4-4-difluoro-4-bora-3a-4a-diaza-s-indacene and pyrimidine

4-4-difluoro-4-bora-3a-4a-diaza-s-indacene has been researched along with pyrimidine* in 1 studies

Other Studies

1 other study(ies) available for 4-4-difluoro-4-bora-3a-4a-diaza-s-indacene and pyrimidine

Article	Year
High activity, high selectivity and high biocompatibility BODIPY-pyrimidine derivatives for fluorescence target recognition and evaluation of inhibitory activity. Bioorganic chemistry, 2021, Volume: 114 BODIPY-Pyrimidine (BP) is a highly selective, highly active, and highly biocompatible fluorescent drug, which is characterized by its own activity combined with a fluorophore. The combination of pyrimidines with good biological activity and fluorophores to obtain new compounds with both anti-tumor activity and fluorescent targeting probe functions is the focus of this research. In terms of biological activity, in vitro cytotoxicity of the compounds on four human cancer cells (HepG2, HeLa, A-459, and HCT-116) and the human normal cell line L-02 was studied. BP-4 has good antiproliferative activity, and its IC Topics: Antineoplastic Agents; Apoptosis; Biocompatible Materials; Boron Compounds; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Fluorescence; Fluorescent Dyes; Humans; Molecular Docking Simulation; Molecular Structure; Optical Imaging; Pyrimidines; Structure-Activity Relationship	2021

Article

Year

High activity, high selectivity and high biocompatibility BODIPY-pyrimidine derivatives for fluorescence target recognition and evaluation of inhibitory activity.

Bioorganic chemistry, 2021, Volume: 114

BODIPY-Pyrimidine (BP) is a highly selective, highly active, and highly biocompatible fluorescent drug, which is characterized by its own activity combined with a fluorophore. The combination of pyrimidines with good biological activity and fluorophores to obtain new compounds with both anti-tumor activity and fluorescent targeting probe functions is the focus of this research. In terms of biological activity, in vitro cytotoxicity of the compounds on four human cancer cells (HepG2, HeLa, A-459, and HCT-116) and the human normal cell line L-02 was studied. BP-4 has good antiproliferative activity, and its IC

Topics: Antineoplastic Agents; Apoptosis; Biocompatible Materials; Boron Compounds; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Fluorescence; Fluorescent Dyes; Humans; Molecular Docking Simulation; Molecular Structure; Optical Imaging; Pyrimidines; Structure-Activity Relationship

2021