4-aminopyridine has been researched along with acetazolamide in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bencsik, K; Mihály, A; Nógrádi, A | 1 |
| Ikeda, M; Kadoi, J; Matsumoto, S; Nishikawa, T; Saiki, C; Takeda, M; Tanimoto, T; Yoshida, S | 1 |
| Brandt, T; Dichgans, M; Freilinger, T; Glasauer, S; Kalla, R; Strupp, M | 1 |
| Aoba, T; Ikeda, M; Matsumoto, S; Nasu, M; Saiki, C; Shimazu, Y; Suzuki, K; Takeda, M; Tanimoto, T; Yoshida, S | 1 |
| Brandt, T; Strupp, M; Zwergal, A | 1 |
| Ikeda, M; Kadoi, J; Kitagawa, J; Matsumoto, S; Saiki, C; Shima, Y; Takahashi, M; Takeda, M; Tanimoto, T; Yoshida, S | 1 |
| Kramer, MA; Lillis, KP; Mertz, J; Staley, KJ; White, JA | 1 |
| Abbasi, A; Abbasi, S; Sarbaz, Y | 2 |
| Carter, RE; Chen, G; Cramer, SW; Ebner, TJ; Popa, LS | 1 |
| Avoli, M; Hamidi, S | 1 |
| Brieva-Ruiz, L; González-Mingot, C; López-Ortega, R | 1 |
1 review(s) available for 4-aminopyridine and acetazolamide
| Article | Year |
|---|---|
Episodic ataxia type 2.
Topics: 4-Aminopyridine; Acetazolamide; Animals; Calcium Channels; Carbonic Anhydrase Inhibitors; Cerebellar Ataxia; Disease Models, Animal; Humans; Mutation; Potassium Channel Blockers | 2007 |
1 trial(s) available for 4-aminopyridine and acetazolamide
| Article | Year |
|---|---|
Treatment of episodic ataxia type 2 with the potassium channel blocker 4-aminopyridine.
Topics: 4-Aminopyridine; Acetazolamide; Adolescent; Adult; Ataxia; Calcium Channels; Humans; Male; Middle Aged; Mutation; Nystagmus, Pathologic; Potassium Channel Blockers; Purkinje Cells; Treatment Outcome | 2004 |
12 other study(ies) available for 4-aminopyridine and acetazolamide
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Pharmacological inhibition of brain carbonic anhydrase protects against 4-aminopyridine seizures.
Topics: 4-Aminopyridine; Acetazolamide; Animals; Brain; Brain Chemistry; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Histocytochemistry; Male; Rats; Rats, Inbred Strains; Seizures | 1994 |
Effects of acetazolamide and 4-aminoprydine on the responses of deflationary slowly adapting pulmonary stretch receptors to CO2 inhalation in the rat.
Topics: 4-Aminopyridine; Acetazolamide; Adaptation, Physiological; Administration, Inhalation; Animals; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Electrophysiology; Hydrogen-Ion Concentration; Kinetics; Potassium Channel Blockers; Pulmonary Stretch Receptors; Rats; Rats, Wistar; Respiratory Mechanics; Structure-Activity Relationship; Vagotomy | 2003 |
Effects of acetazolamide and 4-aminopyridine on CO2-induced slowly adapting pulmonary stretch receptor inhibition in rats.
Topics: 4-Aminopyridine; Acetazolamide; Administration, Inhalation; Animals; Carbon Dioxide; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Myocytes, Smooth Muscle; Potassium Channel Blockers; Pulmonary Stretch Receptors; Rats; Trachea | 2004 |
Effects of acetazolamide on transient K+ currents and action potentials in nodose ganglion neurons of adult rats.
Topics: 4-Aminopyridine; Acetazolamide; Action Potentials; Animals; Carbonic Anhydrase Inhibitors; Cells, Cultured; Drug Interactions; Male; Neurons; Nodose Ganglion; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Subunits; Rats; Rats, Wistar | 2011 |
Pyramidal cells accumulate chloride at seizure onset.
Topics: 4-Aminopyridine; Acetazolamide; Animals; Animals, Newborn; Anticonvulsants; Chlorides; Dose-Response Relationship, Drug; Evoked Potentials; GABA Agents; Glutamate Decarboxylase; Green Fluorescent Proteins; Hippocampus; Hydrogen-Ion Concentration; Interneurons; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Organ Culture Techniques; Potassium Channel Blockers; Pyramidal Cells; Recombinant Fusion Proteins | 2012 |
Combination of BK channel opener and Kv4 channel inhibitor for treatment of cerebellar ataxia in mutant med mice.
Topics: 4-Aminopyridine; Acetazolamide; Animals; Cerebellar Ataxia; Large-Conductance Calcium-Activated Potassium Channels; Mice; Mice, Neurologic Mutants; NAV1.6 Voltage-Gated Sodium Channel; Potassium Channel Blockers | 2013 |
Introducing treatment strategy for cerebellar ataxia in mutant med mice: combination of acetazolamide and 4-aminopyridine.
Topics: 4-Aminopyridine; Acetazolamide; Action Potentials; Animals; Cerebellar Ataxia; Disease Models, Animal; Drug Therapy, Combination; Mice; Mice, Mutant Strains; Neuroprotective Agents; Purkinje Cells | 2014 |
Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.
Topics: 4-Aminopyridine; Acetazolamide; Animals; Benzeneacetamides; Calcium Channels, N-Type; Cerebral Cortex; Channelopathies; Cortical Synchronization; Disease Models, Animal; Enzyme Inhibitors; Female; Male; Mice; Mice, Transgenic; Mutation; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Potassium Channel Blockers; Pyridines; Quinoxalines; Vibrissae | 2015 |
Carbonic anhydrase inhibition by acetazolamide reduces in vitro epileptiform synchronization.
Topics: 4-Aminopyridine; Acetazolamide; Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cerebral Cortex; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Male; Microelectrodes; Period Circadian Proteins; Rats, Sprague-Dawley; Tissue Culture Techniques; Xenopus Proteins | 2015 |
The efficacy of combining topiramate and 4-aminopyridine to reduce relapses and interictal progression in two cases of episodic ataxia type 2.
Topics: 4-Aminopyridine; Acetazolamide; Adult; Ataxia; Cerebellar Ataxia; Female; Humans; Male; Middle Aged; Migraine Disorders; Mutation; Nystagmus, Pathologic; Recurrence; Topiramate; Vertigo | 2022 |