4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride has been researched along with tropisetron in 3 studies
| Studies (4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride) | Trials (4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride) | Recent Studies (post-2010) (4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride) | Studies (tropisetron) | Trials (tropisetron) | Recent Studies (post-2010) (tropisetron) |
|---|---|---|---|---|---|
| 40 | 1 | 23 | 944 | 218 | 150 |
| Protein | Taxonomy | 4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride (IC50) | tropisetron (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 3.1623 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 3.1623 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 3.45 | |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | 1.8 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.488 | |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | 1.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bachy, A; Emerit, MB; Giudice, A; Gozlan, H; Hamon, M; Héaulme, M; Lefevre, IA; Manara, L; Michaud, JC; Souilhac, J | 1 |
| Abdel-Aziz, H; Ploch, M; Verspohl, EJ; Windeck, T | 1 |
| Ali, U; Feng, JJ; Gui, ZH; Hui, YP; Li, LB; Liu, J; Niu, XL; Wu, ZH; Zhang, QJ | 1 |
3 other study(ies) available for 4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride and tropisetron
| Article | Year |
|---|---|
SR 57227A: a potent and selective agonist at central and peripheral 5-HT3 receptors in vitro and in vivo.
Topics: Animals; Blood-Brain Barrier; Brain; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Guinea Pigs; Ileum; Indoles; Male; Mice; Muscle Contraction; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P; Tropisetron | 1993 |
Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum.
Topics: Animals; Binding, Competitive; Carbon Radioisotopes; Catechols; Cations; Cell Line, Tumor; Dose-Response Relationship, Drug; Fatty Alcohols; Guanidine; Guinea Pigs; Humans; Ileum; Imidazoles; In Vitro Techniques; Indoles; Ion Channels; Isotonic Contraction; Male; Mice; Organic Cation Transport Proteins; Piperidines; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Sodium Channels; Substance P; Tritium; Tropisetron; Veratridine; Zingiber officinale | 2006 |
The pyramidal neurons in the medial prefrontal cortex show decreased response to 5-hydroxytryptamine-3 receptor stimulation in a rodent model of Parkinson's disease.
Topics: Action Potentials; Analysis of Variance; Animals; Bicuculline; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; Indoles; Male; Oxidopamine; Parkinson Disease; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Serotonin Agents; Statistics, Nonparametric; Substantia Nigra; Tropisetron; Tyrosine 3-Monooxygenase | 2011 |