4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride and substance p

4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride has been researched along with substance p in 2 studies

Compound Research Comparison

Studies (4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride)	Trials (4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride)	Recent Studies (post-2010) (4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride)	Studies (substance p)	Trials (substance p)	Recent Studies (post-2010) (substance p)
40	1	23	17,289	277	2,010

Protein Interaction Comparison

Protein	Taxonomy	substance p (IC50)
Substance-P receptor	Rattus norvegicus (Norway rat)	0.0005
Substance-K receptor	Rattus norvegicus (Norway rat)	0.2
Substance-K receptor	Homo sapiens (human)	0.2455
Substance-P receptor	Homo sapiens (human)	0.0011
Neuromedin-K receptor	Homo sapiens (human)	0.125
Substance-K receptor	Mesocricetus auratus (golden hamster)	0.148

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bachy, A; Emerit, MB; Giudice, A; Gozlan, H; Hamon, M; Héaulme, M; Lefevre, IA; Manara, L; Michaud, JC; Souilhac, J	1
Abdel-Aziz, H; Ploch, M; Verspohl, EJ; Windeck, T	1

Other Studies

2 other study(ies) available for 4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride and substance p

Article	Year
SR 57227A: a potent and selective agonist at central and peripheral 5-HT3 receptors in vitro and in vivo. European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3 Topics: Animals; Blood-Brain Barrier; Brain; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Guinea Pigs; Ileum; Indoles; Male; Mice; Muscle Contraction; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P; Tropisetron	1993
Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum. European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2 Topics: Animals; Binding, Competitive; Carbon Radioisotopes; Catechols; Cations; Cell Line, Tumor; Dose-Response Relationship, Drug; Fatty Alcohols; Guanidine; Guinea Pigs; Humans; Ileum; Imidazoles; In Vitro Techniques; Indoles; Ion Channels; Isotonic Contraction; Male; Mice; Organic Cation Transport Proteins; Piperidines; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Sodium Channels; Substance P; Tritium; Tropisetron; Veratridine; Zingiber officinale	2006

Article

Year

SR 57227A: a potent and selective agonist at central and peripheral 5-HT3 receptors in vitro and in vivo.

European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3

Topics: Animals; Blood-Brain Barrier; Brain; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Guinea Pigs; Ileum; Indoles; Male; Mice; Muscle Contraction; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P; Tropisetron

1993

Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum.

European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

Topics: Animals; Binding, Competitive; Carbon Radioisotopes; Catechols; Cations; Cell Line, Tumor; Dose-Response Relationship, Drug; Fatty Alcohols; Guanidine; Guinea Pigs; Humans; Ileum; Imidazoles; In Vitro Techniques; Indoles; Ion Channels; Isotonic Contraction; Male; Mice; Organic Cation Transport Proteins; Piperidines; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Sodium Channels; Substance P; Tritium; Tropisetron; Veratridine; Zingiber officinale

2006