Page last updated: 2024-08-26

4,4'-dihydroxystilbene and stilbenes

4,4'-dihydroxystilbene has been researched along with stilbenes in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's10 (62.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Fradinger, EA; Galbreath, M; Garcia, GX; Isovitsch, R; Larsen, SW; Pye, C1
Sinsheimer, JE; Tay, LK1
Forti, L; Hübscher, U; Locatelli, GA; Maga, G; Ramadan, K; Savio, M; Shevelev, I; Spadari, S; Stivala, LA; Vannini, V1
Balan, KV; Chen, JC; Chen, SW; Han, Z; Liu, ZL; Pantazis, P; Wang, Y; Wyche, JH; Yang, L; Zheng, LF1
Dai, F; Fan, GJ; Fang, JG; Jin, XL; Li, XZ; Liu, XD; Qian, YP; Shang, YJ; Zhou, B1
Mikulski, D; Molski, M1
Bianchi, L; Cazzalini, O; Coppa, T; Forti, L; Lazzè, MC; Maccario, C; Perucca, P; Pizzala, R; Savio, M; Stivala, LA; Vannini, V1
Bianchi, L; Ferraro, D; Forti, L; Maccario, C; Pizzala, R; Pretali, L; Savio, M; Stivala, LA1
Bao, XZ; Dai, F; Du, YT; Jin, XL; Kang, YF; Li, XZ; Liu, Q; Ren, XR; Wang, HB; Yan, WJ; Yuan, CH; Zhang, J; Zhou, B; Zhou, TW1
Chen, W; Elhennawy, MG; Lin, HS; Xiang, X; Yeo, SC1
Bianchi, L; Cao, Y; Corana, F; Ferraro, D; Jensen, LD; Maccario, C; Mannucci, B; Savio, M; Stivala, LA; Vaccarone, R1
Bandyopadhyay, SK; Chattopadhyay, S; Gupta, P; Patro, BS; Ray, J; Saha, B; Subramanian, M1
Chattopadhyay, S; Gupta, P; Pai, GB; Patro, BS; Saha, B; Subramanian, M; Tyagi, M1
Bo, Z; Chen, CW; DePamphilis, ML; Han, Z; Hu, S; Li, Y; Li, Z; Meng, Y; Sun, J; Yen, Y; Zhang, Y; Zhou, W; Zhu, W1
Chen, XM; Dai, F; Li, GH; Li, YR; Lou, HX; Ren, DM; Shen, T; Wang, SQ; Wang, T; Wang, XN; Zhou, B1
Cheng, CY; Gong, SN; Sang, MM; Sun, F; Wang, CN; Yang, JF1

Other Studies

16 other study(ies) available for 4,4'-dihydroxystilbene and stilbenes

ArticleYear
The functional group on (E)-4,4'-disubstituted stilbenes influences toxicity and antioxidative activity in differentiated PC-12 cells.
    Bioorganic & medicinal chemistry letters, 2013, Dec-01, Volume: 23, Issue:23

    Topics: Animals; Antioxidants; Free Radicals; Molecular Structure; PC12 Cells; Rats; Stilbenes; Structure-Activity Relationship

2013
Intestinal bacterial reduction of 4,4'-dihydroxystilbene to 4,4'-dihydroxybibenzyl.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:3

    Topics: Animals; Bacteria; Bibenzyls; Intestines; Male; Oxidation-Reduction; Phenols; Rabbits; Rats; Stilbenes

1975
Inhibition of mammalian DNA polymerases by resveratrol: mechanism and structural determinants.
    The Biochemical journal, 2005, Jul-15, Volume: 389, Issue:Pt 2

    Topics: Amino Acid Sequence; Animals; Binding Sites; DNA Nucleotidyltransferases; DNA Replication; DNA-Directed DNA Polymerase; Humans; Kinetics; Mammals; Molecular Structure; Nucleic Acid Synthesis Inhibitors; Protein Binding; Resveratrol; Stilbenes; Structure-Activity Relationship; Substrate Specificity

2005
Proteasome-independent down-regulation of estrogen receptor-alpha (ERalpha) in breast cancer cells treated with 4,4'-dihydroxy-trans-stilbene.
    Biochemical pharmacology, 2006, Aug-28, Volume: 72, Issue:5

    Topics: Base Sequence; Breast Neoplasms; Cell Line, Tumor; DNA Primers; Down-Regulation; Estradiol; Estrogen Receptor alpha; Humans; Proteasome Endopeptidase Complex; Stilbenes

2006
4,4'-Dihydroxy-trans-stilbene, a resveratrol analogue, exhibited enhanced antioxidant activity and cytotoxicity.
    Bioorganic & medicinal chemistry, 2009, Mar-15, Volume: 17, Issue:6

    Topics: Antioxidants; Cell Line, Tumor; Drug Screening Assays, Antitumor; Erythrocyte Membrane; Humans; Kinetics; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Stilbenes

2009
Quantitative structure-antioxidant activity relationship of trans-resveratrol oligomers, trans-4,4'-dihydroxystilbene dimer, trans-resveratrol-3-O-glucuronide, glucosides: trans-piceid, cis-piceid, trans-astringin and trans-resveratrol-4'-O-beta-D-glucopy
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: Dimerization; Free Radical Scavengers; Glucose; Glucosides; Glucuronides; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Quantum Theory; Resveratrol; Stereoisomerism; Stilbenes

2010
Structure-activity relationship of resveratrol and its analogue, 4,4'-dihydroxy-trans-stilbene, toward the endothelin axis in human endothelial cells.
    Journal of medicinal food, 2011, Volume: 14, Issue:10

    Topics: Antioxidants; Aspartic Acid Endopeptidases; Cell Line; Endothelin-1; Endothelin-Converting Enzymes; Human Umbilical Vein Endothelial Cells; Humans; Lipid Peroxidation; Metalloendopeptidases; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Structure-Activity Relationship

2011
The resveratrol analog 4,4'-dihydroxy-trans-stilbene suppresses transformation in normal mouse fibroblasts and inhibits proliferation and invasion of human breast cancer cells.
    Carcinogenesis, 2012, Volume: 33, Issue:11

    Topics: Adenocarcinoma; Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Cycle; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Collagen Type I; Female; Fibroblasts; Humans; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Stilbenes; Tumor Stem Cell Assay; Wound Healing

2012
Tailoring 3,3'-dihydroxyisorenieratene to hydroxystilbene: finding a resveratrol analogue with increased antiproliferation activity and cell selectivity.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2014, Jul-14, Volume: 20, Issue:29

    Topics: Antineoplastic Agents, Phytogenic; Carotenoids; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Discovery; Humans; Models, Molecular; Resveratrol; Stilbenes

2014
Determination of naturally occurring resveratrol analog trans-4,4'-dihydroxystilbene in rat plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.
    Analytical and bioanalytical chemistry, 2015, Volume: 407, Issue:19

    Topics: Animals; Chromatography, Liquid; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tandem Mass Spectrometry

2015
Resveratrol analogue 4,4'-dihydroxy-trans-stilbene potently inhibits cancer invasion and metastasis.
    Scientific reports, 2016, Feb-01, Volume: 6

    Topics: Animals; Apoptosis; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Male; Mice; Neoplasm Invasiveness; Neoplasms, Experimental; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays

2016
trans-4,4'-Dihydroxystilbene (DHS) protects PC12 cells from oxidative damage but induces reactive oxygen species-mediated apoptosis in SHSY-5Y cell line.
    Indian journal of experimental biology, 2016, Volume: 54, Issue:11

    Topics: Animals; Apoptosis; Cell Survival; Humans; Hydrogen Peroxide; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Stilbenes

2016
Resveratrol analogue, trans-4,4'-dihydroxystilbene (DHS), inhibits melanoma tumor growth and suppresses its metastatic colonization in lungs.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 107

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Skin Neoplasms; Stilbenes

2018
DHS (trans-4,4'-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2).
    Oncogene, 2019, Volume: 38, Issue:13

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; DNA Replication; Enzyme Inhibitors; Female; HCT116 Cells; Humans; Mice; Mice, Nude; Models, Molecular; Molecular Docking Simulation; Neoplasms; Protein Subunits; Ribonucleotide Reductases; Stilbenes; Xenograft Model Antitumor Assays

2019
Trans-4,4'-dihydroxystilbene ameliorates cigarette smoke-induced progression of chronic obstructive pulmonary disease via inhibiting oxidative stress and inflammatory response.
    Free radical biology & medicine, 2020, 05-20, Volume: 152

    Topics: Animals; Kelch-Like ECH-Associated Protein 1; Lung; Mice; NF-E2-Related Factor 2; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Smoking; Stilbenes

2020
Two resveratrol analogs, pinosylvin and 4,4'-dihydroxystilbene, improve oligoasthenospermia in a mouse model by attenuating oxidative stress via the Nrf2-ARE pathway.
    Bioorganic chemistry, 2020, Volume: 104

    Topics: Animals; Antioxidant Response Elements; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Molecular Structure; NF-E2-Related Factor 2; Oligospermia; Oxidative Stress; Stilbenes; Structure-Activity Relationship

2020