4-amino-5-hexynoic acid has been researched along with vigabatrin in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (86.96) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barth, J; Heydt, JG; Jung, MJ; Kolb, M | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Schechter, PJ; Tranier, Y | 1 |
| Jäckel, R; Löscher, W; Müller, F | 1 |
| Andersson, U; Häggström, JE | 1 |
| Donoso, AO | 1 |
| Blanchard, JS; Cubells, JF; Makman, MH | 1 |
| Larsson, OM; Schousboe, A; Seiler, N | 1 |
| Blanchard, JS; Cubells, JF; Makman, MH; Smith, DM | 1 |
| Banzan, AM; Donoso, AO; Muñoz, V | 1 |
| Bolkenius, FN; Seiler, N | 1 |
| Beart, PM; Lloyd, KG; Scatton, B | 1 |
| Sawynok, J | 1 |
| Hare, TA; Tamminga, CA; Thaker, GK | 1 |
| Löscher, W | 1 |
| Alken, RG; Haegele, KD; Huebert, ND; Schoun, J | 1 |
| Buckett, WR | 1 |
| Graham, LT; Jobe, PC; Mims, ME; Ray, TB | 1 |
| Abdul-Ghani, AS; Bradford, HF; Norris, PJ; Smith, CC | 1 |
| Böhlen, P; Huot, S; Mellet, M; Palfreyman, MG | 1 |
| Abdul-Ghani, AS; Bradford, HF; Coutinho-Netto, J | 1 |
| Contestabile, R; Grimm, B; Harwood, JL; John, RA; Tyacke, RJ | 1 |
| Hörstermann, D; Löscher, W | 1 |
1 review(s) available for 4-amino-5-hexynoic acid and vigabatrin
| Article | Year |
|---|---|
GABA system: clinical research and treatment of tardive dyskinesia.
Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Substantia Nigra; Valproic Acid; Vigabatrin | 1983 |
1 trial(s) available for 4-amino-5-hexynoic acid and vigabatrin
| Article | Year |
|---|---|
GABA system: clinical research and treatment of tardive dyskinesia.
Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Substantia Nigra; Valproic Acid; Vigabatrin | 1983 |
22 other study(ies) available for 4-amino-5-hexynoic acid and vigabatrin
| Article | Year |
|---|---|
Synthesis and evaluation of mono-, di-, and trifluoroethenyl-GABA derivatives as GABA-T inhibitors.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Hydrocarbons, Fluorinated; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Rabbits; Spectrophotometry, Infrared; Structure-Activity Relationship; Swine | 1987 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Effect of GABA-transminase inhibition on rectal temperature in mice.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Body Temperature; Brain Chemistry; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Rectum; Vigabatrin | 1977 |
Anticonvulsant and proconvulsant effects of inhibitors of GABA degradation in the amygdala-kindling model.
Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Amygdala; Animals; Anticonvulsants; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kindling, Neurologic; Male; Models, Biological; Rats; Rats, Inbred Strains; Vigabatrin | 1989 |
GABA agonists in cebus monkeys with neuroleptic-induced persistent dyskinesias.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Antipsychotic Agents; Cebus; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Isoxazoles; Male; Vigabatrin | 1988 |
Luteinizing hormone release induced by noradrenaline after administration of drugs that increase hypothalamic GABA levels.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Female; gamma-Aminobutyric Acid; Hypothalamus; Injections, Intraventricular; Luteinizing Hormone; Norepinephrine; Rats; Vigabatrin | 1988 |
The effects of in vivo inactivation of GABA-transaminase and glutamic acid decarboxylase on levels of GABA in the rat retina.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Cyclohexanecarboxylic Acids; Drug Combinations; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Rats; Retina; Time Factors; Vigabatrin | 1987 |
Stereoselective uptake of the GABA-transaminase inhibitors gamma-vinyl GABA and gamma-acetylenic GABA into neurons and astrocytes.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Animals, Newborn; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Kinetics; Mice; Mice, Inbred Strains; Neurons; Stereoisomerism; Structure-Activity Relationship; Vigabatrin | 1986 |
In vivo action of enzyme-activated irreversible inhibitors of glutamic acid decarboxylase and gamma-aminobutyric acid transaminase in retina vs. brain.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Analysis of Variance; Animals; Brain; Cyclohexanecarboxylic Acids; Glutamate Decarboxylase; Male; Organ Specificity; Rats; Rats, Inbred Strains; Retina; Vigabatrin | 1986 |
Inhibitory actions of GABA on luteinizing hormone secretion.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Brain; Estrus; Female; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Luteinizing Hormone; Male; Norepinephrine; Orchiectomy; Ovariectomy; Rats; Secretory Rate; Vigabatrin | 1986 |
Polyamine reutilization and turnover in brain.
Topics: Alkynes; Aminocaproates; Animals; Brain; Brain Chemistry; Eflornithine; Male; Mice; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine; Vigabatrin | 1985 |
Subchronic administration of GABAergic agonists elevates [3H]GABA binding and produces tolerance in striatal dopamine catabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Baclofen; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Isoxazoles; Male; Pyrones; Rats; Rats, Inbred Strains; Vigabatrin | 1985 |
GABAergic mechanisms in antinociception.
Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Analgesics; Animals; Baclofen; Bicuculline; Central Nervous System; gamma-Aminobutyric Acid; Isoxazoles; Mice; Muscimol; Pain; Rats; Stereoisomerism; Substance P; Synaptic Transmission; Vigabatrin | 1984 |
Cardiovascular effects of GABA, GABA-aminotransferase inhibitors and valproic acid following systemic administration in rats, cats and dogs: pharmacological approach to localize the site of action.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Binding Sites; Cats; Cyclohexanecarboxylic Acids; Dogs; Ethanolamines; Female; gamma-Aminobutyric Acid; Hemodynamics; Male; Rats; Rats, Inbred Strains; Species Specificity; Transaminases; Valproic Acid; Vigabatrin | 1982 |
Determination of the R(-)- and S(+)-enantiomers of gamma-vinyl-gamma-aminobutyric acid in human body fluids by gas chromatography--mass spectrometry.
Topics: Alkynes; Aminocaproates; Body Fluids; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Male; Stereoisomerism; Time Factors; Vigabatrin | 1983 |
Irreversible inhibitors of GABA transaminase induce antinociceptive effects and potentiate morphine.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Ataxia; Brain Chemistry; Drug Synergism; Female; gamma-Aminobutyric Acid; Humans; Male; Mice; Morphine; Morphine Dependence; Naloxone; Pain; Rats; Stereoisomerism; Transaminases; Vigabatrin | 1980 |
Effects of gamma-acetylenic GABA and gamma-vinyl GABA on electrically-induced spinal cord convulsions and on spinal cord GABA concentration.
Topics: Alkynes; Aminocaproates; Animals; Electroshock; Female; gamma-Aminobutyric Acid; Rats; Seizures; Spinal Cord; Structure-Activity Relationship; Time Factors; Vigabatrin | 1980 |
Effects of gamma-acetylenic GABA and gamma-vinyl GABA on synaptosomal release and uptake of GABA.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Cerebral Cortex; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Rats; Synaptosomes; Veratrine; Vigabatrin | 1981 |
The effect of gamma-vinyl GABA and gamma-acetylenic GABA on the concentration of homocarnosine in brain and CSF of the rat.
Topics: Alkynes; Aminocaproates; Animals; Brain; Carnosine; Chromatography, Ion Exchange; Dose-Response Relationship, Drug; Male; Rats; Vigabatrin | 1980 |
The action of gamma-vinyl-GABA and gamma-acetylenic-GABA on the resting and stimulated release of GABA in vivo.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Brachial Plexus; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glutamates; Motor Cortex; Rats; Somatosensory Cortex; Vigabatrin | 1980 |
Reactions of glutamate semialdehyde aminotransferase (glutamate-1-semialdehyde 2,1 aminomutase) with vinyl and acetylenic substrate analogues analysed by rapid scanning spectrophotometry.
Topics: Acetylene; Alkynes; Amino Acids, Diamino; Aminocaproates; gamma-Aminobutyric Acid; Intramolecular Transferases; Isomerases; Kinetics; Molecular Structure; Pisum sativum; Spectrum Analysis; Substrate Specificity; Vigabatrin | 1995 |
Differential effects of vigabatrin, gamma-acetylenic GABA, aminooxyacetic acid, and valproate on levels of various amino acids in rat brain regions and plasma.
Topics: Alkynes; Amino Acids; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Brain Chemistry; Female; gamma-Aminobutyric Acid; Rats; Rats, Wistar; Valproic Acid; Vigabatrin | 1994 |