4-aminopyridine and 6-cyano-7-nitroquinoxaline-2,3-dione

4-aminopyridine has been researched along with 6-cyano-7-nitroquinoxaline-2,3-dione in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's31 (45.59)18.2507
2000's28 (41.18)29.6817
2010's8 (11.76)24.3611
2020's1 (1.47)2.80

Authors

AuthorsStudies
Avoli, M; Psarropoulou, C2
Banks, MI; Smith, PH1
Bijak, M; Brunner, H; Dembowsky, K; Misgeld, U1
Aram, JA; Michelson, HB; Wong, RK1
Kessler, M; Lynch, G; Staubli, U; Xiao, P1
Gean, PW1
Chang, FC; Chou, SM; Gean, PW1
Jahr, CE; Tong, G1
Boos, R; Schneider, H; Wässle, H1
Avoli, M; Mattia, D; Perreault, P; Siniscalchi, A; Tomaiuolo, F1
Avoli, M; Fueta, Y; Psarropoulou, C; Tancredi, V1
Bijak, M; Misgeld, U1
Avoli, M; Kurcewicz, I; Louvel, J; Pumain, R1
Lev-Tov, A; Pinco, M1
Avoli, M; Hwa, GG; Mattia, D1
Bijak, M; Demmelhuber, J; Jarolimek, W; Misgeld, U1
Avoli, M; Barbarosie, M; Köhling, R; Lopantsev, V; Lücke, A; Nagao, T1
Avoli, M; Lopantsev, V3
Avoli, M; Barbarosie, M; Kurcewicz, I; Louvel, J; Pumain, R1
Avoli, M; Köhling, R; Lücke, A; Nagao, T; Speckmann, EJ1
Malenka, RC; Nicoll, RA; Salin, PA; Scanziani, M1
Avoli, M; Barbarosie, M; Köhling, R1
Bernardi, G; Calabresi, P; Mercuri, NB; Siniscalchi, A1
Ayala, GX; Bargas, J; Galarraga, E; Hernández, E1
Avoli, M; Kawasaki, H; Methot, M1
Albuquerque, EX; Braga, MF; Pereira, EF1
Batini, C; Vigot, R1
Avoli, M; Bernasconi, A; Hwa, GG; Mattia, D; Olivier, A1
Avoli, M; Barbarosie, M; Calcagnotto, ME1
Ben-Ari, Y; Dzhala, VI; Luhmann, HJ1
de Groat, WC; Kawatani, M; Miura, A1
Irnaten, M; Mendelowitz, D; Wang, J1
Michelson, HB; Yang, Q1
Saggau, P; Sinha, SR1
Häusser, M; Roth, A1
Barrionuevo, G; González-Burgos, G1
Bergevin, A; Congar, P; Trudeau, LE1
Benardo, LS; Yang, L1
Avoli, M; Barbarosie, M; D'Antuono, M; Kurcewicz, I; Louvel, J1
Avoli, M; Benini, R; de Guzman, P; Omar, A1
Nistri, A; Taccola, G1
Barrionuevo, G; Grace, AA; Kröner, S; Rosenkranz, JA1
Akaike, T; Murai, Y1
Jiang, L; Kang, J; Kang, N; Nedergaard, M; Xu, J1
Araque, A; Perea, G1
DeFazio, RA; Hablitz, JJ1
Asl, MN; Carlen, PL; Wong, T; Wu, CP; Zhang, L; Zhang, XL1
Inoue, M; Kudo, Y; Miyakawa, H; Miyazaki, K; Murayama, M1
Kang, J; Kang, N; Nedergaard, M; Xu, J; Xu, Q1
Errington, AC; Lees, G; Stöhr, T1
Andreasen, M; Nedergaard, S; Skov, J2
Chen, Q; Pan, HL1
Haji, A; Kato, F; Ohi, Y1
Ben-Ari, Y; Represa, A; Rheims, S; Zilberter, Y1
Avoli, M; Colosimo, A; Cruccu, G; Curia, G; Panuccio, G1
Kilb, W; Luhmann, HJ; Richter, D1
Bateman, RJ; Mendelowitz, D; Philbin, KE1
Canning, BJ; Mori, N1
Chang, WP; Lee, CM; Shyu, BC; Vogt, BA; Wu, JS1
Akaike, N; Maeda, M; Mizuno, Y; Nonaka, K; Shin, MC; Shoudai, K; Wakita, M; Yamaga, T1
Avoli, M; Hamidi, S1
Agudelo-Toro, A; Moses, E; Neef, A; Rotem, A; Stern, S1
Avoli, M; Benini, R; D'Antuono, M; de Guzman, P; Köhling, R1
Chuang, AY; Chuang, HH; Huang, CS; Lai, YC; Wang, GH; Yang, YC; Yeh, JY1

Other Studies

68 other study(ies) available for 4-aminopyridine and 6-cyano-7-nitroquinoxaline-2,3-dione

ArticleYear
CPP, an NMDA-receptor antagonist, blocks 4-aminopyridine-induced spreading depression episodes but not epileptiform activity in immature rat hippocampal slices.
    Neuroscience letters, 1992, Jan-20, Volume: 135, Issue:1

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Anticonvulsants; Dendrites; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; Models, Biological; Piperazines; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate

1992
Intracellular recordings from neurobiotin-labeled cells in brain slices of the rat medial nucleus of the trapezoid body.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:7

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Bicuculline; Biotin; Cochlear Nerve; Electric Conductivity; In Vitro Techniques; Male; Membrane Potentials; Nerve Fibers; Neurons; Pons; Quinoxalines; Rats; Rats, Inbred Strains; Strychnine

1992
K-dependent inhibition in the dentate-CA3 network of guinea pig hippocampal slices.
    Journal of neurophysiology, 1992, Volume: 68, Issue:5

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Cytoplasmic Granules; Guinea Pigs; Hippocampus; Histocytochemistry; Horseradish Peroxidase; In Vitro Techniques; Membrane Potentials; Nerve Net; Neurons; Potassium; Quinoxalines; Synaptic Transmission

1992
Synchronized GABAergic IPSPs recorded in the neocortex after blockade of synaptic transmission mediated by excitatory amino acids.
    Journal of neurophysiology, 1991, Volume: 65, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Picrotoxin; Quinoxalines; Synapses; Synaptic Transmission

1991
Selective effects of aniracetam across receptor types and forms of synaptic facilitation in hippocampus.
    Hippocampus, 1991, Volume: 1, Issue:4

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Hippocampus; Hydroxybenzoate Ethers; Hydroxybenzoates; Long-Term Potentiation; Pyrrolidines; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship; Synaptic Transmission

1991
The epileptiform activity induced by 4-aminopyridine in rat amygdala slices: antagonism by non-N-methyl-D-aspartate receptor antagonists.
    Brain research, 1990, Oct-22, Volume: 530, Issue:2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Electrophysiology; Epilepsy; In Vitro Techniques; Male; Membrane Potentials; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate

1990
Epileptiform activity induced by 4-aminopyridine in rat amygdala neurons: the involvement of N-methyl-D-aspartate receptors.
    European journal of pharmacology, 1990, Aug-10, Volume: 184, Issue:2-3

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Calcium; Electric Stimulation; Epilepsy; Evoked Potentials; In Vitro Techniques; Male; Membrane Potentials; Microelectrodes; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate

1990
Multivesicular release from excitatory synapses of cultured hippocampal neurons.
    Neuron, 1994, Volume: 12, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Electric Stimulation; Evoked Potentials; Hippocampus; N-Methylaspartate; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses

1994
Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:7

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cobalt; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium Channels; Quinoxalines; Rats; Receptors, Amino Acid; Retina; Retinal Ganglion Cells; Sodium Channels; Strychnine; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin

1993
Pharmacology and electrophysiology of a synchronous GABA-mediated potential in the human neocortex.
    Neuroscience, 1994, Volume: 62, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Humans; Male; Piperazines; Tetrodotoxin

1994
On the synchronous activity induced by 4-aminopyridine in the CA3 subfield of juvenile rat hippocampus.
    Journal of neurophysiology, 1993, Volume: 70, Issue:3

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Culture Techniques; Evoked Potentials; Hippocampus; Neuroglia; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA; Synaptic Transmission

1993
Role of glutamatergic synaptic transmission in synchronized discharges of hilar neurons in guinea pig hippocampal slices.
    Neuroscience letters, 1993, Dec-12, Volume: 163, Issue:2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurons; Picrotoxin; Quinoxalines; Receptors, GABA-B; Receptors, Glutamate; Synaptic Transmission; Time Factors

1993
Extracellular free potassium during synchronous activity induced by 4-aminopyridine in the juvenile rat hippocampus.
    Neuroscience letters, 1994, Feb-14, Volume: 167, Issue:1-2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Electrophysiology; Extracellular Space; Hippocampus; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors

1994
4-Aminopyridine-induced spreading depression episodes in immature hippocampus: developmental and pharmacological characteristics.
    Neuroscience, 1993, Volume: 55, Issue:1

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cortical Spreading Depression; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate

1993
Synaptic excitation of alpha-motoneurons by dorsal root afferents in the neonatal rat spinal cord.
    Journal of neurophysiology, 1993, Volume: 70, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Animals, Newborn; Ganglia, Spinal; Membrane Potentials; Motor Neurons; Quinoxalines; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission

1993
Epileptiform activity induced by 4-aminopyridine in guinea-pig and rat neocortices.
    Neuroscience letters, 1993, May-14, Volume: 154, Issue:1-2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Cerebral Cortex; Electric Stimulation; Electrophysiology; Epilepsy; Guinea Pigs; In Vitro Techniques; Piperazines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate

1993
CGP 55845A blocks baclofen, gamma-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons.
    Neuroscience letters, 1993, May-14, Volume: 154, Issue:1-2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Potassium Channels; Quinoxalines; Synapses

1993
Synchronous GABA-mediated potentials and epileptiform discharges in the rat limbic system in vitro.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Jun-15, Volume: 16, Issue:12

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Animals; Disease Models, Animal; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Limbic System; Male; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin Receptor Agonists

1996
Reverberation of chloride-dependent synaptic potentials in the rat entorhinal cortex in vitro.
    Neuroscience letters, 1996, May-24, Volume: 210, Issue:1

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chloride Channels; Chlorides; Electrophysiology; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; N-Methylaspartate; Periodicity; Rats; Rats, Sprague-Dawley; Synaptic Transmission

1996
Extracellular free potassium and calcium during synchronous activity induced by 4-aminopyridine in the juvenile rat hippocampus.
    The Journal of physiology, 1996, Jun-15, Volume: 493 ( Pt 3)

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Analgesics; Animals; Calcium; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Extracellular Space; Hippocampus; Membrane Potentials; Patch-Clamp Techniques; Piperazines; Potassium; Rats; Receptors, Opioid, mu

1996
Extracellular potassium elevations in the hippocampus of rats with long-term pilocarpine seizures.
    Neuroscience letters, 1995, Dec-01, Volume: 201, Issue:1

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Hippocampus; In Vitro Techniques; Male; Muscarinic Agonists; Pilocarpine; Piperazines; Potassium; Rats; Seizures

1995
Distinct short-term plasticity at two excitatory synapses in the hippocampus.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Nov-12, Volume: 93, Issue:23

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Egtazic Acid; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Magnesium; Nerve Fibers; Neuronal Plasticity; Neurons; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors

1996
Anoxia blocks the presynaptic control of GABA release at inhibitory terminals in the rat hippocampus.
    Neuroscience, 1996, Volume: 75, Issue:4

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Animals; Baclofen; Cell Hypoxia; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Male; Neurons; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission

1996
Epileptiform discharge induced by 4-aminopyridine in magnesium-free medium in neocortical neurons: physiological and pharmacological characterization.
    Neuroscience, 1997, Volume: 81, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Culture Media; Dendrites; Dopamine; Epilepsy; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Magnesium; Male; Membrane Potentials; Neocortex; Neurons; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate

1997
Participation of GABAA-mediated inhibition in ictallike discharges in the rat entorhinal cortex.
    Journal of neurophysiology, 1998, Volume: 79, Issue:1

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Neurons; Potassium Acetate; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

1998
Ca2+-channels involved in neostriatal glutamatergic transmission.
    Brain research bulletin, 1998, Mar-15, Volume: 45, Issue:5

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Magnesium; Neostriatum; Rats; Rats, Wistar; Synapses; Synaptic Transmission

1998
Laminar organization of epileptiform discharges in the rat entorhinal cortex in vitro.
    The Journal of physiology, 1998, Jun-15, Volume: 509 ( Pt 3)

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Calcium; Electrophysiology; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Male; Neurons; Organ Culture Techniques; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

1998
GABA-dependent generation of ectopic action potentials in the rat hippocampus.
    The European journal of neuroscience, 1998, Volume: 10, Issue:8

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Piperazines; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Time Factors

1998
Nanomolar concentrations of lead inhibit glutamatergic and GABAergic transmission in hippocampal neurons.
    Brain research, 1999, Apr-24, Volume: 826, Issue:1

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Edetic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kinetics; Lead; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Channels; Sodium Channels; Synaptic Transmission; Tetrodotoxin

1999
Purkinje cell inhibitory responses to 3-APPA (3-aminopropylphosphinic acid) in RAT cerebellar slices.
    Neuroscience research, 1999, Volume: 34, Issue:3

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Cerebellum; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Purkinje Cells; Rats; Rats, Sprague-Dawley; Tetrodotoxin

1999
Epileptiform discharges in the human dysplastic neocortex: in vitro physiology and pharmacology.
    Annals of neurology, 1999, Volume: 46, Issue:6

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; Anticonvulsants; Cerebral Cortex; Child; Electroencephalography; Epilepsies, Partial; Epilepsy, Frontal Lobe; Epilepsy, Temporal Lobe; Evoked Potentials; Female; Humans; In Vitro Techniques; Magnetic Resonance Imaging; Male; Membrane Potentials; Piperazines

1999
Hippocampus-entorhinal cortex loop and seizure generation in the young rodent limbic system.
    Journal of neurophysiology, 2000, Volume: 83, Issue:5

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Limbic System; Membrane Potentials; Mice; Mice, Inbred BALB C; Perforant Pathway; Piperazines; Receptors, N-Methyl-D-Aspartate; Seizures

2000
Generation and propagation of 4-AP-induced epileptiform activity in neonatal intact limbic structures in vitro.
    The European journal of neuroscience, 2000, Volume: 12, Issue:8

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Animals, Newborn; Benzoates; Dizocilpine Maleate; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Glutamate

2000
Effects of pituitary adenylate cyclase activating polypeptide on lumbosacral preganglionic neurons in the neonatal rat spinal cord.
    Brain research, 2001, Mar-23, Volume: 895, Issue:1-2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amidines; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA Antagonists; Glycine Agents; Lumbar Vertebrae; Neurons; Neuropeptides; Parasympathetic Nervous System; Patch-Clamp Techniques; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sacrum; Spinal Cord; Strychnine; Valine

2001
Firing properties of identified superior laryngeal neurons in the nucleus ambiguus in the rat.
    Neuroscience letters, 2001, Apr-27, Volume: 303, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Excitatory Amino Acid Antagonists; Laryngeal Nerves; Rats; Synaptic Transmission; Tetrodotoxin

2001
Gap junctions synchronize the firing of inhibitory interneurons in guinea pig hippocampus.
    Brain research, 2001, Jul-13, Volume: 907, Issue:1-2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Carbenoxolone; Convulsants; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gap Junctions; Guinea Pigs; Hippocampus; Interneurons; Piperazines; Pyramidal Cells; Receptors, AMPA; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

2001
Imaging of 4-AP-induced, GABA(A)-dependent spontaneous synchronized activity mediated by the hippocampal interneuron network.
    Journal of neurophysiology, 2001, Volume: 86, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Guinea Pigs; Hippocampus; Interneurons; Neural Pathways; Organ Culture Techniques; Picrotoxin; Receptors, GABA-A

2001
Compartmental models of rat cerebellar Purkinje cells based on simultaneous somatic and dendritic patch-clamp recordings.
    The Journal of physiology, 2001, Sep-01, Volume: 535, Issue:Pt 2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cadmium Chloride; Cations; Cell Compartmentation; Cell Size; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Purkinje Cells; Pyridazines; Rats; Rats, Wistar; Tetraethylammonium; Tetrodotoxin

2001
Voltage-gated sodium channels shape subthreshold EPSPs in layer 5 pyramidal neurons from rat prefrontal cortex.
    Journal of neurophysiology, 2001, Volume: 86, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Cadmium; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Ion Channel Gating; Lidocaine; Male; Nickel; Organ Culture Techniques; Potassium Channel Blockers; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Channels; Synapses; Tetraethylammonium; Tetrodotoxin

2001
D2 receptors inhibit the secretory process downstream from calcium influx in dopaminergic neurons: implication of K+ channels.
    Journal of neurophysiology, 2002, Volume: 87, Issue:2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Barium; Cadmium; Calcium; Calcium Channels; Cells, Cultured; Dopamine; Dopamine Agonists; Dopamine Antagonists; Elapid Venoms; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Ionomycin; Ionophores; Neurons; Potassium Channel Blockers; Potassium Channels; Quinpirole; Rats; Receptors, Dopamine D2; Receptors, Presynaptic; Sulpiride; Ventral Tegmental Area

2002
Laminar properties of 4-aminopyridine-induced synchronous network activities in rat neocortex.
    Neuroscience, 2002, Volume: 111, Issue:2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Intracellular Membranes; Neocortex; Nerve Net; Picrotoxin; Piperazines; Rats; Rats, Sprague-Dawley

2002
Masking synchronous GABA-mediated potentials controls limbic seizures.
    Epilepsia, 2002, Volume: 43, Issue:12

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Culture Techniques; Electroencephalography; Entorhinal Cortex; Epilepsies, Partial; Kynurenic Acid; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Nerve Net; Neural Inhibition; Neurons; Potassium Channels; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

2002
GABA(B) receptor activation and limbic network ictogenesis.
    Neuropharmacology, 2004, Volume: 46, Issue:1

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Denervation; Dose-Response Relationship, Drug; Entorhinal Cortex; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Hippocampus; In Vitro Techniques; Nerve Net; Neural Inhibition; Organophosphorus Compounds; Perforant Pathway; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Time Factors

2004
Low micromolar concentrations of 4-aminopyridine facilitate fictive locomotion expressed by the rat spinal cord in vitro.
    Neuroscience, 2004, Volume: 126, Issue:2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Locomotion; N-Methylaspartate; Nerve Net; Rats; Rats, Wistar; Spinal Cord

2004
Dopamine modulates excitability of basolateral amygdala neurons in vitro.
    Journal of neurophysiology, 2005, Volume: 93, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amygdala; Anesthetics, Local; Animals; Animals, Newborn; Benzazepines; Dopamine; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; Elapid Venoms; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Neurons; Neurons, Afferent; Patch-Clamp Techniques; Potassium Channel Blockers; Quinpirole; Rats; Staining and Labeling; Sulpiride; Synaptic Transmission; Tetrodotoxin

2005
Orexins cause depolarization via nonselective cationic and K+ channels in isolated locus coeruleus neurons.
    Neuroscience research, 2005, Volume: 51, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Intracellular Signaling Peptides and Proteins; Ion Channels; Locus Coeruleus; Membrane Potentials; Neurons; Neuropeptides; Orexins; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin

2005
Activity-dependent long-term potentiation of intrinsic excitability in hippocampal CA1 pyramidal neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Feb-16, Volume: 25, Issue:7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anisomycin; Bicuculline; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Egtazic Acid; Emetine; Excitatory Amino Acid Antagonists; Learning; Long-Term Potentiation; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channels; Propanolamines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channels

2005
Properties of synaptically evoked astrocyte calcium signal reveal synaptic information processing by astrocytes.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Mar-02, Volume: 25, Issue:9

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Aniline Compounds; Animals; Animals, Newborn; Astrocytes; Atropine; Calcium; Calcium Signaling; Cell Communication; Diagnostic Imaging; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glutamic Acid; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Muscarinic Antagonists; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Tetrodotoxin; Xanthenes

2005
Horizontal spread of activity in neocortical inhibitory networks.
    Brain research. Developmental brain research, 2005, Jun-09, Volume: 157, Issue:1

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Evoked Potentials; Excitatory Amino Acid Antagonists; Fluorescent Dyes; gamma-Aminobutyric Acid; In Vitro Techniques; Kynurenic Acid; Linear Models; Neocortex; Nerve Net; Neural Inhibition; Potassium Channel Blockers; Pyridinium Compounds; Rats; Reaction Time; Time Factors

2005
Postnatal development of intrinsic GABAergic rhythms in mouse hippocampus.
    Neuroscience, 2005, Volume: 134, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Periodicity; Potassium Channel Blockers

2005
Optical monitoring of progressive synchronization in dentate granule cells during population burst activities.
    The European journal of neuroscience, 2005, Volume: 21, Issue:12

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Calcium; Carboxylic Acids; Cell Count; Dentate Gyrus; Diagnostic Imaging; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Membrane Potentials; Monitoring, Physiologic; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Rats; Rats, Wistar; Reaction Time

2005
Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons.
    Journal of neurophysiology, 2005, Volume: 94, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Calcium; Diagnostic Imaging; Drug Interactions; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Microscopy, Confocal; Neurons; Neurotoxins; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetanus Toxin; Tetrodotoxin; Time Factors

2005
Stereoselective effects of the novel anticonvulsant lacosamide against 4-AP induced epileptiform activity in rat visual cortex in vitro.
    Neuropharmacology, 2006, Volume: 50, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetamides; Animals; Anticonvulsants; Carbamazepine; Convulsants; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Space; Female; In Vitro Techniques; Lacosamide; Male; Membrane Potentials; Patch-Clamp Techniques; Phenobarbital; Picrotoxin; Potassium Channel Blockers; Prohibitins; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Visual Cortex

2006
Postnatal development of a new type of epileptiform activity in the rat hippocampus.
    Brain research, 2006, Jun-22, Volume: 1096, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Cesium; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Receptors, Glutamate; Sodium-Potassium-Exchanging ATPase

2006
Regulation of synaptic input to hypothalamic presympathetic neurons by GABA(B) receptors.
    Neuroscience, 2006, Oct-13, Volume: 142, Issue:2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Benzylamines; Bicuculline; Cadmium Chloride; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, GABA-B

2006
Codeine presynaptically inhibits the glutamatergic synaptic transmission in the nucleus tractus solitarius of the guinea pig.
    Neuroscience, 2007, May-25, Volume: 146, Issue:3

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Codeine; Data Interpretation, Statistical; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Guinea Pigs; Male; Membrane Potentials; Naloxone; Narcotic Antagonists; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Receptors, AMPA; Receptors, Presynaptic; Solitary Nucleus; Synaptic Transmission

2007
Inwardly rectifying K(+) (Kir) channels antagonize ictal-like epileptiform activity in area CA1 of the rat hippocampus.
    Hippocampus, 2007, Volume: 17, Issue:11

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Barium; Cesium; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuroglia; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Seizures; Synaptic Transmission

2007
Layer-specific generation and propagation of seizures in slices of developing neocortex: role of excitatory GABAergic synapses.
    Journal of neurophysiology, 2008, Volume: 100, Issue:2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Animals, Newborn; Bumetanide; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Mice; Neocortex; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Potassium Channel Blockers; Reaction Time; Seizures; Sodium Potassium Chloride Symporter Inhibitors; Synapses; Synaptic Transmission

2008
Epileptiform synchronization in the cingulate cortex.
    Epilepsia, 2009, Volume: 50, Issue:3

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Cortical Synchronization; Electroencephalography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Epilepsies, Partial; Evoked Potentials; GABA Antagonists; Gyrus Cinguli; In Vitro Techniques; Male; Membrane Potentials; Neural Inhibition; Neurons; Piperazines; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, GABA-B; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, mu; Synaptic Transmission

2009
Intrinsic activation of GABA(A) receptors suppresses epileptiform activity in the cerebral cortex of immature mice.
    Epilepsia, 2010, Volume: 51, Issue:8

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Anisoles; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; In Vitro Techniques; Magnesium; Mice; Mice, Inbred C57BL; Nipecotic Acids; Patch-Clamp Techniques; Potassium Channel Blockers; Pyridazines; Receptors, GABA-A; Tiagabine

2010
Clonidine, an alpha2-receptor agonist, diminishes GABAergic neurotransmission to cardiac vagal neurons in the nucleus ambiguus.
    Brain research, 2010, Aug-06, Volume: 1347

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Clonidine; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Heart; Medulla Oblongata; Neurons; Pyridazines; Rats; Synaptic Transmission; Vagus Nerve

2010
Encoding of the cough reflex in anesthetized guinea pigs.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 300, Issue:2

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Biphenyl Compounds; Citric Acid; Cough; Dose-Response Relationship, Drug; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Mechanoreceptors; Propionates; Quinoxalines; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Recurrent Laryngeal Nerve; Reflex; Respiratory Mucosa; Sensory Receptor Cells; Solitary Nucleus; Substance P; Trachea; Vagus Nerve; Valine

2011
Spatiotemporal organization and thalamic modulation of seizures in the mouse medial thalamic-anterior cingulate slice.
    Epilepsia, 2011, Volume: 52, Issue:12

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Biological Clocks; Calcium; Corpus Callosum; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes; Gyrus Cinguli; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscimol; Neural Pathways; Seizures; Thalamus

2011
Potent and direct presynaptic modulation of glycinergic transmission in rat spinal neurons by atrial natriuretic peptide.
    Brain research bulletin, 2013, Volume: 99

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cyclic GMP; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Inhibitory Postsynaptic Potentials; Lidocaine; Neurons; Peptides, Cyclic; Potassium Channel Blockers; Presynaptic Terminals; Rats; Rats, Wistar; Spinal Cord; Thionucleotides

2013
KCC2 function modulates in vitro ictogenesis.
    Neurobiology of disease, 2015, Volume: 79

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bumetanide; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Antagonists; K Cl- Cotransporters; Male; Rats, Sprague-Dawley; Sodium Potassium Chloride Symporter Inhibitors; Symporters; Thiazoles; Thiazolidines; Thioglycolates; Tissue Culture Techniques

2015
Chronaxie Measurements in Patterned Neuronal Cultures from Rat Hippocampus.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Axons; Bicuculline; Calcium; Chronaxy; Dendrites; Embryo, Mammalian; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; Potassium Channel Blockers; Primary Cell Culture; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate

2015
Hypersynchronous ictal onset in the perirhinal cortex results from dynamic weakening in inhibition.
    Neurobiology of disease, 2016, Volume: 87

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cations, Monovalent; Cerebral Cortex; Excitatory Amino Acid Antagonists; GABA Antagonists; Neurons; Periodicity; Phosphinic Acids; Picrotoxin; Piperazines; Potassium; Propanolamines; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Seizures; Tissue Culture Techniques

2016
Conveyance of cortical pacing for parkinsonian tremor-like hyperkinetic behavior by subthalamic dysrhythmia.
    Cell reports, 2021, 04-20, Volume: 35, Issue:3

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Globus Pallidus; Glutamic Acid; Humans; Hyperkinesis; Male; Membrane Potentials; Mice, Inbred C57BL; Motor Cortex; Muscle, Skeletal; Optogenetics; Parkinson Disease, Secondary; Rats; Rats, Wistar; Subthalamic Nucleus; Synapses; Synaptic Transmission; Tremor

2021