4-amino-3-phenylbutyric acid has been researched along with gamma-aminobutyric acid in 124 studies
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 27 (21.77) | 18.7374 |
1990's | 12 (9.68) | 18.2507 |
2000's | 17 (13.71) | 29.6817 |
2010's | 51 (41.13) | 24.3611 |
2020's | 17 (13.71) | 2.80 |
Authors | Studies |
---|---|
Sizov, PI | 1 |
Chesnokova, IaM; Filimonov, VG; Sheveleva, GA; Sizov, PI | 1 |
Iasnetsov, VS; Sizov, PI | 2 |
Bul'on, VV; Khnychenko, LK; Zavodskaia, IS | 1 |
Adojaan, A; Allikmets, L; Harro, J; Kiivet, RA; Rägo, L | 1 |
Johnston, GA; Kerr, DI; Ong, J; Prager, RH | 1 |
Abramets, II; Samoĭlovich, IM | 1 |
Khaunina, RA; Lapin, IP | 1 |
Borsheva, AA; Kuzam, LN; Volkov, AE | 1 |
Iasnetsov, VS; Novikov, VE | 1 |
Abramets, II; Komissarov, IV | 2 |
Allikmets, LH; Harro, JE; Kiivet, RA; Rägo, LK | 1 |
Zharkovskaia, TA; Zharkovskiĭ, AM | 1 |
Abramets, II; Komissarov, IV; Samoĭlovich, IM | 1 |
Gorokhov, EA; Mokrousova, TN; Selivanova, IG; Skoromets, AA; Uriupova, GN | 1 |
Karlov, VA; Megdiatov, RS | 1 |
Johnston, AR; Kerr, DI; Ong, J | 1 |
Skibitskiĭ, VV | 2 |
Bogachev, NA; Kovalev, GV; Ostrovskiĭ, OV; Petrianik, VD; Spasov, AA | 1 |
Danilin, VP; Krylov, EN; Magalif, AIu; Rait, ML | 1 |
Gol'dblat, IuV; Lapin, IP | 1 |
Allikmets, LKh; Riago, LK; Sarv, KhA | 1 |
Allikmets, LKh; Nurk, AM; Riago, LK | 1 |
Allikmets, LKh; Korneev, AIa; Nurk, AM; Riago, LK | 1 |
Ostrovskaia, RU; Trofimov, SS | 1 |
Kresiun, VI | 1 |
Kovalev, GI; Prikhozhan, AV; Raevskiĭ, KS | 1 |
Erofeev, NP; Ivanova, NA; Kovalev, GV; Orlov, RS; Shebeko, LV | 1 |
Dukhanin, AS; Filimonov, VG; Sergeev, PV; Sheveleva, GA; Sizov, PI | 1 |
Allen, RD; Doolette, DJ; Duke, RK; Johnston, GA; Kerr, DI; Mewett, KN; Ong, J | 1 |
Safonov, VA; Tarakanov, IA | 1 |
Tarakanov, IA | 2 |
Antipova, AIu; Klauchek, SV; Makarov, VI; Nalivaĭko, IO; Tiurenkov, IN | 1 |
Safonov, VA; Tarakanov, IA; Tikhomirova, LN | 1 |
Goncharenko, NV; Pankrat'ev, DV; Talalaenko, AN | 2 |
Lapin, I | 1 |
KHAUNINA, RA | 1 |
Scholz, PM; Weiss, HR; Yan, L; Zhang, Q | 1 |
Shul'gina, GI; Ziablitseva, EA | 2 |
Begasheva, OI; Kabanova, SA; Komarova, IB; Nazarova, EK; Zykov, VP | 1 |
Goncharenko, NV; Krivobok, GK; Pankrat'ev, DV; Talalaenko, AN | 1 |
Dib, H; Lebedeva, SA; Ostrovskii, OV; Perfilova, VN; Popova, TA; Verovskii, VE | 1 |
Berestovitskaya, VM; Lebedeva, SA; Perfilova, VN; Tyurenkov, IN; Vasil'eva, OS; Volotova, EV | 1 |
Lebedeva, SA; Perfilova, VN; Tiurenkov, IN | 1 |
Cirule, H; Dambrova, M; Kalvinsh, I; Liepinsh, E; Veinberg, G; Zharkova, O; Zvejniece, L | 1 |
Pavlova, IV; Zyablitseva, EA | 1 |
Dambrova, M; Grinberga, S; Liepinsh, E; Pugovics, O; Zvejniece, L | 1 |
Kositsyn, NS; Shul'gina, GI; Zyablitseva, EA | 1 |
Pavlova, IV; Ziablintseva, EA | 1 |
Samotrueva, MA; Tyurenkov, IN | 1 |
Luzhnova, SA; Samotrueva, MA; Teplyĭ, DL; Tiurenkov, IN | 1 |
Khlebtsova, EV; Kuleshevskaia, NR; Samotrueva, MA; Teplyĭ, DL; Tiurenkov, IN | 1 |
Khan, AY; Magsalin, RM | 1 |
Isupov, IB; Likhodeeva, VA; Mandrikov, VB; Spasov, AA | 1 |
Berestovitskaia, VM; Kuleshevskaia, NR; Samotrueva, MA; Tiurenkov, IN; Vasil'eva, OS | 1 |
Bagmetova, VV; Berestovitskaia, VM; Krivitskaia, AN; Tiurenkov, IN; Vasil'eva, OS | 1 |
Belolipetskaia, VG; Blagodatskikh, SV; Merkulova, EV; Zhezlova, AV | 1 |
Khlebtsova, EB; Magomedov, MM; Samotrueva, MA; Tiurenkov, IN | 1 |
Borodin, DD; Ivanova, LB; Karamysheva, VI; Perfilova, VN | 1 |
Kurkin, DV; Litvinov, AA; Tarasov, AS; Tiurenkov, IN; Volotova, EV | 1 |
Bagmetova, VV; Berestovitskaia, VM; Borodkina, LE; Tiurenkov, IN; Vasil'eva, OS | 1 |
Balchand, K; Paton-Gay, CL; Rehm, J; Samokhvalov, AV | 1 |
Lebedeva, SA; Perfilova, VN; Riabukha, AF; Smirnova, LA; Suchkov, EA; Tiurenkov, IN | 1 |
Berestovitskaia, VM; Kurkin, DV; Mazina, NV; Vasil'eva, OS; Volotova, EV | 1 |
Gulyaeva, OV; Ivanova, LB; Perfilova, VN; Popova, TA; Prokofiev, II; Stepa, LI; Tyurenkov, IN | 1 |
Lebedeva, SA; Perfilova, VN; Ryabukha, AF; Smirnova, LA; Suchkov, EA; Tyurenkov, IN | 1 |
Cantrell, FL; Hwang, JQ; O'Connell, CW; Schneir, AB | 1 |
Kuznetsov, KA; Lova, VN; Reznikova, LB; Ryabukha, AF; Smirnova, LA; Suchkov, EA; Tyurenkov, IN | 1 |
Berestovitskaia, VM; Perfilova, VN; Sadikova, NV; Vasil'eva, OS | 1 |
Suvorinova, NIu; Zavadenko, NN | 1 |
Berestovitskaya, VM; Karamysheva, VI; Mikhailova, LI; Mokrousov, IS; Perfilova, VN; Reznikova, LB; Tyurenkov, IN; Vasil'eva, OS | 1 |
Aitbekov, KA; Bondarchuk, YI; Chutko, LS; Nikishena, IS; Surushkina, SY | 1 |
Karamysheva, VI; Lebedeva, SA; Mikhaĭlova, LI; Perfilova, VN; Popova, TA; Tiurenkov, IN; Zhakupova, GA | 1 |
Anisimova, TI; Bondarchuk, IL; Chutko, LS; Iakovenko, EA; Nikishena, IS; Sergeev, AV; Surushkina, SI | 1 |
Gou, Q; Liu, ZC; Qin, J; Zhang, ZF | 1 |
Anisimova, TI; Bondarchuk, IuL; Chutko, LS; Iakovenko, EA; Nikishena, IS; Surushkina, SIu | 1 |
Kobayashi, S; Oyamada, H; Tsubogo, T | 1 |
Bagmetova, VV; Krivitskaya, AN; Tyurenkov, IN | 1 |
Andres, D; Caldicott, D; Easton, C; Greene, SL; Little, M; Wong, A | 1 |
Berling, IL; Downes, MA; Grice, J; Isbister, GK; Mostafa, A; Roberts, MS | 1 |
Bardakov, SN; Ponomarev, VV; Samartsev, IN; Zhivolupov, SA | 1 |
Dambrova, M; Kalvinsh, I; Liepins, V; Rizhanova, K; Svalbe, B; Vavers, E; Veinberg, G; Zvejniece, L | 1 |
Archer, JR; Dargan, PI; Owen, DR; Wood, DM | 1 |
Belozertseva, I; Danysz, W; Franke, L; Nagel, J; Valastro, B | 1 |
Bagmetova, VV; Berestovitskaya, VM; Borodkina, LE; Tyurenkov, IN; Vasil'eva, OS | 1 |
Maximova, MY; Suanova, ET | 1 |
Perfilova, VN; Prokofiev, II; Sadikova, NV; Tyurenkov, IN | 1 |
Esin, OR; Esin, RG; Khairullin, IK; Tokareva, NV | 1 |
Duma, SN; Shcherbakova, LV | 1 |
Anisimova, TI; Chutko, LS; Surushkina, SY | 1 |
Khozhai, LI; Otellin, VA; Tyurenkov, IN | 1 |
Canino, P; Jackson, J; Sankary, S | 1 |
Borisov, AV; Kustova, MV; Ostrovskij, ОV; Perfilova, VN; Popova, TA; Prokofiev, II; Tyurenkov, IN; Zaypullaev, GI | 1 |
Friend, SF; Jimenez, B; Joshi, YB; Steiger, LR | 1 |
Mokrousov, IS; Ostrovskii, OV; Perfilova, VN; Popova, TA; Prokofiev, II; Tyurenkov, IN | 1 |
Borisov, AV; Mokrousov, IS; Perfilova, VN; Prokofiev, II; Tyurenkov, IN | 1 |
Bakulin, DA; Filina, IS; Kurkin, DV; Tyurenkov, IN; Volotova, EV | 1 |
Hardman, MI; Sprung, J; Weingarten, TN | 1 |
Jouney, EA | 1 |
Mokrousov, IS; Perfilova, VN; Popova, TA; Prokofiev, II; Tyurenkov, IN; Vasil'eva, OS; Vodopyanova, EG | 1 |
Arens, AM; Bangh, SA; Cole, JB; McCabe, DJ | 1 |
Isbister, GK; Isoardi, KZ; Kulawickrama, S | 1 |
Evenepoel, J; Titeca, K | 1 |
Matvienko, LS; Muzyko, EA; Naumenko, LV; Perfilova, VN; Tkacheva, GA; Tyurenkov, IN; Vasil'eva, OS | 1 |
Dambrova, M; Kupats, E; Stelfa, G; Vavers, E; Vrublevska, J; Zvejniece, B; Zvejniece, L | 1 |
Irie, T; Kikura-Hanajiri, R; Yamazaki, D | 1 |
Hosanagar, A; Tamarelli, C | 1 |
Leo, RJ; Mash, JE | 1 |
Dilley, J; Graves, JM; Kubsad, S; Liebelt, E | 1 |
Nagireddy, R; Ravishankar, DA; Sethi, R | 1 |
Doyno, CR; White, CM | 1 |
Cohen, PA; Ellison, RR; Gaufberg, SV; Gerona, R; Travis, JC | 1 |
Holland, A; Murray, A; VanDreese, B | 1 |
Balasanova, AA; Johnson, BE; McDermott, S | 1 |
Dominguez, MG; Manzar, S; Pena, F | 1 |
Anand, A; Wainblat, E; Weleff, J | 1 |
Monov, D; Pashanova, O | 1 |
Gerona, R; Hendrickson, RG; Moss, MJ; Rianprakaisang, TN | 1 |
6 review(s) available for 4-amino-3-phenylbutyric acid and gamma-aminobutyric acid
Article | Year |
---|---|
[Use of fenibut in psychiatry and neurology and its place among other psychotropic drugs (review of the literature)].
Topics: Adult; Child; Drug Evaluation; gamma-Aminobutyric Acid; Humans; Mental Disorders; Nervous System Diseases | 1989 |
Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug.
Topics: Animals; Anticonvulsants; Baclofen; Brain; Diazepam; Dopamine Agonists; Dyskinesias; Emotions; GABA Agonists; gamma-Aminobutyric Acid; Humans; Mental Disorders; Nootropic Agents; Phenethylamines; Piracetam; Stereoisomerism; Structure-Activity Relationship; Tranquilizing Agents | 2001 |
[Anxiety and fear in children and adolescents].
Topics: Adolescent; Child; Fear; Female; gamma-Aminobutyric Acid; Humans; Male; Phobic Disorders; Tranquilizing Agents | 2016 |
Acute phenibut withdrawal: A comprehensive literature review and illustrative case report.
Topics: Akathisia, Drug-Induced; Baclofen; Cyproheptadine; Dexmedetomidine; Diphenhydramine; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Haloperidol; Humans; Lorazepam; Male; Melatonin; Neuroleptic Malignant Syndrome; Olanzapine; Receptors, GABA; Substance Withdrawal Syndrome; Substance-Related Disorders; Young Adult | 2019 |
Phenibut (β-Phenyl-γ-Aminobutyric Acid): an Easily Obtainable "Dietary Supplement" With Propensities for Physical Dependence and Addiction.
Topics: Behavior, Addictive; Dietary Supplements; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Nootropic Agents; Substance-Related Disorders | 2019 |
Safety and Tolerability of the Anxiolytic and Nootropic Drug Phenibut: A Systematic Review of Clinical Trials and Case Reports.
Topics: Anti-Anxiety Agents; gamma-Aminobutyric Acid; Humans; Nootropic Agents; Substance-Related Disorders | 2020 |
6 trial(s) available for 4-amino-3-phenylbutyric acid and gamma-aminobutyric acid
Article | Year |
---|---|
[Experimental bases of the use of pharmacologic agents aimed at higher heat resistance of humans as means of individual protection].
Topics: Adjuvants, Immunologic; Anti-Anxiety Agents; Benzimidazoles; Body Temperature Regulation; gamma-Aminobutyric Acid; Hot Temperature; Humans; Microclimate; Occupational Health; Propranolol; Tranquilizing Agents | 1997 |
[Bioequivalence of anvifen and phenibut].
Topics: Area Under Curve; Capsules; Chromatography, High Pressure Liquid; Female; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Nootropic Agents; Reference Standards; Russia; Sleep Wake Disorders; Tablets; Therapeutic Equivalency; Young Adult | 2011 |
[The results of the pharmacological treatment of attention deficit hyperactivity disorder: evaluation with neuropsychological methods].
Topics: Attention; Attention Deficit Disorder with Hyperactivity; Child; Cognition; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Memory; Neuropsychological Tests | 2014 |
[Comorbidity of tics and stuttering].
Topics: Adolescent; Anticonvulsants; Child; Comorbidity; Female; gamma-Aminobutyric Acid; Humans; Male; Stuttering; Tics | 2014 |
[Asthenic disorders in children and their differentiated treatment].
Topics: Adolescent; Anti-Anxiety Agents; Anxiety; Asthenia; Biureas; Fatigue; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Neurasthenia; Psychiatric Status Rating Scales; Self-Assessment; Surveys and Questionnaires; Treatment Outcome | 2014 |
[Diagnosis and treatment of psychogenic dizziness in patients with arterial hypertension].
Topics: Aged; Anxiety; Asthenia; Betahistine; Dizziness; Female; gamma-Aminobutyric Acid; Humans; Hypertension; Male; Treatment Outcome | 2016 |
112 other study(ies) available for 4-amino-3-phenylbutyric acid and gamma-aminobutyric acid
Article | Year |
---|---|
[Action of GABA-positive preparations on uterus-stimulating effects of activating neuromediators, prostaglandin F2 alpha and oxytocin].
Topics: Animals; Anticonvulsants; Diazepam; Dinoprost; Electromyography; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Oxytocin; Rabbits; Rats; Uterine Contraction | 1992 |
[Experimental study of the effects of fenibut and seduxen on fetal development in the last third of pregnancy].
Topics: Abortion, Threatened; Animals; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; gamma-Aminobutyric Acid; Gestational Age; Pregnancy; Rats; Tranquilizing Agents | 1991 |
[The participation of the GABA-A and GABA-B receptors in the mechanism of the inhibition of the contractile activity in the rabbit myometrium under the influence of GABA, AOAA and fenibut].
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin; Rabbits; Receptors, GABA-A; Uterine Contraction | 1990 |
[The effect of GABA-ergic agents on the development of a neurogenic stomach lesion in rats].
Topics: Animals; Drug Evaluation, Preclinical; Electric Stimulation; gamma-Aminobutyric Acid; Lipid Peroxidation; Male; Piracetam; Rats; Receptors, GABA-A; Stomach Diseases; Tranquilizing Agents | 1990 |
Stress-protection action of beta-phenyl(GABA): involvement of central and peripheral type benzodiazepine binding sites.
Topics: Animals; Behavior, Animal; Benzodiazepinones; Blood Proteins; Carbolines; Drug Combinations; Female; Flunitrazepam; gamma-Aminobutyric Acid; Male; Premedication; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Time Factors | 1990 |
GABAB-receptor-mediated actions of baclofen in rat isolated neocortical slice preparations: antagonism by phosphono-analogues of GABA.
Topics: Animals; Baclofen; Cerebral Cortex; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Propylamines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
[Analysis of the nature of responses of neurons of rat spinal ganglia evoked by the activation of GABA-B receptors].
Topics: Animals; Cell Membrane Permeability; gamma-Aminobutyric Acid; Ganglia, Spinal; Ganglionic Stimulants; In Vitro Techniques; Neurons; Rats; Receptors, GABA-A; Stimulation, Chemical | 1989 |
[Effect of fenibut on the fetus and newborn infant after the treatment of gestoses].
Topics: Apgar Score; Female; Fetal Monitoring; Fetus; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy | 1989 |
[The GABA-ergic system and brain edema].
Topics: Animals; Anti-Anxiety Agents; Benactyzine; Benzodiazepines; Benzodiazepinones; Brain Edema; Brain Injuries; Diazepam; Drug Evaluation, Preclinical; Drug Interactions; Female; gamma-Aminobutyric Acid; Male; Nicotine; Parasympatholytics; Phentolamine; Picrotoxin; Rats; Receptors, GABA-A | 1985 |
[Effect of fenibut on the GABA B receptors of the spinal motor neurons].
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Motor Neurons; Neurotransmitter Agents; Rats; Receptors, GABA-A; Receptors, Neurotransmitter; Spinal Nerve Roots | 1985 |
[Ionic mechanisms of the effects of phenibut and GABA unrelated to changes in the function of chloride channels].
Topics: Animals; Anterior Horn Cells; Chlorides; Cyclic AMP; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Motor Neurons; Picrotoxin; Potassium; Rats; Receptors, GABA-A; Reflex; Sodium; Theophylline | 1985 |
[Effect of gamma-aminobutyric acid, its agonists and antagonists on uterine smooth muscle].
Topics: Animals; Bicuculline; Convulsants; Diazepam; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, GABA-A; Uterus | 1985 |
Benzodiazepine binding sites in mice forebrain and kidneys: evidence for similar regulation by GABA agonists.
Topics: Animals; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Kidney; Male; Mice; Muscimol; Receptors, GABA-A | 1986 |
[Antiabstinent action of fenibut and baclofen on a model of abstinence induced by the benzodiazepine receptor antagonist CGS 8216 in rats receiving diazepam].
Topics: Animals; Baclofen; Behavior, Animal; Diazepam; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Isoxazoles; Male; Pyrazoles; Rats; Receptors, GABA-A; Substance Withdrawal Syndrome; Tranquilizing Agents | 1987 |
[Harmanes allosterically modulate serotonin receptors of IA type].
Topics: Alkaloids; Allosteric Regulation; Animals; gamma-Aminobutyric Acid; Ganglia, Spinal; Harmine; In Vitro Techniques; Membrane Potentials; Neurons; Rats; Receptors, Serotonin; Serotonin | 1988 |
[Fenibut treatment of a vascular lesion of the vestibular analyzer].
Topics: Adult; Aged; Drug Evaluation; Female; gamma-Aminobutyric Acid; Humans; Labyrinth Diseases; Male; Middle Aged; Time Factors; Vertigo; Vestibule, Labyrinth | 1988 |
[Pathogenetic therapy of trigeminal neuralgia].
Topics: Adult; Aged; gamma-Aminobutyric Acid; Humans; Middle Aged; Pantothenic Acid; Personality; Tranquilizing Agents; Trigeminal Neuralgia | 1988 |
Differing actions of beta-phenyl-GABA and baclofen in the guinea pig isolated ileum.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; Male; Muscle Contraction | 1987 |
[Differential psychopharmacotherapy of heart rhythm disorders].
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzodiazepines; Drug Evaluation; Electrocardiography; gamma-Aminobutyric Acid; Hemodynamics; Humans; Middle Aged; MMPI; Oxazines; Psychotropic Drugs; Sulpiride | 1987 |
[Role of the GABAergic system in the mechanism of the stress-regulating action of phenibut].
Topics: Animals; gamma-Aminobutyric Acid; Hypothalamus; Male; Rats; Stress, Physiological; Thalamus; Tranquilizing Agents | 1987 |
[Effect of fenibut on the nocturnal sleep of patients with the alcoholic abstinence syndrome].
Topics: Adult; Electrodiagnosis; Ethanol; gamma-Aminobutyric Acid; Humans; Middle Aged; Sleep Stages; Sleep Wake Disorders; Substance Withdrawal Syndrome; Tranquilizing Agents | 1986 |
[Phenibut potentiation of the therapeutic action of antiparkinson agents].
Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Drug Therapy, Combination; Follow-Up Studies; gamma-Aminobutyric Acid; Humans; Middle Aged; Muscle Rigidity | 1986 |
[Effect of multiple daily administration of fenibut and diazepam on GABA and benzodiazepine receptors in the mouse brain].
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Brain; Diazepam; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Mice; Receptors, Drug; Receptors, Neurotransmitter | 1983 |
[Effect of the GABA receptor blockader bicuculline on the action of fenibut and diazepam].
Topics: Animals; Behavior, Animal; Bicuculline; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
[Fenibut binding with bicuculline-insensitive GABA receptors in the rat brain].
Topics: Animals; Bicuculline; Calcium; Corpus Striatum; Drug Resistance; gamma-Aminobutyric Acid; In Vitro Techniques; Isomerism; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Sodium | 1982 |
[Nootropic properties of gamma-aminobutyric acid derivatives].
Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; Baclofen; Butyrates; Conditioning, Classical; gamma-Aminobutyric Acid; Humans; Hydroxybutyrates; Hypoxia; Lithium; Mice; Organometallic Compounds; Piracetam; Sodium Oxybate | 1984 |
[Effect of phenibut and eglonyl on frequency of tachyarrhythmia paroxysms and central hemodynamics in patients with neurocirculatory dystonia].
Topics: Adolescent; Adult; Female; gamma-Aminobutyric Acid; Hemodynamics; Humans; Male; Middle Aged; Neurocirculatory Asthenia; Sulpiride; Tachycardia, Paroxysmal | 1983 |
[Disorders in brain levels of macroergic substances during chronic stress and their correction by psychotropic agents].
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biureas; Brain; Chlordiazepoxide; gamma-Aminobutyric Acid; Humans; Lithium; Male; Meprobamate; Rats; Stress, Psychological; Tranquilizing Agents | 1983 |
[Presynaptic component in the mechanism of fenibut action].
Topics: Animals; Baclofen; Bicuculline; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin; Rats; Rats, Inbred Strains; Synaptosomes | 1982 |
[Effect of gamma-aminobutyric acid and its analogs on the smooth muscle of veins].
Topics: Animals; Depression, Chemical; gamma-Aminobutyric Acid; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Pyrrolidinones; Rats | 1980 |
[Experimental basis for clinical study of GABA-positive substances in a threatened pregnancy].
Topics: Abortion, Threatened; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Drug Combinations; Female; gamma-Aminobutyric Acid; Isometric Contraction; Pregnancy; Rabbits; Uterine Contraction | 1994 |
R-(-)-beta-phenyl-GABA is a full agonist at GABAB receptors in brain slices but a partial agonist in the ileum.
Topics: Animals; Brain Chemistry; Cerebral Cortex; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereoisomerism; Tranquilizing Agents | 1993 |
[The effect of phenibut on formation of respiratory rhythm].
Topics: Animals; Baclofen; Cats; Female; GABA Modulators; gamma-Aminobutyric Acid; Hemodynamics; Male; Receptors, GABA; Respiration; Sodium Oxybate | 1995 |
[Sensitivity of the respiratory system to oxygen during activation of brain GABAergic structures].
Topics: Animals; Blood Gas Analysis; Cats; Female; GABA Agonists; gamma-Aminobutyric Acid; Hemodynamics; Hyperoxia; Hypoxia; Male; Oxygen; Receptors, GABA; Respiration; Sodium Oxybate | 1997 |
[The loss of sensitivity of the respiratory system to carbon dioxide during activation of GABAergic brain structures].
Topics: Animals; Brain; Carbon Dioxide; Cats; Female; GABA Agonists; gamma-Aminobutyric Acid; Hemodynamics; Male; Receptors, GABA; Respiration; Respiratory Center; Sodium Oxybate | 1997 |
[Sensitivity of the respiratory system to lung mechanoreceptor impulses during GABAergic system activation].
Topics: Animals; Cats; Female; GABA Agonists; gamma-Aminobutyric Acid; Hemodynamics; Lung; Male; Mechanoreceptors; Receptors, GABA; Respiratory Physiological Phenomena; Sodium Oxybate; Vagotomy | 1999 |
[Neurochemical characteristics of the ventromedial hypothalamus and anti-aversive effects of anxiolytic agents in various anxiety models].
Topics: Adrenergic alpha-Antagonists; Amino Acids; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Biogenic Monoamines; Chlordiazepoxide; Dopamine D2 Receptor Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Harmine; Hypothalamus, Middle; Microinjections; Piperazines; Pyrimidines; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Serotonin Agents | 2001 |
Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Apomorphine; Avoidance Learning; Biguanides; Brain Chemistry; Chlordiazepoxide; Clonidine; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Droperidol; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memantine; Mephenytoin; Microinjections; Pentylenetetrazole; Phentolamine; Picrotoxin; Piperazines; Propranolol; Pyrimidines; Rats; Serotonin; Sulpiride; Ventromedial Hypothalamic Nucleus; Yohimbine | 2003 |
[TRANQUILIZING EFFECTS OF BETA-PHENYL-GAMMA-AMINOBUTYRIC ACID (FENIGAM)].
Topics: Aminobutyrates; Biomedical Research; Body Temperature; Cats; gamma-Aminobutyric Acid; Mice; Movement; Pharmacology; Rabbits; Rats; Research; Toxicology; Tranquilizing Agents | 1964 |
Cyclic GMP protein kinase activity is reduced in thyroxine-induced hypertrophic cardiac myocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Body Weight; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Drug Administration Schedule; Drug Synergism; gamma-Aminobutyric Acid; Guanosine; Heart Ventricles; Hypertrophy; Injections, Intramuscular; Myocardial Contraction; Myocytes, Cardiac; Organ Size; Oxygen Consumption; Phosphoproteins; Phosphorylation; Rabbits; Stimulation, Chemical; Thyroxine; Time Factors | 2003 |
[Effect of the GABA derivative phenibut on learning].
Topics: Animals; Brain; Electroencephalography; GABA Agents; gamma-Aminobutyric Acid; Injections, Subcutaneous; Learning; Rabbits | 2005 |
[Autonomic cardiovascular regulation in patients with tics and Tourette syndrome].
Topics: Anti-Dyskinesia Agents; Anticonvulsants; Autonomic Nervous System Diseases; Child; Clonazepam; Female; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Heart Rate; Humans; Male; Tiapamil Hydrochloride; Tics; Tourette Syndrome; Vagus Nerve Diseases | 2005 |
Neurochemical mechanisms of the dorsal pallidum in the antiaversive effects of anxiolytics in various models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior, Animal; Biogenic Amines; Chlordiazepoxide; Fear; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Harmine; Male; Microinjections; Neurotransmitter Agents; Piperazines; Pyrimidines; Rats; Statistics, Nonparametric | 2006 |
[Peculiarities of nootropic effect of phenibut].
Topics: Animals; Brain; Cognition; gamma-Aminobutyric Acid; Heart Rate; Nootropic Agents; Rabbits | 2006 |
Effect of Citrocard on functional activity of cardiomyocyte mitochondria during chronic alcohol intoxication.
Topics: Alcoholism; Animals; GABA Agents; gamma-Aminobutyric Acid; Male; Mitochondria, Heart; Myocytes, Cardiac; Oxidative Phosphorylation; Oxygen Consumption; Piracetam; Rats | 2007 |
Effect of citrocard on functional reserves of the heart under conditions of chronic stress.
Topics: Animals; Electric Stimulation; gamma-Aminobutyric Acid; Heart; Male; Myocardial Contraction; Rats; Rats, Wistar; Restraint, Physical | 2007 |
[Correction of cardiotoxic effect of chronic alcoholic intoxication by GABA-ergic compounds].
Topics: Alcoholism; Animals; Disease Models, Animal; Drug Therapy, Combination; GABA Agents; gamma-Aminobutyric Acid; Heart; Male; Myocardial Contraction; Nootropic Agents; Piracetam; Rats; Treatment Outcome; Ventricular Pressure | 2007 |
Comparative pharmacological activity of optical isomers of phenibut.
Topics: Analgesics; Animals; Antidepressive Agents; Conflict, Psychological; Depression; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hot Temperature; Male; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Motor Activity; Muscle Strength; Organophosphorus Compounds; Pain Measurement; Postural Balance; Psychomotor Performance; Psychotropic Drugs; Reaction Time; Receptors, GABA-B; Stereoisomerism; Swimming | 2008 |
Effects of the GABA receptor agonist phenibut on behavior and respiration in rabbits in emotionally negative situations.
Topics: Animals; Emotions; Exploratory Behavior; Freezing Reaction, Cataleptic; GABA Agents; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Motor Activity; Rabbits; Respiratory Mechanics; Statistics, Nonparametric; Stress, Psychological | 2008 |
Quantitative analysis of phenibut in rat brain tissue extracts by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Brain Chemistry; Chromatography, Liquid; gamma-Aminobutyric Acid; Male; Rats; Rats, Wistar; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
The effects of agonists of ionotropic GABA(A) and metabotropic GABA(B) receptors on learning.
Topics: Anesthetics; Animals; Behavior, Animal; Brain; Conditioning, Classical; Electroshock; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Isoxazoles; Learning; Motor Activity; Neural Inhibition; Photic Stimulation; Rabbits; Receptors, GABA-B | 2009 |
[Influence of GABA agonist phenibut on the neuronal activity and interaction in hippocampus and neocortex in emotionally negative situations].
Topics: Animals; Emotions; GABA Agents; gamma-Aminobutyric Acid; Hippocampus; Male; Neocortex; Neurons; Rabbits | 2009 |
Comparative study of immunocorrective activity of phenibut and its organic salts in experimental immunodeficiency.
Topics: Adjuvants, Immunologic; Animals; Cyclophosphamide; Female; gamma-Aminobutyric Acid; Immunity, Cellular; Immunity, Humoral; Immunologic Deficiency Syndromes; Immunosuppressive Agents; Lymphocyte Activation; Male; Mice; Mice, Inbred CBA | 2009 |
[Changes in the psycho-emotional state under conditions of suppressed immunogenesis, the correction of the disorders with GABA-positive means].
Topics: Animals; Baclofen; Behavior, Animal; Cyclophosphamide; Emotions; Female; GABA Agonists; gamma-Aminobutyric Acid; Grooming; Immunity; Male; Mice; Mice, Inbred CBA; Rats; Rats, Wistar | 2010 |
[Immune-regulating effect of phenibut under lipopolysaccharide-induced immune stress conditions].
Topics: Animals; Female; gamma-Aminobutyric Acid; Hemagglutination; Hypersensitivity, Delayed; Immune System; Immunity, Cellular; Immunity, Humoral; Immunologic Factors; Lipopolysaccharides; Male; Neutrophils; Phagocytosis; Pseudomonas aeruginosa; Rats; Rats, Wistar; Stress, Physiological | 2010 |
Withdrawal symptoms after Internet purchase of phenibut (β-phenyl-γ-aminobutyric acid HCl).
Topics: Anxiety Disorders; gamma-Aminobutyric Acid; Humans; Internet; Male; Substance Withdrawal Syndrome; Young Adult | 2010 |
[Effects of phenibut on parameters of cerebral hemodynamics in swimmers with dysadaptation syndrome and various types of systemic hemodynamics].
Topics: Athletes; Cerebrovascular Circulation; Child; GABA Agonists; gamma-Aminobutyric Acid; General Adaptation Syndrome; Hemodynamics; Humans; Male; Swimming | 2010 |
[Comparative study of immunomodulating properties of phenibut and gammoxin].
Topics: Animals; Dose-Response Relationship, Drug; Female; GABA Agonists; gamma-Aminobutyric Acid; Immunity, Cellular; Immunity, Humoral; Immunologic Factors; Male; Mice; Mice, Inbred CBA; Spleen; Thymus Gland | 2010 |
[Psychotropic effect of phenibut salts and their compositions with organic acids].
Topics: Animals; Behavior, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Malates; Male; Niacin; Psychotropic Drugs; Rats; Succinic Acid | 2011 |
[Influence of GABA derivatives on some indices of lipid peroxidation in immunocompetent organs under experimental immunopathology conditions].
Topics: Animals; Antioxidants; Baclofen; Catalase; Cyclophosphamide; gamma-Aminobutyric Acid; Immunosuppression Therapy; Immunosuppressive Agents; Lipid Peroxidation; Lipopolysaccharides; Male; Malondialdehyde; Organ Specificity; Oxidative Stress; Piracetam; Rats; Rats, Wistar; Spleen; Thymus Gland | 2011 |
[Effect of new phenibut salts on psychic and physical development of posterity in rats with experimental gestosis].
Topics: Animals; Animals, Newborn; Behavior, Animal; Female; gamma-Aminobutyric Acid; Growth and Development; Pre-Eclampsia; Pregnancy; Rats | 2012 |
[Effect of phenibut and its composition with nicotinic acid on hemostasis in rats with brain ischemia].
Topics: Animals; Anticonvulsants; Brain Ischemia; gamma-Aminobutyric Acid; Hemostasis; Male; Niacin; Rats; Rats, Wistar; Vasodilator Agents | 2012 |
[Fenibut and its citrate prevent psychoneurological disorders caused by chronic stress (paradoxical sleep deprivation)].
Topics: Adrenal Glands; Animals; Avoidance Learning; Behavior, Animal; Citrates; Cognition Disorders; gamma-Aminobutyric Acid; Humans; Male; Maze Learning; Neurotic Disorders; Rats; Sleep Deprivation; Sleep, REM; Stomach; Stress, Physiological; Thymus Gland; Tranquilizing Agents | 2012 |
Phenibut dependence.
Topics: Adult; Baclofen; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Russia; Substance-Related Disorders | 2013 |
[Hepatoduodenal circulation and excretion of the new GABA derivative citrocard].
Topics: Animals; Citric Acid; Duodenum; GABA Agonists; gamma-Aminobutyric Acid; Kidney; Liver; Male; Rats | 2013 |
[Comparative analysis of action of beta-phenyl derivatives of glutamic and gamma-aminobutyric acid on cerebral blood flow and cerebrovascular endothelium after irreversible occlusion of the common carotid artery].
Topics: Animals; Blood Flow Velocity; Brain; Carotid Artery, Common; Cerebrovascular Disorders; Endothelium, Vascular; gamma-Aminobutyric Acid; Glutamic Acid; Male; Protective Agents; Rats; Survival Analysis; Vasodilation; Vasodilator Agents | 2013 |
Changes in oxidant and antioxidant status of females with experimental gestosis under the effect of GABA derivatives.
Topics: Animals; Female; gamma-Aminobutyric Acid; Glutathione Peroxidase; Lipid Peroxidation; Oxidative Stress; Pre-Eclampsia; Pregnancy; Rats; Sodium Chloride; Superoxide Dismutase | 2013 |
Study of the absolute bioavailability of citrocard, a new GABA derivative.
Topics: Animals; Area Under Curve; Biological Availability; GABA Agents; gamma-Aminobutyric Acid; Half-Life; Injections, Intravenous; Male; Rats | 2013 |
Phenibut, the appearance of another potentially dangerous product in the United States.
Topics: Adult; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Substance-Related Disorders; United States | 2014 |
GABA derivatives citrocard and salifen reduce the intensity of experimental gestosis.
Topics: Animals; Blood Pressure; Brain; Female; GABA Agonists; gamma-Aminobutyric Acid; Glycosaminoglycans; Homocysteine; Muscle, Skeletal; Omentum; Pre-Eclampsia; Pregnancy; Rats; Sodium Chloride | 2014 |
[Cardioprotective properties of new glutamic acid derivative under stress conditions].
Topics: Animals; Animals, Outbred Strains; Cardiotonic Agents; Drug Administration Schedule; gamma-Aminobutyric Acid; Glutamic Acid; Heart; Heart Rate; Immobilization; Male; Myocardial Contraction; Pain; Rats; Stress, Physiological | 2014 |
Effect of GABA derivatives on the rate of thrombus formation, platelet aggregation, and plasma coagulation capacity in rats with experimental gestosis.
Topics: Animals; Blood Coagulation; Dipeptides; Female; gamma-Aminobutyric Acid; Glycosaminoglycans; Nicotinic Acids; Platelet Aggregation; Pre-Eclampsia; Pregnancy; Rats; Sodium Chloride; Thrombosis | 2014 |
[Gravidaprotective action of phenibut in experimental pre-eclampsia].
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Female; gamma-Aminobutyric Acid; Lipid Peroxidation; Placenta; Pre-Eclampsia; Pregnancy; Rats; Sodium Chloride; Uterus; Vasodilation | 2014 |
Palladium-catalyzed Cs2CO3-promoted arylation of unactivated C(sp(3))-H bonds by (diacetoxyiodo)arenes: shifting the reactivity of (diacetoxyiodo)arenes from acetoxylation to arylation.
Topics: Carbonates; Catalysis; Cesium; gamma-Aminobutyric Acid; Molecular Structure; Organometallic Compounds; Palladium; Psychotropic Drugs | 2015 |
[Cognitive and emotional impairments in patients with protracted anxiety-phobic disorders].
Topics: Acute Disease; Adolescent; Adult; Chronic Disease; Cognition Disorders; gamma-Aminobutyric Acid; Humans; Middle Aged; Phobic Disorders; Tranquilizing Agents; Treatment Outcome; Young Adult | 2014 |
Multistep continuous-flow synthesis of (R)- and (S)-rolipram using heterogeneous catalysts.
Topics: Antidepressive Agents; Catalysis; Chemistry Techniques, Synthetic; GABA Agonists; gamma-Aminobutyric Acid; Molecular Structure; Rolipram; Stereoisomerism | 2015 |
Effects of Phenibut and Citrocard on Non-Competitive and Competitive Behavior during Provoked Aggression in Animals.
Topics: Agonistic Behavior; Animal Communication; Animals; Avoidance Learning; Baclofen; Competitive Behavior; Drug Evaluation, Preclinical; Electroshock; Escape Reaction; Fear; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Nootropic Agents; Pain; Rats; Tranquilizing Agents | 2015 |
Analytically confirmed recreational use of Phenibut (β-phenyl-γ-aminobutyric acid) bought over the internet.
Topics: Adult; Anxiety Disorders; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Internet; Male | 2015 |
Acute behavioural disturbance associated with phenibut purchased via an internet supplier.
Topics: Adult; Alcohol Drinking; Delirium; Dronabinol; Emergency Service, Hospital; Female; gamma-Aminobutyric Acid; Humans; Internet; Male; Toxicity Tests, Acute; Young Adult | 2015 |
[Neurogenic copulative dysfunction in men: theoretical aspects, differential diagnosis, and rational therapy].
Topics: Adult; Brain Injuries; Diagnosis, Differential; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nootropic Agents; Quality of Life; Radiculopathy; Sexual Dysfunction, Physiological; Tranquilizing Agents; Treatment Outcome | 2015 |
R-phenibut binds to the α2-δ subunit of voltage-dependent calcium channels and exerts gabapentin-like anti-nociceptive effects.
Topics: Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Mice, Inbred ICR; Pain Measurement; Protein Binding; Rats; Rats, Wistar | 2015 |
Phenibut (4-amino-3-phenyl-butyric acid): Availability, prevalence of use, desired effects and acute toxicity.
Topics: Adult; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; Illicit Drugs; Male; Middle Aged; Prevalence; Substance-Related Disorders; Young Adult | 2016 |
Optical isomers of phenibut inhibit [H(3)]-Gabapentin binding in vitro and show activity in animal models of chronic pain.
Topics: Amines; Animals; Chronic Pain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Hypersensitivity; Male; Pain Measurement; Radioligand Assay; Rats; Stereoisomerism | 2016 |
Comparison of Nootropic and Neuroprotective Features of Aryl-Substituted Analogs of Gamma-Aminobutyric Acid.
Topics: Amnesia; Animals; Anticonvulsants; Avoidance Learning; Baclofen; Cinnamates; Coma; Electroshock; gamma-Aminobutyric Acid; Male; Neuroprotective Agents; Nootropic Agents; Rats; Scopolamine | 2016 |
[Emotional and personality disorders in atypical facial pain].
Topics: Adult; Aged; Antidepressive Agents; Anxiety Disorders; Depressive Disorder; Facial Pain; Female; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pain Measurement; Personality Disorders; Personality Inventory; Psychiatric Status Rating Scales; Tranquilizing Agents | 2015 |
[NO-DEPENDENT MECHANISM OF THE CARDIOPROTECTIVE ACTION OF PHENIBUT ON STRESS-INDUCED VIOLATION OF CONTRACTILE FUNCTION OF THE HEART].
Topics: Animals; Cardiotonic Agents; gamma-Aminobutyric Acid; Heart Rate; Male; Myocardial Contraction; Nitric Oxide; Rats; Stress, Psychological | 2015 |
[Tension type headache: GABA-ergic drug anvifen efficacy].
Topics: Adult; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Tension-Type Headache; Treatment Outcome | 2016 |
[THE EFFECT OF PERINATAL HYPOXIA ON THE STRUCTURE OF BLOOD-BRAIN BARRIER IN RATS TREATED WITH SALIFEN].
Topics: Animals; Animals, Newborn; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Endothelium, Vascular; gamma-Aminobutyric Acid; Hypoxia, Brain; Microscopy, Electron; Neuroprotective Agents; Rats | 2015 |
Phenibut overdose.
Topics: Adult; Confusion; Direct-to-Consumer Advertising; Drug Overdose; GABA Agonists; gamma-Aminobutyric Acid; Glasgow Coma Scale; Humans; Internet; Male; Naloxone; Narcotic Antagonists; Stupor | 2017 |
[Protective effects of a new glutamic acid derivative against stress after nNOS blockade].
Topics: Animals; Animals, Outbred Strains; Antioxidants; Brain; Catalase; Drug Synergism; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione Peroxidase; Heart; Immobilization; Indazoles; Lipid Peroxidation; Malondialdehyde; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidative Phosphorylation; Oxidative Stress; Rats; Stress, Psychological | 2017 |
Dissociative Intoxication and Prolonged Withdrawal Associated With Phenibut: A Case Report.
Topics: Adult; Baclofen; Delirium; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Substance Withdrawal Syndrome; Substance-Related Disorders | 2017 |
Effect of Phenibut and Glufimet, a Novel Glutamic Acid Derivative, on Respiration of Heart and Brain Mitochondria from Animals Exposed to Stress against the Background of Inducible NO-Synthase Blockade.
Topics: Animals; Brain; Female; gamma-Aminobutyric Acid; Glutamic Acid; Heart; Mitochondria; Nitric Oxide Synthase Type II; Oxidative Phosphorylation; Rats; Stress, Physiological | 2017 |
Inhibition of the Expression of Inducible NO Synthase by Neuroactive Amino Acid Derivatives Phenibut and Glufimet In Vitro and Ex Vivo.
Topics: Animals; Animals, Outbred Strains; Anti-Inflammatory Agents; Cyclic GMP; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Injections, Intraperitoneal; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Primary Cell Culture | 2017 |
NEUROPROTECTIVE ACTION OF PHENIBUT AND NEUROGLUTAM IN EXPERIMENTAL CEREBRAL ISCHEMIA ON THE BACKGROUND OF ALTERED IMMUNOREACTIVITY.
Topics: Animals; Animals, Outbred Strains; Biomarkers; Brain Ischemia; Carotid Artery, Common; Cerebrovascular Circulation; Cyclosporine; gamma-Aminobutyric Acid; Glutamic Acid; Immunity, Innate; Immunosuppression Therapy; Immunosuppressive Agents; Ligation; Lipopolysaccharides; Locomotion; Male; Muscle Strength; Myelin Basic Protein; Neuroprotective Agents; Orientation, Spatial; Phosphopyruvate Hydratase; Rats; Survival Analysis | 2016 |
Effect of a new cyclic derivative of GABA, RGPU-207, on the functions of cardiac and cerebral mitochondria of stressed animals.
Topics: Acetates; Animals; Antioxidants; Catalase; Cerebral Cortex; Electron Transport; gamma-Aminobutyric Acid; Glutathione Peroxidase; Heart; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Myocardium; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Phenylhydrazines; Piracetam; Pyrrolidinones; Rats; Rats, Wistar; Stress, Psychological; Superoxide Dismutase | 2019 |
Phenibut exposures and clinical effects reported to a regional poison center.
Topics: Adult; Aged; Aged, 80 and over; Central Nervous System Depressants; Drug Overdose; Female; gamma-Aminobutyric Acid; Humans; Incidence; Male; Middle Aged; Minnesota; Poison Control Centers; Retrospective Studies; Risk Factors | 2019 |
Severe phenibut poisoning: An adolescent case cluster.
Topics: Adolescent; gamma-Aminobutyric Acid; Humans; Poisoning | 2020 |
[Phenibut: harmless dietary supplement or dangerous drug?]
Topics: Adult; Dietary Supplements; gamma-Aminobutyric Acid; Humans; Male; Pharmaceutical Preparations; Psychotropic Drugs; Young Adult | 2020 |
Effects of Gaba Derivatives on Anxious and Compulsive Behavior in Offspring of Rats with Experimental Preeclampsia.
Topics: Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Female; GABA Agonists; gamma-Aminobutyric Acid; Male; Obsessive-Compulsive Disorder; Pantothenic Acid; Pre-Eclampsia; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sodium Chloride; Tranquilizing Agents | 2020 |
F-phenibut (β-(4-Fluorophenyl)-GABA), a potent GABA
Topics: Action Potentials; Animals; Baclofen; Dose-Response Relationship, Drug; Female; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice, Inbred ICR; Potassium; Potassium Channels; Purkinje Cells; Receptors, GABA-B | 2020 |
Phenibut Use in a Patient Prescribed Gabapentinoids.
Topics: gamma-Aminobutyric Acid; Humans | 2021 |
Phenibut: A Novel Nootropic With Abuse Potential.
Topics: Adult; gamma-Aminobutyric Acid; Humans; Male; Nootropic Agents; Substance Withdrawal Syndrome; Substance-Related Disorders | 2020 |
Notes from the Field: Phenibut Exposures Reported to Poison Centers - United States, 2009-2019.
Topics: Adolescent; Adult; Female; gamma-Aminobutyric Acid; Humans; Male; Poison Control Centers; Poisoning; United States; Young Adult | 2020 |
Phenibut Dependence and Withdrawal.
Topics: gamma-Aminobutyric Acid; Humans; Substance Withdrawal Syndrome | 2021 |
Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank.
Topics: Drug Overdose; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Oligopeptides; Receptors, GABA; Receptors, Metabotropic Glutamate; Substance Withdrawal Syndrome; Substance-Related Disorders | 2021 |
Quantity of phenibut in dietary supplements before and after FDA warnings.
Topics: Alcoholism; Dietary Supplements; gamma-Aminobutyric Acid; Humans; Substance Withdrawal Syndrome; United States; United States Food and Drug Administration | 2022 |
Chronic Phenibut Use: Symptoms, Severe Withdrawal, and Recovery.
Topics: Adult; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Substance Withdrawal Syndrome | 2022 |
Phenibut and Bromazolam Use Disorders Requiring Hospitalization for Medically Supervised Withdrawal.
Topics: gamma-Aminobutyric Acid; Hospitalization; Humans; Opiate Substitution Treatment; Substance Withdrawal Syndrome | 2022 |
Phenibut withdrawal management in a neonate.
Topics: gamma-Aminobutyric Acid; Humans; Infant, Newborn | 2022 |
Management of Phenibut Use Disorder and Withdrawal in a Geriatric Patient.
Topics: Aged; Benzodiazepines; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Substance-Related Disorders | 2023 |
Experimental Substantiation of the Use of Phenibut Combinations with Salicylic, Nicotinic, and Glutamic Acids in Cerebral Ischemia.
Topics: Animals; Brain Ischemia; Cerebral Infarction; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Rats; Rats, Wistar | 2023 |
Plasma concentrations of phenibut and mitragynine in a single patient.
Topics: gamma-Aminobutyric Acid; Humans; Secologanin Tryptamine Alkaloids | 2023 |