4,4-dicarboxy-5-pyridoxylproline has been researched along with 1-(2-methoxyphenyl)piperazine in 3 studies
*1-(2-methoxyphenyl)piperazine: RN given refers to parent cpd [MeSH]
*1-(2-methoxyphenyl)piperazine: RN given refers to parent cpd [MeSH]
| Studies (4,4-dicarboxy-5-pyridoxylproline) | Trials (4,4-dicarboxy-5-pyridoxylproline) | Recent Studies (post-2010) (4,4-dicarboxy-5-pyridoxylproline) | Studies (1-(2-methoxyphenyl)piperazine) | Trials (1-(2-methoxyphenyl)piperazine) | Recent Studies (post-2010) (1-(2-methoxyphenyl)piperazine) |
|---|---|---|---|---|---|
| 9 | 0 | 4 | 52 | 0 | 18 |
| Protein | Taxonomy | 4,4-dicarboxy-5-pyridoxylproline (IC50) | 1-(2-methoxyphenyl)piperazine (IC50) |
|---|---|---|---|
| Beta-1 adrenergic receptor | Homo sapiens (human) | 2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banala, AK; Beuming, T; Cao, J; Donthamsetti, P; Javitch, JA; LaBounty, A; Levy, B; Luedtke, RR; Michino, M; Newman, AH; Pongetti, K; Shi, L | 1 |
| Butini, S; Campiani, G; Gemma, S | 1 |
| Capuano, B; Christopoulos, A; Klein Herenbrink, C; Lane, JR; Szabo, M | 1 |
3 other study(ies) available for 4,4-dicarboxy-5-pyridoxylproline and 1-(2-methoxyphenyl)piperazine
| Article | Year |
|---|---|
Molecular determinants of selectivity and efficacy at the dopamine D3 receptor.
Topics: Computer Simulation; HEK293 Cells; Humans; Molecular Conformation; Molecular Dynamics Simulation; Piperazines; Radioligand Assay; Receptors, Dopamine D2; Receptors, Dopamine D3; Static Electricity; Structure-Activity Relationship | 2012 |
A straightforward approach for engineering efficacy and selectivity at GPCRs.
Topics: Humans; Piperazines; Receptors, Dopamine D3 | 2012 |
Structure-activity relationships of privileged structures lead to the discovery of novel biased ligands at the dopamine Dâ‚‚ receptor.
Topics: Animals; CHO Cells; Cricetulus; Cyclic AMP; Dopamine D2 Receptor Antagonists; Drug Partial Agonism; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Piperazines; Piperidines; Radioligand Assay; Receptors, Dopamine D2; Structure-Activity Relationship; Thienopyridines | 2014 |