Compounds > 4,7,10,13-eicosatetraynoic acid
Page last updated: 2024-09-05

4,7,10,13-eicosatetraynoic acid and indomethacin

4,7,10,13-eicosatetraynoic acid has been researched along with indomethacin in 4 studies

Compound Research Comparison

Studies
(4,7,10,13-eicosatetraynoic acid)		Trials
(4,7,10,13-eicosatetraynoic acid)		Recent Studies (post-2010)
(4,7,10,13-eicosatetraynoic acid)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
110029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomy4,7,10,13-eicosatetraynoic acid (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Parthasarathy, S; Steinberg, D; Wieland, E1
Kishore, NP; Rao, GH; White, JG1
Knepel, W; Vlaskovska, M1
Baehner, RL; Boxer, LA; Clarke, MF; Ingraham, LM; Weening, RS1

Other Studies

4 other study(ies) available for 4,7,10,13-eicosatetraynoic acid and indomethacin

ArticleYear
A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta; Aspirin; Cells, Cultured; Copper; Endothelium, Vascular; Humans; Indomethacin; Lipoproteins, LDL; Lipoxygenase; Masoprocol; Oxidation-Reduction; Rabbits; Recombinant Proteins; Superoxide Dismutase; Superoxides

1989
Differential effects of putative inhibitors on cytosolic and membrane associated platelet lipoxygenase.
    Prostaglandins, leukotrienes, and medicine, 1987, Volume: 26, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Adult; Arachidonate Lipoxygenases; Blood Platelets; Cell Membrane; Cytosol; Humans; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Prostaglandin Antagonists; Pyrazoles; Quercetin; Substrate Specificity; Umbelliferones

1987
Beta-endorphin and adrenocorticotropin release from rat adenohypophysis in vitro: evidence for local modulation by arachidonic acid metabolites of the cyclooxygenase and lipoxygenase pathway.
    Neuroendocrinology, 1984, Volume: 39, Issue:4

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Adrenocorticotropic Hormone; Animals; Arachidonic Acids; beta-Endorphin; Catechols; Dinoprostone; Endorphins; In Vitro Techniques; Indomethacin; Male; Masoprocol; Pituitary Gland, Anterior; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains

1984
Relation of respiratory burst and arachidonate metabolism during phagocytosis by guinea pig alveolar macrophages.
    The Journal of laboratory and clinical medicine, 1982, Volume: 99, Issue:6

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Aspirin; Guinea Pigs; Indomethacin; Macrophage Activation; Macrophages; Oxygen Consumption; Phagocytosis; Superoxides; Zymosan

1982