benzomorphans; Charybdotoxin; Cyclic GMP; Dequalinium; Glyburide; Hyperalgesia; KATP Channels; Male; Naltrexone; Nitric Oxide; Peripheral Nervous System; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Receptors, Opioid, kappa; Signal Transduction; Tetraethylammonium; Tolbutamide | 2004 |
Volume regulation of mature and immature spermatozoa in a primate model, and possible ion channels involved.
Topics: 4-Aminopyridine; Animals; Apamin; Cell Size; Cells, Cultured; Charybdotoxin; Ejaculation; Epididymis; Glyburide; Ion Channels; Macaca fascicularis; Male; Neurotoxins; Nitrobenzoates; Potassium Channel Blockers; Quaternary Ammonium Compounds; Quinine; Scorpion Venoms; Spermatozoa; Tetraethylammonium | 2004 |
Characterization of the voltage-activated currents in cultured atrial myocytes isolated from the heart of the common oyster Crassostrea gigas.
Topics: 4-Aminopyridine; Animals; Cadmium; Calcium; Cells, Cultured; Charybdotoxin; Cobalt; Electrophysiology; Heart Atria; Ion Channels; Membrane Potentials; Myocytes, Cardiac; Ostreidae; Patch-Clamp Techniques; Potassium; Sodium; Tetraethylammonium; Verapamil | 2004 |
Impaired KATP channel function in the fetoplacental circulation of patients with type 1 diabetes mellitus.
Topics: 4-Aminopyridine; Charybdotoxin; Diabetes Mellitus, Type 1; Endothelial Cells; Female; Glyburide; Humans; In Vitro Techniques; Placental Circulation; Potassium Channels; Pregnancy; Pregnancy in Diabetics | 2005 |
Nuclear factor-kappaB activation by reactive oxygen species mediates voltage-gated K+ current enhancement by neurotoxic beta-amyloid peptides in nerve growth factor-differentiated PC-12 cells and hippocampal neurones.
Topics: 4-Aminopyridine; Actin Cytoskeleton; Amyloid beta-Peptides; Animals; Blotting, Western; Calcium; Cell Differentiation; Cells, Cultured; Charybdotoxin; Chelating Agents; Cnidarian Venoms; Dactinomycin; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; GAP-43 Protein; Hippocampus; Membrane Potentials; Nerve Growth Factor; Neurons; NF-kappa B; Patch-Clamp Techniques; PC12 Cells; Peptide Fragments; Peptides; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Synthesis Inhibitors; Rats; Reactive Oxygen Species; Tetraethylammonium; Time Factors; Vitamin A | 2005 |
Pharmacological evidence for the activation of Ca2+-activated K+ channels by meloxicam in the formalin test.
Topics: 4-Aminopyridine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Apamin; Behavior, Animal; Charybdotoxin; Dose-Response Relationship, Drug; Female; Formaldehyde; Glyburide; Meloxicam; Pain; Pain Measurement; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Tetraethylammonium; Thiazines; Thiazoles; Tolbutamide | 2005 |
Ca2+-activated K+-current density is correlated with soma size in rat vestibular-afferent neurons in culture.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Apamin; Calcium; Cell Size; Cells, Cultured; Charybdotoxin; Clotrimazole; Dose-Response Relationship, Radiation; Drug Interactions; Electric Capacitance; Electric Stimulation; Membrane Potentials; Neurons, Afferent; Neurotoxins; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Tetraethylammonium; Tetrodotoxin; Vestibule, Labyrinth | 2005 |
Capsaicin-induced, capsazepine-insensitive relaxation of the guinea-pig ileum.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Apamin; Barium; Benzopyrans; Caffeine; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Charybdotoxin; Diclofenac; Dimethyl Sulfoxide; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Guanethidine; Guinea Pigs; Ileum; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Relaxation; Muscle, Smooth; Myosin Light Chains; Nitroarginine; Papaverine; Peptide Fragments; Phosphodiesterase Inhibitors; Phosphorylation; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Protein Serine-Threonine Kinases; Pyrazoles; Receptor, Cannabinoid, CB1; rho-Associated Kinases; Tetraethylammonium; Vasodilator Agents | 2006 |
Possible activation of the NO-cyclic GMP-protein kinase G-K+ channels pathway by gabapentin on the formalin test.
Topics: 4-Aminopyridine; Amines; Analgesics; Animals; Apamin; Carbazoles; Charybdotoxin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Indoles; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Tolbutamide | 2006 |
The mechanism of endothelium-independent relaxation induced by the wine polyphenol resveratrol in human internal mammary artery.
Topics: 4-Aminopyridine; Anti-Arrhythmia Agents; Charybdotoxin; Coronary Artery Bypass; Coronary Disease; Glyburide; Humans; Male; Mammary Arteries; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Neurotoxins; Potassium Channel Blockers; Potassium Channels; Resveratrol; Scorpion Venoms; Stilbenes; Tetraethylammonium; Vasodilation; Vasodilator Agents; Wine | 2006 |
Potassium channels-mediated vasorelaxation of rat aorta induced by resveratrol.
Topics: 4-Aminopyridine; Animals; Antioxidants; Aorta; Charybdotoxin; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Glyburide; In Vitro Techniques; Male; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Resveratrol; Scorpion Venoms; Stilbenes; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2006 |
Functional characterization of voltage-gated K+ channels in mouse pulmonary artery smooth muscle cells.
Topics: 4-Aminopyridine; Animals; Cells, Cultured; Charybdotoxin; Ion Channel Gating; Membrane Potentials; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neurotoxins; Patch-Clamp Techniques; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pulmonary Artery; Tetraethylammonium | 2007 |
Role of K(+) channels in the regulation of electrical spontaneous activity of the mouse small intestine.
Topics: 4-Aminopyridine; Animals; Apamin; Charybdotoxin; Electrophysiology; Female; Ileum; Male; Mice; Mice, Inbred BALB C; Nifedipine; Peptides; Phenylephrine; Potassium Channels; Potassium Channels, Calcium-Activated; Tetrodotoxin | 2007 |
The gender differences in the relaxation to levosimendan of human internal mammary artery.
Topics: 4-Aminopyridine; Anti-Arrhythmia Agents; Charybdotoxin; Coronary Artery Bypass; Dose-Response Relationship, Drug; Female; Glyburide; Humans; Hydrazones; Male; Mammary Arteries; Middle Aged; Potassium Channel Blockers; Pyridazines; Sex Characteristics; Simendan; Vasodilation | 2007 |
Calcitonin gene-related peptide inhibits angiotensin II-mediated vasoconstriction in human radial arteries: role of the Kir channel.
Topics: 4-Aminopyridine; Aged; Angiotensin II; Apamin; Barium; Calcitonin Gene-Related Peptide; Charybdotoxin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; In Vitro Techniques; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channel Blockers; Potassium Channels; Radial Artery; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Endothelium-independent vasodilation induced by kolaviron, a biflavonoid complex from Garcinia kola seeds, in rat superior mesenteric arteries.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channels, L-Type; Charybdotoxin; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Flavonoids; Garcinia kola; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Mesenteric Artery, Superior; Muscle Contraction; Neurotoxins; Organ Culture Techniques; Phenylephrine; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Wistar; Seeds; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
Characterisation of K+ currents in the C8-B4 microglial cell line and their regulation by microglia activating stimuli.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Animals; Apamin; Barium; Calcium; Cations; Cell Line; Charybdotoxin; Dose-Response Relationship, Drug; Drug Combinations; Elapid Venoms; Electrodes; Electrophysiology; Fluorescent Antibody Technique, Direct; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Interferon-gamma; Lipopolysaccharides; Membrane Potentials; Mice; Mice, Inbred C57BL; Microglia; Neurotoxins; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyrazoles; Scorpion Venoms; Transforming Growth Factor beta | 2009 |
Action potential bursts in central snail neurons elicited by paeonol: roles of ionic currents.
Topics: 4-Aminopyridine; Acetophenones; Action Potentials; Animals; Calcium; Carbazoles; Charybdotoxin; Electric Conductivity; Indoles; Ion Channels; Nervous System Physiological Phenomena; Neurons; Potassium; Pyrroles; Reaction Time; Snails; Tetraethylammonium | 2010 |
Suppression of a neocortical potassium channel activity by intracellular amyloid-β and its rescue with Homer1a.
Topics: 4-Aminopyridine; Action Potentials; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Carboxylic Acids; Carrier Proteins; Charybdotoxin; Electroshock; Enzyme Inhibitors; Female; Gene Expression Regulation; Homer Scaffolding Proteins; In Vitro Techniques; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Neural Inhibition; Neurons; Nimodipine; Patch-Clamp Techniques; Peptide Fragments; Phenanthrenes; Potassium Channel Blockers; Potassium Channels; Presenilin-1; Rats; tau Proteins | 2011 |
Involvement of presynaptic voltage-dependent Kv3 channel in endothelin-1-induced inhibition of noradrenaline release from rat gastric sympathetic nerves.
Topics: 4-Aminopyridine; Animals; Apamin; Basal Metabolism; Charybdotoxin; Elapid Venoms; Electric Stimulation; Endothelin-1; Estrenes; In Vitro Techniques; Male; Norepinephrine; Phospholipid Ethers; Pyrrolidinones; Rats; Rats, Wistar; Shaw Potassium Channels; Stomach; Sympathetic Nervous System; Synapses | 2012 |
Effects of glucagon-like peptide-1 in diabetic rat small resistance arteries.
Topics: 4-Aminopyridine; Animals; Apamin; Arteries; Charybdotoxin; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Glucagon-Like Peptide 1; Glyburide; Male; Nitric Oxide; Peptide Fragments; Peptides; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2014 |
Na+K+-ATPase activity and K+ channels differently contribute to vascular relaxation in male and female rats.
Topics: 4-Aminopyridine; Animals; Apamin; Charybdotoxin; Female; Male; NG-Nitroarginine Methyl Ester; Potassium Channel Blockers; Potassium Channels; Rats; Sex Factors; Sodium-Potassium-Exchanging ATPase; Tetraethylammonium; Vasodilation | 2014 |