4-amino-5-hexynoic acid and gamma-aminobutyric acid

4-amino-5-hexynoic acid has been researched along with gamma-aminobutyric acid in 60 studies

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-199050 (83.33)18.7374
1990's9 (15.00)18.2507
2000's1 (1.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Schechter, PJ; Tranier, Y1
De Luca, G; Di Giorgio, RM; Macaione, S; Nisticó, G1
Ackermann, RF; Engel, J; Myslobodsky, MS1
Agmo, A; Gutiérrez, M; Guzmán, M; Pruneda, R1
Blomqvist, A; Bull, MS1
Cremades, A; Del Rio-Garcia, J1
James, MD; Leigh, AJ; Wilson, CA1
Kuschinsky, K; Wenzel, J1
Agmo, A; Paredes, R; Soria, P1
Doger, E; Eguibar, JR; Holmgren, B; Urbá-Holmgren, R1
Jäckel, R; Löscher, W; Müller, F1
Andersson, U; Häggström, JE1
Kihara, M; Kubo, T; Misu, Y1
Agmo, A; Tarasco, C1
Agmo, A; Paredes, R1
Dickson, C; Sawynok, J2
Lindgren, S2
Löscher, W3
Donoso, AO1
Banzan, AM; Donoso, AO1
Andén, NE; Lindgren, S; Magnusson, A1
Blanchard, JS; Cubells, JF; Makman, MH1
Debeljuk, L; Torres Alemán, I1
Banzan, AM; Donoso, AO; Muñoz, V1
Cardinali, DP; Rosenstein, RE1
Bennett, JP; Cruz, CJ; Ferrari, MB1
Andén, NE; Lindgren, S2
Beart, PM; Lloyd, KG; Scatton, B1
Sawynok, J1
Casey, DE; Christensen, TR; Gerlach, J; Magelund, G1
Acs, Z; Erdö, SL; Fiók, J; Makara, GB1
Kennedy, B; Leonard, BE1
Breese, GR; Frye, GD1
Bjørndal, N; Casey, DE; Christensson, E; Gerlach, J1
Frey, HH; Löscher, W; Reiche, R; Schultz, D1
Hare, TA; Tamminga, CA; Thaker, GK1
Bond, A; Neal, H1
Cattabeni, F; Eli, M1
Debeljuk, L; Díaz, MD; Maines, VM; Seilicovich, A1
Buckett, WR1
Poshivalov, VP1
Graham, LT; Jobe, PC; Mims, ME; Ray, TB1
Abdul-Ghani, AS; Bradford, HF; Norris, PJ; Smith, CC1
Myslobodsky, MS; Valenstein, ES1
Donoso, AO; Zárate, MB1
De Luca, G; Di Giorgio, RM; Di Perri, R; Macaione, S; Nisticò, G1
Acs, Z; Fiók, J; Stark, E1
Abdul-Ghani, AS; Bradford, HF; Coutinho-Netto, J1
Enna, SJ; Ferkany, JW; Strong, R1
Butler, IJ; Enna, SJ; Ferkany, JW1
Contestabile, R; Grimm, B; Harwood, JL; John, RA; Tyacke, RJ1
Hörstermann, D; Löscher, W1
Agmo, A; Belzung, C; Giordano, M1
Fenske, C; Hole, DR; Kalia, V; Wilson, CA1

Reviews

1 review(s) available for 4-amino-5-hexynoic acid and gamma-aminobutyric acid

ArticleYear
GABA system: clinical research and treatment of tardive dyskinesia.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Substantia Nigra; Valproic Acid; Vigabatrin

1983

Trials

2 trial(s) available for 4-amino-5-hexynoic acid and gamma-aminobutyric acid

ArticleYear
gamma-Acetylenic GABA in tardive dyskinesia.
    Archives of general psychiatry, 1980, Volume: 37, Issue:12

    Topics: 4-Aminobutyrate Transaminase; Adult; Aged; Alkynes; Aminocaproates; Antipsychotic Agents; Brain; Dopamine; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Prolactin; Transaminases

1980
GABA system: clinical research and treatment of tardive dyskinesia.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Substantia Nigra; Valproic Acid; Vigabatrin

1983

Other Studies

58 other study(ies) available for 4-amino-5-hexynoic acid and gamma-aminobutyric acid

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Effect of GABA-transminase inhibition on rectal temperature in mice.
    Pharmacology, biochemistry, and behavior, 1977, Volume: 6, Issue:6

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Body Temperature; Brain Chemistry; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Rectum; Vigabatrin

1977
Effects of ethanolamine-O-sulphate and gamma-acetylenic-GABA on GABA content, GAD and GABA-T in various areas of chick brain after intraventricular microinjection.
    Journal of neurochemistry, 1979, Volume: 33, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Brain; Carboxy-Lyases; Chickens; Ethanolamines; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Organ Specificity; Transaminases

1979
Effects of gamma-acetylenic GABA and gamma-vinyl GABA on metrazol-activated, and kindled seizures.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:3

    Topics: Alkynes; Aminocaproates; Animals; Arousal; Drug Interactions; Electric Stimulation; Electroencephalography; gamma-Aminobutyric Acid; Male; Pentylenetetrazole; Rats; Seizures

1979
GABAergic drugs and conflict behavior in the rat: lack of similarities with the actions of benzodiazepines.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:3

    Topics: Alkynes; Aminocaproates; Animals; Baclofen; Behavior, Animal; Benzodiazepines; Bicuculline; Brain; Conflict, Psychological; Drug Interactions; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Nicotinic Acids; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission

1991
Immunocytochemical identification of GABA in astrocytes located in white matter after inhibition of GABA-transaminase with gamma-acetylenic GABA.
    Journal of neurocytology, 1991, Volume: 20, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Astrocytes; Brain Stem; Cerebral Cortex; gamma-Aminobutyric Acid; Immunoenzyme Techniques; Male; Microscopy, Immunoelectron; Organ Specificity; Rats; Rats, Inbred Strains

1991
GABAergic mechanisms in morphine-induced hypothermia.
    European journal of pharmacology, 1990, Oct-23, Volume: 187, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Baclofen; Body Temperature; Female; Flumazenil; gamma-Aminobutyric Acid; Male; Morphine; Rats; Rats, Inbred Strains

1990
Role of gamma-aminobutyric acid in the zona incerta in the control of luteinizing hormone release and ovulation.
    Neuroendocrinology, 1990, Volume: 52, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Baclofen; Diencephalon; Estradiol; Female; GABA Antagonists; gamma-Aminobutyric Acid; Luteinizing Hormone; Muscimol; Ovariectomy; Ovulation; Proestrus; Progesterone; Rats; Rats, Inbred Strains

1990
Effects of morphine on gamma-aminobutyric acid turnover in the basal ganglia. Possible correlation with its biphasic action on motility.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:7

    Topics: Alkynes; Aminocaproates; Animals; Brain Chemistry; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Morphine; Rats; Rats, Inbred Strains; Synaptic Transmission

1990
GABAergic drugs and lordosis behavior in the female rat.
    Hormones and behavior, 1989, Volume: 23, Issue:3

    Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Estradiol; Female; gamma-Aminobutyric Acid; Isoxazoles; Oxazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Behavior, Animal; Taurine

1989
GABAergic modulation of yawning behavior.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Acetylcholine; Alkynes; Aminocaproates; Animals; Convulsants; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Yawning

1989
Anticonvulsant and proconvulsant effects of inhibitors of GABA degradation in the amygdala-kindling model.
    European journal of pharmacology, 1989, Apr-12, Volume: 163, Issue:1

    Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Amygdala; Animals; Anticonvulsants; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kindling, Neurologic; Male; Models, Biological; Rats; Rats, Inbred Strains; Vigabatrin

1989
GABA agonists in cebus monkeys with neuroleptic-induced persistent dyskinesias.
    Psychopharmacology, 1988, Volume: 94, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Antipsychotic Agents; Cebus; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Isoxazoles; Male; Vigabatrin

1988
GABA transaminase inhibitors enhance the release of endogenous GABA but decrease the release of beta-alanine evoked by electrical stimulation of slices of the rat medulla oblongata.
    Life sciences, 1988, Volume: 42, Issue:19

    Topics: 4-Aminobutyrate Transaminase; Alanine; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; beta-Alanine; Cyclohexanecarboxylic Acids; Electric Stimulation; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Medulla Oblongata; Rats; Rats, Inbred Strains

1988
Interactions between naloxone and GABA in the control of locomotor activity in the rat.
    Journal of neural transmission, 1985, Volume: 61, Issue:3-4

    Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Brain; gamma-Aminobutyric Acid; Male; Motor Activity; Naloxone; Neural Inhibition; Rats; Rats, Inbred Strains; Synaptic Transmission

1985
GABAergic drugs and sexual behaviour in the male rat.
    European journal of pharmacology, 1985, Jun-19, Volume: 112, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Behavior, Animal

1985
D-Baclofen is an antagonist at baclofen receptors mediating antinociception in the spinal cord.
    Pharmacology, 1985, Volume: 31, Issue:5

    Topics: Alkynes; Aminobutyrates; Aminocaproates; Analgesics; Animals; Baclofen; Carbamazepine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Morphine; Norepinephrine; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Receptors, GABA-B; Spinal Cord

1985
Effects of GABAergic drugs on the GABA turnover in the substantia nigra and the corpus striatum of the rat.
    Journal of neural transmission, 1987, Volume: 69, Issue:1-2

    Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Corpus Striatum; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra

1987
Development of tolerance to the anticonvulsant effect of GABAmimetic drugs in genetically epilepsy-prone gerbils.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:4

    Topics: Acetates; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Diazepam; Drug Tolerance; Epilepsy; Female; gamma-Aminobutyric Acid; Gerbillinae; Isoxazoles; Male; Oxazoles; Valproic Acid

1986
Luteinizing hormone release induced by noradrenaline after administration of drugs that increase hypothalamic GABA levels.
    Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia, 1988, Volume: 38, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Female; gamma-Aminobutyric Acid; Hypothalamus; Injections, Intraventricular; Luteinizing Hormone; Norepinephrine; Rats; Vigabatrin

1988
Blockade of the LH surge and ovulation by GABA-T inhibitory drugs that increase brain GABA levels in rats.
    Psychoneuroendocrinology, 1986, Volume: 11, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Bicuculline; Brain Chemistry; Estrus; Female; gamma-Aminobutyric Acid; Gonadotropins, Equine; Luteinizing Hormone; Ovulation; Rats

1986
Regional differences in the changes in rat brain GABA concentrations post mortem and following inhibition of the synthesis and metabolism.
    Pharmacology & toxicology, 1987, Volume: 60, Issue:5

    Topics: Alkynes; Aminocaproates; Animals; Brain Chemistry; gamma-Aminobutyric Acid; Male; Postmortem Changes; Pyridoxine; Rats; Rats, Inbred Strains; Substantia Nigra

1987
The effects of in vivo inactivation of GABA-transaminase and glutamic acid decarboxylase on levels of GABA in the rat retina.
    Brain research, 1987, Sep-01, Volume: 419, Issue:1-2

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Cyclohexanecarboxylic Acids; Drug Combinations; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Rats; Retina; Time Factors; Vigabatrin

1987
gamma-Acetylenic GABA antagonizes the decrease in synaptosomal GABA concentrations but not the seizures induced by 3-mercaptopropionic acid in rats.
    Biochemical pharmacology, 1986, Sep-15, Volume: 35, Issue:18

    Topics: 3-Mercaptopropionic Acid; Alkynes; Aminocaproates; Animals; Female; gamma-Aminobutyric Acid; Rats; Rats, Inbred Strains; Seizures; Sulfhydryl Compounds; Synaptosomes; Tissue Distribution

1986
GABA-mimetic compounds block haloperidol-induced hyperprolactinemia in rats.
    Advances in biochemical psychopharmacology, 1986, Volume: 42

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Dopamine; Ethanolamines; gamma-Aminobutyric Acid; Haloperidol; Luteinizing Hormone; Male; Orchiectomy; Pituitary Gland, Anterior; Prolactin; Rats; Secretory Rate

1986
Inhibitory actions of GABA on luteinizing hormone secretion.
    Advances in biochemical psychopharmacology, 1986, Volume: 42

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Brain; Estrus; Female; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Luteinizing Hormone; Male; Norepinephrine; Orchiectomy; Ovariectomy; Rats; Secretory Rate; Vigabatrin

1986
Effects of KCl-induced depolarization on the GABA concentration in the corpus striatum and in the substantia nigra.
    Journal of neural transmission, 1986, Volume: 66, Issue:3-4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alkynes; Aminocaproates; Animals; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamine; Male; Potassium Chloride; Pyridoxine; Rats; Rats, Inbred Strains; Substantia Nigra

1986
Melatonin increases in vivo GABA accumulation in rat hypothalamus, cerebellum, cerebral cortex and pineal gland.
    Brain research, 1986, Nov-29, Volume: 398, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Brain; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; Hypothalamus; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains

1986
GABA-mimetic drugs enhance apomorphine-induced contralateral turning in rats with unilateral nigrostriatal dopamine denervation: implications for the therapy of Parkinson's disease.
    Annals of neurology, 1987, Volume: 21, Issue:1

    Topics: Alkynes; Aminocaproates; Animals; Antiparkinson Agents; Apomorphine; Drug Synergism; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Nicotinic Acids; Parkinson Disease; Rats; Rats, Inbred Strains

1987
Effect of the normal nerve impulse flow on the synthesis and utilization of GABA in the rat substantia nigra.
    Journal of neural transmission, 1985, Volume: 61, Issue:1-2

    Topics: Alkynes; Amino Acids; Aminocaproates; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; gamma-Aminobutyric Acid; Isoniazid; Male; Neural Pathways; Pyridoxine; Rats; Rats, Inbred Strains; Substantia Nigra

1985
Subchronic administration of GABAergic agonists elevates [3H]GABA binding and produces tolerance in striatal dopamine catabolism.
    Brain research, 1985, May-27, Volume: 335, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Baclofen; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Isoxazoles; Male; Pyrones; Rats; Rats, Inbred Strains; Vigabatrin

1985
GABAergic mechanisms in antinociception.
    Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:4-6

    Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Analgesics; Animals; Baclofen; Bicuculline; Central Nervous System; gamma-Aminobutyric Acid; Isoxazoles; Mice; Muscimol; Pain; Rats; Stereoisomerism; Substance P; Synaptic Transmission; Vigabatrin

1984
On the use of enzyme inhibitors to study the synthesis and utilization of brain GABA.
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoniazid; Male; Pyridoxine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A

1984
Site of gamma-aminobutyric acid (GABA)-mediated inhibition of growth hormone secretion in the rat.
    Neuroendocrinology, 1984, Volume: 39, Issue:6

    Topics: Afferent Pathways; Alkynes; Aminocaproates; Animals; Bicuculline; gamma-Aminobutyric Acid; Growth Hormone; Hypothalamus, Middle; Male; Median Eminence; Muscimol; Nerve Fibers; Rats; Rats, Inbred Strains; Receptors, GABA-A; Somatostatin

1984
Similarity between the action of nicotinamide and diazepam on neurotransmitter metabolism in the rat [proceedings].
    Biochemical Society transactions, 1980, Volume: 8, Issue:1

    Topics: Alkynes; Aminocaproates; Amygdala; Animals; Brain; Diazepam; gamma-Aminobutyric Acid; Hippocampus; Hydroxyindoleacetic Acid; Male; Niacinamide; Organ Specificity; Rats; Serotonin; Tryptophan

1980
GABAergic modulation of ethanol-induced motor impairment.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminobutyrates; Aminocaproates; Animals; Bicuculline; Brain; Ethanol; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Skills; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A

1982
Effect of apomorphine and gabaergic drugs in monkeys pretreated with haloperidol.
    Psychopharmacology, 1983, Volume: 79, Issue:2-3

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Apomorphine; Chlorocebus aethiops; Female; gamma-Aminobutyric Acid; Haloperidol; Hemodynamics; Isoxazoles; Male; Motor Activity; Muscimol; Picrotoxin

1983
High anticonvulsant potency of gamma-aminobutyric acid (GABA)mimetic drugs in gerbils with genetically determined epilepsy.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:3

    Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Gerbillinae; Isoxazoles; Male; Mice; Seizures; Valproic Acid

1983
The influence of GABAergic drugs on PGO activity in the cat.
    Neuropharmacology, 1983, Volume: 22, Issue:7

    Topics: Alkynes; Aminocaproates; Animals; Brain; Cats; Chlordiazepoxide; Electroencephalography; Female; gamma-Aminobutyric Acid; Geniculate Bodies; Isoxazoles; Male; Muscimol; Occipital Lobe; Pons

1983
Involvement of GABA in the antinociceptive effect of gamma-acetylenic GABA (GAG), an inhibitor of GABA-transaminase.
    General pharmacology, 1983, Volume: 14, Issue:6

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Analgesics; Animals; Baclofen; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Theophylline; Time Factors

1983
Cardiovascular effects of GABA, GABA-aminotransferase inhibitors and valproic acid following systemic administration in rats, cats and dogs: pharmacological approach to localize the site of action.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 257, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Binding Sites; Cats; Cyclohexanecarboxylic Acids; Dogs; Ethanolamines; Female; gamma-Aminobutyric Acid; Hemodynamics; Male; Rats; Rats, Inbred Strains; Species Specificity; Transaminases; Valproic Acid; Vigabatrin

1982
Endogenous gamma-hydroxybutyrate in rat brain areas: postmortem changes and effects of drugs interfering with gamma-aminobutyric acid metabolism.
    Journal of neurochemistry, 1983, Volume: 41, Issue:2

    Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Brain; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Hydroxybutyrates; Isoniazid; Kinetics; Male; Postmortem Changes; Rats; Rats, Inbred Strains; Sodium Oxybate; Tissue Distribution

1983
Prolonged treatment with gamma-aminobutyric acid (GABA)-mimetic substances in prepubertal male rats.
    Archives of andrology, 1983, Volume: 10, Issue:3

    Topics: 4-Butyrolactone; Alkynes; Aminocaproates; Animals; Body Weight; gamma-Aminobutyric Acid; Male; Organ Size; Prolactin; Rats; Rats, Inbred Strains; Seminal Vesicles; Sexual Maturation; Testis; Time Factors

1983
Irreversible inhibitors of GABA transaminase induce antinociceptive effects and potentiate morphine.
    Neuropharmacology, 1980, Volume: 19, Issue:8

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Ataxia; Brain Chemistry; Drug Synergism; Female; gamma-Aminobutyric Acid; Humans; Male; Mice; Morphine; Morphine Dependence; Naloxone; Pain; Rats; Stereoisomerism; Transaminases; Vigabatrin

1980
[GABA-ergic correlates of aggression and intraspecies sociability of mice subjected to isolation].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 91, Issue:5

    Topics: Aggression; Alkynes; Aminocaproates; Animals; Bicuculline; gamma-Aminobutyric Acid; Humans; Male; Mice; Mice, Inbred Strains; Muscimol; Picrotoxin; Semicarbazides; Social Behavior; Social Isolation

1981
Effects of gamma-acetylenic GABA and gamma-vinyl GABA on electrically-induced spinal cord convulsions and on spinal cord GABA concentration.
    Life sciences, 1980, Nov-24, Volume: 27, Issue:21

    Topics: Alkynes; Aminocaproates; Animals; Electroshock; Female; gamma-Aminobutyric Acid; Rats; Seizures; Spinal Cord; Structure-Activity Relationship; Time Factors; Vigabatrin

1980
Effects of gamma-acetylenic GABA and gamma-vinyl GABA on synaptosomal release and uptake of GABA.
    Biochemical pharmacology, 1981, Jun-01, Volume: 30, Issue:11

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Cerebral Cortex; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Rats; Synaptosomes; Veratrine; Vigabatrin

1981
An inability of gamma-acetylenic GABA to block eating evoked by hypothalamic stimulation.
    Behavioural brain research, 1980, Volume: 1, Issue:4

    Topics: Alkynes; Aminocaproates; Animals; Body Weight; Brain Chemistry; Electric Stimulation; Feeding Behavior; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamus, Middle; Male; Rats; Rats, Inbred Strains

1980
Changes in prolactin release caused by GABA and endogenous GABA increase in rats.
    Brain research bulletin, 1981, Volume: 7, Issue:4

    Topics: Alkynes; Aminocaproates; Animals; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Histamine; Kinetics; Male; Prolactin; Rats

1981
Effects of intraventricular gamma-acetylenic-GABA on GABA concentrations, GABA-T and GAD in several areas of the chick brain.
    Monographs in neural sciences, 1980, Volume: 5

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Behavior, Animal; Brain Chemistry; Carboxy-Lyases; Chickens; Electroencephalography; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections, Intraventricular; Transaminases

1980
Possible inhibitory influence of gamma-aminobutyric acid on growth hormone secretion in the rat.
    The Journal of endocrinology, 1981, Volume: 91, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Depression, Chemical; Ethanolamines; gamma-Aminobutyric Acid; Growth Hormone; In Vitro Techniques; Male; Pituitary Gland; Rats

1981
The action of gamma-vinyl-GABA and gamma-acetylenic-GABA on the resting and stimulated release of GABA in vivo.
    Brain research, 1980, Jun-09, Volume: 191, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Brachial Plexus; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glutamates; Motor Cortex; Rats; Somatosensory Cortex; Vigabatrin

1980
Dopamine receptor supersensitivity in the corpus striatum following chronic elevation of brain gamma-aminobutyric acid.
    Journal of neurochemistry, 1980, Volume: 34, Issue:1

    Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Brain; Corpus Striatum; gamma-Aminobutyric Acid; Isoniazid; Kinetics; Male; Muscimol; Organ Specificity; Rats; Receptors, Dopamine

1980
Chronology of neurochemical alterations induced by GABA agonist administration.
    Advances in biochemical psychopharmacology, 1981, Volume: 26

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Brain Chemistry; Choline; Corpus Striatum; gamma-Aminobutyric Acid; Kinetics; Male; Rats; Receptors, Dopamine

1981
Reactions of glutamate semialdehyde aminotransferase (glutamate-1-semialdehyde 2,1 aminomutase) with vinyl and acetylenic substrate analogues analysed by rapid scanning spectrophotometry.
    The Biochemical journal, 1995, Jul-01, Volume: 309 ( Pt 1)

    Topics: Acetylene; Alkynes; Amino Acids, Diamino; Aminocaproates; gamma-Aminobutyric Acid; Intramolecular Transferases; Isomerases; Kinetics; Molecular Structure; Pisum sativum; Spectrum Analysis; Substrate Specificity; Vigabatrin

1995
Differential effects of vigabatrin, gamma-acetylenic GABA, aminooxyacetic acid, and valproate on levels of various amino acids in rat brain regions and plasma.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 349, Issue:3

    Topics: Alkynes; Amino Acids; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Brain Chemistry; Female; gamma-Aminobutyric Acid; Rats; Rats, Wistar; Valproic Acid; Vigabatrin

1994
Interactions between dopamine and GABA in the control of ambulatory activity.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:8-9

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; GABA Agents; gamma-Aminobutyric Acid; Male; Motor Activity; Rats; Rats, Wistar; Valproic Acid

1996
Effect of gonadal steroids and gamma-aminobutyric acid on LH release and dopamine expression and activity in the zona incerta in rats.
    Journal of reproduction and fertility, 1999, Volume: 117, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Aminobutyrate Transaminase; Actins; Alkynes; Aminocaproates; Analysis of Variance; Animals; Brain; Dopamine; Enzyme Inhibitors; Estradiol; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamus; Luteinizing Hormone; Progesterone; Rats; Rats, Wistar; RNA, Messenger; Tyrosine 3-Monooxygenase

1999