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4,4'-diphenylmethane diisocyanate and 1,6-hexamethylene diisocyanate

4,4'-diphenylmethane diisocyanate has been researched along with 1,6-hexamethylene diisocyanate in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199010 (27.78)18.7374
1990's6 (16.67)18.2507
2000's15 (41.67)29.6817
2010's5 (13.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arai, Y; Fukushima, N; Hosojima, T; Matsuzaki, G; Miyamoto, Y; Sano, Y; Suko, M; Suzuki, N1
Cartier, A; Grammer, LC; Harris, KE; Malo, JL; Patterson, R1
Belin, L; Wass, U1
Cartier, A; Ghezzo, H; Grammer, L; Harris, K; Lagier, F; Malo, JL; Patterson, R1
Baur, X; Fruhmann, G1
Baur, X1
Butcher, BT1
Baur, X; Dewair, M; Mauermayer, R1
Cartier, A; Levitz, D; Malo, JL; Ouimet, G; Zeiss, CR1
Laitinen, J; Muittari, A; Sovijärvi, A1
Alarie, Y; Karol, MH2
Baur, X; Czuppon, AB; Hartmann, R; Marczynski, B; Scheer, E1
Baur, X; Marczynski, B; Peel, M1
Alam, R; Bernstein, DI; Bernstein, JA; Lummus, ZL1
Baur, X; Marczynski, B; Marek, W; Mensing, T; Potthast, J1
Dalene, M; Littorin, M; Rylander, L; Skarping, G; Skerfving, S; Strömberg, U; Welinder, H1
Keskinen, HM; Luukkonen, R; Nordman, H; Piirilä, PL; Salo, SP; Tuomi, TO; Tuppurainen, M1
Beckett, PN; Curran, AD; Elms, J; Griffin, P1
Redlich, CA; Wisnewski, AV1
Gordon, T; Redlich, CA; Wisnewski, AV1
Labow, RS; Santerre, JP; Tang, YW1
Liu, Q; Wisnewski, AV1
Labow, RS; Matheson, LA; Santerre, JP1
Johnson, VJ; Luster, MI; Matheson, JM1
Bracht, A; Brüning, T; Haufs, MG; Käfferlein, HU; Kappler, M; Marczynski, B; Mensing, T; Merget, R; Rabstein, S1
Dalene, M; Karlsson, D; Marand, A; Skarping, G1
Bruze, M; Frick-Engfeldt, M; Isaksson, M; Karlsson, D; Marand, A; Skarping, G; Zimerson, E1
Bernstein, DI; Graham, C; Lummus, Z; Ott, MG; Woolhiser, M1
Batlle, R; Crescenzi, C; López, P; Nerín, C1
Lammintausta, K; Liippo, J1
Aalto-Korte, K; Henriks-Eckerman, ML; Jolanki, R; Kuuliala, O; Suuronen, K1
Bernstein, DI; Boulet, LP; Cartier, A; Cruz, MJ; Fluharty, K; Gautrin, D; Germolec, DR; Johnson, VJ; Kissling, GE; Lummus, ZL; Luster, MI; Malo, JL; Munoz, X; Quirce, S; Sastre, J; Tarlo, SM; Yucesoy, B1
Fan, Y; Gao, H; Ma, J; Sun, Y; Sun, YL; Wang, A; Wang, Y; Wu, G; Yang, YW1
Adewuyi, GO; Guo, QJ; Okoli, CP1
Liu, J; Nassar, AF; Wisnewski, AV1

Reviews

4 review(s) available for 4,4'-diphenylmethane diisocyanate and 1,6-hexamethylene diisocyanate

ArticleYear
Recent developments in diisocyanate asthma.
    Current opinion in allergy and clinical immunology, 2001, Volume: 1, Issue:2

    Topics: Asthma; Cyanates; Genes, MHC Class II; Genetic Predisposition to Disease; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Skin; T-Lymphocytes, Helper-Inducer; Toluene 2,4-Diisocyanate

2001
Mouse models of diisocyanate asthma.
    American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:4

    Topics: Allergens; Animals; Asthma; Cyanates; Disease Models, Animal; Isocyanates; Mice; Models, Biological; Models, Chemical; Toluene 2,4-Diisocyanate

2002
Recent developments in diisocyanate asthma.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:5 Suppl 2

    Topics: Asthma; Cyanates; Epithelial Cells; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Isocyanates; Lung; Occupational Diseases; Occupational Exposure; Skin; Toluene 2,4-Diisocyanate

2003
Animal models for diisocyanate asthma: answers for lingering questions.
    Current opinion in allergy and clinical immunology, 2004, Volume: 4, Issue:2

    Topics: Air Pollutants, Occupational; Allergens; Animals; Asthma; Cyanates; Humans; Isocyanates; Occupational Diseases

2004

Other Studies

32 other study(ies) available for 4,4'-diphenylmethane diisocyanate and 1,6-hexamethylene diisocyanate

ArticleYear
[A case of hypersensitivity pneumonitis in which serum specific antibodies for three species of isocyanate molecules were demonstrated].
    Nihon Kyobu Shikkan Gakkai zasshi, 1992, Volume: 30, Issue:3

    Topics: Alveolitis, Extrinsic Allergic; Antibodies; Cyanates; Humans; Isocyanates; Male; Middle Aged; Paint; Toluene 2,4-Diisocyanate

1992
The use of an immunoassay index for antibodies against isocyanate human protein conjugates and application to human isocyanate disease.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:1

    Topics: Antibodies; Antibody Specificity; Blood Proteins; Cyanates; Enzyme-Linked Immunosorbent Assay; Haptens; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate

1990
Immunologic specificity of isocyanate-induced IgE antibodies in serum from 10 sensitized workers.
    The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:1

    Topics: Antibody Specificity; Asthma; Carrier Proteins; Cyanates; Haptens; Humans; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Toluene 2,4-Diisocyanate

1989
Specific serum antibodies against isocyanates: association with occupational asthma.
    The Journal of allergy and clinical immunology, 1989, Volume: 84, Issue:4 Pt 1

    Topics: Antibodies; Asthma; Cyanates; Female; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Male; Occupational Diseases; Skin Tests

1989
Specific IgE antibodies in patients with isocyanate asthma.
    Chest, 1981, Volume: 80, Issue:1 Suppl

    Topics: Antibodies; Asthma; Benzhydryl Compounds; Cyanates; Humans; Immunoglobulin E; Isocyanates; Toluene 2,4-Diisocyanate

1981
Immunologic cross-reactivity between different albumin-bound isocyanates.
    The Journal of allergy and clinical immunology, 1983, Volume: 71, Issue:2

    Topics: Adult; Aerosols; Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate

1983
Isocyanate induced asthma.
    European journal of respiratory diseases. Supplement, 1982, Volume: 123

    Topics: Asthma; Bronchial Provocation Tests; Cyanates; Forced Expiratory Volume; Humans; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate

1982
Inhibition of acetylcholinesterase by diisocyanates and its spontaneous reactivation.
    International archives of occupational and environmental health, 1983, Volume: 52, Issue:3

    Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cyanates; Dose-Response Relationship, Drug; Environmental Exposure; Erythrocytes; Humans; In Vitro Techniques; Isocyanates; Risk; Software; Toluene 2,4-Diisocyanate

1983
Combined alveolitis and asthma due to hexamethylene diisocyanate (HDI), with demonstration of crossed respiratory and immunologic reactivities to diphenylmethane diisocyanate (MDI).
    The Journal of allergy and clinical immunology, 1983, Volume: 72, Issue:4

    Topics: Alveolitis, Extrinsic Allergic; Asthma; Binding Sites, Antibody; Bronchial Provocation Tests; Cross Reactions; Cyanates; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Paint; Respiratory Function Tests

1983
[Diisocyanate-induced asthma and alveolitis].
    Duodecim; laaketieteellinen aikakauskirja, 1984, Volume: 100, Issue:4

    Topics: Adult; Alveolitis, Extrinsic Allergic; Asthma; Construction Materials; Cyanates; Humans; Isocyanates; Male; Occupational Diseases; Paint; Respiratory Function Tests

1984
Serologic assays for antibodies to HDI and MDI.
    Contact dermatitis, 1981, Volume: 7, Issue:1

    Topics: Antibodies; Benzhydryl Compounds; Cyanates; Humans; Isocyanates; Radioimmunoassay

1981
Serologic assays for antibodies to hexamethylene diisocyanate and diphenylmethane diisocyanate.
    Archives of dermatology, 1981, Volume: 117, Issue:8

    Topics: Antibodies; Benzhydryl Compounds; Cyanates; Humans; Isocyanates; Occupational Diseases

1981
Increased incidence of anti-dsDNA autoantibody concentration in sera of workers occupationally exposed to diisocyanates.
    Toxicology letters, 1993, Volume: 66, Issue:1

    Topics: Adult; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Autoantibodies; Cyanates; DNA; Humans; Isocyanates; Male; Middle Aged; Occupational Exposure; Toluene 2,4-Diisocyanate

1993
Comparison of the binding potential of various diisocyanates on DNA in vitro.
    Journal of toxicology and environmental health, 1997, Dec-26, Volume: 52, Issue:6

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry, Physical; Cyanates; DNA; Isocyanates; Nucleic Acid Conformation; Nucleic Acid Denaturation; Toluene 2,4-Diisocyanate

1997
Diisocyanate antigen-enhanced production of monocyte chemoattractant protein-1, IL-8, and tumor necrosis factor-alpha by peripheral mononuclear cells of workers with occupational asthma.
    The Journal of allergy and clinical immunology, 1998, Volume: 102, Issue:2

    Topics: Adult; Antigens; Asthma; Biomarkers, Tumor; Chemokine CCL2; Chemokines; Cyanates; Female; Humans; Interleukin-8; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha; Tumor Protein, Translationally-Controlled 1

1998
Subchronic exposure to diisocyanates increases guinea pig tracheal smooth muscle responses to acetylcholine.
    Respiration; international review of thoracic diseases, 1999, Volume: 66, Issue:2

    Topics: Acetylcholine; Animals; Culture Techniques; Cyanates; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Isocyanates; Lung Diseases; Muscle Contraction; Muscle, Smooth; Reference Values; Toluene 2,4-Diisocyanate; Trachea

1999
Exposure biomarkers and risk from gluing and heating of polyurethane: a cross sectional study of respiratory symptoms.
    Occupational and environmental medicine, 2000, Volume: 57, Issue:6

    Topics: Adhesives; Adult; Biomarkers; Cross-Sectional Studies; Cyanates; Female; Humans; Immunoglobulin G; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Polyurethanes; Respiration Disorders; Risk Assessment

2000
Long-term follow-up of hexamethylene diisocyanate-, diphenylmethane diisocyanate-, and toluene diisocyanate-induced asthma.
    American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:2 Pt 1

    Topics: Adult; Air Pollutants; Allergens; Asthma; Cyanates; Female; Follow-Up Studies; Humans; Immunoglobulin E; Isocyanates; Male; Surveys and Questionnaires; Toluene 2,4-Diisocyanate

2000
Mechanisms of isocyanate sensitisation. An in vitro approach.
    Toxicology in vitro : an international journal published in association with BIBRA, 2001, Volume: 15, Issue:6

    Topics: Cyanates; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Isocyanates; Monocytes; Peroxides; Respiratory Burst; Toluene 2,4-Diisocyanate; Tumor Cells, Cultured

2001
Enzyme induced biodegradation of polycarbonate-polyurethanes: dose dependence effect of cholesterol esterase.
    Biomaterials, 2003, Volume: 24, Issue:12

    Topics: Cyanates; Dose-Response Relationship, Drug; Enzymes; Hydrolysis; Isocyanates; Polycarboxylate Cement; Polymers; Polyurethanes; Protein Binding; Sterol Esterase; Temperature

2003
Changes in macrophage function and morphology due to biomedical polyurethane surfaces undergoing biodegradation.
    Journal of cellular physiology, 2004, Volume: 199, Issue:1

    Topics: Absorbable Implants; Cyanates; Electrophoresis, Polyacrylamide Gel; Esterases; Giant Cells, Foreign-Body; Humans; Immunoblotting; Isocyanates; Macrophage Activation; Microscopy, Electron, Scanning; Polyurethanes; Precipitin Tests; Sterol Esterase; Surface Properties; U937 Cells

2004
DNA strand breaks in the lymphocytes of workers exposed to diisocyanates: indications of individual differences in susceptibility after low-dose and short-term exposure.
    Archives of toxicology, 2005, Volume: 79, Issue:6

    Topics: Adult; Air Pollutants, Occupational; Comet Assay; Cyanates; Disease Susceptibility; DNA Damage; Dose-Response Relationship, Drug; Female; Humans; Isocyanates; Lymphocytes; Male; Middle Aged; Occupational Exposure; Time Factors; Toluene 2,4-Diisocyanate

2005
Solvent-free sampling with di-n-butylamine for monitoring of isocyanates in air.
    Journal of environmental monitoring : JEM, 2005, Volume: 7, Issue:4

    Topics: Acetic Acid; Air Pollutants; Air Pollution, Indoor; Butylamines; Cyanates; Environmental Monitoring; Filtration; Humidity; Isocyanates; Particle Size; Reproducibility of Results; Temperature

2005
Chemical analysis of 2,4-toluene diisocyanate, 1,6-hexamethylene diisocyanate and isophorone diisocyanate in petrolatum patch-test preparations.
    Dermatitis : contact, atopic, occupational, drug, 2005, Volume: 16, Issue:3

    Topics: Cyanates; Humans; Isocyanates; Patch Tests; Petrolatum; Reproducibility of Results; Toluene 2,4-Diisocyanate

2005
Evaluation of antibody binding to diisocyanate protein conjugates in a general population.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:3

    Topics: Adolescent; Adult; Antibody Specificity; Cyanates; Environmental Exposure; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Prevalence; Toluene 2,4-Diisocyanate

2006
Active single-drop microextraction for the determination of gaseous diisocyanates.
    Journal of chromatography. A, 2008, Mar-28, Volume: 1185, Issue:2

    Topics: Chromatography, High Pressure Liquid; Cyanates; Isocyanates; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Toluene 2,4-Diisocyanate; Water

2008
Contact sensitization to 4,4'-diaminodiphenylmethane and to isocyanates among general dermatology patients.
    Contact dermatitis, 2008, Volume: 59, Issue:2

    Topics: Allergens; Cyanates; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Finland; Humans; Isocyanates; Male; Patch Tests; Risk Factors; Toluene 2,4-Diisocyanate

2008
Occupational contact allergy to monomeric isocyanates.
    Contact dermatitis, 2012, Volume: 67, Issue:2

    Topics: Allergens; Aniline Compounds; Cyanates; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Humans; Isocyanates; Male; Occupations; Toluene 2,4-Diisocyanate

2012
Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma.
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 129, Issue:1

    Topics: Adult; Antioxidants; Asthma; Canada; Cyanates; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Isocyanates; Male; Toluene 2,4-Diisocyanate

2012
Temperature- and pH-responsive nanoparticles of biocompatible polyurethanes for doxorubicin delivery.
    International journal of pharmaceutics, 2013, Jan-30, Volume: 441, Issue:1-2

    Topics: Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Cell Line, Tumor; Crystallization; Cyanates; Doxorubicin; Drug Carriers; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen-Ion Concentration; Isocyanates; Liver Neoplasms; Molecular Weight; Nanoparticles; Particle Size; Polyurethanes; Temperature

2013
Application of quantum descriptors for predicting adsorption performance of starch and cyclodextrin adsorbents.
    Carbohydrate polymers, 2014, Jan-30, Volume: 101

    Topics: Adsorption; Cyclodextrins; Epichlorohydrin; Isocyanates; Models, Molecular; Molecular Conformation; Quantum Theory; Reproducibility of Results; Starch; Water

2014
In vitro cleavage of diisocyanate-glutathione conjugates by human gamma-glutamyl transpeptidase-1.
    Xenobiotica; the fate of foreign compounds in biological systems, 2016, Volume: 46, Issue:8

    Topics: Acetylcysteine; gamma-Glutamyltransferase; Glutathione; Humans; Isocyanates; Xenobiotics

2016