Page last updated: 2024-09-03

4-amino-3-(5-chloro-2-thienyl)butyric acid and baclofen

4-amino-3-(5-chloro-2-thienyl)butyric acid has been researched along with baclofen in 2 studies

Compound Research Comparison

Studies
(4-amino-3-(5-chloro-2-thienyl)butyric acid)
Trials
(4-amino-3-(5-chloro-2-thienyl)butyric acid)
Recent Studies (post-2010)
(4-amino-3-(5-chloro-2-thienyl)butyric acid)
Studies
(baclofen)
Trials
(baclofen)
Recent Studies (post-2010) (baclofen)
6056,0173721,535

Protein Interaction Comparison

ProteinTaxonomy4-amino-3-(5-chloro-2-thienyl)butyric acid (IC50)baclofen (IC50)
Gamma-aminobutyric acid type B receptor subunit 2Homo sapiens (human)0.05
Gamma-aminobutyric acid type B receptor subunit 2Rattus norvegicus (Norway rat)0.2762
Gamma-aminobutyric acid type B receptor subunit 1Homo sapiens (human)0.05
Gamma-aminobutyric acid type B receptor subunit 1Rattus norvegicus (Norway rat)0.2762

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berthelot, P; Brunet, C; Debaert, M; Flouquet, N; Luyckx, M; Vaccher, C1
Brown, KM; Colby, DA; Doerksen, RJ; Hockerman, GH; Roy, KK1

Reviews

1 review(s) available for 4-amino-3-(5-chloro-2-thienyl)butyric acid and baclofen

ArticleYear
Activation of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor by Agonists and Positive Allosteric Modulators.
    Journal of medicinal chemistry, 2015, Aug-27, Volume: 58, Issue:16

    Topics: Animals; GABA Agonists; GABA Antagonists; GABA Modulators; Humans; Molecular Conformation; Receptors, GABA-B; Structure-Activity Relationship

2015

Other Studies

1 other study(ies) available for 4-amino-3-(5-chloro-2-thienyl)butyric acid and baclofen

ArticleYear
3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:8

    Topics: Animals; Baclofen; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Furans; gamma-Aminobutyric Acid; Molecular Structure; Muscimol; Rats; Receptors, GABA-A; Synaptic Membranes; Thiophenes

1991