4-6-cholestadien-3-one and cholest-4-en-3-one
4-6-cholestadien-3-one has been researched along with cholest-4-en-3-one* in 1 studies
Other Studies
1 other study(ies) available for 4-6-cholestadien-3-one and cholest-4-en-3-one
Article | Year |
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The cholesterol metabolite cholest-4-en-3-one and its 3-oxo derivatives suppress body weight gain, body fat accumulation and serum lipid concentration in mice.
Based on the findings that cholest-4-en-3-one, an intestinal metabolite of cholesterol, has an anti-obesity effect on animals, the structure-effect relationship of its 3-oxo derivatives and related compounds were investigated. Cholesten-3-ones, which possesses an enone structure with a carbonyl group at C3, markedly inhibit body weight gain and body fat accumulation, as well as the levels of serum triglyceride and cholesterol in animals without any clinical abnormalities. Topics: Adipose Tissue; Animals; Cholestenones; Cholesterol; Drug Design; Lipids; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Molecular Structure; Organ Size; Structure-Activity Relationship; Weight Gain | 1998 |