4,4'-diphenylmethane diisocyanate and toluene 2,4-diisocyanate

4,4'-diphenylmethane diisocyanate has been researched along with toluene 2,4-diisocyanate in 66 studies

Research

Studies (66)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (37.88)	18.7374
1990's	15 (22.73)	18.2507
2000's	16 (24.24)	29.6817
2010's	7 (10.61)	24.3611
2020's	3 (4.55)	2.80

Authors

Authors	Studies
Akimoto, T; Dambara, T; Kira, S; Nukiwa, T; Tamura, N; Uchida, K	1
Arai, Y; Fukushima, N; Hosojima, T; Matsuzaki, G; Miyamoto, Y; Sano, Y; Suko, M; Suzuki, N	1
Baur, X; Fruhmann, G; Vogelmeier, C	1
Cartier, A; Grammer, LC; Harris, KE; Malo, JL; Patterson, R	1
Belin, L; Wass, U	1
Arakawa, M; Kioi, S; Nozawa, S; Sasagawa, M; Sato, T; Suzuki, E	1
Hanada, S; Nishimura, F; Takeoka, A; Tanaka, K	1
Cirla, AM; Innocenti, A; Mariano, A; Pisati, G	1
Gee, JB; Morgan, WK	1
Boschetto, P; Dal Vecchio, L; Fabbri, LM; Mapp, CE	1
Purnell, CJ; Walker, RF	1
Berstein, L; Musk, AW; Peters, JM	1
Ito, T; Kudo, T; Miki, T; Shima, S; Tachikawa, S; Yoshida, T	1
Banks, DE; Butcher, BT; Salvaggio, JE	1
Mäki-Paakkanen, J; Norppa, H	1
Filieri, M; Gerosa, F; Paggiaro, P; Pezzini, A; Riviera, A; Spiazzi, A; Toma, G; Tridente, G	1
Bellone, JD; Kanellakes, TM; Levitz, D; Patterson, R; Pruzansky, JJ; Zeiss, CR	1
Tanaka, K	1
Baur, X; Fruhmann, G	1
Woolrich, PF	1
Hurst, DJ	1
Andersen, M; Binderup, M; Kiel, P; Larsen, H; Maxild, J	1
DiBerardinis, L; Murphy, RL; Musk, AW; Peters, JM	1
Baur, X	1
Butcher, BT	1
Burge, PS	1
Ayers, TA; Bishop, RW; Esposito, GG	1
Wang, SR; Wang, SS	1
Baur, X; Dewair, M; Mauermayer, R	1
Bernstein, DI; Herd, ZL	1
Blaikie, L; Botham, PA; Hartop, PJ; Hext, P; Morrow, T; Rattray, NJ; Wilson, AP; Woodcock, D	1
Calcagni, PG; Di Stefano, A; Fabbri, LM; Hosselet, JJ; Maestrelli, P; Mapp, CE; Saetta, M; Santonastaso, A	1
Hagmar, L; Mikoczy, Z; Strömberg, U; Welinder, H	1
Baur, X; Czuppon, AB; Hartmann, R; Marczynski, B; Scheer, E	1
Hagmar, L; Mikoczy, Z; Welinder, H	1
Baur, X; Marczynski, B; Peel, M	1
Alam, R; Bernstein, DI; Bernstein, JA; Lummus, ZL	1
Herbold, B; Kopp, R; Seel, K; Walber, U	1
Baur, X; Marczynski, B; Marek, W; Mensing, T; Potthast, J	1
Aul, DJ; Bhaumik, A; Brown, WE; Kennedy, AL; Lesage, J; Malo, JL	1
Choi, IS; Jang, AS; Koh, YI; Lee, KJ; Moon, JD	1
Keskinen, HM; Luukkonen, R; Nordman, H; Piirilä, PL; Salo, SP; Tuomi, TO; Tuppurainen, M	1
Estlander, T; Jolanki, R; Kanerva, L; Keskinen, H	1
Beckett, PN; Curran, AD; Elms, J; Griffin, P	1
Hayashi, M; Higashi, K; Kaneko, H; Kato, H	1
Baur, X; Bolognesi, C; Marczynski, B; Norppa, H; Sabbioni, G; Sepai, O	1
Redlich, CA; Wisnewski, AV	1
Gordon, T; Redlich, CA; Wisnewski, AV	1
Bailey, RE; Pemberton, D; Tury, B	1
Colmsjö, A; Johansson, R; Karlsson, D; Låstbom, L; Melin, J; Nordqvist, Y; Skarping, G	1
Liu, Q; Wisnewski, AV	1
Bracht, A; Brüning, T; Haufs, MG; Käfferlein, HU; Kappler, M; Marczynski, B; Mensing, T; Merget, R; Rabstein, S	1
Bruze, M; Frick-Engfeldt, M; Isaksson, M; Karlsson, D; Marand, A; Skarping, G; Zimerson, E	1
Bernstein, DI; Graham, C; Lummus, Z; Ott, MG; Woolhiser, M	1
Batlle, R; Crescenzi, C; López, P; Nerín, C	1
Lammintausta, K; Liippo, J	1
Ehnes, C; Fabian, E; Gamer, A; Hoffmann, HD; Landsiedel, R; Leibold, E; Poole, A	1
Ahonen, N; Järvelä, M; Järventaus, H; Korpi, A; Lindberg, HK; Norppa, H; Pasanen, AL; Rosenberg, C; Säkkinen, K; Santonen, T; Tornaeus, J	1
Aalto-Korte, K; Henriks-Eckerman, ML; Jolanki, R; Kuuliala, O; Suuronen, K	1
Bernstein, DI; Boulet, LP; Cartier, A; Cruz, MJ; Fluharty, K; Gautrin, D; Germolec, DR; Johnson, VJ; Kissling, GE; Lummus, ZL; Luster, MI; Malo, JL; Munoz, X; Quirce, S; Sastre, J; Tarlo, SM; Yucesoy, B	1
Broberg, K; Jönsson, BA; Lindh, CH; Tinnerberg, H	1
Beezhold, DH; Bledsoe, TA; Green, BJ; Lemons, AR; Siegel, PD	1
De Vooght, V; Devos, F; Hoet, PH; Nemery, B; Pollaris, L; Seys, S; Vanoirbeek, JA	1
Aubin, S; Breau, L; Donchenko, A; Gagné, S; Lesage, J; Spence, M	1
Plehiers, PM; Schupp, T	1
Aerts, O; Dendooven, E; Foubert, K; Lambert, J; Naessens, T; Pieters, L	1

Reviews

9 review(s) available for 4,4'-diphenylmethane diisocyanate and toluene 2,4-diisocyanate

Article	Year
[A case of hypersensitivity pneumonitis due to isocyanate (TDI)]. Nihon Kyobu Shikkan Gakkai zasshi, 1989, Volume: 27, Issue:11 Topics: Alveolitis, Extrinsic Allergic; Cyanates; Humans; Infusions, Intravenous; Isocyanates; Male; Methylprednisolone; Middle Aged; Occupational Diseases; Skin Tests; Toluene 2,4-Diisocyanate	1989
Methods for the determination of atmospheric organic isocyanates. A review. The Analyst, 1985, Volume: 110, Issue:8 Topics: Air Pollutants; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Colorimetry; Cyanates; Humans; Isocyanates; Occupational Diseases; Spectrophotometry, Infrared; Toluene 2,4-Diisocyanate	1985
Isocyanate-induced respiratory disease. Annals of allergy, 1986, Volume: 57, Issue:6 Topics: Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Occupational Diseases; Respiratory Hypersensitivity; Respiratory System; Toluene 2,4-Diisocyanate	1986
Toxicology, industrial hygiene and medical control of TDI, MDI and PMPPI. American Industrial Hygiene Association journal, 1982, Volume: 43, Issue:2 Topics: Animals; Chemical Phenomena; Chemistry; Cyanates; Humans; Isocyanates; Maximum Allowable Concentration; Occupational Diseases; Polymers; Toluene 2,4-Diisocyanate	1982
Carcinogenic risk of toluene diisocyanate and 4,4'-methylenediphenyl diisocyanate: epidemiological and experimental evidence. Critical reviews in toxicology, 2001, Volume: 31, Issue:6 Topics: Animals; Blood Proteins; Carcinogenicity Tests; Carcinogens; Chemical Industry; DNA Adducts; Female; Humans; Isocyanates; Male; Mutagenicity Tests; Neoplasms; Occupational Exposure; Protein Binding; Salmonella typhimurium; Toluene 2,4-Diisocyanate	2001
Recent developments in diisocyanate asthma. Current opinion in allergy and clinical immunology, 2001, Volume: 1, Issue:2 Topics: Asthma; Cyanates; Genes, MHC Class II; Genetic Predisposition to Disease; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Skin; T-Lymphocytes, Helper-Inducer; Toluene 2,4-Diisocyanate	2001
Mouse models of diisocyanate asthma. American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:4 Topics: Allergens; Animals; Asthma; Cyanates; Disease Models, Animal; Isocyanates; Mice; Models, Biological; Models, Chemical; Toluene 2,4-Diisocyanate	2002
Recent developments in diisocyanate asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:5 Suppl 2 Topics: Asthma; Cyanates; Epithelial Cells; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Isocyanates; Lung; Occupational Diseases; Occupational Exposure; Skin; Toluene 2,4-Diisocyanate	2003
Absorption, distribution, metabolism, and excretion of methylene diphenyl diisocyanate and toluene diisocyanate: Many similarities and few differences. Toxicology and industrial health, 2022, Volume: 38, Issue:9 Topics: Asthma; Chemical Phenomena; Humans; Isocyanates; Toluene 2,4-Diisocyanate	2022

Other Studies

57 other study(ies) available for 4,4'-diphenylmethane diisocyanate and toluene 2,4-diisocyanate

Article	Year
[A case of hypersensitivity pneumonitis due to isocyanate exposure showing progression even two months after removal of the antigen]. Nihon Kyobu Shikkan Gakkai zasshi, 1992, Volume: 30, Issue:3 Topics: Aged; Alveolitis, Extrinsic Allergic; Cyanates; Humans; Isocyanates; Male; Occupational Exposure; Paint; Toluene 2,4-Diisocyanate	1992
[A case of hypersensitivity pneumonitis in which serum specific antibodies for three species of isocyanate molecules were demonstrated]. Nihon Kyobu Shikkan Gakkai zasshi, 1992, Volume: 30, Issue:3 Topics: Alveolitis, Extrinsic Allergic; Antibodies; Cyanates; Humans; Isocyanates; Male; Middle Aged; Paint; Toluene 2,4-Diisocyanate	1992
Isocyanate-induced asthma: results of inhalation tests with TDI, MDI and methacholine. International archives of occupational and environmental health, 1991, Volume: 63, Issue:1 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Isocyanates; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate	1991
The use of an immunoassay index for antibodies against isocyanate human protein conjugates and application to human isocyanate disease. The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:1 Topics: Antibodies; Antibody Specificity; Blood Proteins; Cyanates; Enzyme-Linked Immunosorbent Assay; Haptens; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate	1990
Immunologic specificity of isocyanate-induced IgE antibodies in serum from 10 sensitized workers. The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:1 Topics: Antibody Specificity; Asthma; Carrier Proteins; Cyanates; Haptens; Humans; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Toluene 2,4-Diisocyanate	1989
Contact sensitivity induced in mice by methylene bisphenyl diisocyanate. Contact dermatitis, 1987, Volume: 17, Issue:4 Topics: Administration, Cutaneous; Animals; Cross Reactions; Cyanates; Dermatitis, Contact; Disease Models, Animal; Hypersensitivity, Delayed; Immunization, Passive; Isocyanates; Male; Mice; Mice, Inbred C57BL; T-Lymphocytes; Toluene 2,4-Diisocyanate	1987
Cross-reaction between aromatic isocyanates (TDI and MDI): a specific bronchial provocation test study. Clinical allergy, 1988, Volume: 18, Issue:4 Topics: Adult; Asthma; Bronchial Provocation Tests; Cross Reactions; Cyanates; Female; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate	1988
A 10-year follow-up study of a group of workers exposed to isocyanates. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1985, Volume: 27, Issue:1 Topics: Adult; Cyanates; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Isocyanates; Lung Diseases, Obstructive; Male; Middle Aged; Occupational Diseases; Smoking; Time Factors; Toluene 2,4-Diisocyanate; Vital Capacity	1985
Combined asthma and alveolitis due to diphenylmethane diisocyanate (MDI) with demonstration of no crossed respiratory reactivity to toluene diisocyanate (TDI). Annals of allergy, 1985, Volume: 54, Issue:5 Topics: Adult; Alveolitis, Extrinsic Allergic; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Neutrophils; Therapeutic Irrigation; Toluene 2,4-Diisocyanate	1985
Absence of respiratory effects in subjects exposed to low concentrations of TDI and MDI: a reevaluation. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1985, Volume: 27, Issue:12 Topics: Cyanates; Environmental Exposure; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Respiration; Toluene 2,4-Diisocyanate; Vital Capacity	1985
[Health hazards in workers of small scale polyurethane production factory]. Sangyo igaku. Japanese journal of industrial health, 1986, Volume: 28, Issue:2 Topics: Adolescent; Adult; Aged; Asthma; Chemical Industry; Cyanates; Female; Humans; Isocyanates; Male; Middle Aged; Morbidity; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate	1986
Chromosome aberrations and sister-chromatid exchanges induced by technical grade toluene diisocyanate and methylenediphenyl diisocyanate in cultured human lymphocytes. Toxicology letters, 1987, Volume: 36, Issue:1 Topics: Animals; Cells, Cultured; Chromosome Aberrations; Cyanates; Humans; Isocyanates; Lymphocytes; Rats; Sister Chromatid Exchange; Toluene 2,4-Diisocyanate	1987
Specific IgE antibodies in twenty-eight workers with diisocyanate-induced bronchial asthma. Clinical allergy, 1984, Volume: 14, Issue:5 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Toluene 2,4-Diisocyanate	1984
Immunoglobulin E-mediated asthma and hypersensitivity pneumonitis with precipitating anti-hapten antibodies due to diphenylmethane diisocyanate (MDI) exposure. The Journal of allergy and clinical immunology, 1980, Volume: 65, Issue:5 Topics: Adult; Alveolitis, Extrinsic Allergic; Antibodies; Asthma; Benzhydryl Compounds; Cross Reactions; Cyanates; Haptens; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Male; Middle Aged; Serum Albumin; Toluene 2,4-Diisocyanate	1980
Contact sensitivity in mice induced by tolylene diisocyanate (TDI). The Journal of dermatology, 1980, Volume: 7, Issue:4 Topics: Animals; Benzhydryl Compounds; Cross Reactions; Cyanates; Dermatitis, Contact; Humans; Isocyanates; Mice; Mice, Inbred C3H; Thymectomy; Toluene 2,4-Diisocyanate	1980
Specific IgE antibodies in patients with isocyanate asthma. Chest, 1981, Volume: 80, Issue:1 Suppl Topics: Antibodies; Asthma; Benzhydryl Compounds; Cyanates; Humans; Immunoglobulin E; Isocyanates; Toluene 2,4-Diisocyanate	1981
Occupational asthma. The Journal of laboratory and clinical medicine, 1982, Volume: 99, Issue:5 Topics: Animals; Asthma; Bronchi; Cyanates; Dogs; Humans; Isocyanates; Occupational Diseases; Radioallergosorbent Test; Toluene 2,4-Diisocyanate	1982
Isocyanates represent a serious health hazard. Scandinavian journal of work, environment & health, 1982, Volume: 8, Issue:1 Topics: Animals; Cyanates; Isocyanates; Toluene 2,4-Diisocyanate	1982
Absence of respiratory effects in subjects exposed to low concentrations of TDI and MDI. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1982, Volume: 24, Issue:10 Topics: Air Pollutants; Air Pollutants, Occupational; Cyanates; Female; Humans; Isocyanates; Lung; Male; Maximal Expiratory Flow Rate; Smoking; Time Factors; Toluene 2,4-Diisocyanate	1982
Immunologic cross-reactivity between different albumin-bound isocyanates. The Journal of allergy and clinical immunology, 1983, Volume: 71, Issue:2 Topics: Adult; Aerosols; Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate	1983
Isocyanate induced asthma. European journal of respiratory diseases. Supplement, 1982, Volume: 123 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Forced Expiratory Volume; Humans; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate	1982
Non-specific bronchial hyper-reactivity in workers exposed to toluene di-isocyanate, diphenyl methane di-isocyanate and colophony. European journal of respiratory diseases. Supplement, 1982, Volume: 123 Topics: Asthma; Bronchi; Cyanates; Electronics; Environmental Exposure; Histamine; Humans; Isocyanates; Occupational Diseases; Resins, Plant; Toluene 2,4-Diisocyanate	1982
A gas chromatographic procedure for the determination of airborne MDI and TDI. American Industrial Hygiene Association journal, 1983, Volume: 44, Issue:3 Topics: Air; Air Pollutants; Chromatography, Gas; Cyanates; Isocyanates; Toluene 2,4-Diisocyanate	1983
[Asthma induced by diphenylmethane diisocyanate]. Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology, 1983, Volume: 16, Issue:1 Topics: Adult; Asthma; Chemical Phenomena; Chemistry; Cyanates; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Risk; Toluene 2,4-Diisocyanate	1983
Inhibition of acetylcholinesterase by diisocyanates and its spontaneous reactivation. International archives of occupational and environmental health, 1983, Volume: 52, Issue:3 Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cyanates; Dose-Response Relationship, Drug; Environmental Exposure; Erythrocytes; Humans; In Vitro Techniques; Isocyanates; Risk; Software; Toluene 2,4-Diisocyanate	1983
Antigen-specific stimulation of histamine releasing factors in diisocyanate-induced occupational asthma. American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:4 Topics: Allergens; Antibody Specificity; Asthma; Biomarkers; Biomarkers, Tumor; Cells, Cultured; Dose-Response Relationship, Immunologic; Epitopes; Female; Histamine Release; Humans; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Occupational Diseases; Statistics, Nonparametric; Toluene 2,4-Diisocyanate; Tumor Protein, Translationally-Controlled 1	1994
A two-centre study for the evaluation and validation of an animal model for the assessment of the potential of small molecular weight chemicals to cause respiratory allergy. Toxicology, 1995, Jan-19, Volume: 96, Issue:1 Topics: Administration, Inhalation; Allergens; Animals; Antibody Specificity; Antigen-Antibody Complex; Dinitrochlorobenzene; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Haptens; Injections, Intradermal; Isocyanates; Male; Molecular Weight; Phthalic Anhydrides; Respiration; Respiratory Hypersensitivity; Serum Albumin; Toluene 2,4-Diisocyanate	1995
Sputum eosinophilia after asthmatic responses induced by isocyanates in sensitized subjects. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1994, Volume: 24, Issue:1 Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Eosinophilia; Female; Humans; Isocyanates; Leukocyte Count; Male; Occupational Diseases; Sputum; Toluene 2,4-Diisocyanate	1994
Incidence of cancer and exposure to toluene diisocyanate and methylene diphenyldiisocyanate: a cohort based case-referent study in the polyurethane foam manufacturing industry. British journal of industrial medicine, 1993, Volume: 50, Issue:11 Topics: Case-Control Studies; Cohort Studies; Humans; Incidence; Isocyanates; Male; Neoplasms; Occupational Diseases; Occupational Exposure; Polyurethanes; Prostatic Neoplasms; Sweden; Toluene 2,4-Diisocyanate	1993
Increased incidence of anti-dsDNA autoantibody concentration in sera of workers occupationally exposed to diisocyanates. Toxicology letters, 1993, Volume: 66, Issue:1 Topics: Adult; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Autoantibodies; Cyanates; DNA; Humans; Isocyanates; Male; Middle Aged; Occupational Exposure; Toluene 2,4-Diisocyanate	1993
Cancer incidence and mortality in the Swedish polyurethane foam manufacturing industry. British journal of industrial medicine, 1993, Volume: 50, Issue:6 Topics: Adult; Aged; Cause of Death; Chemical Industry; Cohort Studies; Cyanates; Female; Humans; Incidence; Isocyanates; Male; Middle Aged; Neoplasms; Occupational Diseases; Occupational Exposure; Sweden; Time Factors; Toluene 2,4-Diisocyanate	1993
Comparison of the binding potential of various diisocyanates on DNA in vitro. Journal of toxicology and environmental health, 1997, Dec-26, Volume: 52, Issue:6 Topics: Animals; Cattle; Chemical Phenomena; Chemistry, Physical; Cyanates; DNA; Isocyanates; Nucleic Acid Conformation; Nucleic Acid Denaturation; Toluene 2,4-Diisocyanate	1997
Diisocyanate antigen-enhanced production of monocyte chemoattractant protein-1, IL-8, and tumor necrosis factor-alpha by peripheral mononuclear cells of workers with occupational asthma. The Journal of allergy and clinical immunology, 1998, Volume: 102, Issue:2 Topics: Adult; Antigens; Asthma; Biomarkers, Tumor; Chemokine CCL2; Chemokines; Cyanates; Female; Humans; Interleukin-8; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha; Tumor Protein, Translationally-Controlled 1	1998
Chemical behaviour of seven aromatic diisocyanates (toluenediisocyanates and diphenylmethanediisocyanates) under in vitro conditions in relationship to their results in the Salmonella/microsome test. Mutation research, 1999, Jan-13, Volume: 438, Issue:2 Topics: Animals; Drug Stability; Isocyanates; Male; Microsomes, Liver; Mutagenicity Tests; Rats; Rats, Sprague-Dawley; Toluene 2,4-Diisocyanate	1999
Subchronic exposure to diisocyanates increases guinea pig tracheal smooth muscle responses to acetylcholine. Respiration; international review of thoracic diseases, 1999, Volume: 66, Issue:2 Topics: Acetylcholine; Animals; Culture Techniques; Cyanates; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Isocyanates; Lung Diseases; Muscle Contraction; Muscle, Smooth; Reference Values; Toluene 2,4-Diisocyanate; Trachea	1999
Specific IgG response to monomeric and polymeric diphenylmethane diisocyanate conjugates in subjects with respiratory reactions to isocyanates. The Journal of allergy and clinical immunology, 1999, Volume: 103, Issue:5 Pt 1 Topics: Adult; Allergens; Antibody Specificity; Asthma; Cross Reactions; Female; Forced Expiratory Volume; Humans; Immunoglobulin G; Isocyanates; Male; Middle Aged; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate	1999
Increase in airway hyperresponsiveness among workers exposed to methylene diphenyldiisocyanate compared to workers exposed to toluene diisocyanate at a petrochemical plant in Korea. American journal of industrial medicine, 2000, Volume: 37, Issue:6 Topics: Adult; Air Pollutants, Occupational; Allergens; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chemical Industry; Female; Forced Expiratory Volume; Humans; Intradermal Tests; Isocyanates; Korea; Male; Occupational Diseases; Petroleum; Toluene 2,4-Diisocyanate	2000
Long-term follow-up of hexamethylene diisocyanate-, diphenylmethane diisocyanate-, and toluene diisocyanate-induced asthma. American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:2 Pt 1 Topics: Adult; Air Pollutants; Allergens; Asthma; Cyanates; Female; Follow-Up Studies; Humans; Immunoglobulin E; Isocyanates; Male; Surveys and Questionnaires; Toluene 2,4-Diisocyanate	2000
Asthma from diisocyanates is not mediated through a Type IV, patch-test-positive mechanism. Contact dermatitis, 2001, Volume: 44, Issue:4 Topics: Adult; Allergens; Asthma; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Hand Dermatoses; Humans; Isocyanates; Male; Middle Aged; Paint; Patch Tests; Toluene 2,4-Diisocyanate	2001
Mechanisms of isocyanate sensitisation. An in vitro approach. Toxicology in vitro : an international journal published in association with BIBRA, 2001, Volume: 15, Issue:6 Topics: Cyanates; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Isocyanates; Monocytes; Peroxides; Respiratory Burst; Toluene 2,4-Diisocyanate; Tumor Cells, Cultured	2001
Assessment of preferential Th1 or Th2 induction by low-molecular-weight compounds using a reverse transcription-polymerase chain reaction method: comparison of two mouse strains, C57BL/6 and BALB/c. Toxicology and applied pharmacology, 2001, Nov-15, Volume: 177, Issue:1 Topics: Allergens; Animals; Dinitrochlorobenzene; Dinitrofluorobenzene; DNA Primers; Interleukin-12; Interleukin-4; Isocyanates; Local Lymph Node Assay; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Weight; Oxazoles; Phthalic Anhydrides; Picryl Chloride; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Species Specificity; Th1 Cells; Th2 Cells; Toluene 2,4-Diisocyanate	2001
Fate and potential environmental effects of methylenediphenyl diisocyanate and toluene diisocyanate released into the atmosphere. Journal of the Air & Waste Management Association (1995), 2003, Volume: 53, Issue:1 Topics: Aerosols; Air Pollutants; Atmosphere; Environmental Monitoring; Forecasting; Humans; Isocyanates; Oxidation-Reduction; Toluene 2,4-Diisocyanate; Water	2003
Effects of thermal degradation products from polyurethane foams based on toluene diisocyanate and diphenylmethane diisocyanate on isolated, perfused lung of guinea pig. Scandinavian journal of work, environment & health, 2003, Volume: 29, Issue:2 Topics: Aerosols; Air Pollutants, Occupational; Animals; Chemical Industry; Disease Models, Animal; Environmental Monitoring; Female; Guinea Pigs; Hot Temperature; Isocyanates; Lung; Male; Perfusion; Polyurethanes; Probability; Risk Assessment; Toluene 2,4-Diisocyanate	2003
DNA strand breaks in the lymphocytes of workers exposed to diisocyanates: indications of individual differences in susceptibility after low-dose and short-term exposure. Archives of toxicology, 2005, Volume: 79, Issue:6 Topics: Adult; Air Pollutants, Occupational; Comet Assay; Cyanates; Disease Susceptibility; DNA Damage; Dose-Response Relationship, Drug; Female; Humans; Isocyanates; Lymphocytes; Male; Middle Aged; Occupational Exposure; Time Factors; Toluene 2,4-Diisocyanate	2005
Chemical analysis of 2,4-toluene diisocyanate, 1,6-hexamethylene diisocyanate and isophorone diisocyanate in petrolatum patch-test preparations. Dermatitis : contact, atopic, occupational, drug, 2005, Volume: 16, Issue:3 Topics: Cyanates; Humans; Isocyanates; Patch Tests; Petrolatum; Reproducibility of Results; Toluene 2,4-Diisocyanate	2005
Evaluation of antibody binding to diisocyanate protein conjugates in a general population. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:3 Topics: Adolescent; Adult; Antibody Specificity; Cyanates; Environmental Exposure; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Prevalence; Toluene 2,4-Diisocyanate	2006
Active single-drop microextraction for the determination of gaseous diisocyanates. Journal of chromatography. A, 2008, Mar-28, Volume: 1185, Issue:2 Topics: Chromatography, High Pressure Liquid; Cyanates; Isocyanates; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Toluene 2,4-Diisocyanate; Water	2008
Contact sensitization to 4,4'-diaminodiphenylmethane and to isocyanates among general dermatology patients. Contact dermatitis, 2008, Volume: 59, Issue:2 Topics: Allergens; Cyanates; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Finland; Humans; Isocyanates; Male; Patch Tests; Risk Factors; Toluene 2,4-Diisocyanate	2008
Dermal uptake and excretion of 14C-toluene diisocyante (TDI) and 14C-methylene diphenyl diisocyanate (MDI) in male rats. Clinical signs and histopathology following dermal exposure of male rats to TDI. Toxicology letters, 2010, Dec-15, Volume: 199, Issue:3 Topics: Animals; Carbon Radioisotopes; Isocyanates; Male; Rats; Rats, Wistar; Skin; Toluene 2,4-Diisocyanate	2010
Micronuclei, hemoglobin adducts and respiratory tract irritation in mice after inhalation of toluene diisocyanate (TDI) and 4,4'-methylenediphenyl diisocyanate (MDI). Mutation research, 2011, Jul-14, Volume: 723, Issue:1 Topics: Administration, Inhalation; Aerosols; Animals; Hemoglobins; Isocyanates; Male; Mice; Mice, Inbred C57BL; Micronucleus Tests; Mutagens; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate	2011
Occupational contact allergy to monomeric isocyanates. Contact dermatitis, 2012, Volume: 67, Issue:2 Topics: Allergens; Aniline Compounds; Cyanates; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Humans; Isocyanates; Male; Occupations; Toluene 2,4-Diisocyanate	2012
Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma. Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 129, Issue:1 Topics: Adult; Antioxidants; Asthma; Canada; Cyanates; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Isocyanates; Male; Toluene 2,4-Diisocyanate	2012
Biomarkers of exposure in Monday morning urine samples as a long-term measure of exposure to aromatic diisocyanates. International archives of occupational and environmental health, 2014, Volume: 87, Issue:4 Topics: Air Pollutants, Occupational; Biomarkers; Environmental Monitoring; Female; Genotype; Glutathione Transferase; Humans; Isocyanates; Male; Occupational Exposure; Polymorphism, Genetic; Sweden; Toluene 2,4-Diisocyanate	2014
Development of sandwich ELISAs for the detection of aromatic diisocyanate adducts. Journal of immunological methods, 2013, Nov-29, Volume: 397, Issue:1-2 Topics: Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Humans; Isocyanates; Serum Albumin; Toluene 2,4-Diisocyanate	2013
Toluene diisocyanate and methylene diphenyl diisocyanate: asthmatic response and cross-reactivity in a mouse model. Archives of toxicology, 2016, Volume: 90, Issue:7 Topics: Air Pollutants, Occupational; Animals; Asthma; Cross Reactions; Disease Models, Animal; Immunoglobulin E; Isocyanates; Male; Mice, Inbred C57BL; Th1-Th2 Balance; Toluene 2,4-Diisocyanate	2016
Development of a method for quantification of toluene diisocyanate and methylenediphenyl diisocyanate migration from polyurethane foam sample surface to artificial sweat by HPLC-UV-MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Apr-01, Volume: 1142 Topics: Air Pollutants, Occupational; Chromatography, High Pressure Liquid; Environmental Exposure; Environmental Monitoring; Humans; Isocyanates; Movement; Paint; Polyurethanes; Surface Properties; Sweat; Tandem Mass Spectrometry; Toluene 2,4-Diisocyanate	2020
Isocyanates may contribute to allergic contact dermatitis from diabetes devices and wound dressings. Contact dermatitis, 2022, Volume: 87, Issue:5 Topics: Allergens; Amines; Bandages; Dermatitis, Allergic Contact; Diabetes Mellitus; Humans; Isocyanates; Polyurethanes; Toluene 2,4-Diisocyanate	2022