Page last updated: 2024-09-03

4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride and ondansetron

4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride has been researched along with ondansetron in 2 studies

Compound Research Comparison

Studies
(4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride)
Trials
(4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride)
Recent Studies (post-2010)
(4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride)
Studies
(ondansetron)
Trials
(ondansetron)
Recent Studies (post-2010) (ondansetron)
401233,3801,216994

Protein Interaction Comparison

ProteinTaxonomy4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride (IC50)ondansetron (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)10
Solute carrier family 22 member 2Homo sapiens (human)1.295
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)10
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)10
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)10
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)10
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)10
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)10
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)10
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)10
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)10
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)10
5-hydroxytryptamine receptor 3ARattus norvegicus (Norway rat)0.0136
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.717
5-hydroxytryptamine receptor 3AHomo sapiens (human)0.0001
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)10
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)10
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)10
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.7303
Multidrug and toxin extrusion protein 2Homo sapiens (human)2.4533
GABA theta subunitRattus norvegicus (Norway rat)10
Multidrug and toxin extrusion protein 1Homo sapiens (human)0.0875
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)10
5-hydroxytryptamine receptor 3BRattus norvegicus (Norway rat)0.0181

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cui, R; Dong, X; Li, B; Liu, C; Lv, J; Shao, D; Song, Y; Sun, Z; Wang, L; Wang, P; Zhang, X; Zhao, J; Zhou, Y1
Kurosawa, N; Seki, K; Shimizu, K1

Other Studies

2 other study(ies) available for 4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride and ondansetron

ArticleYear
The anticonvulsant effects of SR 57227 on pentylenetetrazole-induced seizure in mice.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Animals; Anticonvulsants; gamma-Aminobutyric Acid; Hippocampus; Male; Mice, Inbred ICR; Ondansetron; Pentylenetetrazole; Piperidines; Proto-Oncogene Proteins c-fos; Seizures; Survival Analysis

2014
The role of the AMPA receptor and 5-HT(3) receptor on aggressive behavior and depressive-like symptoms in chronic social isolation-reared mice.
    Physiology & behavior, 2016, Jan-01, Volume: 153

    Topics: Aggression; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Depression; Food Preferences; Glutamate Decarboxylase; Hypothalamus; Injections, Intraperitoneal; Male; Mice; Microinjections; Motor Activity; Neurons; Ondansetron; Piperidines; Quinoxalines; Receptors, AMPA; Receptors, Serotonin, 5-HT3; Social Isolation

2016