Page last updated: 2024-08-18

4,4'-diphenylmethane diisocyanate and 4,4'-diaminodiphenylmethane

4,4'-diphenylmethane diisocyanate has been researched along with 4,4'-diaminodiphenylmethane in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's8 (38.10)18.2507
2000's6 (28.57)29.6817
2010's5 (23.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kajiyama, T; Takahara, A; Takayanagi, M; Tashita, J1
Lipski, K1
Shuker, D1
Heinrich, U; Henschler, D; Hoymann, HG; Sabbioni, G; Schütze, D; Sepai, O1
Henschler, D; Lewalter, J; Miksche, L; Sabbioni, G; Schütze, D; Sepai, O1
Dalene, M; Skarping, G1
Bruynzeel, DP; van der Wegen-Keijser, MH1
Heinrich, U; Hoymann, HG; Lutz, WK; Vock, EH1
Dalene, M; Hagmar, L; Jakobsson, K; Rannug, A; Skarping, G1
Gahlmann, R; Lutz, WK; Vamvakas, S; Vock, EH1
Hartley, R; Henschler, D; Höllrigl-Rosta, A; Koeber, R; Sabbioni, G; Schneider, S1
Siegel, PD; Zhong, BZ1
Hirvonen, A; Kääriä, K; Norppa, H; Piirilä, P; Rosenberg, C; Vainio, H1
Depree, GJ; Siegel, PD; Zhong, BZ1
Brown, WE; Hext, P; Leibold, E; Leng, G; Pauluhn, J1
Bruze, M; Frick-Engfeldt, M; Isaksson, M; Zimerson, E1
Axelsson, S; Bruze, M; Engfeldt, M; Hamada, H; Isaksson, M; Jönsson, B; Liljelind, I; Tinnerberg, H; Zimerson, E1
Aalto-Korte, K; Henriks-Eckerman, ML; Jolanki, R; Kuuliala, O; Suuronen, K1
Bruze, M; Engfeldt, M; Goossens, A; Isaksson, M; Zimerson, E1
Bruze, M; Engfeldt, M; Hamada, H; Isaksson, M; Zimerson, E1
Gagné, S; Lépine, M; Lesage, J; Sleno, L1

Other Studies

21 other study(ies) available for 4,4'-diphenylmethane diisocyanate and 4,4'-diaminodiphenylmethane

ArticleYear
Effect of aggregation state of hard segment in segmented poly(urethaneureas) on their fatigue behavior after interaction with blood components.
    Journal of biomedical materials research, 1985, Volume: 19, Issue:1

    Topics: Absorption; Aniline Compounds; Biocompatible Materials; Biomechanical Phenomena; Blood; Calorimetry, Differential Scanning; Cyanates; Elasticity; Glycols; Isocyanates; Lipids; Polymers; Polyurethanes; Scattering, Radiation; Serum Albumin; Solubility; Spectrophotometry, Infrared; Temperature; Viscosity; X-Ray Diffraction

1985
Liquid chromatographic determination of dimethyl formamide, methylene bisphenyl isocyanate and methylene bisphenyl amine in air samples.
    The Annals of occupational hygiene, 1982, Volume: 25, Issue:1

    Topics: Air Pollutants; Air Pollutants, Occupational; Aniline Compounds; Chromatography, High Pressure Liquid; Cyanates; Dimethylformamide; Isocyanates

1982
Metabolites beat adducts and monitors.
    Human & experimental toxicology, 1995, Volume: 14, Issue:8

    Topics: Aniline Compounds; Carcinogens; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Isocyanates; Occupational Exposure; Risk Factors; Sensitivity and Specificity

1995
Hemoglobin adducts and urine metabolites of 4,4'-methylenedianiline after 4,4'-methylenediphenyl diisocyanate exposure of rats.
    Chemico-biological interactions, 1995, Jul-14, Volume: 97, Issue:2

    Topics: Acetanilides; Administration, Inhalation; Aniline Compounds; Animals; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Female; Hemoglobins; Isocyanates; Rats; Rats, Wistar

1995
Biomonitoring of workers exposed to 4,4'-methylenedianiline or 4,4'-methylenediphenyl diisocyanate.
    Carcinogenesis, 1995, Volume: 16, Issue:3

    Topics: Aniline Compounds; Carcinogens; Chromatography, High Pressure Liquid; Electrochemistry; Hemoglobins; Humans; Isocyanates; Occupational Exposure

1995
Determination of 4,4'-methylenediphenyldianiline (MDA) and identification of isomers in technical-grade MDA in hydrolysed plasma and urine from workers exposed to methylene diphenyldiisocyanate by gas chromatography-mass spectrometry.
    Journal of chromatography. B, Biomedical applications, 1995, Jan-20, Volume: 663, Issue:2

    Topics: Allergens; Aniline Compounds; Chemical Industry; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Isocyanates; Isomerism; Methylation; Occupational Exposure; Polyurethanes; Specimen Handling

1995
Contact dermatitis in a cast technician.
    Contact dermatitis, 1993, Volume: 28, Issue:3

    Topics: Adult; Aniline Compounds; Casts, Surgical; Cyanates; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Hand Dermatoses; Humans; Isocyanates

1993
32P-postlabeling of a DNA adduct derived from 4,4'-methylenedianiline, in the olfactory epithelium of rats exposed by inhalation to 4,4'-methylenediphenyl diisocyanate.
    Carcinogenesis, 1996, Volume: 17, Issue:5

    Topics: Administration, Inhalation; Aniline Compounds; Animals; Carcinogens; DNA Adducts; Female; Isocyanates; Male; Nasal Mucosa; Phosphorus Radioisotopes; Rats; Rats, Inbred F344; Rats, Wistar

1996
MDA in plasma as a biomarker of exposure to pyrolysed MDI-based polyurethane: correlations with estimated cumulative dose and genotype for N-acetylation.
    International archives of occupational and environmental health, 1996, Volume: 68, Issue:3

    Topics: Acetylation; Adult; Analysis of Variance; Aniline Compounds; Arylamine N-Acetyltransferase; Biomarkers; Gas Chromatography-Mass Spectrometry; Genotype; Humans; Isocyanates; Male; Middle Aged; Occupational Exposure; Polymerase Chain Reaction; Polyurethanes; Welding

1996
Investigation of the induction of DNA double-strand breaks by methylenediphenyl-4-4'-diisocyanate in cultured human lung epithelial cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 46, Issue:1

    Topics: Aniline Compounds; Carcinogens; Cell Nucleus; Cell Survival; Cells, Cultured; DNA; DNA Damage; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Humans; Isocyanates; Lung; Melphalan; Molecular Weight; Octoxynol

1998
Isocyanate-specific hemoglobin adduct in rats exposed to 4, 4'-methylenediphenyl diisocyanate.
    Chemical research in toxicology, 2000, Volume: 13, Issue:2

    Topics: Acetanilides; Allergens; Aniline Compounds; Animals; Biomarkers; Gas Chromatography-Mass Spectrometry; Hemoglobins; Isocyanates; Peptide Fragments; Rats; Valine

2000
Induction of micronuclei following exposure to methylene di-phenyl diisocyanate: potential genotoxic metabolites.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 58, Issue:1

    Topics: Aerosols; Aniline Compounds; Animals; Bone Marrow Cells; Carcinogens; Cell Line; Cricetinae; Cysteine; Dose-Response Relationship, Drug; Erythrocytes; Fibroblasts; Glutathione; Inhalation Exposure; Isocyanates; Micronucleus Tests; Microsomes, Liver; Mutagens; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley

2000
Exposure to 4,4'-methylenediphenyl diisocyanate (MDI) during moulding of rigid polyurethane foam: determination of airborne MDI and urinary 4,4'-methylenedianiline (MDA).
    The Analyst, 2001, Volume: 126, Issue:4

    Topics: Adult; Air Pollutants, Occupational; Aniline Compounds; Female; Humans; Isocyanates; Male; Middle Aged; Occupational Exposure; Polyurethanes

2001
Differentiation of the mechanism of micronuclei induced by cysteine and glutathione conjugates of methylenedi-p-phenyl diisocyanate from that of 4,4'-methylenedianiline.
    Mutation research, 2001, Oct-18, Volume: 497, Issue:1-2

    Topics: Aniline Compounds; Animals; Cell Line; Cricetinae; Cysteine; Glutathione; Isocyanates; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Spindle Apparatus

2001
Analysis of biomarkers in rats and dogs exposed to polymeric methylenediphenyl diisocyanate (pMDI) and its glutathione adduct.
    Toxicology, 2006, May-15, Volume: 222, Issue:3

    Topics: Acetanilides; Aniline Compounds; Animals; Benzhydryl Compounds; Biomarkers; Blood Proteins; Dogs; Glutathione; Hemoglobins; Isocyanates; Male; Polyurethanes; Protein Binding; Rats; Rats, Wistar

2006
How to optimize patch testing with diphenylmethane diisocyanate.
    Contact dermatitis, 2007, Volume: 57, Issue:3

    Topics: Adolescent; Adult; Aniline Compounds; Dermatitis, Allergic Contact; Drug Stability; Female; Humans; Isocyanates; Male; Middle Aged; Patch Tests; Polyurethanes; Time Factors

2007
Dermal uptake study with 4,4'-diphenylmethane diisocyanate led to active sensitization.
    Contact dermatitis, 2012, Volume: 66, Issue:2

    Topics: Administration, Cutaneous; Adult; Aniline Compounds; Dermatitis, Allergic Contact; Eczema; Female; Humans; Isocyanates; Patch Tests; Petrolatum; Skin Absorption; Time Factors; Young Adult

2012
Occupational contact allergy to monomeric isocyanates.
    Contact dermatitis, 2012, Volume: 67, Issue:2

    Topics: Allergens; Aniline Compounds; Cyanates; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Humans; Isocyanates; Male; Occupations; Toluene 2,4-Diisocyanate

2012
The outcome of 9 years of consecutive patch testing with 4,4'-diaminodiphenylmethane and 4,4'-diphenylmethane diisocyanate.
    Contact dermatitis, 2013, Volume: 68, Issue:2

    Topics: Allergens; Aniline Compounds; Belgium; Cohort Studies; Dermatitis, Allergic Contact; Dermatitis, Occupational; Disease Outbreaks; Humans; Isocyanates; Patch Tests; Sweden

2013
Sensitization and cross-reactivity patterns of contact allergy to diisocyanates and corresponding amines: investigation of diphenylmethane-4,4'-diisocyanate, diphenylmethane-4,4'-diamine, dicyclohexylmethane-4,4'-diisocyanate, and dicylohexylmethane-4,4'-
    Contact dermatitis, 2017, Volume: 77, Issue:4

    Topics: Allergens; Amines; Aniline Compounds; Animals; Benzhydryl Compounds; Cross Reactions; Cyanates; Cyclohexanes; Cyclohexylamines; Dermatitis, Allergic Contact; Diamines; Guinea Pigs; Humans; Isocyanates; Patch Tests; Polyurethanes

2017
A validated liquid chromatography/tandem mass spectrometry method for 4,4'-methylenedianiline quantitation in human urine as a measure of 4,4'-methylene diphenyl diisocyanate exposure.
    Rapid communications in mass spectrometry : RCM, 2019, Mar-30, Volume: 33, Issue:6

    Topics: Aniline Compounds; Calibration; Chromatography, Liquid; Humans; Hydrolysis; Isocyanates; Limit of Detection; Liquid-Liquid Extraction; Occupational Exposure; Tandem Mass Spectrometry

2019